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Piluca MD

@pilukaid-md.bsky.social
682 followers 130 following 6 posts

ID consultant. Hospital Ramón y Cajal. Madrid. Spain 🇪🇸… I only use this social network to update and share knowledge about infectious diseases 🦠and other medical sciences

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Reposted by Piluca MD
Outbreak News Today @outbreaknews.bsky.social · 02/10/2026
Russia: 189 people under observation after lab worker dies of possible pneumonic plague outbreaknewstoday.substack.com/p/russia-189...
outbreaknewstoday.substack.com
Russia: 189 people under observation after lab worker dies of possible pneumonic plague
According to Russian media, officials in Siberia’s Irkutsk region have placed nearly 200 people under medical observation after a laboratory worker died from plague.
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Reposted by Piluca MD
Alicia Ault @aliciaault.bsky.social · 02/10/2026
CDC reporting a big increase in cases of a rare fungal disease that primarily attacks the brain and has a 60-70% fatality rate. Increase likely not due to a rise in referrals or detection, per this MMWR paper. #IDSky #EpiSky #NeuroSky #fungusamongus
cdc.gov
Cladophialophora bantiana Detections
This report describes 48 confirmed cases and one probable case of C. bantiana in clinical samples from 2009–2026.
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Ilan Schwartz @germhuntermd.bsky.social · 02/10/2026
Shorter is also better in ICU patients Timsit, Roberts, @angelahuttner.bsky.social, Daneman &c State-of-the-Art in AJRCCM @atsblueeditor.bsky.social For most ICU patients with (suspected) infections, abx can be 🛑 at 5-7d w clinical improvement academic.oup.com/ajrccm/advan... #IDSky #CritCareSky
Duration of antibiotic therapy in sepsis and severe infections in critically ill patients decision pathway. 

Day 1 empiric therapy: sampling (culture) before therapy, clinical exams, consider alternate diagnosis;

48-72h Tailor treatment and switch to targeted therapy where possible, PK optimization, source control

Indications for extended courses: endocarditis (4-6 weeks), brain abscess (6-12 weeks), spondylodiscitis (6-12w), prosthetic joint infection (6-12 w), incomplete removal abscess, empyema, retained prosthesis: individualized

Day 5-7: 

if Patients NOT responding or positive cultures: reassess treatment, individualize according to source control, immune status, high risk microbiology (S aureus, candida), possible suboptimal therapy (MDR), intravascular devices, ? role of serial PCT for stopping early questioned

if Clinical improvement: STOP antibiotics
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SHORTEN-2 trial @shorten2trial.bsky.social · 03/10/2026
The OPTIMISE trial aimed to test 7 vs 14 days for treating MDR infections in ICU patients. Although underpowered due to early stop, no signal of inefficacy was observed for short treatments Pseudomonas were underrepresented in this trial 🙁 link.springer.com/article/10.1... #AMSsky #IDsky #PsWatch
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Outbreak News Today @outbreaknews.bsky.social · 29/09/2026
Italy: West Nile virus cases rise to 700 outbreaknewstoday.substack.com/p/italy-west...
outbreaknewstoday.substack.com
Italy: West Nile virus cases rise to 700
In Italy, since the start of surveillance up to September 23, 2026, 700 confirmed cases of human West Nile Virus (WNV) infection have been reported.
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Reposted by Piluca MD
International Immunocompromised Host Society @ichs-global.bsky.social · 30/09/2026
Tomorrow! Don't miss the experts in this live session. Free registration available at buff.ly/lvEw1A1.
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Reposted by Piluca MD
IDSA @idsainfo.bsky.social · 15/09/2026
In OFID, authors estimate the pooled prevalence of azithromycin resistance in Salmonella Typhi and Salmonella Paratyphi isolates from human populations in South Asia. bit.ly/46XsmCV
bit.ly
Azithromycin Resistance in Salmonella Typhi and Paratyphi across South Asia: A Systematic Review and Meta-Analysis
This meta-analysis of 74 South Asian studies involving 30,085 clinical isolates reveals a stable 5% pooled azithromycin resistance for both Salmonella Typh
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Reposted by Piluca MD
Chelsea Gorsline, MD 🦠🍄 @chelseagorsline.bsky.social · 16/09/2026
🚨New pub: TID Tracks - Leveraging Gen ID for TID Training. A pragmatic review of TID training tracks, including program structure, curriculum and extracurricular activities. Part of a series on TID education. Many thanks to editors for invitation to contribute on this important topic! #IDSky
doi.org
Transplant Infectious Diseases Tracks—Leveraging General ID Training to Build TID Expertise
ABSTRACT The number of transplant infectious disease (TID) training opportunities has grown over the past decade, and training experiences are heterogeneous. Formal TID fellowships are increasingly ...
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Reposted by Piluca MD
The BMJ @bmj.com · 16/09/2026
Cellulitis is a bacterial infection of the skin and subcutaneous tissue. How is lower limb cellulitis diagnosed, what important differential diagnoses should you consider, and how is it treated? #MedEd bit.ly/4h9norm
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European Centre for Disease Prevention and Control @ecdc.europa.eu · 14/09/2026
Update of the #Ebola virus disease outbreak in DRC - 14 Sep: On 13 Sep, DRC reported a total of 7 200 cases and 3 475 deaths (258 new cases & 126 deaths since the last update). 923 patients remain in isolation. EU/EEA risk assessment remains VERY LOW. More info: bit.ly/ECDCEbolaDRC #IDsky #EpiSky
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Reposted by Piluca MD
Ilan Schwartz @germhuntermd.bsky.social · 13/09/2026
Outcomes After Antifungal Discontinuation in Immunocompromised Patients Treated for Histoplasmosis @nicobarrosid.bsky.social Review of 106 IC pts w histoplasmosis. 28 got <12m Rx (median 182d [123, 217]), 78 got >12m (median 453d [374, 690]). Similar outcomes academic.oup.com/ofid/advance...
KM survival curves comparing treatment duration groups (<12m and >=12m) in histoplasmosis related survival and all cause survival. The lines overlap
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Reposted by Piluca MD
Luis Ostrosky, MD, FIDSA @drluiso.bsky.social · 20/05/2026
We're still #hiring #IDSky www.healthecareers.com/job/id-clini...
healthecareers.com
ID CLINICAL FACULTY POSITION at UTHealth Houston - Jobs in Houston, Texas | Health eCareers
Apply for a ID CLINICAL FACULTY POSITION position at UTHealth Houston in Houston, Texas. Apply today on Health eCareers.
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Reposted by Piluca MD
Ilan Schwartz @germhuntermd.bsky.social · 11/09/2026
Immunotherapy for invasive Candida infections: Translating host-directed strategies into clinical practice www.clinicalmicrobiologyandinfection.org/article/S119...
clinicalmicrobiologyandinfection.org
Immunotherapy for invasive Candida infections: Translating host-directed strategies into clinical practice
Candida infections are a leading cause of invasive fungal disease (IFD), especially among critically ill and immunocompromised patients. Despite available pathogen-directed antifungal therapies, outco...
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Reposted by Piluca MD
Ilan Schwartz @germhuntermd.bsky.social · 11/09/2026
A Scenario-Based Survey of Clinician Recommendations for Follow-up Blood Cultures in Patients with Varying Risk of Persistent Gram-Negative Bacteremia High variability in practice in ordering FU blood cultures in GNB bacteremia Editor’s Choice 🤩 #IDSky academic.oup.com/ofid/advance...
academic.oup.com
Validate User
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ESCMID @escmid.bsky.social · 09/09/2026
🚨 New Epi Alert this week: This week’s Epi Alert highlights continued vector-borne and viral haemorrhagic fever activity across Europe and Africa including updates on West Nile virus, dengue, malaria and the continuing BDBV outbreak. ow.ly/9HJm50Y3Qs0
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Reposted by Piluca MD
Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 09/09/2026
🔥🔥Back online🔥🔥 IDSA/ESCMID 2026 Guidelines on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children Part-1 #idsky www.idsociety.org/practice-gui...
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Clinical Infectious Diseases @cidjournal.bsky.social · 09/09/2026
Histoplasma Capsulatum Antigen Persistence and Rate of Decay During Treatment of Histoplasmosis Varies by Immune Status ✅ Just Accepted 🔗 bit.ly/4hhSE7V
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Reposted by Piluca MD
IDSA @idsainfo.bsky.social · 10/09/2026
Our new Staphylococcus aureus Bacteremia consensus statements (bit.ly/4cBvh7A) give clinicians a roadmap for assessing the severity of infection and how a risk stratification approach can be useful for determining duration of antibiotic therapy. Learn more: bit.ly/46gmHaQ
bit.ly
Staphylococcus aureus Bacteremia
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Sociedad Española de Medicina Tropical y Salud Internacional @semtsi.bsky.social · 11/09/2026
¿Qué eventos adversos experimentan los viajeros durante el viaje? Referencia: Journal of Travel Medicine, 2026, Vol. 33, No. 1, taaf063 doi.org/10.1093/jtm/taaf063 Original Article
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Reposted by Piluca MD
Outbreak News Today @outbreaknews.bsky.social · 12/08/2026
Italy arboviruses: West Nile virus, dengue and chikungunya outbreaknewstoday.substack.com/p/italy-arbo...
outbreaknewstoday.substack.com
Italy arboviruses: West Nile virus, dengue and chikungunya
Since the beginning of the year, as of August 5, 141 confirmed cases of West Nile virus infection in humans have been reported in Italy, of which 64 were neuroinvasive (one case imported from the Mald...
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Reposted by Piluca MD
The Lancet Infectious Diseases @thelancetinfdis.bsky.social · 03/08/2026
New Review A review of Bundibugyo virus and the 2026 outbreak: lessons for epidemic preparedness www.thelancet.com/journals/lan...
thelancet.com
A review of Bundibugyo virus and the 2026 outbreak: lessons for epidemic preparedness
The ongoing 2026 outbreak of Ebola virus disease caused by Bundibugyo virus (BDBV) in the Democratic Republic of the Congo and Uganda has renewed attention to one of the least studied human-pathogenic...
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Reposted by Piluca MD
ESCMID @escmid.bsky.social · 04/07/2026
#ESCMIDSummerSchool26 has now come to a close. As our students and faculty depart for home we send out our thanks for making this edition such a success. We hope you learned a lot, made life-long connections and most of all, had fun! Seeing you next year in Zagreb, Croatia for Summer School 2027 🇭🇷
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Reposted by Piluca MD
ESCMID @escmid.bsky.social · 05/07/2026
📢 ESCMID is seeking an Associate Programme Director for ESCMID Global! This is a unique opportunity to help shape the scientific programme of ESCMID’s flagship congress, working closely with the Programme Director & Executive Committee. 💡 Learn more: ow.ly/ZzJv50ZebVQ #IDSky #clinmicro
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Reposted by Piluca MD
IBiS - Instituto de Biomedicina de Sevilla @ibis-investigacion.bsky.social · 29/06/2026
🔴NEWS | "Un estudio internacional identifica diferencias clave en las infecciones sanguíneas por 𝘊𝘢𝘮𝘱𝘺𝘭𝘰𝘣𝘢𝘤𝘵𝘦𝘳 𝘴𝘱𝘱. según el estado inmunológico de los pacientes" 📎Noticia completa ➡️ www.ibis-sevilla.es/es/noticias/... @unisevilla.us.es @csicandalucia.bsky.social @csicdivulga.bsky.social
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Reposted by Piluca MD
Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 05/06/2026
💥 🔴 Case Report Emergence of Dalbavancin Non-Susceptible Methicillin-Resistant Staphylococcus epidermidis in a Patient Treated With Dalbavancin prolonged therapy despite adequate systemic exposure #idsky www.sciencedirect.com/science/arti...
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Jesús Rodríguez Baño @jesusrbano.bsky.social · 30/05/2026
Bundibugyo ebolavirus outbreak in the Democratic Republic of the Congo and Uganda: rapid assessment from the ESCMID Emerging Infections Subcommittee @cmijournal.bsky.social @escmid.bsky.social www.clinicalmicrobiologyandinfection.org/article/S119...
clinicalmicrobiologyandinfection.org
Bundibugyo ebolavirus outbreak in the Democratic Republic of the Congo and Uganda: rapid assessment from the ESCMID Emerging Infections Subcommittee
The ongoing outbreak of Ebola virus disease (EVD) caused by Bundibugyo ebolavirus (BDBV) in the Democratic Republic of the Congo (DRC) and Uganda represents a major regional public health emergency wi...
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Reposted by Piluca MD
SHORTEN-2 trial @shorten2trial.bsky.social · 23/05/2026
Can we use short treatments for bacteremia in #SOT? This metaanalysis of observational data + SOT randomized in prior trials suggests the efficacy of short courses. We’ve got the rationale to stop excluding SOT from duration trials! onlinelibrary.wiley.com/doi/10.1111/... #IDSky #AMSsky #TxID
onlinelibrary.wiley.com
Outcomes of Short Antibiotic Courses for Gram‐Negative Bloodstream Infections in Solid Organ Transplant Recipients—A Systematic Review and Meta‐Analysis
In this meta-analysis of seven studies involving 249 solid organ transplant (SOT) recipients with Gram-negative bloodstream infections, no statistically significant differences in mortality or clinic....
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Reposted by Piluca MD
SHORTEN-2 trial @shorten2trial.bsky.social · 12/03/2026
Our proposal for managing combination therapy while awaiting for susceptibility in Pseudomonas infections. Find out more: journals.plos.org/plosone/arti... #AMSsky #IDsky #PsWatch
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SHORTEN-2 trial @shorten2trial.bsky.social · 23/05/2026
We’re happy to share that results of the @shorten2trial.bsky.social will be presented at the #XXIXCongresoSEIMC! 📆 Friday, May 29 - 14:25h 📍Room 0D 📻 Stay tuned! #AMSsky #IDSky @absteward.bsky.social @idstewardship.bsky.social @bradspellberg.bsky.social @drtoddlee.bsky.social @esgap.bsky.social
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International Immunocompromised Host Society @ichs-global.bsky.social · 08/05/2026
Celebrating the #ICHS2026 award winners 👏 Honoring excellence in infectious diseases research & care: 🏆 Kontoyiannis 🏆 Kotton 🏆 Mularoni 🏆 Cagno 🏆 Giannella Join us next week May 14–17: ichs.wildapricot.org/Registration...
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CMI Communications @cmicomms.bsky.social · 08/05/2026
Our collaboration episode with Breakpoints covering the trials from the ESCMID Global session 'The trial run' is out now! share.transistor.fm/s/e2a9aee4 🎙️✨ @erinmccreary.bsky.social @gurujosh.bsky.social @jesusrbano.bsky.social #IDSky #clinmicro
share.transistor.fm
Communicable E52: ESCMID Global Trials, PETER PEN and ASTARTE | Communicable | Episode 52
In this collaborative episode of Breakpoints and Communicable, the hosts revisit the “trial run” session from ESCMID Global, a format designed to facilitate critical discussion of major infectious dis...
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Camille Nelson Kotton @kottonnelson.bsky.social · 08/05/2026
I’m running for President of The Transplantation Society to expand global engagement, strengthen transplantation leadership worldwide, and support future leaders. Former TID leader, Executive Committee secretary/councilor, Education co-chair, and CMV/BK guideline developer.
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 08/05/2026
🆕💥🟢Overview of novel cefepime-based β-lactam/β-lactamase inhibitor combinations 🔺Cefepime/enmetazobactam 🔺Cefepime/taniborbactam 🔺Cefepime/zidebactam 🔺Cefepime/nacubactam #idsky www.tandfonline.com/doi/full/10....
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 09/05/2026
🆕💥🟢Non-intravenous Amphotericin B: A Review of Localized Administration Routes 🔺Inhalational 🔺Intrathecal & Intraventricular Routes 🔺Intralesional 🔺Intranasal 🔺Ocular & Periocular 🔺Intravesical 🔺Topical Cutaneous 🔺Amphotericin B-Loaded Bone Cement #idsky link.springer.com/article/10.1...
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 09/05/2026
🆕💥🟢US Enterobacterales (2020–2024):resistance snapshot MBL🔺🔺 Aztreonam-avibactam ++ MDR:20.4%,CRE:1.1%😯,XDR:0.5% ⚠️ Carbapenemase CRE: KPC:~51% MBL:~23% OXA-48:~4% CAZ-AVI & MEM-VAB: ++ non-MBL CRE ATM-AVI + cefiderocol* reliably cover MBL producers #idsky www.sciencedirect.com/science/arti...
sciencedirect.com
Multidrug-Resistant Enterobacterales in United States Hospitals: Frequency and Susceptibility to Newer β-Lactamase Inhibitor Combinations (2020–2024)
Infections caused by multidrug-resistant (MDR) bacteria have increased drastically in the last two decades. We evaluated the activities of newer β-lac…
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 09/05/2026
🆕💥🟢Evaluation of persistence of C. auris colonization When discharged to a non-endemic setting, almost 60% of patients lost C. auris colonization within 5 months after its first detection #idsky www.clinicalmicrobiologyandinfection.org/article/S119...
clinicalmicrobiologyandinfection.org
Evaluation of persistence of C. auris colonization
Colonized patients are the main reservoir of Candidozyma aurisand drive the increase in prevalence of this resistant pathogen. Solid data on duration of long-term persistence of C. auris colonization ...
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 09/05/2026
🆕💥🔴Target trial emulation using a multicenter cohort of critically ill adults with influenza from 48 ICUs Early antifungal prophylaxis did not reduce influenza-associated pulmonary aspergillosis (IAPA) incidence overall #idsky www.clinicalmicrobiologyandinfection.org/article/S119...
clinicalmicrobiologyandinfection.org
Early antifungal prophylaxis fails to prevent influenza-associated pulmonary aspergillosis in the ICU: a target trial emulation
To evaluate whether early antifungal prophylaxis reduces the incidence of influenza-associated pulmonary aspergillosis (IAPA) in critically ill adults with influenza.
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 01/05/2026
Just published 🆕💥🟢Systematic Review and Network Meta-Analysis 20 studies ( 6 RCTs) Beta-Lactam + Azithromycin or Doxycycline Vs Fluoroquinolones in Hospitalized Adult Patients with CAP #idsky #EMIMCC academic.oup.com/ofid/article...
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American Journal of Transplantation @amjtransplant.bsky.social · 30/04/2026
Check out, "Donor-derived blastomycosis," by Gajurel et al in our April issue. www.amjtransplant.org/article/S160... #Transplantation #DonorDerivedInfection #Blastomycosis #TransplantInfectiousDisease
Figure 1 Grocott’s methenamine silver stain (x400 magnification) of lung autopsy showing yeast-like cells consistent with Blastomyces.
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TAGHIVscience @taghivscience.bsky.social · 29/04/2026
Adjunct diagnostic accuracy of antigen-specific interleukin-2 for latent tuberculosis infection in pregnancy academic.oup.com/ofid/advance... (open access) @ofidjournal.bsky.social
academic.oup.com
Adjunct diagnostic accuracy of antigen-specific interleukin-2 for latent tuberculosis infection in pregnancy
Antigen-specific interleukin-2 demonstrates strong diagnostic accuracy for latent tuberculosis infection in pregnancy, comparable to interferon-γ. Combined
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IDSA @idsainfo.bsky.social · 25/04/2026
DYK? Malaria remains a leading cause of preventable illness and death in the world. The global fight against malaria is an ongoing effort, and public awareness is important. Learn more this #WorldMalariaDay: cdc.gov/malaria
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 25/04/2026
SNAP: Cefazolin is non-inferior to Fluclox for MSSA-BSI &causes less AKI Penicillin is non-inferior to Fluclox for PSSA-B Adjunctive clindamycin did not reduce 90-day mortality in SAB Ongoing: Vanco+cefazolin in MRSA BSI Erta/cefaz SAB Early oral switch PET CT #ESCMIDGlobal2026 #idsky
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 23/04/2026
Will LIPS ( Linezoild) RCT be the end of anti toxin antibiotics RCTs in SA Bactremia? Clinda ❌ SNAP Rifampin ❌ ARREST #IDSky
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Steven Tong @steventong.bsky.social · 25/04/2026
It will be published soon. Both the MSSA silo and PSSA silo, which both included (flu)cloxacillin, found NI on 90 day mortality for cefazolin (or penicillin) and lower rates of AKI compared to (flu)cloxacillin. The AKI mostly defined by increase in creatinine of at least 1.5x.
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 20/04/2026
🔥 💥Late-Breakers |COBRA RCT 1-day of antibiotic treatment after adequate endoscopic biliary drainage is non-inferior to 4-7 days in adults with acute cholangitis. 💡 Shorter is better+source control Practice-changing? #ESCMIDGlobal2026 #idsky
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 24/04/2026
"Flu"cloxacillin is out, cefazolin is in. SNAP RCT + CloCeBa RCT Cefazolin is non-inferior to Anti Staphylococcal Penicillins (ASPs) for treatment of MSSA bactremia and causes less AKI and should be 1st line therapy #idsky #ESCMIDGlobal2026
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American Journal of Transplantation @amjtransplant.bsky.social · 30/03/2026
🔓 Open Access "Population-level cancer trends among solid organ transplant recipients in the United States during 1995-2021," by Engels et al is now online & in press! doi.org/10.1016/j.aj... #Transplantation #Oncology #CancerEpidemiology #PopulationHealth #PublicHealth #TransplantOncology
Figure 1 Proportion of the follow-up time among solid organ transplant recipients in the United States during 1995-2021, by calendar year, according to attained age in years (A) or years since first transplant (B).
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ESCMID @escmid.bsky.social · 05/04/2026
The draft document for new ESCMID guidelines is open for comments by ESCMID members. More info can be found on the website by viewing the 'Under public consultation' tab. Request the manuscript and submit your comments before the deadline on 20 April. ow.ly/zGf550YxIWE #IDSky #clinmicro
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 23/03/2026
🔥Just published🔥 SSC 2026 Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 : Critical Care Medicine #IDsky #EMIMCC @pulmcrit.bsky.social share.google/NbagT9xMBTgk...
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Ilan Schwartz @germhuntermd.bsky.social · 17/03/2026
State-of-the-Art Review: Managing Vulvovaginal Candidiasis Riina Rautemaa-Richardson, Jack Sobel, @drneilstone.bsky.social Francesco de Seta, et al, and Elena Roselletti doi.org/10.1093/cid/... #IDSky #MedMycoSky #GynSky @cidjournal.bsky.social
VVC State-of-the-Art visual abstract
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