Hyunah Yoon, MD MS, Liise-anne Pirofski, MD, David R Boulware, MD MPH; Revisiting Immune-Mediated Mechanisms as Drivers of Cryptococcal Immune Reconstituti

Use of some antifungal pesticides may select for resistant fungi in the environment, which can then endanger human health. Coordinated regulatory processes in this area are important.

This cross-sectional study generates a systematic and rigorous estimate of national incident symptomatic coccidioidomycosis cases by developing a model to account for cases missed through national sur...

Abstract. Refractory disseminated coccidioidomycosis (DCM) is a severe disease with limited treatment options. This report reviews our own and prior publis

We conservatively estimated the U.S. economic burden of fungal diseases as $11.5 billion in 2019: direct medical costs ($7.5 billion), productivity loss du

SUMMARYAntibody and antigen detection assays continue to play a significant role in the diagnosis of dimorphic fungal pathogens, including Blastomyces dermatitidis complex, Coccidioides immitis/posada...

Persons with HIV (PWH) are living longer, leading to increased end-organ disease from chronic illness. Organ transplantation improves survival in patients with end-organ disease yet remains a constrai...

Abstract. Histoplasmosis is a life-threatening opportunistic infection in individuals with advanced HIV disease (AHD), particularly in endemic regions such

Background The relationship between asthma and coccidioidomycosis has not been fully described. We have hypothesised that Coccidioides could trigger inflammatory airway responses, similar to other f...

An abstract is unavailable.

Complement and fungal diseases

Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidias...

AbstractBackground. Most histoplasmosis data are from adults. We describe pediatric histoplasmosis diagnosed at a tertiary pediatric care center in an ende

Abstract. Antibiotic prophylaxis for spontaneous bacterial peritonitis (SBPPr) in patients with cirrhosis has been considered standard of care since the 19

T+ and NAT-negative (–) allografts in seronegative recipients. Study Design: All recipients of an HBV core antibody-positive (HBcAb+) LT or KT were prospectively evaluated at a single transplant ce...

This retrospective study evaluating breakthrough invasive mould infections occurring among hematological patients highlights that host factors, including p

Alt: a baby anna from the movie frozen is surrounded by snow

This JAMA Clinical Guidelines Synopsis summarizes the 2024 Society of Critical Care Medicine guidelines on use of corticosteroids in sepsis, acute respiratory distress syndrome, and community-acquired...

This report describes CDC’s updated pneumococcal conjugate vaccine recommendation for all adults aged ≥50 years who are PCV-naïve or who have unknown vaccination history.

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Histoplasmosis was more common among transplant recipients after the first year of transplant. Transplant recipients had more disseminated disease and higher, but not significant mortality at 90 days

Abstract. Histoplasma capsulatum is a pathogenic dimorphic fungus with evolving epidemiology. Initially described as endemic to the Ohio and Mississippi ri

ClinicalTrials.gov; NCT02931539 DATA AVAILABILITY STATEMENT: The datasets, including the redacted study protocol, redacted statistical analysis plan, and individual participants data supporting the re...

This study reports a 4.8% prevalence of T. cruzi infection among 1,523 individuals who required solid organ transplantation from 2019 to 2023, with lung an

The Department of Health and Human Services (HHS) amends the regulations implementing the National Organ Transplant Act of 1984, as amended (NOTA), to remove clinical research and institutional review...

There is an increased risk of infection in patients with cancer that results in higher morbidity and mortality. Several risk factors can predispose these patients to infectious complications. Some suc...

C. auris, a serious public health threat that may have emerged because of climate change, persists on human skin and inanimate objects, frequently causing difficult-to-control outbreaks in health c...

Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...