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Phillip Cleves

@pcleves.bsky.social
1K followers 1K following 16 posts

Symbiosis, cell and developmental biology, and corals. Assistant Professor in Genetics, Genomics, Evolution, and Development at UC-Berkeley.

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Reposted by Phillip Cleves
Ben Parker @ben-parker.bsky.social · 21/09/2026
Excited that our new paper with @henrylabsymbio.bsky.social and Kerry Oliver is out @pnas.org! We show that mobile genetic elements can spread adaptive host-benefiting traits across heritable insect symbionts on eco-evolutionary timescales.🧵 www.pnas.org/doi/10.1073/...
pnas.org
Phenotypic divergence is driven by mobile genetic elements in a heritable insect symbiont | PNAS
Heritable microbes profoundly influence insect biology, yet the traits they confer often evolve rapidly and differ among closely related symbiont s...
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Dmitri Petrov @petrovadmitri.bsky.social · 17/09/2026
We are searching for an Assistant Professor in Evolutionary Biology! Looking for colleagues asking fundamental questions relating to evolutionary processes and drivers of evolutionary patterns. If you think it is you, please do apply! And please repost. facultypositions.stanford.edu/jobs/assista...
facultypositions.stanford.edu
Assistant Professor in Evolutionary Biology - Stanford University, California, United States
The Department of Biology at Stanford University seeks applicants for a tenure-track Assistant Professor in Evolutionary Biology. A successful candidate will conduct research that asks fundamental que...
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George Matsumoto @georgeimatsumoto.bsky.social · 12/09/2026
🧪📍🌊 🦑🍎 @mbarinews.bsky.social invites applications for in-person postdoctoral fellowships in the fields of biological, chemical, and physical oceanography, marine geology, and ocean engineering. Deadline to apply is 5pm PT on December 2, 2026. www.mbari.org/about/career...
mbari.org
Postdoc Fellowships • MBARI
Each year, MBARI invites applications for several in-person postdoctoral fellowships in the fields of biological, chemical, and physical oceanography, marine geology, and ocean engineering. MBARI also...
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Innovative Genomics Institute @innovativegenomics.bsky.social · 27/08/2026
A decade ago, Phil Cleves became the first person to genetically modify #coral. Now, he's trying to figure out how to save reefs and the magnificent ecosystems they host from #ClimateChange. Learn more about IGI's newest investigator: ow.ly/fK9F50ZG9s5 Video by @shumpeim.bsky.social
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Andy Baxevanis @baxevanislab.bsky.social · 20/08/2026
New in Cell: Corals didn't invent a new way to house their algal symbionts — they co-opted an old one. The symbiosome turns out to be built from repurposed lysosomal machinery, with one transporter (SLC26A11) essential for symbiosis. 🪸 @pcleves.bsky.social www.cell.com/cell/fulltex...
cell.com
Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs
Corals harbor intracellular algal symbionts in specialized organelles that enable them to build diverse reef ecosystems. Corals and other cnidarians have repeatedly evolved this symbiosis through the ...
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Reposted by Phillip Cleves
UC Berkeley MCB @berkeleymcb.bsky.social · 14/08/2026
MCB is hiring Assistant Professors across 3 divisions!: 🧪BBS: aprecruit.berkeley.edu/JPF05483 🧬GGED: aprecruit.berkeley.edu/JPF05481 🦠IMM: aprecruit.berkeley.edu/JPF05486 🗓️ Application Deadline: October 19, 2026 🔗 Click the links or scan the QR codes to learn more and apply
MCB is hiring 3 Assistant Professor positions across 3 divisions: 

Biochemistry, Biophysics and Structural Biology (BBS); Genetics, Genomics, Evolution, and Development (GGED); and Immunology and Molecular Medicine (IMM)

BBS application link: https://aprecruit.berkeley.edu/JPF05483

GGED application link: https://aprecruit.berkeley.edu/JPF05481

IMM application link: https://aprecruit.berkeley.edu/JPF05486
Assistant Professor of Immunology and Molecular Medicine (IMM). IMM application link: https://aprecruit.berkeley.edu/JPF05486Assistant Professor of Biochemistry, Biophysics and Structural Biology (BBS). BBS application link: https://aprecruit.berkeley.edu/JPF05483Assistant Professor of Genetics, Genomics, Evolution, and Development (GGED). GGED application link: https://aprecruit.berkeley.edu/JPF05481
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Jonathan Eisen @phylogenomics.bsky.social · 13/08/2026
Job Opening. Faculty Position in Plant Evolutionary Biology at University of California, Davis in the Department of Evolution and Ecology (EVE, my home department). More detail here. recruit.ucdavis.edu/JPF07777
POSITION DESCRIPTION

The College of Biological Sciences at the University of California, Davis invites applications and nominations for a 9-month, tenure-track position in the Department of Evolution and Ecology at the ASSISTANT PROFESSOR level. The Department of Evolution and Ecology is seeking a plant evolutionary biologist with interests in the evolution of plants at any taxonomic, geographic, organizational, or evolutionary scale. Candidates must have a Ph.D. (or equivalent) in the biological sciences, evolutionary biology, ecology, genetics, or a related field, and will be expected to complement and build upon existing faculty strengths in the Department of Evolution and Ecology and across UC Davis.

We welcome applicants working on any group of plants and using empirical, computational, experimental, and/or theoretical approaches. Possible areas of study are broad, and include macroevolutionary research on plant diversification, trait evolution in a phylogenetic context, major evolutionary innovations, comparative genomics, and evolutionary developmental biology, as well as research focusing at or below the species level including population biology, quantitative genetics, adaptive evolution, speciation, biogeography, and the evolution of life histories or species interactions.

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Seth Finnegan @sethf.bsky.social · 11/08/2026
My home department (Integrative Biology, UC Berkeley) is searching for an assistant professor in ecology—please distribute widely! aprecruit.berkeley.edu/JPF05489
aprecruit.berkeley.edu
Assistant Professor –Ecology- Integrative Biology
University of California, Berkeley is hiring. Apply now!
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Holly Moeller @mixotrophe.bsky.social · 07/08/2026
Freaking finally! A massive compilation of data that sat on various desks for almost a decade is finally out. On the positive side, gave me time to learn expansion microscopy and make Fig 1 www.science.org/doi/10.1126/...
science.org
Emergent metabolic parasitism driven by organelle sequestration
Chloroplast-stealing ciliates evolve, increasing reliance on their prey for all aspects of metabolism, including photosynthesis.
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Albert Ruhí @albertruhi.bsky.social · 08/08/2026
We're hiring an ecologist at UC Berkeley! The Dept. of Integrative Biology is hiring a tenure-track Assistant Professor in Ecology. Plants/algae, invertebrates, microbes, or marine systems a priority. Come join us!! Apply by Oct 5, 2026. aprecruit.berkeley.edu/JPF05489 PS: Please share!
aprecruit.berkeley.edu
Assistant Professor –Ecology- Integrative Biology
University of California, Berkeley is hiring. Apply now!
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Inés Fournon Berodia @inesfournon.bsky.social · 04/08/2026
Very pleased to finally share the main story from my PhD, now published in @natcomms.nature.com ! 🎉 Using a sea anemone we discovered and characterised epithelial cell extrusion as the mechanism underlying starvation-induced cell loss. 🔗 Open-access article: www.nature.com/articles/s41...
nature.com
Epithelial cell extrusion underlies starvation-induced cell loss in a sea anemone - Nature Communications
Epithelial cell extrusion in a sea anemone shares key hallmarks with bilaterians and is dynamically regulated by nutritional status. During starvation-induced body shrinkage, extrusion likely contribu...
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Jeff Groh @jeffgroh.bsky.social · 28/07/2026
Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...
pnas.org
Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNAS
In avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm of floral sex timing promotes cross-pollination between two ...
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Jacob Pawley 🧽 🦠 🦕 @pawley.bsky.social · 14/07/2026
A fully updated preprint is now live on @biorxivpreprint.bsky.social :) “Look and see” was a rather important line of thinking regarding freshwater sponge-microbe interactions, centering on the importance of spatial dynamics when evaluating animal microbiomes 🧽🦠🧪 www.biorxiv.org/content/10.6...
Graphical abstract depicting a proposed model of microbial colonization of the skeletal matrix of the freshwater sponge, E. muelleri, during periods of dormancy. This graphic highlights that an epithelium physically separates the host mesohyl from the microbial communities residing within this host-derived external matrix.
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UC Berkeley MCB @berkeleymcb.bsky.social · 02/07/2026
In a new state-of-the-art laboratory, MCB's Phillip Cleves @pcleves.bsky.social and his team are discovering how the symbiotic relationship between algae and corals evolved. news.berkeley.edu/2026/07/01/s...
news.berkeley.edu
Scientists discover how algae colonized corals — a symbiosis that fueled the growth of the world’s reefs - Berkeley News
UC Berkeley biologists uncovered clues to how the symbiosis between algae and corals evolved using a new state-of-the-art lab devoted to year-round genetic experiments on spawning coral.
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Noah Whiteman @nkwhiteman.bsky.social · 25/06/2026
So excited to announce our search for 4 postdocs (funded by the Simons Foundation) who will use genomics to "test how ecological interactions, natural selection, natural enemies, hybridization & environmental gradients shape...tropical tree communities" in Panama: stri.si.edu/story/bci-ev... ...1
stri.si.edu
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Phillip Cleves @pcleves.bsky.social · 02/07/2026
Our work on the symbiont-containing organelle that supports coral reefs is published today. Also, new genetic tools to study symbiosis in both corals and Aiptasia. Great work by Shumpei Maruyama, Cat Henderson, and the rest of the fantastic team. #SymbioSky www.cell.com/cell/abstrac...
cell.com
Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs
Corals harbor intracellular algal symbionts in specialized organelles that enable them to build diverse reef ecosystems. Corals and other cnidarians have repeatedly evolved this symbiosis through the ...
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Reposted by Phillip Cleves
Nancy Moran @nancy-moran.bsky.social · 02/07/2026
A step forward in discovering Buchnera's key to the aphid's heart, published today! Thanks to Jerry Maeda and other authors--a great team -- and to the helpful reviewers #SymbioSky doi: doi.org/10.1038/s415...
doi.org
A secreted endosymbiont protein essential for colonizing host cells - Nature
SyeA was present in the Buchnera ancestor, is secreted into the host cytoplasm, is homologous to secreted effectors of bacterial pathogens and is essential for Buchnera transmission.
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Nat Clarke @natclarke.bsky.social · 01/04/2026
I'm hiring! I have 2 open positions: 🔬 Postdoc 🧪 Research associate We study how animal multicellularity evolved by exploring the molecular logic of cell adhesion using cell biology, 'omics, and tool-building in non-model organisms. Come join us! Details and application links 👇 Please repost
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Parichy Lab | Dave Parichy @dparichy.bsky.social · 30/03/2026
Pleased to announce two new publications, in Current Biology and PNAS, from outstanding postdoc Delai (Dylan) Huang, just a week before he leaves to start his new faculty position at Zhejiang University.
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Pawel Burkhardt @pawelburkhardt.bsky.social · 04/03/2026
Even more excited — our paper is featured on the cover of Science Advances! Huge thanks to @alexandrejan.bsky.social who took this incredible photo of a ctenophore (aka comb jelly) and the editors. Here’s the cover 👇 www.science.org/doi/10.1126/...
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Phillip Cleves @pcleves.bsky.social · 02/03/2026
To increase the use of gene editing in corals, we have made a comprehensive methods paper describing the protocol. We hope this helps the field of functional genetics in corals. www.nature.com/articles/s41...
nature.com
Efficient genome editing using CRISPR–Cas9 in reef-building corals - Nature Protocols
In this protocol, the authors present straightforward and efficient methods to genetically modify corals and study gene function throughout various life-history stages using CRISPR–Cas9-based mutagene...
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Anyi Mazo-Vargas @anyimv.bsky.social · 27/02/2026
🦋✂️🧬 🧪 New preprint! Led by @donyaniyaz.bsky.social CRISPR‑Cas9 knockouts of ABCG transporters across butterflies & moths reveal how pigment pathways shape color during development. #CRISPR #Lepidoptera #pigmentation Feedback welcome 👩‍🔬 www.biorxiv.org/content/10.6...
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Phillip Cleves @pcleves.bsky.social · 26/02/2026
It is happening again! Consider taking our course on the Molecular and Cell Biology of Symbiosis at @mblscience.bsky.social. Application deadline March 4th! www.mbl.edu/education/ad...
mbl.edu
Molecular and Cell Biology of Symbiosis | Marine Biological Laboratory
This is an immersive research-based course designed to teach basic concepts, open research questions, and facilitate state-of-the-art experimental approaches in symbiosis research.
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John Wallingford @jbwallingford.bsky.social · 10/02/2026
Registration is OPEN for the 2026 Santa Cruz Meeting on Developmental Biology!!! Please spread the word! @mads100tist.bsky.social @socdevbio.bsky.social @bsdb.bsky.social @xenbase.bsky.social @isdb.bsky.social @devbiol.bsky.social @the-node.bsky.social scdb2026.sites.ucsc.edu
scdb2026.sites.ucsc.edu
Santa Cruz Developmental Biology Meeting
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Daniel Bolnick @danielbolnick.bsky.social · 05/02/2026
New preprint from our big collaborative evolution experiment in 9 whole lakes in Alaska, written by McGill grad student @lucaseckert.bsky.social www.biorxiv.org/content/10.6... What happens if you put a mixture of multiple source populations together to complete & evolve in multiple new lakes?
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Genetics Society of America @genetics-gsa.bsky.social · 29/12/2025
New #GENETICS report from @pcleves.bsky.social et al. shows the use of a simple electroporation protocol to introduce various genetic constructs into Aiptasia zygotes, a small sea anemone and an emerging model to study coral biology. buff.ly/5aQpQ1S
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John Wallingford @jbwallingford.bsky.social · 19/12/2025
The 2026 Santa Cruz Developmental Biology Meeting website is LIVE!!! Go see the incredible list of scientists who will be speaking at the meeting next summer! (...and check the site early next year for info on registration and abstract submission.) scdb2026.sites.ucsc.edu
scdb2026.sites.ucsc.edu
Santa Cruz Developmental Biology Meeting
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Phillip Cleves @pcleves.bsky.social · 16/12/2025
Beautiful work. www.biorxiv.org/content/10.6...
biorxiv.org
Epithelial cell extrusion underlies starvation-induced cell loss in a sea anemone
Epithelia likely predate the last common animal ancestor, yet the evolutionary origin and environmental regulation of epithelial remodelling remain poorly understood. Here, we show that extensive, sta...
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Phillip Cleves @pcleves.bsky.social · 22/10/2025
www.pnas.org/doi/abs/10.1...
pnas.org
An endosymbiotic origin of the crimson pigment from the lac insect | PNAS
Symbioses with microorganisms expand the genetic and metabolic repertoire of many insects. The lac insect Kerria lacca (Hemiptera: Sternorrhyncha) ...
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Phillip Cleves @pcleves.bsky.social · 13/10/2025
New paper from the lab. Molecular characterization of the symbiont-containing organelle with proteomics and reverse genetics in Aiptasia and coral.
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Arnau Sebé-Pedrós @arnausebe.bsky.social · 24/09/2025
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life. www.nature.com/articles/s41...
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Vesna Grujcic @vesnagrujcic.bsky.social · 30/08/2025
How do microbes become permanent partners? 🌊🔬🦠 Check out our new study published in Current Biology showing how cyanobacterial genomes evolve step-by-step into endosymbionts of diatoms. www.sciencedirect.com/science/arti... @currentbiology.bsky.social @mehrshmali.bsky.social
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Emily Yeager @emilyyeager9.bsky.social · 21/08/2025
Before today, I would have never known it was possible to run DNA extractions and PCR without a lab. Who knew that a molecular bio bento box could facilitate bringing the lab into the field? I’m very excited to see how our hornwort Cyanobacteria community sequencing turns out later this week.
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UC Berkeley MCB @berkeleymcb.bsky.social · 20/08/2025
We're Hiring! Assistant Professor of Immunology and Molecular Medicine in MCB. Learn more and apply online: aprecruit.berkeley.edu/JPF05096
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Nature @nature.com · 31/07/2025
This surprisingly relaxing footage is from SIX MILES under the ocean – and it’s the deepest ecosystem yet discovered
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Nature Portfolio @natureportfolio.nature.com · 26/05/2025
A paper in Nature reports the discovery of fossilized claw prints thought to belong to an amniote on a slab of rock from Australia dated to about 356 million years ago, suggesting that the origin of amniotes is earlier than expected. go.nature.com/4jm5XTP #Paleosky 🧪
This is figure 3, which shows amniote footprints.
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Phillip Cleves @pcleves.bsky.social · 02/04/2025
It is happening again! Consider taking our course on the Molecular and Cell Biology of Symbiosis at @MBLScience. We extended the deadline for applications to Apr 14, 2025. www.mbl.edu/education/ad...
mbl.edu
Molecular and Cell Biology of Symbiosis | Marine Biological Laboratory
This is an immersive research-based course designed to teach basic concepts, open research questions, and facilitate state-of-the-art experimental approaches in symbiosis research.
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Emily Meier @emilykmeier.bsky.social · 28/03/2025
It’s live! Check out the Cleves Lab website and learn how the lab uses ecologically relevant cnidarian models to gain key insights into how microbial symbiosis and its breakdown impact animal biology and health, driving new coral conservation efforts. 🪸🎉 @pcleves.bsky.social www.cleveslab.org
cleveslab.org
The Cleves Lab
The Cleves Lab researches the molecular, cellular, and developmental basis of how intracellular beneficial microbes invade and persist in animal cells to form symbiosis. They use ecologically critical...
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The Symbiosis Courses Alumni Network @symbiosisalumni.bsky.social · 05/02/2025
Save the date 📅: The PhD Summer School on Host-microbe Symbioses is taking place from 6-19 of July in Oeiras, Portugal. Registration is opening soon! Learn more 👉 gimm.idloom.events/phd-summer-s... @gimmfoundation.bsky.social @moorefound.bsky.social @crc1182.bsky.social #CIFAR #CBR
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Fabien Burki @fburki.bsky.social · 21/01/2025
#protistsonsky
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Roberto Mayor Lab @mayorlab.bsky.social · 11/12/2024
Neural crest of Xenopus embryos labelled with nuclear GFP
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Darrin Hunt @benthicbuddy.bsky.social · 06/12/2024
Lets put this back in the feed and see if there is anyone else who who'd like to be added. We are getting your future grad students ready, and plan on writing a book one day…maybe. go.bsky.app/RnHK313
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Steve Haddock @stevehaddock.bsky.social · 02/12/2024
A video we made at @mbarinews.bsky.social explaining some functions of #fluorescence in the ocean, and how #bioluminescence is different… but related. 🦑🧪🌊 m.youtube.com/watch?v=whbe...
m.youtube.com
The allure of fluorescence in the ocean
YouTube video by MBARI (Monterey Bay Aquarium Research Institute)
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Thomas P200 Burke @findmeinthelab.bsky.social · 02/12/2024
I'm pumped to finally share our lab's first publication! Microbiology and cancer are deeply intertwined, and this is our first foray into the cancer field. We asked: how do bacteria activate innate immunity in tumors to elicit anti-cancer responses? www.sciencedirect.com/science/arti...
sciencedirect.com
Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies
Intracellular bacterial pathogens are distinctive tools for fighting cancer, as they can proliferate in tumors and deliver therapeutic payloads to the…
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Moita Lab @moitalab.bsky.social · 02/12/2024
Thrilled to present our latest BioRXiv on brain/body interactions during defensive freezing behaviour! (www.biorxiv.org/content/10.1...). You might think that a frozen animal has, well, frozen muscle activity, right? Wrong! Underneath the still surface of a fly, something in the legs is beating… 🧵
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Pablo J. Sáez @pjsaez.bsky.social · 01/12/2024
Last week I showed to MSc students this iconic movie of a #leukocyte chasing a #bacteria, just wait... Version taken from a 16 mm video made by David Elliot Rogers @VanderbiltU in the 1950s ! (as @mag2art.bsky.social says "the Citizen Kane of #Microscopy) #CellMigration @focalplane.bsky.social
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Daniel Ibrahim @danielibrahim.bsky.social · 28/11/2024
🔺🔺🔺RED TRIANGLE ALERT 🔺🔺🔺 Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!! Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals! SMCs & RNA-Pol are the only thing they have in common www.nature.com/articles/s41...
nature.com
Evolution and function of chromatin domains across the tree of life - Nature Structural & Molecular Biology
Szalay et al. discuss cross-kingdom similarities and differences in 3D chromatin folding in relation to gene regulation, including in bacteria, archaea, mammals and plants. This comparison reveals cer...
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Fabien Burki @fburki.bsky.social · 28/11/2024
nature.com/articles/s41... #protistsonsky
nature.com
The Acrasis kona genome and developmental transcriptomes reveal deep origins of eukaryotic multicellular pathways - Nature Communications
Acrasis kona is a solitary amoeba which builds a multicellular fruiting body, despite being a distant relative of other multicellular eukaryotes. This study analysed A. kona’s genome and developmental...
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 12/11/2024
I still love this figure. Submitting revisions this week. SNPs in transcription factor binding sites (green) explain the majority of additive genetic variation for >70% of ~150 phenotypes (rows) in maize. See Alt for detailed figure legend. See www.biorxiv.org/content/10.1... for more!
Estimated additive genetic variance organized by 143 traits. Colored ridges show the estimated additive genetic variance across 100 permutations for either MOA bQTL (green), bgSNPs (orange), and remaining genome SNPs (purple). Black symbols represent the mean estimated value across permutations. Traits arranged by bQTL mean variance estimates and color coded according to general trait groupings: vitamin E metabolites = navy blue, metabolites = purple, stalk strength = light blue, flowering time = gold, plant architecture = red, disease = green, tassel architecture = pink, ear architecture = orange, misc. = grey.
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Patrick Steinmetz @prhsteinmetz.bsky.social · 12/11/2024
Join us at the Symbiosis course! With @pcleves.bsky.social @scottnichols.bsky.social & others!
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