Sign in

Paul Hoskisson 🧫 🦠🐸

@paulhoskisson.bsky.social
4.6K followers 3.8K following 393 posts

Professor of Molecular Microbiology, Fellow of the Royal Society of Edinburgh, Editor at Microbial Genomics & mBio, Scouse, interested in Streptomyces, Evolution, Antibiotics, AMR, microbiology, Phage, herpetology, Cricket, EvertonFC

PostsRepliesMedia
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 09/10/2026
Thanks @mermanchester.bsky.social for hosting me,such a great day of science, thanks @bexlowrypalms.bsky.social @matthewjshepherd.bsky.social for the invitation,great to catch up @whelanfj.bsky.social @alanmcn1.bsky.social @drrebeccajhall.bsky.social @mbottery.bsky.social @brockhurstlab.bsky.social
0123
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 09/10/2026
Brilliant #postdoc opportunity on the role of gut microbiomes in bird thermal resilience #HOTGUT project at Lund University (Dept. of Biology)! Supervisor is the awesome @kruthsatz.bsky.social , Andreas Nord as co-supervisor. Please repost Apply here: lu.varbi.com/what:job/job...
lu.varbi.com
Postdoktor inom ekoevolutionär mikrobiomforskning och termobiologi
Ämnesbeskrivning Tjänsten är en del av forskningsprojektet “From Guts to Growth: Unravelling the Gut Microbiome’s Role in Ontogenetic Trajectories toward Climate Stress Resilience” (HOTGUT).
0613
Reposted by Paul Hoskisson 🧫 🦠🐸
Gemma Murray @gemmamurray.bsky.social · 04/09/2026
I’m hiring two postdocs to join my group at UCL, both funded for 3 years, to investigate how commensal bacteria contribute to the evolution and spread of antimicrobial resistance in pathogens. Please share! Links below 👇 www.jobs.ac.uk/job/DSU266/r... www.jobs.ac.uk/job/DSU268/r...
01828
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 08/10/2026
Great to see you too, and thank you!
000
Reposted by Paul Hoskisson 🧫 🦠🐸
Rebecca Lowry Palmer @bexlowrypalms.bsky.social · 08/10/2026
Fantastic talk today from @paulhoskisson.bsky.social at our UoM Ecology and Evolution Seminar - all about Streptomyces evolution and antibiotic production! 🧬🦠 Such cool work!
184
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 08/10/2026
Off to University of Manchester and excited to talk to members of @mermanchester.bsky.social, give a seminar, and catch up with friends, collaborators and new people to meet up and discover more about the cool science they do
1133
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 08/10/2026
really cool work from @lore-fermar.bsky.social et al Differential restructuring of a complex compost microbiome by metabolically distinct #Streptomyces through community-dependent microbial interactions eprints.gla.ac.uk/396050/1/396...
eprints.gla.ac.uk
052
Reposted by Paul Hoskisson 🧫 🦠🐸
Danna Gifford @dannagifford.bsky.social · 06/10/2026
📣 New preprint: We looked at population survival and recovery of the thermophilic archaeon Sulfolobus acidocaldarius at near-boiling temperatures—conditions that occur in its environmental niche. www.biorxiv.org/content/10.6...
biorxiv.org
074
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 07/10/2026
this is such a cool paper - Microbial community dynamics in a traditional Swiss mountain cheese over 142 years of cheesemaking www.cell.com/current-biol...
cell.com
Microbial community dynamics in a traditional Swiss mountain cheese over 142 years of cheesemaking
How did modernizing cheesemaking change the microbes inside the cheese? By sequencing preserved traditional Alpine cheese wheels spanning 142 years from a single Alpine dairy, Somerville et al. trace ...
1184
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 06/10/2026
super cool from the @peterfineran.bsky.social et al Defining the essential genome of diverse phages with phage Tn-seq www.nature.com/articles/s41...
nature.com
Defining the essential genome of diverse phages with phage Tn-seq - Nature Microbiology
Phage Tn-seq uses Tn5 transposon mutagenesis with anti-CRISPR-based selection and deep sequencing as a method to generate unbiased, genome-wide mutations across diverse phages
0138
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 25/09/2026
And another one www.biorxiv.org/content/10.6...
biorxiv.org
TeTIR domains define a new class of animal TIR-like NADase effectors in STAND proteins
TIR domains are found in diverse immune signaling proteins and, in several systems, function as NAD+-cleaving enzymes causing or signaling cell death. In plants, TIR domains occur as effector domains ...
010
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 24/09/2026
Not read this in detail yet…but looks interesting and thought provoking….will it help or add fuel to fires on discussions around lab releases of organisms? Language-Model-Based Detection of Genetic Editing in Bacteria www.biorxiv.org/content/10.6...
biorxiv.org
Language-Model-Based Detection of Genetic Editing in Bacteria
Recent advances in genome editing allow easy genetic manipulation of bacteria, providing them with new traits, some of which could be hazardous, e.g. enhanced virulence or extended resistance to antib...
222
Reposted by Paul Hoskisson 🧫 🦠🐸
FishEvo Zuzana Musilova @fishevo.bsky.social · 22/09/2026
Hot off the preprint: visual adaptations in crater-lake #cichlids revealed by single-cell RNA-seq of the retina. Deep-water species have mainly green cones that however differ from both green and red cones of the shallow-water species. Quite unexpected in such young adaptive radiation!😍
13810
Reposted by Paul Hoskisson 🧫 🦠🐸
Richard Lenski @relenski.bsky.social · 22/09/2026
"Philosophy of Biology: The power of theory in the life sciences" elifesciences.org/articles/112... @zdblount.bsky.social shared this thought-provoking paper with the lab group.
elifesciences.org
Philosophy of Biology: The power of theory in the life sciences
Theory can help address cell and molecular biology’s major challenges, particularly those arising from large omics datasets.
110346
Reposted by Paul Hoskisson 🧫 🦠🐸
Rosemary Mosco @rosemarymosco.com · 22/09/2026
Happy mushroom season!
A comic titled "Types of mushrooms" with 12 mushroom species. A wrinkly-looking morel is labeled "creepy but tasty". A brownish deadly galerina is labeled "boring but deadly". A witch's butter on a branch is labeled "jiggles if you poke it". A large puffball is labeled "egg". A creepy red-dripping bleeding tooth fungus is labeled "deeply disconcerting". A fly agaric with a green treefrog sitting under it is labeled "frog umbrella". A black chanterelle is labeled "chalice for forbidden elixers". Three straight-stemmed entolomas are labeled "haha, nipples". A bright purple viscid violet cort is labeled "purple is nice". A birch polypore sticking out of a birch trunk is labeled "tree nose". A complex yellow-tpped coral fungus is labeled "cursed citadel where dwells a fairy queen". A Ravenel's stinkhorn is pixellated at the top for your safety, and labeled "NSFW".
5140621327
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 22/09/2026
This is very cool @kelleygallagher.bsky.social et al Regulatory divergence and functional diversification of a c-di-GMP-controlled sigma factor in Actinomycetota doi.org/10.1128/msys...
doi.org
Regulatory divergence and functional diversification of a c-di-GMP-controlled sigma factor in Actinomycetota | mSystems
Mounting global responses to dynamic environmental conditions is a crucial function that bacterial cells must perform. Global regulatory networks are most often studied in individual species, however,...
0105
Reposted by Paul Hoskisson 🧫 🦠🐸
Artologica aka Michele Banks @artologica.net · 14/09/2026
Attention #sciart people! The ASM agar art contest is open. Deadline is October 21 🧪🧫
asm.org
ASM Agar Art Contest | Contest Details
Have you ever seen art created in a petri dish using living, growing microorganisms? That's agar art! ASM's annual Agar Art Contest is a chance for you to use science to show off your creative skills.
210347
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 13/09/2026
The bird that changed Ecuador: how a chance discovery of a rare species helped to save many more www.theguardian.com/environment/...
theguardian.com
The bird that changed Ecuador: how a chance discovery of a rare species helped to save many more
Thirty years after a US ornithologist first sighted a jocotoco antpitta, the foundation he set up to restore biodiversity is a model for conservation globally
022
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 13/09/2026
Fascinating stuff - Acquisition and erosion of toxin-antitoxin systems in bacterial chromosomes academic.oup.com/mbe/advance-...
academic.oup.com
Acquisition and erosion of toxin-antitoxin systems in bacterial chromosomes
Abstract. Toxin-antitoxin systems (TAs) are widespread in bacterial genomes. Yet, their integration, persistence, and impact in chromosome dynamics remain
04620
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 11/09/2026
Sent! All good here, hope you guys are well? Must catch up soon! X
010
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 11/09/2026
Really important from @ellinoralseth.bsky.social & @brownlab.bsky.social - a framework for defense as an evolved adaptation, in a world where ‘defense’ & ‘immune’ are often used to mean anti-infection The bacterial immune system: identifying evolved defense adaptations www.cell.com/trends/micro...
cell.com
The bacterial immune system: identifying evolved defense adaptations
Recent years have witnessed a rapid expansion in bacterial defense mechanisms. Alongside established defenses against molecular parasites, hundreds of novel mechanisms are being described annually, co...
12011
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 09/09/2026
Wow, this is getting fascinating with these NADases - seems pretty widespread - three BioRxivs on this exciting antiviral system in a matter of months from the Ibarra-Chavez lab www.biorxiv.org/content/10.6... and Tagliabracci lab www.biorxiv.org/content/10.6...
biorxiv.org
Antimicrobial-resistance plasmids encode Evangelion, a widespread DUF4062 anti-phage defence family
Many bacterial anti-phage defence systems are encoded by mobile genetic elements, yet much of this antiviral repertoire remains undiscovered. Antimicrobial-resistance plasmids are well known for disse...
1144
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 07/09/2026
Great collection in Essays Biochem on the social lives of bacteria - put together by @friendlymicrobe.bsky.social & @rachelwheatley.bsky.social doi.org/10.1042/EBC2... happy to contribute with ‘Colony politics to chemical warfare: phenotypic plasticity in #Streptomyces’ doi.org/10.1042/EBC20250034
portlandpress.com
A special issue of Essays in Biochemistry on the social lives of bacteria
Abstract. The study of bacterial sociality, understanding when and how bacteria interact and the consequences of those interactions, has rapidly grown in popularity over the last 20 years. This has re...
064
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 25/08/2026
you drunk? haha - always a pleasure matey
020
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 25/08/2026
Super collection of essays here in ‘Essays in Biochemistry’ @biochemsoc.bsky.social focussed on Bacterial Biosynthetic Gene Clusters - lots of interesting perspectives portlandpress.com/essaysbioche... all pulled together by @evodivmet.bsky.social
portlandpress.com
Volume 70 Issue 2 | Essays in Biochemistry | Portland Press
Essays in Biochemistry publishes short, digestible reviews from experts highlighting recent key topics in biochemistry and the molecular biosciences. Written to be accessible for those not yet immerse...
031
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 25/08/2026
Can I apply? 🫣😂 sounds very cool!
010
Reposted by Paul Hoskisson 🧫 🦠🐸
Kathryn R Elmer @profkathrynelmer.bsky.social · 25/08/2026
We have a ca 1.5 yr postdoc available in our team, asking, 'what is the shape of the fitness landscape between oviparity and viviparity?' and 'what drives viviparity to evolve'? 🧬 using 🦎 as a model. closes 16 Sept. Details on EvolDir evoldir.net/brian/evoldi... @glasgow.ac.uk @sbohvm.gla.ac.uk
11316
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 25/08/2026
This is super cool from @ecoevoevoeco.bsky.social & @danielbolnick.bsky.social et al Eco-Evolutionary Dynamics of Infection and Immunity in Experimentally Founded Lake Populations of Threespine Stickleback www.journals.uchicago.edu/doi/10.1086/...
journals.uchicago.edu
Eco-Evolutionary Dynamics of Infection and Immunity in Experimentally Founded Lake Populations of Threespine Stickleback | The American Naturalist: Vol 208, No 3
AbstractHost-parasite interactions are likely to involve eco-evolutionary feedbacks. Parasites can impose strong selection on host immune traits. Evolution of these traits can suppress parasite abunda...
041
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 24/08/2026
Really cool paper from @sheppardlab.bsky.social et al Accelerating Campylobacter zoonosis in the Anthropocene www.pnas.org/doi/10.1073/... - and I was delighted to be invited to write a commentary about this lovely work too www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
001
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 20/08/2026
awww sorry Kathryn! its super work….fascinating stuff!
100
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 20/08/2026
A bacterial metabolite rewires fungal metabolism, triggering the hyphae-to-yeast transition www.cell.com/current-biol...
cell.com
A bacterial metabolite rewires fungal metabolism, triggering the hyphae-to-yeast transition
The hyphae-to-yeast morphological transition promotes dissemination of the pathogen Candida albicans, but the mechanisms underlying this process are poorly defined. By identifying a bacterial metaboli...
0124
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 20/08/2026
Beautiful work from @profkathrynelmer.bsky.social et al Genome-wide barriers to gene flow reveal the genetic basis of viviparity evolution in a lizard www.cell.com/current-biol...
cell.com
Genome-wide barriers to gene flow reveal the genetic basis of viviparity evolution in a lizard
Xie et al. resolve the complex and dynamic evolutionary history of viviparity emergence in an amniote, the common lizard. They demonstrate a key involvement of gene regulatory regions, found genome wi...
141
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 11/08/2026
We should plan a day at the cricket next season!
100
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 11/08/2026
🤣 - in proper Cricket, Lancs beat Somerset in Taunton, which is unheard of!
100
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 04/08/2026
All good matey, been a crazy busy time…see you in October, or hopefully before if you’re up this way?
100
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 04/08/2026
Thanks Mark!
010
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 04/08/2026
Thanks Melanie! Hope you’re well? P
010
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 04/08/2026
Thanks matey!
110
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 04/08/2026
Happy birthday to you too @drgvank.bsky.social - hope you’ve had a good day? P x
250
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 02/08/2026
They are so wonderful
000
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 02/08/2026
Couple of gorgeous Adders (Vipera berus) from this mornings walk - always a joy to see these
Adder
180
Reposted by Paul Hoskisson 🧫 🦠🐸
Shu-Sin Chng @figlegend.bsky.social · 05/07/2026
Intense week of science at Bacterial Cell Surfaces GRC! Best part was catching up with old/new friends! Tagging peeps in pics @paulhoskisson.bsky.social @hendersonlab.bsky.social @namurxa.bsky.social @sujeetkumar.bsky.social @weeboont.bsky.social @yeowjiang.bsky.social @siegristpalmore.bsky.social
0181
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 01/07/2026
really lovely piece of work from @raufs.bsky.social et al., Complex multicellularity is linked with expanded specialized metabolite production in microorganisms www.nature.com/articles/s41...
nature.com
Complex multicellularity is linked with expanded specialized metabolite production in microorganisms - Nature Microbiology
The evolutionary emergence of complex multicellularity in bacteria and fungi, such as the ability for mycelial growth, is strongly associated with increased genomic carriage of biosynthetic machinery ...
042
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 30/06/2026
this is very cool - Chemical ecology and convergent evolution of natural hallucinogens: From ecological defense to conserved neural targets www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
092
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 29/06/2026
Cool new preprint of a new defence family! Antimicrobial-resistance plasmids encode Evangelion, a widespread DUF4062 anti-phage defence family www.biorxiv.org/content/10.6...
biorxiv.org
Antimicrobial-resistance plasmids encode Evangelion, a widespread DUF4062 anti-phage defence family
Many bacterial anti-phage defence systems are encoded by mobile genetic elements, yet much of this antiviral repertoire remains undiscovered. Antimicrobial-resistance plasmids are well known for disse...
1218
Reposted by Paul Hoskisson 🧫 🦠🐸
George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 23/06/2026
Our Dept of Microbiology & Immunology @Geisel School of Medicine @Dartmouth has an opening for an Assistant Professor. Looking for programs bridging multiple areas in Micro & Immuno. A great place to be! Programs: www.M2P2.org www.dartmouthbiofilm.org Job ad: apply.interfolio.com/187637
16387
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 23/06/2026
First ‘Charles Darwin’ Rose of the year has opened in the garden!
1110
Reposted by Paul Hoskisson 🧫 🦠🐸
Royal Society Publishing @royalsocietypublishing.org · 23/06/2026
New research from #BiologyLetters: Song but not colour divergence constrains hybridization in birds doi.org/10.1098/rsbl... | #Evolution #Birdsong #Colouration
0147
Reposted by Paul Hoskisson 🧫 🦠🐸
Royal Society Publishing @royalsocietypublishing.org · 15/06/2026
A type of natural selection known as negative frequency dependent selection is thought to be a major force promoting genetic diversity in important traits. Read research in a new issue of #PhilTransB: buff.ly/bOhpNlE
1106
Reposted by Paul Hoskisson 🧫 🦠🐸
Russ Jones @russincheshire.bsky.social · 22/06/2026
In the future, everybody will be Prime Minister for 15 minutes — Andy Narwhal
915117