The outer membrane (OM) of Gram-negative bacteria serves as an effective permeability barrier and confers intrinsic antibiotic resistance. This barrier function requires distinct distribution of lipid...

Mycolic acids (MAs) are the major component of the mycobacterial outer membrane, a key contributor to the intrinsic resistance of mycobacteria to e...

Nature Communications - The asymmetric distribution of lipopolysaccharide (LPS) on the surface of the bacterial outer membrane is essential and crucial for antibiotic resistance. Here, authors...

Gram-negative bacteria assemble an asymmetric outer membrane (OM) that functions as an effective barrier against antibiotics. Building a stable and functional OM requires the assembly and maintenance ...

The Gram-negative bacterial cell envelope comprises an outer membrane (OM) with an asymmetric arrangement of lipopolysaccharides (LPS) and phospholipids (PLs), protecting them from both physical and c...

Partitioning of FtsN and the septal peptidoglycan synthesis complex between an active synthesis track and an inactive denuded glycan track coordinates opposing peptidoglycan synthesis and degradation ...

The Tol-Pal complex is important for multiple cellular processes in Gram-negative bacteria, but its molecular functions remain unclear. Here, Tan & Chng provide experimental evidence supporting th...