Sign in

Dr. Natalie Clark

@nmclark2.bsky.social
1.1K followers 1.7K following 58 posts

Computational Scientist in the Proteomics Platform at the Broad Institute. Systems biologist integrating ALL the omics data. Views are my own. She/her.

PostsRepliesMedia
Reposted by Dr. Natalie Clark
Ben Neely @benneely.com · 24/02/2026
Were you at #USHUPO2026 and saw Ben @proteomicsnews.bsky.social and Renã Robinson with Natalie Clark @nmclark2.bsky.social for a LIVE recording of #THEProteomicsShow? Well, I wasn't either, but we now we can bathe our ears in this audio. Find it wherever you find podcasts. anchor.fm/theproteomic...
2103
Reposted by Dr. Natalie Clark
Frank Cvetkovic (from comics) @gofrankgo.bsky.social · 29/10/2025
Back in my day, AI used to stand for Adobe Illustrator! And we hated that, too!
Grandpa Simpson yelling at a cloud
73180895268
Reposted by Dr. Natalie Clark
Science Magazine @science.org · 09/10/2025
President Donald Trump’s administration has terminated $352 million in grants and contracts this year to the Research Triangle Institute, the United States’s third largest independent research organization, a report estimates.
science.org
Cuts in global health and climate hit Research Triangle Institute hard
“Financial drubbing” underscores reliance of some independent research organizations on federal funding
25031
Reposted by Dr. Natalie Clark
North American Arabidopsis Steering Committee @naascarabidopsis.bsky.social · 22/09/2025
Please share & RSVP to join the November 25th webinar! Hear from the 2025 Philip N. Benfey Arabidopsis Community Lifetime Achievement Awardees! bit.ly/naascawards @plantevolution.bsky.social
12422
Reposted by Dr. Natalie Clark
Universal Hub @universalhub.com · 04/09/2025
Healey: Massachusetts insurers have to cover the cost of all vaccines approved by the state, no matter what the brainworm in chief says. This includes MassHealth and GIC.
13731181
Reposted by Dr. Natalie Clark
Stephen Turner @stephenturner.us · 25/08/2025
Regulatory network topology and the genetic architecture of gene expression www.biorxiv.org/content/10.1... 🧬🖥️🧪
073
Dr. Natalie Clark @nmclark2.bsky.social · 01/08/2025
Proud to share our collaborative effort between the Taiwan Cancer Moonshot Program and the NCI’s Clinical Proteomic Tumor Analysis Consortium (CPTAC), delivering an integrative proteogenomic atlas of lung adenocarcinoma. Open-access link: authors.elsevier.com/sd/article/S...
authors.elsevier.com
ScienceDirect.com | Science, health and medical journals, full text articles and books.
360
Dr. Natalie Clark @nmclark2.bsky.social · 26/06/2025
Movie you've watched more than 6x using a gif (no Disney, Star Wars, LOTR, or Star Trek).
media.tenor.com
a man wearing a helmet is giving the middle finger in front of a sign that says 440
ALT: a man wearing a helmet is giving the middle finger in front of a sign that says 440
640
Reposted by Dr. Natalie Clark
Margot Smit @likeyoda1.bsky.social · 05/06/2025
We're looking for a new PhD candidate to join the lab. Please share 🌱😄
A PhD position (initially 3 years) is available in our laboratory in the Center for Plant Molecular Biology (ZMBP), at the University of Tübingen (Germany). The position is available with an intended start date starting January 2026.
Interested applicants should submit a single PDF comprising a motivation letter describing your research interests, an up-to-date CV, and the names and contact information for 2 references to timing.lab@zmbp.uni-tuebingen.de ideally before July 21st.
383125
Reposted by Dr. Natalie Clark
DisabledInSTEM @disabledinstem.bsky.social · 29/04/2025
Here's a database from UCLA on Non-NIH funding opportunities ranging from grad students to faculty from a wide range of biological and medical disciplines: biofund.healthsciences.ucla.edu/crt-funding/...
biofund.healthsciences.ucla.edu
BioFund - a Non-NIH Funding Database | crt-funding
23427
Reposted by Dr. Natalie Clark
ProteomicsNews (Ben Orsburn) @proteomicsnews.bsky.social · 20/03/2025
HEY PROTEOMICS PEOPLE! Can you comment here where you learned to do proteomics? I started putting up a survey but based on just the 64 people on our podcast there are too many options for a multiple choice survey effectively. Thank you!
49115
Reposted by Dr. Natalie Clark
Randall Munroe @xkcd.com · 17/03/2025
Lungfish xkcd.com/3064
95118511304
Reposted by Dr. Natalie Clark
Mark Peifer (He, him) @peiferlabunc.bsky.social · 11/03/2025
Awesome to see my good friend & amazing scientist Jeff Dangl share with Jonathan Jones and Brian Staskawicz the 2025 Wolf Prize in Agriculture for their pioneering work on plant disease resistance 🧪1/n wolffund.org.il/jeffery-l-da...
Pictures of the three laureates
“For groundbreaking discoveries of the immune system and disease resistance in plants.”:
Jeffery Dangl, Jonathan Jones, and Brian Staskawicz, Wolf Prize Laureates in Agriculture 2025, have revolutionized our understanding of plant immunity and disease resistance.
Celebrate their transformative work in shaping sustainable agriculture!
@TheSainsburyLab
 
@PMB_Berkeley
 
@UNC_Biology
 
@HHMINEWS
 
#wolfprize2025
#wolfprizelaureate #wp2025laureate #wp2025agriculture #wp202
14111
Dr. Natalie Clark @nmclark2.bsky.social · 10/03/2025
Can someone please explain to my 11 month old that we lost an hour so he should sleep an hour later, not get up an hour earlier? In other news, this is my annual complaint about DST. I'm so tired 😴
020
Reposted by Dr. Natalie Clark
Kevin Collins @kwcollins.bsky.social · 07/03/2025
My daughter's daycare just sent out an email about potentially needing to layoff staff because new babies about to start withdrew because of parental job losses. So if you're wondering how government layoffs and mass contract cancellations will affect the economy, here's an example
241156263964
Reposted by Dr. Natalie Clark
Frank Hochholdinger @hochholdingerf.bsky.social · 07/03/2025
Travel permits of all US government employees (USDA, NSF) have been revoked shortly before the the maize meeting affecting: - The chair of the meeting - The winner of the most prestigious McClintock award - A plenary speaker - Two short talk presenters - 22 scientists presenting posters. #MGM2025
First slide of the maize meeting.
67146
Dr. Natalie Clark @nmclark2.bsky.social · 02/03/2025
NIH websites are down because of a DNS attack. They are working on it. Via reddit.
012
Dr. Natalie Clark @nmclark2.bsky.social · 23/02/2025
Just arrived for #USHUPO2025! Excited to give a talk at the #CPTAC workshop Monday evening. Feel free to reach out directly if you'd like to chat about multi-omics analysis!
060
Reposted by Dr. Natalie Clark
Ryan Flynn @raflynn5.bsky.social · 18/02/2025
congrats to Brendan Floyd, postdoc in @carolynbertozzi.bskyverified.social lab on his exciting work "mapping the nanoscale organization of the human cell surface proteome" High resolution, High Effort, and Creative Analytics produce new views of the cell surface www.biorxiv.org/content/10.1...
0327
Reposted by Dr. Natalie Clark
PlantEvolution 🌱🌾 @plantevolution.bsky.social · 15/02/2025
To US colleagues who have lost or are in imminent danger of losing their jobs: please DM whether we can accommodate your research.
German and US flags
3308134
Reposted by Dr. Natalie Clark
Laura Alder, MD @lauraaldermd.bsky.social · 22/11/2024
Honored to be interviewed about the rising incidence of lung cancer in non-smokers and especially females on @wral.bsky.social to shed light on #LCSM during #LungCancerAwarenessMonth and highlight the #HearHer campaign www.wral.com/lifestyle/he... @younglungcancer.bsky.social
wral.com
Rising lung cancer cases in nonsmoking women under 50: Experts urge awareness
An unexpected surge in lung cancer cases among nonsmoking women under 50 is raising alarms among oncologists, emphasizing the need for heightened awareness.
1197
Reposted by Dr. Natalie Clark
Justin Walley @justinwwalley.bsky.social · 21/11/2024
Our Arabidizzle ubiquitinome paper is published! Awesome collaboration w @diorkelley.bsky.social lab lead by Gaoyuan Song - key contributions from so many others (@dormichicken.bsky.social @nmclark2.bsky.social) @theplantcell.bsky.social #proteomics #PlantScience academic.oup.com/plcell/advan...
academic.oup.com
Quantitative proteomics reveals extensive lysine ubiquitination and transcription factor stability states in Arabidopsis
An antibody-based approach to enrich ubiquitinated peptides reveals Arabidopsis root, seedling, and leaf ubiquitinomes.
54526
Reposted by Dr. Natalie Clark
The Lewis Lab @peterlewislab.bsky.social · 19/11/2024
"Dark TFs": new manuscript mapped 166 uncharacterized human transcription factors, finding half bind genomic "dark matter," often closed chromatin rich in transposable elements. www.biorxiv.org/content/10.1...
320059
Reposted by Dr. Natalie Clark
Gen Wojcik @genandgenes.bsky.social · 19/11/2024
There is a whole crop of us who lost our minds trying to ramp up careers while handling ever-changing childcare arrangements. Our family went ~ two years without a solid month of scheduled childcare. It has taken so much time & energy to recover, w/the loss of productivity still being felt.
vox.com
The parents of the youngest children are not okay
An epidemiologist on the health risks of the omicron variant, child care issues, and the unique pandemic struggles of working parents.
3309
Reposted by Dr. Natalie Clark
Gabriele Corso @gcorso.bsky.social · 17/11/2024
To read more about Boltz-1 check out: - Our short blog-post jclinic.mit.edu/boltz-1/ - Our technical report: gcorso.github.io/assets/boltz... - Our code, model and instructions: github.com/jwohlwend/bo... I'll share a separate thread with more details about the process and interesting findings!
jclinic.mit.edu
Introducing Boltz-1: Democratizing Biomolecular Interaction Modeling – MIT Jameel Clinic
3448
Reposted by Dr. Natalie Clark
Alex Toker @alextoker.bsky.social · 17/11/2024
Great to be posting science again!! Very proud of this work, thanks to a wonderful collaboration with Forest White lab at MIT, Cantley lab at DFCI, and leb by the amazingly talented @alissandra-hillis.bsky.social! Published as fully @openaccess.bsky.social in PNAS. www.pnas.org/doi/10.1073/...
17716
Reposted by Dr. Natalie Clark
Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 12/11/2023
A few years old, but worth a read (perhaps in particular to those who do ML in BIO or take biological databases for granted) 🧪🧬🖥️ "How Margaret Dayhoff Brought Modern Computing to Biology" www.smithsonianmag.com/science-natu...
smithsonianmag.com
How Margaret Dayhoff Brought Modern Computing to Biology
The pioneer of bioinformatics modeled Earth’s primordial atmosphere with Carl Sagan and made a vast protein database still used today
13016
Reposted by Dr. Natalie Clark
John Prensner @johnprensner.bsky.social · 16/11/2024
Here is a paper where I would just like to say "Thank you" to the authors. I thoroughly enjoyed this. I hope you do too. #GENESky #RNAsky #CANsky #genomics #bioinformatics 🧪 🧬💻 🔎 microproteins www.cell.com/cell-reports...
cell.com
RNA splicing junction landscape reveals abundant tumor-specific transcripts in human cancer
Li et al. thoroughly analyzed RNA splicing junctions in 34,775 samples and identified 29,051 tumor-specific transcripts that may serve as cancer driver genes, neoantigens, and circulating biomarkers.
14212
Reposted by Dr. Natalie Clark
PlantEvolution 🌱🌾 @plantevolution.bsky.social · 13/11/2024
Watch Joanne's call to arms for plant scientists to fight climate change: www.ted.com/talks/joanne... #plantscience
ted.com
How supercharged plants could slow climate change
Plants are amazing machines -- for millions of years, they've taken carbon dioxide out of the air and stored it underground, keeping a crucial check on the global climate. Plant geneticist Joanne Chor...
39632
Reposted by Dr. Natalie Clark
PlantEvolution 🌱🌾 @plantevolution.bsky.social · 13/11/2024
The Salk Institute shared the sad news that Prof. Joanne Chory passed away yesterday due to complications from Parkinson’s disease. She was one of the most influential biologists of our time. And this is how I will remember Joanne, expertly guiding us on where to go. Joanne, we will miss you! ❤️
Two people on a punting boat
1122467
Reposted by Dr. Natalie Clark
Chanda Prescod-Weinstein 🌌 @chanda.blacksky.app · 11/11/2024
Given that Trump’s numbers didn’t grow significantly and a bunch of people who voted for Biden stayed home for Harris, now is the time to think about why! And I join other Black feminists in not believing that it’s all interpersonal racism toward Kamala. Lots of factors to think through.
3423
Dr. Natalie Clark @nmclark2.bsky.social · 11/11/2024
Introduction time! I am Natalie Clark, currently a Computational Scientist in the Proteomics Platform at the Broad Institute of MIT and Harvard. I previously was a hybrid wet-lab/computational scientist performing large-scale transcriptomic and proteomics experiments in Arabidopsis and corn. (1/2)
1112
Reposted by Dr. Natalie Clark
Alejandro Brenes @ajbrenes.com · 10/11/2024
#teamMassSpec here is a starting pack in case you just moved over, or in case you've been absent for a while. This is #proteomics or #massspec related. The pack is not comprehensive but it's a start. go.bsky.app/HH7kqEh
198751
Reposted by Dr. Natalie Clark
Justin Walley @justinwwalley.bsky.social · 10/11/2024
Final version of or single-cell proteomics paper is now published in the New Phytologist December issue! @dormichicken.bsky.social nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com
Single‐cell proteomics differentiates Arabidopsis root cell types
See also the Commentary on this article by van Schie & Weijers, 244: 1678–1680.
24312
Reposted by Dr. Natalie Clark
Scott McGrath @smcgrath.phd · 08/11/2024
🧪 AI advances in protein design are transforming structure generation and folding predictions, but challenges in reliability and function remain. Researchers aim to refine protein binders and enzymes for practical use. 🧬🖥️ #MLSky
nature.com
Five protein-design questions that still challenge AI
Tools such as Rosetta and AlphaFold have redefined the protein-engineering landscape. But some problems remain out of reach — for now.
0177
Dr. Natalie Clark @nmclark2.bsky.social · 09/11/2024
Hello blue sky, I've officially left Twitter behind! Looking forward to reconnecting with everyone over here 🙂
0120