iiinova — where your digital self keeps evolving

Reposted by Nikolas Stefanidis

Seán Doran @theseaning.bsky.social · 25/09/2026

Wow!

Reposted by Nikolas Stefanidis

Nicolas Di-Poi @nicolasdipoi.bsky.social · 22/09/2026

Our collaborative paper on snake coiling is now out in the latest issue of @currentbiology.bsky.social and featured on the cover! 🎉 Delighted to see our work highlighted this way. You can read it here: authors.elsevier.com/c/1ni9h3QW8S... @helsinki-biotech.bsky.social @helsinki.fi

15918

Reposted by Nikolas Stefanidis

British Antarctic Survey 🐧 @bas.ac.uk · 18/09/2026

Shhh, try not to disturb this sleeping crabeater seal as you pass. She's a rare first visitor for Bird Island Research Station (a sub-Antarctic island). They normally prefer pack ice near the Antarctic continent and rarely travel this far north! Girl, that's a big journey. Let 👏 her 👏 nap 👏

A dozing crabeater seal, photographed by Katherine Thomas who is a seal scientist at Bird Island Research Station

16712

Reposted by Nikolas Stefanidis

The HPS Podcast @hpspodcast.bsky.social · 11/09/2026

"But on the night sky, it's like seeing an atom held at arm's length..." This week on the podcast, Peter Galison joins Sophie Ritson to discuss what it took to make the first image of the black hole — and what it means to say we saw it. linktr.ee/thehpspodcast

14224

Reposted by Nikolas Stefanidis

Nicolas Di-Poi @nicolasdipoi.bsky.social · 31/08/2026

And with a nice coverage of our study in Science @science.org ! 🐍🌀 More on the developmental mechanics behind snake coiling here: doi.org/10.1126/scie...

doi.org

Snake embryos often coil in one direction. Now, we may know why

Mismatch between growth of body and digestive system bends the body, study suggests

0172

Reposted by Nikolas Stefanidis

Hourly Cosmos @hourlycosmos.bsky.social · 31/08/2026

The Magnificent Neptunian System - From Rolf Wahl Olsen - flic.kr/p/nix1x1

014331

Reposted by Nikolas Stefanidis

James Briscoe @jamesbriscoe.bsky.social · 27/08/2026

Our latest: We develop a dynamical landscape modelling framework based on time resolved single-cell data Applied to neural tube fate decisions it shows cell fate decisions as flip bifurcations, a circular topology & it predicts unseen signalling regimes @plosbiology.org doi.org/10.1371/jour...

doi.org

Dynamic Landscape Analysis of cell fate decisions provides predictive models of neural development from single-cell data

Applying dynamical systems theory to single-cell data can provide a detailed picture of the cellular states observed during cell fate decisions. This study presents a dynamic landscape analysis (DLA) ...

25619

Reposted by Nikolas Stefanidis

Cells & Development @cellsdev.bsky.social · 20/08/2026

Less is more!

0246

Reposted by Nikolas Stefanidis

Philip Ball @philipcball.bsky.social · 10/08/2026

"The central challenge is no longer building models that reproduce biological behavior, but building models from which causal structure can be inferred." Very sensible paper about not just throwing everything into your simulation or model. arxiv.org/abs/2608.06998

arxiv.org

Simulating is not always understanding: When model complexity obscures biology

In cell biology, computational models of biological systems range from minimal representations with a handful of parameters to whole-cell simulations tracking thousands of molecular species across a c...

911734

Reposted by Nikolas Stefanidis

Benjamin Swedlund @benswedlund.bsky.social · 27/07/2026

Check out my first preprint highlight with @prelights.bsky.social! How cells read the room - coordinated symmetry breaking and proportional cell fate allocation in neural organoids, from Hannah T Stuart et al. Lovely story with solid back-and-forth between modelling and perturbative experiments.

prelights.biologists.com

Minimal essential requirements for neural tube self-organisation - preLights

How cells read the room - coordinated symmetry breaking and proportional cell fate allocation in neural organoids

0225

Reposted by Nikolas Stefanidis

Matt Towers @matt-towers.bsky.social · 02/07/2026

Pleased to share our latest! We show that the chick limb can be directed to recapitulate key stages in mammalian evolution, providing a unifying model for digit patterning across amniotes. Preprint: www.biorxiv.org/content/10.6... Video summary: www.youtube.com/watch?v=fvL_...

biorxiv.org

Transforming avian to mammalian modes of digit patterning

How a conserved embryonic organiser-the Sonic hedgehog (Shh)-expressing Zone of Polarising Activity (ZPA)-generates diverse limb architectures in amniotes remains a central problem in evolutionary and...

12511

Reposted by Nikolas Stefanidis

Guillaume Jacquemet @guijacquemet.bsky.social · 30/06/2026

Delighted to share our latest preprint "NucleiSky enables cross-scale multimodal registration of microscopy data using nuclei constellations" www.biorxiv.org/content/10.6... Code and App: github.com/CellMigratio...

37436

Reposted by Nikolas Stefanidis

Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 29/06/2026

1/ 🧬🔬 How does one cell become an entire animal? We can now film it in 3D 🐟, but turning those movies into accurate cell tracks is brutally hard. Enter our new #Kaggle challenge: $60K prize pool, to help crack 3D+time cell tracking at scale! 🧵👇 www.kaggle.com/competitions... @biohub.org

17941

Reposted by Nikolas Stefanidis

Seán Doran @theseaning.bsky.social · 26/06/2026

'Night Ride' 2,744 images from 3 time-lapse sequences photographed by Nicole Mann, Josh Casada & Koichi Wakata on Expedition 68 are repaired, remastered and interpolated to create this real time video footage with ambient audio from ISS recorded by Chris Hadfield. 45m42s 4K youtu.be/rF-OjTgJwVc

youtu.be

ISS - Night Ride · 4K

YouTube video by Seán Doran

0178

Reposted by Nikolas Stefanidis

Landru79 @landru79.bsky.social · 27/06/2026

#CASSINI ORBITER #SATURN MISSION Target: #Janus #Titan Time: 2006-03-21 Camera: Narrow Angle Clear Filter opus.pds-rings.seti.org/opus/#/COISS... NASA/JPL/j. Roger

24519

Reposted by Nikolas Stefanidis

allen institute @alleninstitute.org · 26/06/2026

New in @natmethods.nature.com: a new human stem cell model of EMT lets us watch cells transition in both 2D and 3D and shows human stem cells can undergo the transition differently depending on how they are grown. 🔗 doi.org/10.1038/s41592-026-03096-9

03011

Reposted by Nikolas Stefanidis

Brandy A Freitas @brandy-syglass.bsky.social · 25/06/2026

🔬 For #3DThursday: a whole cleared mouse embryo imaged with DALISPIM from @lifecanvastech.bsky.social A theme from #FOM2026 + #ELMI2026 was that light microscopy innovation can come from rethinking imaging geometries, in this case an open-top inverted #lightsheet. 🎬: #syGlass v2.6.0

2134

Reposted by Nikolas Stefanidis

Riding With Robots @ridingrobots.bsky.social · 25/06/2026

From NASA Photo finish! 🏁📸 On June 14, Perseverance completed a Martian “marathon” by surpassing 26.2 miles (42.195 kilometers) of travel. The day before, NASA’s Mars Reconnaissance Orbiter snapped this view of the rover and its tracks from space.

An area west of Jezero Crater, Mars, as captured by the HiRISE instrument aboard NASA's Mars Reconnaissance Orbiter on June 13, 2026. The terrain consists of a desert landscape with small hills and fields of dunes.

The car-sized Perseverance rover is visible as a small, bright, blue-green dot, circled in yellow. The rover's tracks are also visible as a thin gray line winding through the terrain.

NASA/JPL-Caltech/UArizona

38624

Reposted by Nikolas Stefanidis

epithelial mechanics fan club @epimechfc.bsky.social · 25/06/2026

Brooks, E. R., & Wallingford, J. B. (2014). Multiciliated cells. Current biology, 24(19), R973-R982. #EpithelialMechanicsReview doi.org/10.1016/j.cu...

041

Reposted by Nikolas Stefanidis

Oxford Mathematics @oxfordmathematics.bsky.social · 21/06/2026

One day I saw one cow dressed in a uniform. A vital piece of mathematical learning. Depending where you live, that is. The Tower of Babel - Episode 4

062

Reposted by Nikolas Stefanidis

Society for Developmental Biology @socdevbio.bsky.social · 19/06/2026

⭐️ A stony coral, Montipora capitata, primary polyps, one month of age. Autofluorescence of symbiotic algae (magenta) and GFP (green). 🔬 📸 Credit: Emma Rangel-Huerta from Stowers Institute for Medical Research #FluorescenceFriday #devbio #cnidarians 🪸

04013

Reposted by Nikolas Stefanidis

Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · 17/06/2026

Today we welcome Professor Jenny Nichols (University of Edinburgh), who will talk about her work on early mammalian development. Host: Stan Strawbridge @stanleystrawbridge.bsky.social All welcome!

082

Nikolas Stefanidis @nikolasstefanidis.bsky.social · 16/06/2026

Very pleased with the outcome of presenting our work published on BioRxiv (see below) at BioInference 2026 in St Andrews. Even happier about meeting peers with a background in biology who made the jump to computational modelling. 🫂 @yaricerruti.bsky.social thanks for the snap! 📷

130

Reposted by Nikolas Stefanidis

Daniel Pomarède @pomarede.bsky.social · 15/06/2026

Astronomy Picture of the Day Triple Shockwave from Sun Crossing Rocket Credit: John Winkopp for WAI media apod.nasa.gov/apod/ap26061... More amazing pics by J. Winkopp at www.spacecoastpictures.com 🧪🔭

$A photography featuring the passage of a rocket in front of the Sun, capturing multiple shockwave structures. Explanation: What's happening to this Sun-crossing rocket? The SpaceX Falcon 9 rocket, visible on the upper left, launched only about one minute before this amazing image was captured. As it rose to low Earth orbit from Cape Canaveral, Florida, USA, in late May, the rocket became supersonic before it crossed the disk of the distant Sun -- from the perspective of the well-placed photographer. The spacecraft's high speed caused bow-shaped compressed-air shockwaves to form across leading surfaces, with at least three visible even outside the Sun's disk because they refract sunlight. The trailing exhaust caused turbulence visible on the lower right. None of this was damaging to the robotic Starlink 10-53 mission, which delivered 29 communications satellites to low Earth orbit as planned. And if that isn't amazing enough - the Sun had spots! Credit text: APOD$

213335

Reposted by Nikolas Stefanidis

Daniel Gorelick @danielgorelick.bsky.social · 03/06/2026

Paying peer reviewers works. Expanded Fast & Fair experiment @biologyopen.bsky.social: • 5.5 vs 37.7 working days to decision with reviews • ~3 vs ~9 reviewer invitations per manuscript • no reduction in editor-assessed review quality • similar acceptance rates www.biorxiv.org/content/10.6...

Scatter plot showing that Fast & Fair peer review reached first decision with reviews much faster than conventional peer review: mean 5.5 versus 37.7 working days. Most Fast & Fair manuscripts met the 7-working-day target, while conventional manuscripts were slower and more variable, up to 116 working days.

8232117

Reposted by Nikolas Stefanidis

Dave Barry @david-j-barry.bsky.social · 01/06/2026

In the latest issue of @jcellsci.bsky.social, with @lankylaste.bsky.social, Lina Gerontogianni and Gavin Kelly at @crick.ac.uk, a reanalysis of images from the IDR to answer the age-old question: How do you tell statistical significance from biological significance? doi.org/10.1242/jcs....

1139

Reposted by Nikolas Stefanidis

Benjamin Swedlund @benswedlund.bsky.social · 27/05/2026

I’m super excited to announce that the work from my postdoc is now openly available on BioRxiv!! A novel reaction-diffusion architecture for engineering self-organized patterns in mammalian cells, from @leonardomorsut.bsky.social lab and friends (1/9) www.biorxiv.org/content/10.6...

3175

Nikolas Stefanidis @nikolasstefanidis.bsky.social · 21/05/2026

Always a pleasure to present at @pintofscience.uk🍺🧠 This time about the intricacies of our second brain (enteric nervous system), how it develops 🧩 and how systems biology helps us learn more 🖥️🧮 #pintofscience #phd #systemsbiology

132

Reposted by Nikolas Stefanidis

Céline Imagénieuse @celineimagenieuse.bsky.social · 15/05/2026

Notre Bel ESM 😍🤩

1145

Reposted by Nikolas Stefanidis

Daniel Pomarède @pomarede.bsky.social · 08/05/2026

As if you were there: Return to Earth with the Artemis II crew www.youtube.com/watch?v=37Hx... #Artemis

youtube.com

As if you were there: Return to Earth with the Artemis II crew

YouTube video by Canadian Space Agency

1103

Reposted by Nikolas Stefanidis

Gareth Moore @garethmoore.bsky.social · 30/04/2026

Over the moon to see this work from my PhD finally published in Development! Using a combination of structural biology and genetics we identify an avidity-driven mechanism of BMP signal control in the extracellular space. (1/11)

33510

Nikolas Stefanidis @nikolasstefanidis.bsky.social · 30/04/2026

⚛️🎙️Check out my chat with @sudeuyulgan.bsky.social on her Lab voices series that you can find on her IG @phdlifewithsude. We discussed about making the jump from a tech post to a PhD and making the bigger jump from wet lab to systems biology. #PhDSky #SystemsBiology

031

Reposted by Nikolas Stefanidis

British Society for Cell Biology @bscb-official.bsky.social · 23/04/2026

Fantastic talk from our 2026 Postdoc ECR Medal Winner @giuliapaci.bsky.social from @lmcb-ucl.bsky.social at #DynamicCellVI explaining her research on the role of 3D epithelial topology in developmental patterning Congratulations Giulia 👏👏

0248

Reposted by Nikolas Stefanidis

Digital Brain @yourdigitalbrain.bsky.social · 17/04/2026

Witness breathtaking drone footage capturing the fiery heart of a volcanic eruption. A new era of vulcanology is here, revealing nature's power like never before.

902234385

Reposted by Nikolas Stefanidis

Sude Uyulgan @sudeuyulgan.bsky.social · 17/04/2026

How do you build the posterior end of a body? 🧫🔬🧬 I am excited to share that my PhD work on the generation of hindlimb and genital progenitors from human pluripotent stem cells is now available on BioRxiv! 🔗 www.biorxiv.org/content/10.6...

biorxiv.org

2104

Reposted by Nikolas Stefanidis

Daniel Pomarède @pomarede.bsky.social · 14/04/2026

Orion and solar eclipse: new, fascinating image posted on NASA Johnson's flickr account, captured by a GoPro camera mounted on one of the Orion spacecraft’s solar array wings. Venus can be spotted on the left, and Saturn on the right of the Moon. flic.kr/p/2s7wkRo #Artemis 🧪🔭

The solar eclipse captured from a camera mounted on one of the Orion spacecraft’s solar array wings during the Artemis II crew’s flyby of the Moon’s far side. The science community is investigating whether the glow around the Moon is from zodiacal light -- interstellar dust that’s reflecting sunlight -- the solar corona, or a combination of the two. Unlike minutes-long eclipses as viewed from Earth, the Artemis II crew saw the Sun hide behind the Moon for nearly an hour. In this image, Venus can be spotted on the left, and Saturn on the right of the Moon. Credit: NASA

215145

Reposted by Nikolas Stefanidis

Eric Peterman @errricpeterman.bsky.social · 10/04/2026

Happy #fluorescencefriday (and start of vacation!) to all those who are celebrating Lifeact-labeled epidermal stem cells closing a wound after in vivo adult zebrafish skin injury

413435

Reposted by Nikolas Stefanidis

Daniel Pomarède @pomarede.bsky.social · 11/04/2026

Hero spacecraft inside the well deck of the USS John P. Murtha www.flickr.com/photos/nasah... #Artemis 🧪🔭

NASA’s Orion spacecraft is seen as the agency’s Landing and Recovery team, along with U.S. Navy personnel work to recover the spacecraft into the well deck of USS John P. Murtha in the Pacific Ocean off the coast of California, Saturday, April 11, 2026. NASA’s Artemis II mission, which took NASA astronauts Reid Wiseman, commander; Victor Glover, pilot; Christina Koch, mission specialist; and CSA (Canadian Space Agency) astronaut Jeremy Hansen, mission specialist on a nearly 10-day journey around the Moon and back to Earth, splashed down at 5:07 p.m. PDT (8:07 p.m. EDT). Photo Credit: (NASA/Joel Kowsky)

49124

Reposted by Nikolas Stefanidis

Daniel Pomarède @pomarede.bsky.social · 10/04/2026

How it started, how it's going Left: Lunar Orbiter I, 1966 Right: Artemis II, 2026 flic.kr/p/8Grtp2 flic.kr/p/2s68RXM #Artemis 🧪🔭

The world's first view of Earth taken by a spacecraft from the vicinity of the Moon. The photo was transmitted to Earth by the United States Lunar Orbiter I and received at the NASA tracking station at Robledo De Chavela near Madrid, Spain. This crescent of the Earth was photographed August 23, 1966 at 16:35 GMT when the spacecraft was on its 16th orbit and just about to pass behind the Moon. Credit: NASA.

Earthset captured through the Orion spacecraft window at 6:41 p.m. EDT, April 6, 2026, during the Artemis II crew’s flyby of the Moon. A muted blue Earth with bright white clouds sets behind the cratered lunar surface. The dark portion of Earth is experiencing nighttime. On Earth’s day side, swirling clouds are visible over the Australia and Oceania region. In the foreground, Ohm crater has terraced edges and a flat floor interrupted by central peaks—formed when the surface rebounded upward during the impact that created the crater. Image Credit: NASA.

520768

Reposted by Nikolas Stefanidis

Daniel Pomarède @pomarede.bsky.social · 10/04/2026

Artemis II Lunar Flyby gallery www.nasa.gov/gallery/luna... #Artemis 🧪🔭

NASA’s Orion spacecraft captures the Moon and the Earth in one frame during the Artemis II crew’s deep space journey at 6:42 p.m. ET on the sixth day of the mission. The right side of NASA’s Orion spacecraft is seen lit up by the Sun. A waxing crescent Moon is visible behind it. And then, a crescent Earth, tiny compared to the Moon, is about to set below the Moon’s horizon on the right. Credit: NASA

The Moon, seen here backlit by the Sun during a solar eclipse on April 6, 2026, is photographed by one of the cameras on the Orion spacecraft’s solar array wings. Orion is visible in the foreground on the left. Earth is reflecting sunlight at the left edge of the Moon, which is slightly brighter than the rest of the disk. The bright spot visible just below the Moon’s bottom right edge is Saturn. Beyond that, the bright spot at the right edge of the image is Mars. Credit: NASA

As the Artemis II crew flew over the terminator, the astronauts described this boundary between day and night as "anything but a straight line." Crater rims along the terminator stand out as "islands" in the night. Giant chains of craters emanating from the 3.7-billion-year-old Orientale basin can be seen scouring the surface, stretching almost to the terminator. This tells a geologic story: these crater chains produced by the Orientale impact event mar the surface of the relatively flat Hertzsprung Basin (center of this image), which means that Hertzsprung Basin must be even older than Orientale!

Image Credit: NASA

05619

Reposted by Nikolas Stefanidis

Daniel Pomarède @pomarede.bsky.social · 05/04/2026

Peering out one of the four windows near the display console of the Orion spacecraft, the Earth is illuminated by the blackness of space and grows smaller as the crew journeys closer to the Moon. Credit: NASA. flic.kr/p/2s5Vzbd #Artemis 🧪🔭

A crescent Earth far away in the darkness with the frame of a window of the Orion Integrity spacecraft to the left. This image was taken by an Artemis II crew member on the fifth day of the mission, using a Nikon D5 camera.

0437

Reposted by Nikolas Stefanidis

allen institute @alleninstitute.org · 13/03/2026

Our #CellLineOfTheWeek is beta-actin - illuminating actin filaments! 🧫 Our entire catalog of stem cell lines & plasmids are available to researchers for just the cost of shipping to reduce the barriers to discovery 📦 Distributed by @Coriell_Science and @Addgene

083

Reposted by Nikolas Stefanidis

Alex Eve @amjeve.uk · 10/03/2026

Many animals adjust or pause development in response to environmental conditions to maximise survival. To understand this potential, called diapause, @bulutkarslioglu.bsky.social induces a diapause-like state in mice & embryonic stem cells. #gfe2026 @dev-journal.bsky.social interview with Aydan⤵️

doi.org

Transitions in development – an interview with Aydan Bulut-Karslioglu

Aydan Bulut-Karslioglu is a Group Leader at the Max Planck Institute for Molecular Genetics, Germany, where her research focuses on the epigenetic and metabolic mechanisms regulating embryonic develop...

1114