Felix Ehret, David R Raleigh; All roads lead to ROAM: A look at the results of the ROAM/EORTC-1308 clinical trial, Neuro-Oncology, , noag234, https://doi.o

AbstractBackground. Pediatric diffuse midline gliomas (pDMG) are lethal tumors, with approximately 80% harboring a lysine-to-methionine mutation in histone

Tumour network mapping of diffuse midline glioma (DMG) defines a conserved and prognostically important brain network in children with DMG, consistent with the hypothesis that DMGs exploit otherw...

Experts in Heidelberg have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system ide...

Longitudinal transcriptomic, chromatin and genomic analyses of the two types of IDH-mutant glioma reveal in detail how disease progression is influenced by interdependent genetic, epigenetic and micro...

The conference program will aim to highlight the constant evolution throughout life of the developmental, immune and neuronal contexts of brain tumors The thematic sessions will seek to establish lin...

Organoids provide a useful model to capture the heterogeneity of brain tumours. Here, the authors assess current methodologies for generating organoids from various types of brain tumour and discuss h...

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AbstractAbstract. BackgroundThe oncological role of resection in elderly patients with glioblastoma remains controversial. We evaluated the value of resect

Daniel Kirschenbaum from the German Cancer Research Center (DKFZ) is developing new methods to find out exactly how immune cells are suppressed by malignant brain tumors. He is being supported in this...

AbstractBackground. Scarce T cell infiltration, immunosuppressive tumor-associated macrophages and ineffective drug delivery drive glioma progression and l

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Glioblastomas initially respond to radiotherapy but invariably recur, often within high-dose radiation treatment fields. Although stromal radiation responses are incompletely understood, evidence sugg...

Watch The Brain Prize webinars on Cancer Neuroscience featuring leading experts sharing advanced research on cancer–nervous system interactions.

The proposed RANO classification for extent of resection could serve as a tool for prognostic stratification. Although associations between survival and extensive surgery are evident sooner in patient...

An early clinical study demonstrates feasibility of noninvasive 5-ALA sonodynamic treatment in nine patients with recurrent high-grade glioma.

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OverviewThe Fueling Cancer Progression by the Nervous System series will feature six webinars, each exploring the junction between neuroscience and cancer biology to advance our understanding of cance...