Experts in Heidelberg have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system ide...

Sill and colleagues present an expanded DNA methylation classifier for CNS tumors. Building upon the 2021 WHO classification, this resource introduces a hierarchical taxonomy of 184 subclasses. It enhances classification accuracy for rare entities and provides integrated genomic data from a single, streamlined assay for modern neuro-oncology.

Inspirierender Austausch mit Parlamentarier:innen zum Innovationscampus Health + Life Science Alliance Heidelberg I Mannheim Unter dem Motto "Zukunft Innovationsstandort Baden-Württemberg: Life Scienc...

Application of a nanopore sequencing workflow for real-time analysis of brain tumors results in molecular classification within a 30-minute intraoperative window, followed by comprehensive profiling w...

Application of a nanopore sequencing workflow for real-time analysis of brain tumors results in molecular classification within a 30-minute intraoperative window, followed by comprehensive profiling w...

The North Sea's historical migrations have impacted the genetic structure of its neighbouring populations. We analysed haplotype sharing among 858,635 modern individuals from Denmark and Britain to in...

Abstract. Genome-wide DNA methylation signatures correlate with and distinguish central nervous system (CNS) tumor types. Since the publication of the init

IDH-mutant astrocytomas are diffuse gliomas that are defined by characteristic mutations in IDH1 or IDH2 and do not have complete 1p/19q co-deletion. The established grading criteria include histologi...

Vaccination in glioblastomas does lead to the emergence of tumour-antigen-specific T cells but T cell dysfunction, poor tumour infiltration and persistence hinder efficient tumour killing. Here author...