Abstract. Episodic memory retrieval relies on encoding-pattern reinstatement (EPR), the reactivation of neural representations formed during encoding. Alth

By exploiting Drosophila to study glial regulation of synapse development and maintenance across the lifespan and performing an in vivo genetic screen, Jay et al. reveal new molecular pathways require...

Using unbiased whole-brain activity mapping in mice, the authors looked for circuits that previous adversity remodels to heighten sensitivity to later stress.

Fat is an essential nutrient. Learn why it's so important for your brain, the best types to eat, and where to find them in your diet.

APOE4 causes a pericyte-to-myofibroblast transition that promotes cerebrovascular fibrosis and perivascular amyloid accumulation. TGF-β inhibition reverses this pathological remodeling and thus presen...

After 30 years of seizures, George Zapien underwent epilepsy surgery at Barrow Neurological Institute and is nearing one year seizure-free.

When Attachment Advice Starts Sounding Like Neuroscience

Glioma-derived guanidinoacetate depolarizes neighboring neurons through γ-aminobutyric acid (GABA) A receptors, and depleting this metabolite reduces both neuronal activity and glioma growth.

For centuries, scientists have thought of the brain as a single, unified organ. But new research led by Stanford Medicine reveals that what we call the brain is two distinct organs that evolved indepe...

Healthy participants performed EEG-based neurofeedback (ENF) to modulate sensorimotor beta activity. Most successfully decreased beta, few increased it and learning varied by strategy, engagement and...

dopamine as an explanation for everything

A large analysis found that voice disorders are linked to a risk of cognitive decline — and they’re more common than you might assume.

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Brain imaging across more than 1,200 people identifies two reproducible reward profiles, one tuned to cues and one to outcomes. The two profiles respond in opposite ways to dopamine-blocking drugs, an...

Chen et al. show that reduced brain glucose metabolism and pathological Tau cooperate to induce neuronal death through necroptosis. By identifying a p-Tau-RIPK1 signaling hub and its regulation by A20...

Objectives To determine the range of possible prevalences of chronic traumatic encephalopathy (CTE) at death among National Football League (NFL) players and examine the association between CTE severi...

How complex mental maps and spatial reasoning protect your brain.

The man who developed a surgery to treat Alzheimer’s disease has been detained by Chinese authorities for a year and we don’t know why. According to reporting done by Elie Dolgin for Nature, there are...

Each month, The Transmitter explores different approaches neuroscientists are taking to solve various challenges. In this installment, learn how neuroscience educators are adapting their pedagogy to r...

There's something about drawing stick figures with weapons and monsters in the margins of your homework that stands the test of time.

Nature - Somatic mutations reveal the ontogeny of microglia in human aging