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Marianna Karageorgi

@mkarag.bsky.social
202 followers 164 following 36 posts

Evolutionary geneticist Adaptation to toxins across environments and timescales K99 Fellow| Marie Curie Fellow

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Reposted by Marianna Karageorgi
Pleuni Pennings @pleunipennings.bsky.social · 29/09/2026
I am hiring a postdoc! Are you interested to work on population genetics/ drug resistance/ data? Want to work in Montpellier, France? Fastq files don't scare you? PhD required, start date hopefully Nov 1! (end date Sep 30 2028) Please share! abetterscientist.wordpress.com/2026/09/29/p...
abetterscientist.wordpress.com
Postdoc position on drug resistance evolution in Montpellier, France
I have some exciting news (again!). I got money from the region (Occitanie) to hire a postdoc (and later an engineer / technician) to work on drug resistance evolution in malaria (P. faciparum) and…
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Reposted by Marianna Karageorgi
Max Telford @maxjtelford.bsky.social · 02/09/2026
Important paper by @kaplipa.bsky.social and colleagues. Advocating for the importance of Natural History museum collections in genomics. www.nature.com/articles/s41...
nature.com
Species-dense genomics through natural history collections - Nature Reviews Genetics
Large-scale genome initiatives are transforming biodiversity genomics, but genomes remain taxonomically sparse and difficult to compare across species. Kapli and colleagues argue that natural history ...
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Marianna Karageorgi @mkarag.bsky.social · 06/08/2026
Antimalaria pesticide may have backfired, helping mosquitoes find love | Science | AAAS
science.org
Antimalaria pesticide may have backfired, helping mosquitoes find love
Poison appears to have caused mutation that helps insects home in on mates in noisy cities
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Reposted by Marianna Karageorgi
womensartbluesky.bsky.social @womensartbluesky.bsky.social · 05/08/2026
'Scarlet poppies' by contemporary Impressionist style US contemporary painter Erin Hanson #WomensArt
Painting featuring a close up of red poppies growing in a field
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tomtom-auer.bsky.social @tomtom-auer.bsky.social · 18/06/2026
How do duplicated receptor genes "find a home" in olfactory circuits? Great study by the Arguello lab shows the re-coding of olfactory channels across species. Neat combination of phylogenetic reconstruction, sc-transcriptomics and more. Check out the pre-print: www.biorxiv.org/content/10.6...
biorxiv.org
Evolutionary Recoding of Olfactory Sensory Neurons
Odorant receptors ( Or s) are the interface between an animal’s nervous system and its olfactory environment. In insect genomes, the Or s are often the largest gene family, and their rapid duplication...
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Reposted by Marianna Karageorgi
Peter Andolfatto @pandolfatto.bsky.social · 16/06/2026
1/n Check out our new paper, spearheaded by @fborne.bsky.social, just out in PLoS Genetics doi.org/10.1371/jour....
doi.org
Epistasis among clustered lineage-specific amino acid substitutions in the Drosophila Trio protein
Author summary Proteins fold into three-dimensional structures that are essential for their function. Because these structures depend on interactions among amino acids, the fitness effect of a mutatio...
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Reposted by Marianna Karageorgi
Science Magazine @science.org · 07/06/2026
When caterpillars attack, the common bean plant relies on a receptor in its leaves to sound a chemical rallying cry that recruits predatory wasps, a new #ScienceAdvances study finds. scim.ag/434rXN5
scim.ag
A plant immune receptor mediates tritrophic interactions by linking caterpillar detection to predator recruitment
A plant receptor detects caterpillar attack and triggers emission of chemical cues to attract predatory wasps.
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Reposted by Marianna Karageorgi
William DeWitt @wsdewitt.github.io · 31/05/2026
Marc Feldman and Jessica Riskin with another withering critique of a "sociogenomics" popularization: "...you can’t add or subtract factors that interact, such as genetic and environmental influences. How much of a rainbow’s formation is due to moisture in the air and how much to sunlight?"
nybooks.com
Not in Your Genome | M.W. Feldman, Jessica Riskin
Generations of “sociobiologists” have tried and failed to argue that genetic analysis offers the key to understanding social inequality. A new book fares no better.
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Charikleia Karageorgiou (Clio) @evobioclio.bsky.social · 26/05/2026
Our paper on recurrent independent duplications in the primate amylase locus is now out in Cell Reports! Huge thanks to @petarpajic, @spit-lab.bsky.social and @gokcumenlab.bsky.social for their support. More about the work in the thread below from when we first shared the preprint last August.
cell.com
Convergent evolution through independent rearrangements in the primate amylase locus
Structurally complex loci can repeatedly generate similar traits; Karageorgiou et al. established primate amylase locus as a structural variation hotspot, potentially seeded by transposable elements. ...
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womensartbluesky.bsky.social @womensartbluesky.bsky.social · 06/05/2026
"Murmuration over Lanhydrock Park", 2020 by Annie Ovenden, English painter #WomensArt
Print of birds flying together in a mass, over bare trees in an evening sky
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Reposted by Marianna Karageorgi
PLOS Biology @plosbiology.org · 12/03/2026
Closely related species often exhibit distinct morphologies. Kenta Tomihara @pinharanda.bsky.social Takashi Kiuchi @pandolfatto.bsky.social &co uncover the #genetic basis of caudal horn size differences between the #SilkMoth and its wild relative @plosbiology.org 🧪 #evolution plos.io/4b3kwdR
Evolutionary diversification of Lepidopteran larval appendages. Left: Representative morphological diversity among Lepidopteran caterpillars. Phylogenetic relationships are indicated by the cladogram and family names for each representative species are indicated. Bombyx belongs to the Bombicidae (highlighted in red). Right: Representative caudal horn diversity among species in the Bombycinae sub-family. Shown are the posterior larval segments for each species; the cladogram depicts their phylogenetic relationships.
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Marcus Stensmyr @marcusstensmyr.bsky.social · 24/03/2026
Genome of the Abominable Snowfly uncovers the mysteries of cold tolerance in a winter active insect! New cool (literally) paper in @currentbiology.bsky.social from Marco Gallio, @matthewcapek.bsky.social, @tuthill.bsky.social, myself, and fine colleagues! ⛄ 🦟 authors.elsevier.com/sd/article/S...
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Jess Smiley-Rhodes @j-smiley-rhodes.bsky.social · 18/11/2025
Thrilled to finally share the magnum opus of my PhD that focuses on the genetic basis of evolutionary change! Specifically, we know we can map the genetic basis of a trait, but can we tell which genes will underlie the trait shift when it evolves? doi.org/10.1101/2025...
doi.org
High-resolution mapping of a rapidly evolving complex trait reveals genotype-phenotype stability and an unpredictable genetic architecture of adaptation
The extent to which adaptation can be predicted, particularly for traits with complex genetic bases, is unknown. Here, we leveraged a model complex trait, model species, and high-powered longitudinal ...
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Shen Tian 田申 @tianshenbio.bsky.social · 24/10/2025
My main PhD work @monteirolab.bsky.social is now in @natecoevo.nature.com! We found a Hox gene promoter that helps butterflies🦋adjust their wing eyespots in response to seasonal temperatures🍃🍂, shedding light on the evolutionary origin of phenotypic plasticity. 1/9 www.nature.com/articles/s41...
Cr. to Shen Tian
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Nastia Lyulina @alyulina.github.io · 06/11/2025
How is functional variation at large-effect loci maintained in natural populations, even as environments change? In a paper led by @mkarag.bsky.social, we tracked known pesticide resistant alleles in outdoor 𝘋. 𝘮𝘦𝘭𝘢𝘯𝘰𝘨𝘢𝘴𝘵𝘦𝘳 cages & inferred selection and dominance from temporal sequencing data.
Glass beads of all sorts balancing on wavy threads.
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Marianna Karageorgi @mkarag.bsky.social · 23/10/2025
"The most transformative technologies, ..., emerged not from goal-directed efforts but from foundational inquiries with no predetermined outcomes." #curiosity-driven_science
embopress.org
For the love of frontier research, or why Elon’s rockets keep blowing up | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
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Reposted by Marianna Karageorgi
Jeremy Yoder says no war @jbyoder.org · 30/09/2025
So this came online over the weekend: My dive into the "definition" of coevolution is online ahead of publication in @journal-evo.bsky.social! Don’t ask "when is it coevolution?" — ask "how?" doi.org/10.1093/evol...
doi.org
Don’t ask “when is it coevolution?” — ask “how?”
Abstract. Coevolution has come to be widely understood as specific, simultaneous, reciprocal adaptation by pairs of interacting species. This strict-sense
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Marianna Karageorgi @mkarag.bsky.social · 24/09/2025
Preschool teachers provide fewer participation opportunities to working-class students than those from more privileged backgrounds | PNAS www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Reposted by Marianna Karageorgi
Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 03/09/2025
Save the date! #PEQG26 June 9-12 2026 in Asilomar, CA. Happens only every 2yrs, but is my favorite conference. Full website coming soon, and registration and abstract submission opens November 14, but I'm allowed to tease that keynotes will be @jnovembre.bsky.social @jennytung.bsky.social and me!
genetics-gsa.org
Homepage - Population, Evolutionary, and Quantitative Genetics Conference
Visit our website to learn more.
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Reposted by Marianna Karageorgi
Dmitri Petrov @petrovadmitri.bsky.social · 15/09/2025
Very excited to see this work in press! I think there is a reason to believe that this is a common means of stabilizing large-effect polymorphisms in general and might be an important reason for why diploidy is so common. news.stanford.edu/stories/2025...
news.stanford.edu
Classic recessive-or-dominant gene dynamics may not be so simple
New fruit fly research provides the first direct evidence of “dominance reversal,” revealing why pesticide resistance is so hard to eliminate in changing environments.
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Marianna Karageorgi @mkarag.bsky.social · 15/09/2025
How do populations maintain an evolutionary memory? I am happy to share that our work with Dmitri Petrov @petrovadmitri.bsky.social, Paul Schmidt, and colleagues on dominance reversal and stabilization of insecticide resistance in changing environments over time is now published at Nature EE.
nature.com
Beneficial reversal of dominance maintains a large-effect resistance polymorphism under fluctuating insecticide selection - Nature Ecology & Evolution
Measuring selection and dominance in fitness of the insecticide-resistant Ace alleles in Drosophila melanogaster, the authors show evidence for beneficial reversal of dominance, a mechanism that can s...
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Reposted by Marianna Karageorgi
sharon greenblum @greensi.bsky.social · 20/08/2025
August’s Nature Plants cover story shows how we integrated large-scale multiDAP and snRNA data to reveal drivers of cell type identity and evolution in flowering plants. www.nature.com/nplants/volu... We packed a lot into this paper! Here’s a single-cell spin on what we found:
nature.com
Nature Plants - Cistromes uncovered
Transcription factors (TFs) have specific patterns of binding to gene promoter regions, which have similarities and differences within TF families and...
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Marianna Karageorgi @mkarag.bsky.social · 10/08/2025
Earlier in summer, there was a gigantic 4-year longitudinal study in France showing that the school environment triggers a gender gap in mathematics. www.nature.com/articles/s41...
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Marianna Karageorgi @mkarag.bsky.social · 01/08/2025
I was down at Pacific Grove last weekend and a volunteer shared the monarch population is declining.. #pesticides #land_use_change
theguardian.com
Monarch butterflies’ mass die-off in 2024 caused by pesticide exposure – study
New peer-reviewed research found an average of seven pesticides in each of 10 butterflies tested
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Reposted by Marianna Karageorgi
Zach B. Hancock @hancockzb.bsky.social · 12/06/2025
check out my new article published in @nautil.us on Sewall Wright's famous shifting-balance theory of evolution, told through the lens of his work with guinea pigs! nautil.us/evolution-an...
nautil.us
Evolution and Guinea Pig Toes
How one animal's oddity inspired Sewall Wright to take on one of Darwin's big ideas
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Reposted by Marianna Karageorgi
AmandaJealous @amandajealous.bsky.social · 24/04/2025
#Invertefest?! Okay! This one is a personal favorite out of all my bug art.
Milkweed Munchers. A comic strip that uses 5 tall panels. Each panel depicts a different invertebrate that relies on milkweed as a host plant. First Monarch caterpillars, one of them exclaims “Delicious!” Next, Swamp Milkweed Leaf Beetles, one beetle shouts “Exquisite!” The third panel shows a cluster of Oleander Aphids on the stem of the milkweed, several small speech bubbles that say “Yum.” are coming from the group of aphids. Then we have Large Milkweed Bugs. The adult bug says “Delectable!”. There’s a group of nymph bugs in the background. Lastly, the final featured invertebrate is the Small Milkweed Bug. The cute orange and black bug has words of praise “Tremendous Chef.” It says. Below the panels are the name of each invertebrate. Above is the title that is adorned with milkweed to the left and right. On the left the milkweeds is young and blooming and on the right the plant is older, has grown seed pods and the leaves have been consumed.
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martinswarren.bsky.social @martinswarren.bsky.social · 03/05/2025
Just noticed this in last Sunday’s Observer, a week in the life of an Orange-tip as told to Simon Barnes. Brilliant.
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Marianna Karageorgi @mkarag.bsky.social · 26/04/2025
nature.com
Answers to a 160-year-old riddle about the genetics of Mendel’s pea traits
The genetic architecture underlying differences in pod colour, pod shape and flower position in peas has finally been resolved.
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NPR @npr.org · 17/04/2025
Scientists have recently mapped the painted lady butterfly's annual flight from equatorial Africa to northern Europe and back, the world's longest butterfly migration. In Constant Bloom, photographer Lucas Foglia documents the journey.
npr.org
Photos: Scientists trace a butterfly migration route that is millions of years old
Scientists have recently mapped the painted lady butterfly's annual flight from equatorial Africa to northern Europe and back, the world's longest butterfly migration. In Constant Bloom, photographer ...
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Marianna Karageorgi @mkarag.bsky.social · 18/04/2025
Inferring Balancing Selection From Genome-Scale Data
academic.oup.com
Inferring Balancing Selection From Genome-Scale Data
Abstract. The identification of genomic regions and genes that have evolved under natural selection is a fundamental objective in the field of evolutionary
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Marianna Karageorgi @mkarag.bsky.social · 24/03/2025
nature.com
Long-term studies provide unique insights into evolution - Nature
Long-term studies provide insights into the complex interplay between evolutionary process and pattern across multiple systems and timescales.
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Reposted by Marianna Karageorgi
DrDinD.bsky.social @drdind.bsky.social · 10/03/2025
For Women's History Month, may we all remember and summon the courage of Rachel Carson, who wrote Silent Spring to inform the world what DDT was doing to the songbirds, raptors,and by extension, us. While battling cancer, she stood her ground against savage attacks by the chemical industry...
Rachel Carson
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PopGen Vienna @popgenviennaphd.bsky.social · 13/02/2025
The PopGen Vienna Seminar series schedule is ready for the next term (Mar-Jun). It's jam-packed with fantastic speakers in #evolution, #genetics, #genomics, #popgen, and more! Details and streaming link signup can be found on our website www.popgen-vienna.at/news/seminars/
PopGen Seminar Series
Summer Term 2025

04.03.25 – Lutz Becks (Univ. of Konstanz, DE)
The evolutionary dynamics of novel endosymbiosis.
11.03.25 – Ilkka Kronholm (Univ. of Jyväskylä, FI)
How chromatin structure influences genetic and epigenetic variation.
18.03.25 – Katja Hoedjes (Vrije Univ. Amsterdam, NL)
Understanding functional impact of genetic variation on complex traits at a single nucleotide resolution.
25.03.25 – Sophie Armitage (Freie Univ. of Berlin, DE)
Evolutionary ecology of host-pathogen interactions.
01.04.25 – Matthew Rockman (New York Univ., US)
Developmental evolution is a population-genetics problem.
08.04.25 – Wen-Juan Ma (Vrije Univ. Brussels, BE)
The evolution of sex chromosomes and sex determination in frogs.
15.04.25 – Almorò Scarpa (Vetmeduni, AT)
Two centuries of transposable element invasions in Drosophila melanogaster
22.04.25 – Julia Kreiner (Univ. of Chicago, US)
The mode and tempo of genomic adaptation to contemporary agriculture.
29.04.25 – Martin Kaltenpoth (Max Planck Inst. for Chemical Ecology, DE)
Microbial symbionts as sources of evolutionary innovations in beetles.
06.05.25 – Luisa Pallares (Friedrich Miescher Laboratory, DE)
Phenotypic robustness across the genotype-phenotype map, from genes to environment and back.
13.05.25 – Diana Rennison (Univ. of Calif., San Diego, US)
Understanding the predictability of evolutionary trajectories using threespine stickleback.

20.05.25 – Filipa Sousa (Univ. of Vienna, AT)
Bioenergetics Evolution: The link between Earth’s and Life’s history.
27.05.25 – Yun Song (Univ. of California, Berkeley, US)
Learning and applying complex probability distributions over biological sequences.
03.06.25 – April Wei (Cornell Univ., US)
Enabling efficient analysis of biobank-scale data with genotype representation graphs.

ALT TEXT OUT OF SPACE, GO TO https://www.popgen-vienna.at/news/seminars/
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Marianna Karageorgi @mkarag.bsky.social · 17/02/2025
A century of theories of balancing selection www.biorxiv.org/content/10.1...
biorxiv.org
A century of theories of balancing selection
Traits that affect organismal fitness are often very genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature (...
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Marianna Karageorgi @mkarag.bsky.social · 22/01/2025
How is functional variation at large-effect loci maintained in natural populations? Thrilled to share our work showing how beneficial dominance reversal helps fruit flies maintain a resistance polymorphism as selection varies in their environment! A thread 🧵 1/n www.biorxiv.org/content/10.1...
biorxiv.org
Dominance reversal maintains large-effect resistance polymorphism in temporally varying environments
A central challenge in evolutionary biology is to uncover mechanisms maintaining functional genetic variation1. Theory suggests that dominance reversal, whereby alleles subject to fluctuating selectio...
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