iiinova — where your digital self keeps evolving

Reposted by Nastia Lyulina

Bernard Kim @bernardkim.bsky.social · 15/09/2026

Princeton EEB is running a very broad faculty search at the Assistant Professor level. Please consider applying to join us! This is a wonderful, collaborative, cohesive department with diverse interests and amazing colleagues. apply.interfolio.com/193474

apply.interfolio.com

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

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Reposted by Nastia Lyulina

Dmitri Petrov @petrovadmitri.bsky.social · 17/09/2026

We are searching for an Assistant Professor in Evolutionary Biology! Looking for colleagues asking fundamental questions relating to evolutionary processes and drivers of evolutionary patterns. If you think it is you, please do apply! And please repost. facultypositions.stanford.edu/jobs/assista...

facultypositions.stanford.edu

Assistant Professor in Evolutionary Biology - Stanford University, California, United States

The Department of Biology at Stanford University seeks applicants for a tenure-track Assistant Professor in Evolutionary Biology. A successful candidate will conduct research that asks fundamental que...

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Reposted by Nastia Lyulina

Edoardo Gianni @edogia.bsky.social · 13/02/2026

How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller? Excited to share our latest work in @science.org on a new small polymerase. 1/n

science.org

A small polymerase ribozyme that can synthesize itself and its complementary strand

The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

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Reposted by Nastia Lyulina

bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 30/01/2026

Introgression under linear selection on continuous genomes www.biorxiv.org/content/10.64898/20…

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Reposted by Nastia Lyulina

Gabriel Birzu @gbirzu.bsky.social · 31/12/2025

New preprint to close out the year! Led by Alana Papula and together with Daniel Fisher, we used single-cell genomes to infer the evolution of Prochlorococcus—one of the most abundant and genetically diverse bacteria on Earth. Check it out here: doi.org/10.64898/202...

doi.org

Extensive recombination, selection, and asexual blooms shape the diversity of the dominant clade of Prochlorococcus

The tiny and enormously abundant marine cyanobacterium Prochlorococcus marinus contains many levels of population structure, with sequenced isolates spanning four orders of magnitude of diversity. It ...

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Reposted by Nastia Lyulina

G Brueckmann @brueckmann.bsky.social · 15/12/2025

Have you seen that the state of Baden-Würtenberg is funding 14 Postdoctoral Fellowships (for 2 years) for those who can't do their research in the US anymore as academic freedom is under threat? uni-freiburg.de/frias/call-f...

uni-freiburg.de

Call for Applications: Early Career Rescue Fellowship – Freiburg Institute for Advanced Studies

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Reposted by Nastia Lyulina

Grant Rotskoff @grant.rotskoff.cc · 17/12/2025

I'm hiring a postdoc with a flexible start date (any time in 2026). Come work with us on topics at the interface of machine learning, biophysics, a nonequilibrium statistical mechanics. If interested, send me a CV and a short summary of why you think you'd be a good fit. statmech.stanford.edu

statmech.stanford.edu

Rotskoff Group @ Stanford

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Nastia Lyulina @alyulina.github.io · 16/12/2025

I was supposed to attend before starting grad school, but the pandemic got in the way – if you can go, this would be a great way to explore questions in evolution!

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Reposted by Nastia Lyulina

bioRxiv Genetics @biorxiv-genetic.bsky.social · 09/12/2025

Allele Frequencies at Recessive Disease Genes are Mainly Determined by Pleiotropic Effects in Heterozygotes www.biorxiv.org/content/10.64898/20…

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Ben Good @benjaminhgood.bsky.social · 17/11/2025

We show that despite this large mutational influx, rapidly evolving pop'ns naturally cluster into a smaller # of distinct “ecotypes”, even when their genetic diversity is much larger. This non-eq analogue of competitive exclusion is driven by a dynamical priority effect that favors resident strains.

Schematic showing how a rapidly evolving population clusters into a smaller number of distinct ecotypes, comprising individuals with similar resource uptake strategies but different genotypes & overall fitness.

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Reposted by Nastia Lyulina

Ben Good @benjaminhgood.bsky.social · 16/11/2025

Many studies have found that w/in-species dN/dS decays w/ the genetic distance between strains, which is often attributed to natural selection. Here Zhiru shows that a large portion of this trend can be quantitatively explained by the accumulation of horizontally transferred DNA segments over time.

Schematic showing how homologous recombination can influence dN/dS between conspecific strains of bacteria.

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Reposted by Nastia Lyulina

Aylwyn Scally @aylwyn-scally.bsky.social · 11/11/2025

Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here. www.cam.ac.uk/jobs/faculty...

cam.ac.uk

Faculty Position in Computational Biology

Applications are invited for an Assistant/ Associate Professorship in Computational Biology to commence on 1 April 2026 or shortly thereafter. This is a joint post between the Department of Applied

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Nastia Lyulina @alyulina.github.io · 06/11/2025

How is functional variation at large-effect loci maintained in natural populations, even as environments change? In a paper led by @mkarag.bsky.social, we tracked known pesticide resistant alleles in outdoor 𝘋. 𝘮𝘦𝘭𝘢𝘯𝘰𝘨𝘢𝘴𝘵𝘦𝘳 cages & inferred selection and dominance from temporal sequencing data.

Glass beads of all sorts balancing on wavy threads.

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Reposted by Nastia Lyulina

Georgii "Yegor" Bazykin @gbazykin.bsky.social · 18/09/2025

Now hiring a computational postdoc (evolutionary genomics, molecular evolution) in my lab at Emory University. If you’re interested in population genetics, fitness landscapes, and viral evolution — get in touch. faculty-emory.icims.com/jobs/151181/...

faculty-emory.icims.com

Careers | Emory University | Atlanta GA

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Jonathan Pritchard @jkpritch.bsky.social · 07/07/2025

Staff scientist position (computational): I am looking for a computational scientist to join my genomics lab at Stanford. They should have an outstanding skillset in ML/statistical methods for genomic applications, postdoc experience and a strong publication record. #sciencejobs

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Nastia Lyulina @alyulina.github.io · 20/06/2025

Looking forward to #evolution2025! I will be talking about how time-varying demography and selection shape the site frequency spectrum — Saturday at 4:15 pm, Population Genetics Theory IV. Come say hi if you are around!

A schematic illustrating the allele frequency trajectories that contribute to a slice of the site frequency spectrum.

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Reposted by Nastia Lyulina

Jeff Spence @jeffspence.github.io · 02/06/2025

I'm excited to announce that I'll be starting a lab at UCSF in the @ihgatucsf.bsky.social and @ucsf-epibiostat.bsky.social in July. We'll work at the intersection of statistical genetics, population genetics, and machine learning.

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Karl Jacoby @karl-jacoby.bsky.social · 20/03/2025

Letter signed by members of the Columbia History Department urging resistance to the Trump Administration's efforts to dictate university policy. "Should this control be realized, here or elsewhere, it would make any real historical scholarship, teaching, and intellectual community impossible."

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Reposted by Nastia Lyulina

Fernando Rossine @fernpizza.bsky.social · 21/02/2025

Here we show that within-cell competition is key to plasmid evolution. Look at this photo of plasmids competing inside cells in a colony!!!

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Aylwyn Scally @aylwyn-scally.bsky.social · 21/02/2025

We are excited to announce a new faculty position here in Cambridge, for researchers in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Come and join us! Happy to answer questions about research, teaching and working here. www.jobs.cam.ac.uk/job/50414/

jobs.cam.ac.uk

Assistant/Associate Professor in Computational Biology - Job Opportunities - University of Cambridge

Assistant/Associate Professor in Computational Biology in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge.

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Grant Kinsler @grantkinsler.bsky.social · 17/02/2025

This allowed us to visualize the pattern of clones in the tumor! 10/16

A section of a tumor where each region of the tumor is colored by a distinct color which represents clonal growth in the tumor.

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Reposted by Nastia Lyulina

Amy Goldberg @amygoldberg.bsky.social · 16/02/2025

Project scientist in computational population genetics (post PhD/postdoc experience usually expected). recruit.apo.ucla.edu/JPF10171

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Nastia Lyulina @alyulina.github.io · 22/01/2025

Happy to have been part of this story!

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Reposted by Nastia Lyulina

Michael Baym @baym.lol · 17/01/2025

This paper has been a long time coming: We looked at the genomes of historical bacterial samples over a century to look for trends of antibiotic resistance genes, finding multiple instances of them in infections before the age of antibiotics, but an increase in both frequency and mobility after

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Reposted by Nastia Lyulina

Nikhil Milind @nikhilmilind.dev · 12/11/2024

For many traits there is a correlation between the number of duplications or loss-of-function (LoF) mutations someone carries, and their phenotype. Curiously, for most traits, these effects are aligned in the SAME direction. Why?

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Nastia Lyulina @alyulina.github.io · 19/04/2024

How do we predict the statistical associations between mutations that spontaneously emerge in an evolving population? Excited to share some new work w/ @zzzhiru.bsky.social and @benjaminhgood.bsky.social that approaches this question!

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John McEnany @johndmcenany.bsky.social · 18/12/2023

I’m excited for my first preprint in the Good lab, a theory project predicting the first steps of evolution in microbial communities with resource competition. If you’re interested in how community context shapes the availability and impact of mutations, read on! doi.org/10.1101/2023.12.15.571925

biorxiv.org

Predicting the First Steps of Evolution in Randomly Assembled Communities

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

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