Sign in

Shen Tian 田申

@tianshenbio.bsky.social
378 followers 652 following 65 posts

evolutionary innovations | noncoding RNA

PostsRepliesMedia
Reposted by Shen Tian 田申
monteirolab.bsky.social @monteirolab.bsky.social · 04/10/2026
Looking for a PhD student to help uncover whether our arms and legs, and those of insects, share the same core gene-regulatory network. If interested, please contact antonia.monteiro@nus.edu.sg. Graduate Program application deadline is 15 Nov 2026 (www.dbs.nus.edu.sg/education/gr...)
11511
Reposted by Shen Tian 田申
Jeff Groh @jeffgroh.bsky.social · 28/07/2026
Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...
pnas.org
Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNAS
In avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm of floral sex timing promotes cross-pollination between two ...
22721274
Reposted by Shen Tian 田申
Chema Martin @chemamd.bsky.social · 19/05/2026
🚨 We discovered a new mode of Hox gene regulation in annelids! 🪱 A distal enhancer acts as a "global control region", lifting Hox genes from Polycomb repression. This is reminiscent of Hox gene control in vertebrates, but the two modes likely evolved convergently. www.biorxiv.org/content/10.6...
313655
Reposted by Shen Tian 田申
Stephen Montgomery @ebablab.bsky.social · 11/05/2026
🚨Job claxon🚨 4-year #Postdoc available in our lab in @camzoology.bsky.social developing molecular and anatomical approaches to mapping evolutionary changes in the brain, using #Heliconiini butterflies. Come join us, we are nice. 🧪 www.cam.ac.uk/jobs/researc...
An immunostaining section through a Heliconius brain. Staining and imaging by Dr Max Farnworth.
26666
Reposted by Shen Tian 田申
Chris Jiggins @chrisjiggins.bsky.social · 30/04/2026
No surprise - its Optix and Ivory again - amazing predictability of gene re-use in convergent mimicry phenotypes across amazonian mimicry rings @joanameier.bsky.social @wtf-r-species.bsky.social journals.plos.org/plosbiology/...
journals.plos.org
Genetic parallelism underpins convergent mimicry coloration in Lepidoptera across 120 million years of evolution
The repeated evolution of similar phenotypes, or convergent evolution, is widespread in nature, but there are few studies investigating the genetic mechanisms across wide evolutionary timescales. This...
15920
Reposted by Shen Tian 田申
Parichy Lab | Dave Parichy @dparichy.bsky.social · 03/04/2026
Zebrafish finds Nemo. New paper with our great collaborators on gap junctional communication in widely divergent species. www.nature.com/articles/s41...
23915
Shen Tian 田申 @tianshenbio.bsky.social · 27/02/2026
Amazing peppered moth story from Saccheri lab - same locus, but different structural variants, underly parallel evolution of industrial melanism in the UK and across continental Europe.
13618
Shen Tian 田申 @tianshenbio.bsky.social · 13/02/2026
A mini review on the seasonal plasticity of butterfly eyespots. www.sciencedirect.com/science/arti...
061
Reposted by Shen Tian 田申
Marcus Hicks @marcushicks.bsky.social · 23/01/2026
Very excited to share that my first first-author pre-print is out today! Many thanks go out to all of our collaborators, especially those who helped with the fieldwork in Peru - it really wouldn't have been possible without you! 🦋
12110
Reposted by Shen Tian 田申
tirthabanerjee.bsky.social @tirthabanerjee.bsky.social · 23/01/2026
Evolution rarely invents from scratch. Our recent study reveals that butterfly eyespots evolved by co-opting an ancient wing vein gene network. New trait, old genes. The study is now published in Communications Biology (featured: Jan26) www.nature.com/articles/s42...
041
Reposted by Shen Tian 田申
Casey Dunn @caseywdunn.bsky.social · 09/01/2026
Our eLetter github.com/caseywdunn/s... responding to a recent Science paper was just posted. The paper found more genes with consistent support for sponge-sister than ctenophore-sister. We found several technical issues that, when corrected, reverse the conclusions and recover ctenophore-sister.
513257
Reposted by Shen Tian 田申
Graham Coop @gcbias.bsky.social · 25/12/2025
Congrats @jeffgroh.bsky.social et al. Some avocado trees open female-phase flowers in the morning & then male in afternoon. Others show complementary pattern (m->f), to synchronize pollination of two types. Jeff show this to be a >45Mya polymorphism at a transcription factor across 100s of species.
114261
Reposted by Shen Tian 田申
Jonathan Pritchard @jkpritch.bsky.social · 11/12/2025
GWAS has been an incredible discovery tool for human genetics: it regularly identifies *causal* links from 1000s of SNPs to any given trait. But mechanistic interpretation is usually difficult. Our latest work on causal models for this is out yesterday: www.nature.com/articles/s41... A short🧵:
nature.com
Causal modelling of gene effects from regulators to programs to traits - Nature
Approaches combining genetic association and Perturb-seq data that link genetic variants to functional programs to traits are described.
318682
Reposted by Shen Tian 田申
Emilio Mármol Sánchez @marmole6.bsky.social · 14/11/2025
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social www.cell.com/cell/fulltex... If you want to know more, read the 🧵 below:
111142
Reposted by Shen Tian 田申
🧬Jacob L Steenwyk @jlsteenwyk.bsky.social · 13/11/2025
NEW pub in @science.org 🥳 Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life? For over 15 years, #phylogenomic studies have been divided. We provide new evidence suggesting that... 🔗: www.science.org/doi/10.1126/...
14283130
Reposted by Shen Tian 田申
Judy Li (李静迪) @jingdi.bsky.social · 09/11/2025
Hi, I'm setting up a peer support platform for ECRs in ecology & evolution in China, aiming to address a huge problem --- academic burnout driven by hyper-competition and a system that often prioritizes elite background/title over actual research. #ECR #AcademicSupport #科研互助 #ecology #evolution
187
Reposted by Shen Tian 田申
The Fromm Lab @frommlab.bsky.social · 21/10/2025
🔥🔥🔥🔥New paper out; a opinion piece in @narjournal.bsky.social with Michael Hackenberg, @panosbino.bsky.social, Kevin K Peterson and @marcfriedlander.bsky.social 🔥🔥🔥🔥 „Knowing is not enough, we must apply“ academic.oup.com/nar/article/...
media.tenor.com
a statue of a man 's head with a bunch of paper coming out of it
ALT: a statue of a man 's head with a bunch of paper coming out of it
0105
Reposted by Shen Tian 田申
Vicencio Oostra @climate-adaptation.bsky.social · 03/11/2025
PhD position for Chinese nationals! London-based, funded by China Scholarship Council & @qmul.bsky.social "Ecology & genomics of climate adaptation: mapping functional genetic variation in wild insect populations" shorturl.at/Vfi8W DM for more info! #conservation #genomics #ecology #biodiversity
Project overviewAbout the labEntry requirements Funding & eligibility
145
Reposted by Shen Tian 田申
Dr Mark E Hauber @thecowbirdlab.bsky.social · 30/10/2025
www.science.org/doi/10.1126/...
science.org
Genomic architecture of egg mimicry and its consequences for speciation in parasitic cuckoos
Host-parasite arms races facilitate rapid evolution and can fuel speciation. Cuculus cuckoos are deceptive egg mimics that exhibit a broad diversity of counterfeit egg phenotypes, representing host-ad...
02010
Reposted by Shen Tian 田申
Patrícia Beldade @pbeldade.bsky.social · 29/10/2025
A personal favorite, long time in the making. Adelina and David (@dduneau.bsky.social) were instrumental in getting this done. doi.org/10.1186/s129...
doi.org
Wound-induced eyespots on butterfly wings at the intersection of immune response and pigmentation development - BMC Biology
Background Butterfly eyespots are striking examples of evolutionary novelty arising through the repurposing of ancestral genetic pathways, including pathways involved in wound healing. Given the activ...
0149
Reposted by Shen Tian 田申
monteirolab.bsky.social @monteirolab.bsky.social · 28/10/2025
For those interested in GRN evolution, please join us!
1108
Reposted by Shen Tian 田申
monteirolab.bsky.social @monteirolab.bsky.social · 25/10/2025
news.nus.edu.sg/dna-switch-b...
news.nus.edu.sg
NUS study: A simple DNA switch helps tropical butterflies change wing patterns with the seasons
Singapore, 24 October 2025 — Scientists from the National University of Singapore (NUS) have discovered a simple DNA “switch” that helps tropical butterflies adjust the size of their wing eyespots in ...
073
Shen Tian 田申 @tianshenbio.bsky.social · 24/10/2025
A news article about the paper by Jennifer Brisson: www.nature.com/articles/s41...
nature.com
Genetics of butterfly eyespot plasticity - Nature Ecology & Evolution
Transcriptional and functional analyses reveal a taxon-specific promoter at the Antennapedia gene that is responsible for seasonal plasticity in butterfly eyespots.
031
Reposted by Shen Tian 田申
Di Jiang @dijiang319.bsky.social · 23/10/2025
This study @science.org finds what appears to be the long-lost RNA subunit of C. elegans telomerase. The TERC RNA is encoded within an intron of a germline-upregulated gene, nmy-2🪱🔬🧬Nematode telomerase RNA hitchhikes on introns of germline–up-regulated genes | Science www.science.org/doi/10.1126/...
14614
Shen Tian 田申 @tianshenbio.bsky.social · 24/10/2025
My main PhD work @monteirolab.bsky.social is now in @natecoevo.nature.com! We found a Hox gene promoter that helps butterflies🦋adjust their wing eyespots in response to seasonal temperatures🍃🍂, shedding light on the evolutionary origin of phenotypic plasticity. 1/9 www.nature.com/articles/s41...
Cr. to Shen Tian
27126
Reposted by Shen Tian 田申
Tarunkishwor Yumnam ꯇꯔꯨꯟ ꯌꯨꯝꯅꯥꯝ @tarunyumnam.bsky.social · 16/10/2025
1/3 Excited that my final PhD MS is online! Big thanks to Ullasa (PI) (vanasiri.in) & collaborators Freerk and Urszula. Turns out humidity, not just temperature, plays a major role in butterfly eyespot plasticity. doi.org/10.1101/2025...
1279
Reposted by Shen Tian 田申
eric lai @lucksmith.bsky.social · 12/09/2025
New #miRNA paper from Lai lab!! 🧬🔥 some think this field, despite recent Nobel to Ambros and Ruvkun, doesn't have much surprises left. but, do we EVEN KNOW WHAT a miRNA precursor LOOKS LIKE? we found some conserved miRNA hairpins up to 10x longer than suspected. this is mir-12, just bonkers! 1/n
12816
Reposted by Shen Tian 田申
Luisa Cochella @lcochella.bsky.social · 03/09/2025
Our work on the function of miR-51/miR-100 is out! miR-100 is widely conserved across eumetazoans but its function has been mysterious. Emilio Santillán found in worms it regulates signaling and extracellular matrix genes, some of which seem to be conserved targets! www.science.org/doi/10.1126/...
science.org
An ancient and essential miRNA family controls cellular interaction pathways in C. elegans
A microRNA that arose at the origin of eumetazoans regulates cell adhesion and signaling in C. elegans through conserved targets.
59335
Reposted by Shen Tian 田申
Timothy Fuqua @timothyfuqua.bsky.social · 28/08/2025
Excited / nervous to share the “magnum opus” of my postdoc in Andreas Wagner’s lab! "De-novo promoters emerge more readily from random DNA than from genomic DNA" This project is the accumulation of 4 years of work, and lays the foundation for my future group. In short, we… (1/4)
biorxiv.org
De-novo promoters emerge more readily from random DNA than from genomic DNA
Promoters are DNA sequences that help to initiate transcription. Point mutations can create de-novo promoters, which can consequently transcribe inactive genes or create novel transcripts. We know lit...
417159
Reposted by Shen Tian 田申
Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 15/08/2025
Music to my ears. This is brilliant. Either 90% of us can claim to be better musicians than Beethoven or… maybe just maybe polygenic scores aren’t perfect?
29435
Reposted by Shen Tian 田申
闵娅(Min Ya; Minya) PhD @minyaaa.bsky.social · 12/08/2025
My sister department EEB is hiring an animal evo-devo assistant prof! I'm the plant evo-devo person on the SC and happy to answer any questions! (spoiler alert: This is a GREAT place to be and with fantastic colleagues & support!!!!) @socdevbio.bsky.social illinois.csod.com/ux/ats/caree...
illinois.csod.com
Assistant Professor, Evolution, Ecology & Behavior
Duties & Responsibilities
24545
Reposted by Shen Tian 田申
monteirolab.bsky.social @monteirolab.bsky.social · 02/08/2025
Here is a very detailed examination on how pigmentation in the cuticle of a butterfly wing scale changes the density and refractive index of chitin and, thus, also alters structural color. rdcu.be/eyUwS
rdcu.be
Nanoscale cuticle mass density variations influenced by pigmentation in butterfly wing scales
Nature Communications - Here, the authors investigate the interaction of pigment distribution and cuticle density within butterfly wing scales. They use ptychographic X-ray computed tomography to...
092
Reposted by Shen Tian 田申
Kaessmann Lab @kaessmannlab.bsky.social · 16/07/2025
Our study on a male-essential microRNA and the evolution of other dosage compensation mechanisms in birds is now out in Nature! www.nature.com/articles/s41...
nature.com
A male-essential miRNA is key for avian sex chromosome dosage compensation - Nature
Birds have evolved a unique sex chromosome dosage compensation mechanism involving the male-biased microRNA (miR-2954), which is essential for male survival by regulating the expression of dosage-sens...
1012358
Reposted by Shen Tian 田申
Wouter van der Bijl @vdbijl.bsky.social · 01/07/2025
🚨 Super exited to see our paper on the inheritance and genetic basis of guppy color variation come out in @natecoevo.nature.com‬ rdcu.be/eugWV Guppy males have enormous variation in color patterns, with many combinations of ornamental spots and stripes. But where does all this variation come from?
Photo of guppy males from lab population, each showing a unique combination of black and orange ornaments. Photo by Wouter van der Bijl.
310741
Shen Tian 田申 @tianshenbio.bsky.social · 24/05/2025
Glad to share the final piece of my PhD thesis. We discovered a novel Hox gene promotor that might have facilitated the evolution of phenotypic plasticity across a butterfly subfamily. www.biorxiv.org/content/10.1...
biorxiv.org
A novel Hox gene promoter fuels the evolution of adaptive phenotypic plasticity
Adaptive phenotypic plasticity allows organisms to display distinct phenotypes in response to variable environments, but little is known about the genomic changes that promote the evolution of plastic...
0167
Reposted by Shen Tian 田申
PlantEvolution 🌱🌾 @plantevolution.bsky.social · 09/05/2025
It is sad that even basic research needs to be defended with utility. For me, basic research is in the same category as art: civilized societies can't do without it, because we all want to know who we are and what our place in the natural world is -- questions that only science can answer.
715961
Reposted by Shen Tian 田申
Arnaud Martin @evolvwing.bsky.social · 17/12/2024
New preprint by butterfly wizard @lucalivraghi.bsky.social www.biorxiv.org/content/10.1... We mapped optix (again?!) as the switch gene of a natural polymorphism, this time controlling silver patches of a mountain butterfly. Gorgeous RNAi validation, evidence of selective sweeps, introgression
110754
Reposted by Shen Tian 田申
tirthabanerjee.bsky.social @tirthabanerjee.bsky.social · 12/12/2024
Our new manuscript describing gene multiplexing (using RAM-FISH) is finally out... We profiled multiple known and novel mRNA candidates during different developmental stages of Bicyclus and zebrafish using the easy-to-use HCR-based protocol that most labs can adapt. www.biorxiv.org/content/10.1...
021
Reposted by Shen Tian 田申
Christie Wilcox @nerdychristie.bsky.social · 09/12/2024
Small but mighty: The differences in these two butterflies' wings are driven by a microRNA, a discovery that solves a longstanding genetic mystery. That and more of the best in @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪 🦋
Mir-193 mutant Bicyclus anynana butterfly with lighter wings and no black spots (top) and a wild-type (below). Credit: Shen Tian
28016
Shen Tian 田申 @tianshenbio.bsky.social · 06/12/2024
Here’s a video about the story, made by prof. Antonia Monteiro’s daughter Florence. youtu.be/xsjlZWldn8s?...
youtu.be
miR-193 - the story of a micro-RNA's mega impact
YouTube video by Antonia Monteiro
1145
Shen Tian 田申 @tianshenbio.bsky.social · 05/12/2024
Our miRNA story is now in @science.org ! We found a microRNA, not a protein, that finally solved a long-standing evolutionary mystery of wing coloration in butterflies and moths. (1/n) www.science.org/doi/10.1126/...
science.org
A microRNA is the effector gene of a classic evolutionary hotspot locus
In Lepidoptera (butterflies and moths), the genomic region around the gene cortex is a “hotspot” locus, repeatedly implicated in generating intraspecific melanic wing color polymorphisms across 100 mi...
12246106
Reposted by Shen Tian 田申
Anyi Mazo-Vargas @anyimv.bsky.social · 19/11/2024
🌟 Introducing the Mazo-Vargas Lab @DukeU. 🌟 🧬 We employ #genetics, #functional-genomics, and #evodevo approaches to untangle the genetic basis of morphological adaptive traits.
Five members of the Mazo-Vargas laboratory are standing at the Duke University campus, with tiered grassy steps and autumn trees, under a sky with scattered clouds.
1274