iiinova — where your digital self keeps evolving

Reposted by Mike Pazin

Jeremy Berg @jeremymberg.bsky.social · 01/10/2026

From a discussion of updating a department website...

A photo with baby Yoda and adult Yoda with the caption "Could it be time for a new photo?"

934670

Reposted by Mike Pazin

Sonya Neal @neal-lab.bsky.social · 02/09/2026

Come be my colleague!! 🎉 We’re hiring an Assistant Professor in Developmental Biology at UCSD! If you’re doing exciting work in development or regeneration, come join us!! Please spread the word and apply! apol-recruit.ucsd.edu/JPF04591

apol-recruit.ucsd.edu

Assistant Professor of Developmental Biology

University of California, San Diego is hiring. Apply now!

3150129

Reposted by Mike Pazin

Samantha Butler @samanthabutler.bsky.social · 02/09/2026

Please spread the news - the Department of Neurobiology at UCLA is hiring. This is an open rank search for all and any amazing neuroscientists! Please apply here by Nov 15th, first review end of October : recruit.apo.ucla.edu/JPF11296

recruit.apo.ucla.edu

Open-rank tenure-track faculty position

University of California, Los Angeles is hiring. Apply now!

06965

Reposted by Mike Pazin

Graham Erwin @grahamerwin.bsky.social · 18/08/2026

The Baylor College of Medicine Conference on Structural Variants and DNA Repeats is back, and this year it has a new home! Join us in person in Houston November 19th–20th. Or join online. Virtual registration is FREE! ErwinLab.org/svar-conference

168

Reposted by Mike Pazin

Shawn Burgess @burgesslab.bsky.social · 30/07/2026

Yet another #zebrafish genome update: We just updated our ZebrafishGenomics public datahub for the UCSC browser (available all the way at the bottom here: genome.ucsc.edu/cgi-bin/hgHu...). We added several useful tracks including:

genome.ucsc.edu

11410

Reposted by Mike Pazin

Nucleic Acids Research @narjournal.bsky.social · 31/07/2026

📣NAR is recruiting a new Executive Editor!📣Seeking an established researcher with expertise in RNA biology and translation mechanisms to help shape the journal's scientific direction, oversee peer review, and support its growth. Apply by 30 Sept 2026: academic.oup.com/nar/pages/ex...

01410

Reposted by Mike Pazin

Itai Yanai @itaiyanai.bsky.social · 15/07/2026

‘Inhabiting the data’ is how CalTech Professor Ellen Rothenberg describes her process for coming up with a new idea, in the very first episode of the Night Science Podcast. (@nightsciencepod.bsky.social)

2127

Reposted by Mike Pazin

Atlas of Variant Effects Alliance @varianteffect.bsky.social · 01/07/2026

Missed Abbye McEwan's excellent introduction to MAVE technology? It's now available on YouTube: www.youtube.com/watch?v=FeUp... Learn more about how to use MAVE data to inform clinical variant classification, and discover how these datasets may help resolve variants of uncertain significance.

youtube.com

VSN presents Beyond the VUS Using MAVE Data to Inform Clinical Variant Classification

YouTube video by Variant Scientists Network

032

Reposted by Mike Pazin

Randall Munroe @xkcd.com · 02/07/2026

Asteroid Threat xkcd.com/3265/

Comic. [Two images of Earth, one centered on Africa, with a dotted line behind, and the other in the foreground with a target marked in the Indian Ocean.] [caption] Dire news: An asteroid is on course to hit the Earth exactly *opposite* the Yucatán Peninsula, bringing *back* the dinosaurs.

11383661425

Reposted by Mike Pazin

Jeremy Berg @jeremymberg.bsky.social · 25/06/2026

Foundational! "The scientist doing basic research may not be at all interested in the practical applications of his work, yet the further progress of industrial development would eventually stagnate if basic scientific research were long neglected." From Science: The Endless Frontier, Bush, 1945

09235

Reposted by Mike Pazin

Oded Rechavi @odedrechavi.bsky.social · 19/06/2026

Nothing is more annoying than seeing a badge telling you there's one unread message or task in an app, then going through every corner of the app and not finding it.

2414

Reposted by Mike Pazin

Atlas of Variant Effects Alliance @varianteffect.bsky.social · 17/06/2026

Don't miss Abbye McEwen's deep dive into interpretation of variants of unknown significance (VUS) - happening today (12.00 pm ET / 9.00 am PT / 5.00 pm BST). Join here: bit.ly/3Seq0LL #DeepMutationalScanning #VariantScientistNetwork #AtlasOfVariantEffects

021

Reposted by Mike Pazin

Atlas of Variant Effects Alliance @varianteffect.bsky.social · 15/06/2026

This Wednesday, are you ready to go beyond the VUS and learn more about using multiplexed assays of variant effects (MAVEs) to inform clinical variant classification? It's free to sign up: bit.ly/3Seq0LL #DeepMutationalScanning #VariantScientistNetwork #VUS #MAVE #AtlasOfVariantEffects

023

Reposted by Mike Pazin

Michael Love @mikelove.bsky.social · 30/04/2026

Bioconductor 3.23 is released! Thanks to the core team for all the hard work that goes into a release, and to the package reviewers. The lab has a bunch of updates in here that I'll post in 🧵 over the next few days:

13715

Reposted by Mike Pazin

Itai Yanai @itaiyanai.bsky.social · 12/04/2026

There's a strange myth about science: that theory comes first, and that data cannot show anything new. But anyone who's ever done science knows the truth that there's a long conversation between data & hypotheses. Back & forth.. until the discovery. And if you think about it, it has to be this way!

54910

Reposted by Mike Pazin

National Academy of Sciences @nasonline.org · 06/04/2026

Congratulations to NAS President-Elect @neilshubin.bsky.social on winning @sse-evolution.bsky.social's Stephen Jay Gould Prize! The award honors individuals who have advanced public understanding of evolutionary science in the spirit of #NASmember Stephen Gould. evolutionsociety.org/index.php?mo...

2397

Reposted by Mike Pazin

Itai Yanai @itaiyanai.bsky.social · 03/04/2026

Professors: come get trained by us in how to teach the Night Science Workshop on the creative scientific process to your students who are thirsty for this material! Our Train-the-Trainer 1day program in NYC April 24 is in partnership with the NY Academy of Sciences! night-science.org/train-the-tr...

0154

Reposted by Mike Pazin

Job Dekker @jobdekker.bsky.social · 17/12/2025

A major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists! www.nature.com/articles/s41...

nature.com

An integrated view of the structure and function of the human 4D nucleome - Nature

The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitatin...

211055

Reposted by Mike Pazin

Neil deGrasse Tyson @neildegrassetyson.com · 17/05/2025

The 80-year recipe stoking America’s Prosperity: 1) Free-market capital investments in brilliant ideas… 2) enabled by Engineering Innovations… 3) based on Science Research in Universities… 4) funded by Grants from the US Government. It’s time more people understood this.

36089392942

Mike Pazin @mikepazin.bsky.social · 05/05/2025

I ran the Pittsburgh marathon Sunday. I was thrilled with how the race and training went. Personal record for me for marathon, and better than my target for today. Thanks to my partner Andrea and my sons and Tiny Dog for their support from training to race day (coach Jack!).

030

Mike Pazin @mikepazin.bsky.social · 29/04/2025

I ran the Nashville Rock ‘n’ Roll half marathon Saturday, benefitting cancer research at St. Jude Children’s Research Hospital. I loved running “with” my son. Personal record for me. Last tune up before next week’s marathon. I love that money is being raised to improve people’s health.

080

Reposted by Mike Pazin

Carl de Boer @carldeboer.bsky.social · 20/03/2025

Last call for a postdoc position in single cell analysis/perturb-seq with @nikashakiba.bsky.social at UBC in beautiful Vancouver Canada! ubc.wd10.myworkdayjobs.com/en-US/ubcfac...

0710

Reposted by Mike Pazin

Our World in Data @ourworldindata.org · 20/03/2025

Women live longer than men, but how much longer varies widely around the world

A world map illustrates the differences in life expectancy between females and males at birth in 2023. Areas shaded in darker purple indicate a greater male life expectancy compared to females, while lighter shades represent regions with higher female life expectancy. Notable data points include Ukraine with a difference of 13.3 years, Russia at 11.8 years, Togo at 0.4 years, and Nigeria at 0.6 years. The data source is the Human Mortality Database (2024) and UN World Population Prospects (2024). The map is attributed with a CC BY license and published by Our World in Data.

3487

Reposted by Mike Pazin

Arjun Raj @arjunraj.bsky.social · 18/03/2025

Sitting in a journal club-style class right now and after the main presenters present, there are "roles" from others in the group, like the "archeologist" who looks into the citation trail, the "private investigator" who tries to dig into the history, and the "industry practitioner", etc. Cool idea!

45613

Reposted by Mike Pazin

Benoit Bruneau @benoitbruneau.bsky.social · 17/03/2025

oh this is so good

0455

Mike Pazin @mikepazin.bsky.social · 16/03/2025

Analysis of NIH found that for every $1.00 of funded research there was $2.56 in economic activity. See the jobs created and economic activity in your state. Read recent research highlights. The “business” of the NIH is improving our health. www.unitedformedicalresearch.org/wp-content/u...

unitedformedicalresearch.org

060

Reposted by Mike Pazin

Science Friday @scifri.bsky.social · 16/03/2025

90% of people diagnosed with pancreatic cancer die from the disease. That's why the medical community is excited about the results of a small trial in which nearly half of the pancreatic cancer patients who received an mRNA vaccine for the disease remained relapse-free three years later.

sciencefriday.com

A Vaccine For Pancreatic Cancer Continues To Show Promise

In a small trial, nearly half of pancreatic cancer patients who received an mRNA vaccine for the disease had no relapse three years later.

819325147643

Mike Pazin @mikepazin.bsky.social · 15/03/2025

I ran the DC Rock ‘n’ Roll half marathon today, benefitting cancer research at St. Jude Children’s Research Hospital. I was thrilled with how the race and training went. Personal record for me, much better than my previous best half marathon, and better than my target for today.

150

Mike Pazin @mikepazin.bsky.social · 12/03/2025

Nice work assessing the effects of genetic variants in primary human T cells leading to enhanced T cell immunotherapy youtu.be/jO6ybztQnzs?...

youtu.be

"Massively scalable assessment of variant effects in primary human T cells" - Zachary Walsh

YouTube video by Variant Effects

000

Reposted by Mike Pazin

Eric Topol @erictopol.bsky.social · 10/03/2025

Who funds biomedical research? @nature.com www.nature.com/articles/d41...

16610302

Reposted by Mike Pazin

danapeer.bsky.social @danapeer.bsky.social · 11/03/2025

Congratulations to the new fellows.

033

Mike Pazin @mikepazin.bsky.social · 07/03/2025

I think this short video does a great job explaining why we should all be happy that a small portion of our tax dollars funds basic research youtu.be/GmhD-RWNL6c?...

youtu.be

*Winner* Funding Basic Science to Revolutionize Medicine, 2013 FASEB Stand Up for Science

YouTube video by Federation of American Societies for Experimental Biology

000

Mike Pazin @mikepazin.bsky.social · 05/03/2025

Exciting seminar on calibrating results from high-throughput functional genomics assays and predictive models for clinical interpretation. youtu.be/TY-C7Dz-Wi4?... @shawnfayer.bsky.social @dougfowler.bsky.social @leastarita.bsky.social #VESS

youtu.be

"Reassessing the Calibration of Variant Effect Predictors for Clinical Interpretation"

YouTube video by Variant Effects

0226

Mike Pazin @mikepazin.bsky.social · 04/03/2025

Exciting seminar on understanding receptor-ligand signaling using mutational scanning. How does a receptor decode ligands to decide whether to signal, or how strongly? youtu.be/hDlJU6HI9Os?...

youtu.be

"Mutational scanning to understand ligand efficacy and potency in GPCRs"- Matthew Howard

YouTube video by Variant Effects

031