My second paper of the year finally out!
While the Polycomb field is dominated by models based on a tight functional coupling between PRC1 and PRC2, we found compelling evolutionary support for the predominantly independent functions of PRC1 and PRC2.
www.nature.com/articles/s42...
nature.com
Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1 - Communications Bi...
A systematic characterization of the Polycomb system throughout the eukaryotic tree of life reveals that evolution of PRC1 and PRC2 has been largely uncoupled.