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Manny Ares 👀

@mannyares.bsky.social
1.6K followers 1.2K following 1.1K posts

"RNA is the love language of the genome." Science person, RNA fan, lab account over at areslab.bsky.social Interested in RNAs that must adopt two or more distinct structures to function. Also interested in mechanisms of intron gain during genome evolution.

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Dr. Sarah Parcak @indyfromspace.bsky.social · 5h
Yes I admit it. It's me. I am guilty of indoctrinating my students when I tell them "Read the syllabus" "Come to class" and "Turn in your work on time." Truly socialist stuff forcibly injected into their arms each week. You should see me talking about the final paper.
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Tressie McMillan Cottom @tressiemcphd.bsky.social · 6h
“What’s the denominator??” Me, a gazillion times a day to a gigazillion people.
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Manny Ares 👀 @mannyares.bsky.social · 5h
...going to donate to the Sun for a while.
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Manny Ares 👀 @mannyares.bsky.social · 5h
this spring would be my 50th reunion - A lot has changed since then but sadly many things that should have been addressed long ago have not. An opportunity to lead in the exorcism of those things is presenting itself - let's hope for better.
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Manny Ares 👀 @mannyares.bsky.social · 6h
oof
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Scott Bagley @bagphos.bsky.social · 16/10/2026
List of things to fix before allowing people to drive flying cars: 1: people driving regular cars 2: everything else
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Richard Sever @richardsever.bsky.social · 7h
"Because manuscripts reflected real progress towards our field’s goals, our assessment systems began relying on them as primary metrics...which is obviously flawed...Generative AI has broken this already-flawed proxy completely" journals.plos.org/plosbiology/...
journals.plos.org
What is biology research for?
In the age of generative artificial intelligence (AI), the assumption that writing a paper requires doing science no longer holds true. Before deciding how to respond to the surge of AI-generated pape...
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Karen “the good kind” @kpsinging.bsky.social · 16/10/2026
Outstanding 😁😁
Grace @gracearnprie posted

my mom used to watch jeopardy early on a different city's channel so that when she would watch it w my dad later she'd know all the answers. she's still never told him so he's been under the impression that she's a genius this whole time
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Carl T. Bergstrom @carlbergstrom.com · 16/10/2026
I'm thrilled to share my first foray into nature writing. I describe my travels through Aotearoa New Zealand to see the country's rarest birds—and use this as a vehicle to tell the stories of the islands' evolutionary history and the bold conservation efforts that saved these creatures. Gift link
bloomberg.com
The Birds I Waited 45 Years to See
An evolutionary biologist returns to New Zealand to find the rare birds he dreamed of seeing as a child making an extraordinary comeback.
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Mike @mike-umbkm.bsky.social · 16/10/2026
GOP Senate nominee Ashley Hinson, who has repeatedly voted against ending the Iran war, asks people to donate gas money for her campaign bus
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Berna Devezer @devezer.bsky.social · 23h
so ok when your work and posts are critical of a field, pushback is expected so i'm not gonna act scandalized. however, here is something that happens repeatedly in metascience: i get verbally insulted by dudes who ultimately agree with all of my arguments. and *that* is a gendered dynamic.
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Manny Ares 👀 @mannyares.bsky.social · 22h
I hear you - but I'm not confident this government will act in the public interest. Some definitions predate useful mRNA transfection experiments. Comments on this might lead to clarification, even of longstanding terminology. The FDA... welp, institutions are not what they were.
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Manny Ares 👀 @mannyares.bsky.social · 16/10/2026
Agree it is hard, and needs to satisfy experts and citizens alike. I think this definition needs improvement so that it can't be weaponized outside of its specific intended research-based application.
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Manny Ares 👀 @mannyares.bsky.social · 16/10/2026
I am worried about how these terms are evolving - most folks probably don't think of the covid mRNA vaccine as a gene therapy. I think the distinction between permanent alterations (whether germ line heritable or not) and transient, physiological alterations is worth strengthening.
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Manny Ares 👀 @mannyares.bsky.social · 16/10/2026
I guess I am worried about new nefarious interpretations. One of the vaccine misinformation stories is that it "changes your DNA." This defines recipients of a transient expression construct (eg all of us who got the covid RNA vaccine) as GMOs. Shouldn't it be more specific?
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Drug Monkey @drugmonkey.bsky.social · 16/10/2026
Imagine a future when every new NOTice from NIH draws enthusiastic cheers from the extramural research community instead of frantic calls to action.
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Jamie Cate @jhdcate.bsky.social · 16/10/2026
Comment posted!
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Manny Ares 👀 @mannyares.bsky.social · 16/10/2026
#NIH #mRNA #vaccines transient expression ≠ genetic modification
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Manny Ares 👀 @mannyares.bsky.social · 16/10/2026
⚠️ Another problematic NIH policy needs your attention ⚠️ NOT-OD-26-112: grants.nih.gov/grants/guide... Redefines transient expression as "genetic modification". If adopted, mRNA medicines could be forbidden. Comments close October 19! Please go comment on this! osp.od.nih.gov/comment-form...
Screenshot of concerning policy proposal redefining "genetic modification".
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In Preparation @inprep.bsky.social · 16/10/2026
inpreparation.substack.com
Opinion: Fuck This Fucking Projector
By Prof. Russell Huang, Associate Professor of Organic Chemistry, University of Illinois at Urbana-Champaign
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conifergirl.bsky.social @conifergirl.bsky.social · 14/10/2026
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Fossillocator @fossillocator.bsky.social · 15/10/2026
Be careful out there
Check your Halloween candy carefully. Someone tried to hide the Cretaceous-Paleogene boundary layer in mine. Snickers image with the KPg boundary
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UNLEASH @unleash-as.bsky.social · 14/10/2026
Part of the UNLEASH team from the Valcárcel lab (@crg.eu) is at @embl.org Heidelberg for the Complex Life of RNA conference #EESRNA. Today, Mónica gave a fantastic talk on the characterisation of small molecules modulating splicing!
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Jason Rasgon @vectorgen.bsky.social · 14/10/2026
This is a new one. Just resubmitted a manuscript & it got kicked back for having an "iThenticate score higher than the acceptable limit". i.e. accusing us of plagiarism. Want to know what it flagged? The fucking bioRxiv preprint. Do humans not review this bullshit before it's sent out? I hate AI
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Introvert Problems @introvertproblems.bsky.social · 14/10/2026
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aaron 👻🎃💀 @hillenjoyer.myatproto.social · 14/10/2026
the problem with recommending anything because you bought it fifteen years ago and it’s lasted is thats no guarantee that the ones they’re selling today will because tricking you into overpaying for something that resembles a product that used to be good is one of the two business models now
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Aaron and the Hoskins Lab at UW Madison @uwmadisonrna.bsky.social · 13/10/2026
I'm excited about next week's RNA Maxigroup featuring @kathyliulab.bsky.social from Penn! Thanks to @rnasociety.bsky.social @uwbiochem.bsky.social @bmolchem.bsky.social and the CMB program for funding!
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Junior RNA scientists @jrrnascientists.bsky.social · 13/10/2026
Meet our panelist Laura M. Hertz. Kindly register here: lnkd.in/gpezQN95
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Manny Ares 👀 @mannyares.bsky.social · 14/10/2026
I couldn't get that msn thing to run - is this the paper? www.pnas.org/doi/10.1073/...
pnas.org
Human lncRNA RMRP interacts with DEAD-box helicases and modulates mitochondrial function | PNAS
The human long noncoding RNA (lncRNA) RMRP, initially identified as part of the RNase MRP complex, is linked to various human diseases. However, it...
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Manny Ares 👀 @mannyares.bsky.social · 14/10/2026
It's the curse of the avant guard. Learn to chain smoke and wear a beret.
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North Carolina Conference of the AAUP @ncaaup.bsky.social · 14/10/2026
A haunted house where every room has an assistant dean for teaching excellence and vice chancellor for finance
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the abbot of unreason (an archaeologist) @merovingians.bsky.social · 14/10/2026
I don't know that it makes him presidential material but Ossoff's ability to just be honest about how much of a pile of shit these people really are should be a model to the party.
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Claire Willett @clairewillett.bsky.social · 14/10/2026
after so many years of Civility™️ and Reaching Across the Aisle™️ and Bipartisanship™️, we are so hungry for anyone to just flat-out say “are you a whole-ass criminal y/n, trick question it’s yes and we have proof” right to their faces it hits like ice-cold peppermint schnapps
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Andrea Pitzer @andreapitzer.bsky.social · 14/10/2026
Somebody is going to report Ossoff for practicing surgery without a license.
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Manny Ares 👀 @mannyares.bsky.social · 14/10/2026
give us a link eh? ya hoser 🍁🥌🇨🇦
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Ben McAdams (The Resurrection Arc) @purrtah.bsky.social · 12/10/2026
A Susan Collins PAC bought ads in the wrong Portland and has been airing them in Oregon theintercept.com/2026/10/12/s...
theintercept.com
Susan Collins-Aligned Super PAC Buys Attack Ads in Portland... Oregon
The group Defending Main Street, long associated with Susan Collins, spent thousands attacking Troy Jackson in the wrong state.
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Ilhan Omar @ilhanmn.bsky.social · 12/10/2026
I’m ok. Make no mistake: this is an attempt to target political enemies and weaponize federal law enforcement. For ten years, Trump has targeted me with baseless lies and smear campaigns. This is just the latest escalation in his campaign of political intimidation. I will not be silenced.
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T Ferguson @tferguson2018.bsky.social · 10/10/2026
👀👀👀
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Cat Hicks @grimalkina.bsky.social · 11/10/2026
People just think science is bigger than it is because science has such unreal outcomes for our lives. There just aren't enough scientists, there isn't enough funding, there isn't enough time and there isn't enough resource for our needs. People think their countries fund it much more than they do
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News Eye @newseye.bsky.social · 11/10/2026
This is how you write a headline.
Telegraph headline:

Trump backstabs Zelensky for five minutes of midterm relief
Deal with Putin for Russia’s oil might soften the markets but Ukraine will pay the price
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ae @aelkus.bsky.social · 11/10/2026
this is mengele shit
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Shrew @shrewshrew.bsky.social · 10/10/2026
Mounting evidence that the labor powerful people seem to think AI will do is actually the administrative work, mental load, and institutional memory women have provided A helpmeet that knows all the answers (no) remembers to care for you (no) and isn't a bitch when you treat it badly (by design)
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Drug Monkey @drugmonkey.bsky.social · 10/10/2026
This is a great reminder for people interested in NIH grant selection that there are elements that are codified in the law by Congressional action. ecfr.io/Title-42/Par...
ecfr.io
42 CFR Part 52h | Scientific Peer Review of… | eCFR.io
Browse 42 CFR Part 52h: Scientific Peer Review of Research Grant… in the current eCFR, with source notes and navigation. Updated through Oct. 5, 2026.
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Jenny Chase @solarchase.bsky.social · 10/10/2026
Time for 2026 updates to my annual “opinions about solar” thread, now with storage. If you like these, you might like edition 2 of my book, Solar Power Finance Without The Jargon. A 30% discount code WSQ0437 is valid on publisher website til end of Nov 2026. www.worldscientific.com/worldscibook...
worldscientific.com
Solar Power Finance Without the Jargon
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Jason “Obstacle to Progress” Williams @jasonwilliamsny.bsky.social · 10/10/2026
I’m co-hosting a one-day visioning workshop on developing hands-on DNA sequencing experiences for public engagement and secondary school audiences in the U.K. if you or colleagues are interested share this link: docs.google.com/forms/d/e/1F...
docs.google.com
Sequencing for Everyone
Thank you for your interest in Sequencing for Everyone: Building a UK Network for Hands-on DNA Sequencing and Public Engagement, taking place on 24 November 2026, 9:00 AM–5:00 PM, at University Colleg...
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MwahahahahahadScientist @mads100tist.bsky.social · 09/10/2026
*typing furiously*
That scene from The Neverending Story where Atreyu is trying to save Artax that basically traumatized an entire generation of kids. Atreyu is labeled with 'ME' and Artax with 'THIS PAPER'
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Michael Hendricks 🇨🇦 @michaelhendricks.bsky.social · 09/10/2026
THERE IS NOTHING WRONG WITH THE PROJECT GRANT PROGRAM EXCEPT IT IS UNDERFUNDED. Breaking it, redesigning it, etc, cannot fix this.
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Stand Up for Science! @standupforscience.net · 08/10/2026
BREAKING NEWS: RFK Jr. to give 1.6M in CDC funds to allow his Danish friends to harm African babies in unethical trial. We will be launching ways to fight back in just a couple hours. GET IN, DORKS. We have an unethical study to stop! www.rollingstone.com/politics/pol...
rollingstone.com
CDC Is Moving Forward With a Previously Shelved Controversial Hepatitis B Vaccine Study
“It’s a wholly unethical trial, and it shouldn’t be allowed,” says Dr. Paul Offit of Guinea-Bissau study
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Manny Ares 👀 @mannyares.bsky.social · 09/10/2026
I did finally join the help group but they never got around to having a meeting.
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Peter Avellino @peterapeel.bsky.social · 08/10/2026
Walked by Walter Neff’s apartment in DOUBLE INDEMNITY this morning.
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