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Malcolm Macleod

@maclomaclee.bsky.social
588 followers 738 following 41 posts

Meta-researcher, Neurologist, Runner ... aspiring to get better at all these and more!

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Reposted by Malcolm Macleod
Nate @nateurneuro.bsky.social · 12/06/2026
This is one of those studies that I’m very glad was done and done well, and is also very fun to watch people be surprised by the results.
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Colby Vorland @colbyvorland.bsky.social · 05/07/2026
Yet another frustrating anecdote about trying to correct the scientific record academic.oup.com/jrssig/artic...
academic.oup.com
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Edinburgh Neuroscience @edinunineuro.bsky.social · 29/06/2026
This is us; this is Edinburgh Neuroscience! This newly commissioned video summarises our purpose and vision. 👇
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Edinburgh Neuroscience @edinunineuro.bsky.social · 29/06/2026
@cathyabbott.bsky.social @maclomaclee.bsky.social
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JMIR Publications @jmirpub.bsky.social · 18/06/2026
An estimated US$228 billion in biomedical research funding may be wasted every year. JMIR Metascience and Research Integrity is now accepting submissions for its first call for papers in its new section on Waste in Research. Learn more about it: metascience.jmir.org/announcements/…
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Ludo Waltman @ludowaltman.bsky.social · 18/06/2026
In this panel I will discuss some of the ideas developed in the RoRI Future of Peer Review report, to be published early next week! @rorinstitute.bsky.social @cwts.nl
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Cathy Abbott @cathyabbott.bsky.social · 22/05/2026
Exciting session filming for the new @edinunineuro.bsky.social website. Malcolm is saying “stay away from the socials Cathy Abbott” at this precise moment 🤭🤭🤭
Man in blue shirt surrounded by filming apparatus, huge pictures of neurons in the background
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Nick Brown @steamtraen.eu · 08/05/2026
It's now 4½ years since I first thought of writing it, and 3½ years since I actually started writing it, but today I finally got around to submitting the preprint. Say hello to SPIV. 🧵
SPIV analysis: A heuristic meta-method for detecting non-random patterns in study data
Nicholas J. L. Brown, PhD
Kyle Sheldrick, MD, PhD
Ben W. Mol, MD, PhD
Lyle C. Gurrin, PhD

Please address correspondence to nicholasjlbrown@gmail.com.

Abstract
The increasing prevalence of open data is changing the ways in which forensic meta-science is done. Previously it was possible to infer what had or had not taken place only by examining its published summary statistics. Today meta-researchers wishing to reanalyse published results can also examine author-supplied individual participant data (IPD) to identify irregularities, either because they are directly published or because an editor has asked the authors to supply them. Here, we discuss some of the ways in which one might go about trying to detect anomalies in typical datasets in the biomedical or social sciences by examining the relationship between consecutive participant records within a dataset. We refer to these as “SPIV analyses”, where SPIV stands for Sequences in Purportedly Independent Values. SPIV is based on the principle that the data records for consecutive participants in a randomized study — and, potentially, some study designs that do not use randomisation — should be independent of each other for the great majority of measured variables. Using SPIV techniques, we can identify data that do not satisfy this condition, perhaps as a result of having been falsified or generated manually by unscrupulous researchers.
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Lukas Röseler @aufdroeseler.bsky.social · 04/05/2026
Who do you review for? Should you boycott commercial publishers? Should you boycott specific publishers? Does it matter for your career? We are orgainizing a one-hour session with lightning talks and an open discussion. Join us on May 26th 12-13 CEST online. Registration at t1p.de/wdirf
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Zen Faulkes @doctorzen.net · 25/04/2026
If this topic in particular interests you, may I offer this blog post? neurodojo.blogspot.com/2026/04/nati...
neurodojo.blogspot.com
National Academies workshop on scientific integrity
I spent most of the day in a (probably ill-advised) attempt to provide a service to the online science community. I followed as much of day ...
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Simon is on strike ✊🏻 @simonxix.com · 20/04/2026
My previous research centre was among the highest performing in terms of REF at the university. It didn't stop senior management from gutting it. You can play their game perfectly, obey all their rules, and buy into their metrics... and still lose.
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Professor Caroline Edwards @theblochian.bsky.social · 30/03/2026
Theo Andrew: @edinburghdiamond.bsky.social complements Edinburgh UP by providing #OpenAccess via an experimental business model that established UPs struggle to adopt. Both approaches are needed & support one another #UKSG2026
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Rene Bernard @renebernard.bsky.social · 17/03/2026
Whether you are from Berlin or not, come & learn with us how to make your research transparent & reproducible! Join our free flipped classroom course in 5 online sessions (90 min each) starting April 2nd, 4 pm CET & get ECTS ! For more info and how to register, visit: tinyurl.com/reproteach
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Rene Bernard @renebernard.bsky.social · 14/03/2026
Today I presented at the fantastic @ecnp.eu workshop how the #eqipd framework connects to the skills you can leverage from preclinical Systematic Reviews. #ECNP #Neuroscience Slides are here: osf.io/pqja2/files/...
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Malcolm Macleod @maclomaclee.bsky.social · 14/03/2026
My slides for ECNP workshop today at osf.io/de6qh/files/... @ecnp.eu #ECNP
osf.io
OSF
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Edinburgh Neuroscience @edinunineuro.bsky.social · 11/03/2026
Aiden's story brings to fore the cutting-edge research taking place on living human brain tissue in Edinburgh. The generosity of patients facing stark and often terrifying diagnoses is hard to overstate. www.youtube.com/watch?v=4bT0...
youtube.com
Why a 28-year-old with brain cancer donated part of his living brain
YouTube video by CNN
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Chris Simms @chrisnsimms.bsky.social · 11/03/2026
This London Review of Books piece by Andrew O’Hagan is a wonderful read. I love this line: "Such pressure on a single mother was not to be sniffed at – and she had a plane to Verbier to catch." @lrb.co.uk www.lrb.co.uk/the-paper/v4...
lrb.co.uk
Andrew O’Hagan · Stay Classy: Mummy’s Favourite
With some people, money and sex are the only truths. It’s the ultimate delinquency to believe that gratification...
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Jennifer Byrne @jabyrnesci.bsky.social · 07/03/2026
Join us at #WCRI2026 for a networking session for anyone working on #PaperMills and #GenAI on the context of #ResearchIntegrity. There'll be lightning talks, networking and probs drinks/ dinner afterwards. May 4, 6.00-7.30 pm, all welcome!
media.tenor.com
a man wearing glasses and a black shirt that says may 4 on it
ALT: a man wearing glasses and a black shirt that says may 4 on it
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Malcolm Macleod @maclomaclee.bsky.social · 06/02/2026
I wrote a blog about scientific publishing for @edinunineuro.bsky.social ... blogs.ed.ac.uk/edneuro/2026... ... based on my @peerreviewcongress.bsky.social talk last year
blogs.ed.ac.uk
Does the Journal Article have a future? – Edinburgh Neuroscience
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Malcolm Macleod @maclomaclee.bsky.social · 18/12/2025
At base, AI can only tell you what is already knowable.
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Bernhard Voelkl @bernhardvoelkl.bsky.social · 18/12/2025
Gret talk by Berna Devezer @devezer.bsky.social at the reproducibiliTea Basel by @swissrn.bsky.social a case study on scientific rigor. Many thanks Berna -it was very illuminating. 👏
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Dementia Researcher @dementiaresearcher.bsky.social · 18/12/2025
Apply for up to £100k through the My Name's Doddie 2026 Catalyst Awards to support bold early stage MND research with potential to advance translation. www.dementiaresearcher.nihr.ac.uk/funding/mnd-...
dementiaresearcher.nihr.ac.uk
MND Catalyst Award - DEMENTIA RESEARCHER
Apply for up to £100k through the My Name's Doddie 2026 Catalyst Awards to support bold early stage MND research with potential to advance translation.
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Ronen Tamari @ronentk.me · 17/12/2025
'Civilizations die from suicide, not by murder.' (Toynbee)
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Dr Laura McCulloch @dr-l-mcculloch.bsky.social · 02/12/2025
We have a further exciting PhD opportunity in the lab investigating the impact of systemic infection on the recovering brain after stroke and its link to small vessel disease and cognitive decline. Details in the link below www.findaphd.com/phds/project...
findaphd.com
VIDA DTC - Understanding the impact of post-stroke infection on neuroinflammation and small vessel disease in stroke recovery at University of Edinburgh on FindAPhD.com
PhD Project - VIDA DTC - Understanding the impact of post-stroke infection on neuroinflammation and small vessel disease in stroke recovery at University of Edinburgh, listed on FindAPhD.com
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Florian Naudet @floriannaudet.bsky.social · 29/11/2025
🚨 Our team has just published a Registered Report in BMC Medicine, one of the very few medical journals that offers this format (if we want better science, we should not follow journal impact factors, we should support journals with the best policies).
link.springer.com
Efficacy and safety of esketamine for “treatment resistant depression”: registered report for a systematic review with an individual patient data meta-analysis of randomized, double-blind, placebo-con...
Background In 2019, the FDA and EMA approved intranasal esketamine for treatment-resistant depression (TRD). The current study re-evaluated its efficacy and safety. Methods This registered report pres...
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Darren Dahly @statsepi.bsky.social · 20/11/2025
Many thanks to everyone who has reached out publicly or privately in support of this work, especially those working in this field. Truly.
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Brian Nosek @briannosek.bsky.social · 19/11/2025
There is so much to be disappointed about in this story--from the institutional response to Miles Hewstone himself. We still have a lot of work to do to make academic environments inclusive spaces where everyone can thrive, and where harassers are held accountable.
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Malcolm Macleod @maclomaclee.bsky.social · 06/11/2025
Must be something in the Forth Valley water - knocking it out of the park at #healthawards25
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Jade Pickering, PhD @jadepickering.bsky.social · 28/10/2025
Highly recommend this opportunity! I was on the steering committee about 5-6 years ago and it was incredibly rewarding! (P.S. where did the years go?? 😵‍💫)
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World Conferences on Research Integrity @wcrifoundation.bsky.social · 27/06/2025
Abstract submission and travel grant application for the 9th World Conference on Research Integrity are open. Please consider to submit an abstract and to reshare this message. lnkd.in/eJ9hmaRs
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Wonkhe @wonkhe.bsky.social · 22/09/2025
NEW on Wonkhe: As universities rely increasingly on international fees, Daniel Sokol asks whether financial pressure is blinding institutions to a growing trade in deception buff.ly/YVffQG5
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DORA @dorassessment.bsky.social · 30/07/2025
"Who controls the scientific literature?" New guest blog post by @fionahutton.bsky.social, Damian Pattison and @drpeterrodgers.bsky.social explores the @elife.bsky.social model and the challenges of driving change in scientific publishing. Read it here 👉 sfdora.org/2025/07/30/s...
sfdora.org
Why are indexers unable to see that peer review can be more than a thumbs up or a thumbs down? | DORA
Journals and peer review are unlikely to change for the better if the companies that operate scientific indexes and citation databases continue to stifle innovation. At eLife we believe that the conte...
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PLOS @plos.org · 17/07/2025
Want to be part of the change to improve #research culture and practice? Join the Responsible Research in Action Unconference 2025 in Berlin, Sept 22-24 ⬇️ #ResponsibleResearch #ResponsibleResearchInAction #ResponsibleResearchPractice #RRiA
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Daniel Lakens @lakens.bsky.social · 08/07/2025
Do you want to go to a metascience conference where AI will not solve all problems, you can ask critical questions, and El$evier is not invited? Sign up for the mailing list for the 8th Perspectives on Scientific Error conference in 2026 in Leiden! perspectivesonscientificerror2026.wordpress.com
perspectivesonscientificerror2026.wordpress.com
PSE8
Visit the post for more.
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Peer Review Congress #PRC11 Coming 2029! @peerreviewcongress.bsky.social · 07/07/2025
The PRC program is now online! Scientific Retractions and #Democracy Index Scores Across 167 countries from ‪@choxos.bsky.social ‪@mcmasteruniversity.bsky.social is part of the #ResearchMisconduct and #ScientificIntegrity session Register at peerreviewcongress.org @bmj.com @jama.com
peerreviewcongress.org
International Congress on Peer Review and Scientific Publication
Enhancing the quality and credibility of science.
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Peer Review Congress #PRC11 Coming 2029! @peerreviewcongress.bsky.social · 02/07/2025
Meet The Peer Review Congress Plenary Speakers! ‪@maclomaclee.bsky.social of ‪@edinunineuro.bsky.social‬ and @edinburgh-uni.bsky.social‬ presents the Douglas G Altman Lecture September 4 Does the Journal Article Have a Future? Register at peerreviewcongress.org! @jama.com @bmj.com
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JBI @jbiebhc.bsky.social · 26/06/2025
Laura Boeira is at the #ESIC Cape Town Consensus Meeting on transforming #EvidenceSynthesis to improve lives. She gives an overview of Day 2 in a short video available at: evidencesynthesis.atlassian.net/wiki/spaces/... @wellcometrust.bsky.social
Connecting demand and supply side interest holders in evidence synthesis.
Evidence Synthesis Infrastructure Collaborative. Supported by Wellcome Trust.
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Colby Vorland @colbyvorland.bsky.social · 21/06/2025
A brief guide to statistical analysis of grouped data in preclinical research rdcu.be/er3HG
rdcu.be
A brief guide to statistical analysis of grouped data in preclinical research
Nature Metabolism - Clustering and nesting (C&N) arise in many preclinical studies, such as when animals are group-housed or share litters, or in cell culture. Ignoring C&N...
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Dementia Researcher @dementiaresearcher.bsky.social · 21/06/2025
Join Dr Arpan Mehta's lab at MRC PPU, Dundee, for a 12-month postdoc using CRISPR screens to explore ALS in iPSC-derived motor neurons. Closing date: 18th July www.dementiaresearcher.nihr.ac.uk/job/postdoc-...
dementiaresearcher.nihr.ac.uk
Postdoc Research Assistant: Mechanisms of the C9ORF72
Join Dr Arpan Mehta's lab at MRC PPU, University of Dundee, for a 12-month postdoc using CRISPR screens to explore ALS in iPSC-derived motor neurons.
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Brian Nosek @briannosek.bsky.social · 26/05/2025
An open letter highlighting the co-optation of open science language in the latest Executive Order to justify policies that are, in fact, antithetical to open science principles. Read and consider signing with your support. www.standupforscience.net/open-letter-...
standupforscience.net
Open Letter in Support of Science — STAND UP FOR SCIENCE
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James Thomas @jm-thomas.bsky.social · 19/05/2025
ICASR and DESTINY are holding a meeting in July! If you're interested in automation in evidence synthesis then do take a look - in person and online options available :) www.linkedin.com/feed/update/...
linkedin.com
Sign Up | LinkedIn
500 million+ members | Manage your professional identity. Build and engage with your professional network. Access knowledge, insights and opportunities.
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Lex Bouter @lexbouter.bsky.social · 08/05/2025
@jclinepi.bsky.social kindly invited me to express my thoughts on handling #ConflictsOfInterest of authors of scholarly publications. bit.ly/431UYIQ @nrin-integrity.bsky.social @opensciencenl.bsky.social @peerreviewcongress.bsky.social @davidit.bsky.social @lseimpactblog.bsky.social
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aRukon @arukon0.bsky.social · 09/05/2025
🔬 Transparent animal research is ethical, reproducible, and credible. Want to improve your lab's practices? Follow this 🧵 on the 10 essentials from the 𝐀𝐑𝐑𝐈𝐕𝐄 𝐆𝐮𝐢𝐝𝐞𝐥𝐢𝐧𝐞𝐬 #AnimalResearch #Transparency #ARRIVEguidelines #aRukon
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European Commission @ec.europa.eu · 08/05/2025
Choose Science. Choose Europe. A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open. With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond. Apply by 10 September → europa.eu/!fBTMgF
A graphic for the Marie Skłodowska-Curie Actions (MSCA), showing a historical portrait of Marie Skłodowska-Curie overlaid with an image of four young researchers walking down a hallway. The European Commission logo is in the top left. Text reads: "Marie Skłodowska-Curie Actions – €404.3 million to support postdoctoral researchers”
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simine vazire @simine.com · 08/05/2025
My editorial on how journals can earn trust. We often use journal names as proxies for quality. This is bad bc it’s not valid. But it could be. Editors could make journal name a valid signal. And we could place value on journals that show us how they do that. journals.sagepub.com/doi/full/10....
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Darren Dahly @statsepi.bsky.social · 08/05/2025
I'm not sure we needed a statistical test here folks.
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Réseau français de la recherche reproductible @reproductible-fr.bsky.social · 05/05/2025
Come learn how the @ukrepro.bsky.social evolved into a national network promoting open and reproducible research across 80+ institutions. Open to all researchers, support staff, and anyone interested in improving research culture! #UKRN #RFRR #Reproducibility #OpenScience #ResearchCulture
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Dan Quintana @dsquintana.bsky.social · 06/05/2025
Things that we cover: - How the concept of open science is not new - Whether the benefits of open science outweigh the extra time taken to implement these practices - The responsible development of open science practices in psychology - Data sharing considerations - Plus more!
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Amy Orben @orbenamy.bsky.social · 06/05/2025
I am so excited that this is now out. An absolutely **mammoth** amount of work, please give this thread a read ⬇️💪💪
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