Des mutations du gène TIE1 causent des lymphœdèmes primaires tardifs. Étude sur 755 patients par le Pr. Vikkula — UCLouvain, JCI 2024.

Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...