Vægttabsmedicin som Mounjaro og Wegovy giver typisk hurtige og store vægttab. Men uden en plan og løbende måling af kropssammensætningen

Objective This study tested the hypothesis that treatment with the glucagon-like peptide-1/glucagon receptor agonist SAR425899 would lead to a smaller decrease in sleeping metabolic rate (SMR; kiloc...

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Despite technological advances in metabolomics, large parts of the human metabolome are still unexplored. In an untargeted metabolomics screen aimi...

Ultra-weak ‘biophotons’ might be used to diagnose disease, or could even represent a new signalling mechanism in cells.

Appetite suppression by glucagon-like peptide-1 receptor agonists (GLP-1RAs) is thought to result from direct actions on neural circuits controlling food intake. In this article, we (1) propose that a shift in fuel partitioning toward fat oxidation caused by GLP-1RAs contributes to appetite suppression and (2) explore potential lines of research to test this hypothesis.

The NIH has recently called for expanding use of new approach methodologies (NAMs) to reduce use of animals in research. Arany discusses the need not to forget the irreplaceable aspects of animal rese...

Obesity and associated complications can be managed by obesity medications, prompting the revision of criteria for the diagnosis and staging of this disease.

Researchers are exploring why some individuals are naturally super-lean and may struggle to gain weight. The causes of such constitutional thinness offer clues to the physiology of weight control.

Researchers are exploring why some individuals are naturally super-lean and may struggle to gain weight. The causes of such constitutional thinness offer clues to the physiology of weight control.

Researchers are exploring why some individuals are naturally super-lean and may struggle to gain weight. The causes of such constitutional thinness offer clues to the physiology of weight control.

The mechanism and unique molecular/cellular features of the potent and selective AMPK inhibitor BAY-3827 are unraveled.

To the Editor: The review article by Fasano (Jan. 23 issue)1 concerning human nutrition and hunger regulation omits the crucial role of autophagy, a cellular recycling process vital for maintaining...

Objective The obesity epidemic, driven by a complex interplay of environmental and biological factors, remains a significant global health challenge. Herein, we investigate the impact of food insecu...

By centralizing previously dispersed datasets, we developed Adipose Tissue Knowledge Portal to integrate clinical and experimental results with transcriptomic and proteomic data from >6,000 women and ...

Vi foreslår at ’kropsstørrelse’ indføres på lige fod med ’handicap’ m.m. i Straffelovens § 266 b samt i ’Lov om forbud mod forskelsbehandling på arbej

It was a great and humbling honor to receive the 2016 Distinguished Career Award from my SSIB colleagues. This paper summarizes the major points of my DCA talk at the 2016 annual meeting. It is a refl...

Understanding the History, Drivers, and Future of the Obesity Epidemic in Children and Adolescents

To curb the obesity epidemic, it is imperative that we improve our understanding of the mechanisms controlling fat mass and body weight regulation. While g

G protein-coupled receptor 75 (GPR75) is emerging as a promising target for obesity treatment, but its exact role in energy regulation remains unclear. This article explores the latest research on GPR75’s molecular function, potential ligands, and therapeutic challenges in addressing obesity.

Morrison et al. show that the inhibition of ventromedial periventricular area (VMPeA) induces a state of thermoregulatory inversion (TI) in which thermogenic responses to cold ambient exposure are actively inhibited by an alternative thermoregulatory pathway via a dynorphinergic system. VMPeA is a switch for this novel thermoregulatory paradigm.