Physical activity improves health, yet the molecular mechanisms remain partially understood. This study presents a high-resolution, time-resolved atlas profiling 10,127 proteins across plasma, saliva,...

Peroxisomes execute essential functions in cells, including detoxification and lipid oxidation. Despite their centrality to cell biology, the relevance of peroxisomes to aging remains understudied. We...

This Review summarizes preclinical and clinical evidence highlighting the potential of incretin-based drugs as treatments of neurodegenerative diseases, such as Alzheimer’s disease or Parkinson’s dise...

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The Women’s Health Initiative has produced numerous influential findings

Blood glucose is one of the most essential parameters in metabolic research. Yet, accurate blood glucose monitoring in mouse models of diabetes is challenging due to the significant stress associated ...

openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.

For a long time, entering and succeeding in an academic career in the sciences has had a tacit requirement on top of all the explicit ones. It was no secret that you’d need to complete an undergrad…

Questions remain over whether further action will be taken after resignations and calls for the Tesla CEO to be expelled

La Conferencia de Rectores y el Consejo pactan con tres editoriales la renovación del acuerdo por el que sus investigadores pueden acceder a las publicaciones y dar a conocer sus trabajos, pero Elsevi...

Glutaric aciduria type-1 (GA1) is an inherited mitochondrial neurometabolic disorder with a poorly understood pathogenesis and unmet medical needs. GA1 can be diagnosed via its hallmark biochemical si...

The G1 and G2 variants of the APOL1 gene increase the risk of chronic kidney disease (CKD) in individuals of African descent. In the presence of secondary stressors such as inflammation and hypoxia, t...

El Centro de Investigaciones Interdisciplinares (Ci2A) arranca su actividad a partir del lunes en un megaedificio que ha permanecido 20 años vacío tras múltiples cambios de identidad, y mostramos por ...

Schneider Shorts 14.02.2025 – the Matthew Effect in Nobel retractions, Cambridge approves of papermilling, France rewards cheatery, with Karen and her mice, fake miRNA research in Canada, and…

The plasma membrane covering the primary cilium has a diverse accumulation of receptors and channels. To ensure the sensor function of the cilia, the ciliary membrane has higher cholesterol content th...