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Sable Systems

@sablesys.bsky.social
553 followers 924 following 409 posts

Thoughts, visions & revisions from John Lighton PhD, president & chief innovation officer of Sable Systems International (=the world's most advanced metabolic measurement systems)

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Sable Systems @sablesys.bsky.social · 26/09/2026
A great story of cellular & academic symbiosis (gift article) www.nytimes.com/2026/09/26/s...
nytimes.com
In an $80 Motel Room, a Discovery to Shed Light on the Origins of Life (Gift Article)
A scrappy science project led to a significant discovery: two new species of a rare organism that could elucidate a fundamental transition in the history of life on our planet.
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David Shiffman, Ph.D. 🦈 @whysharksmatter.bsky.social · 01/09/2026
A few countries are doing this. But I need to stress that it will only happen for a tiny fraction of US scientists who have lost funding or jobs. There are not enough jobs in the rest of the world combined. The impact of Donald Trump and Elon Musk will not be science moving, but less science. 🧪
nature.com
Canada recruits dozens of US scholars — including several science stars
US funding uncertainty was a key factor for several of the researchers heading to Canada. Observers predict more will follow.
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Sable Systems @sablesys.bsky.social · 27/08/2026
Predictable. (Gift link) www.nytimes.com/2026/08/27/w...
nytimes.com
Canada Hires U.S. Scholars From Harvard and Other Top Universities (Gift Article)
A crackdown on American academia by the Trump administration has handed Canadian universities a rare opportunity to lure some top researchers north.
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Sable Systems @sablesys.bsky.social · 24/08/2026
To our Canadian colleagues & friends (you know who you are): we support you in these difficult times. www.nytimes.com/2026/08/24/o...
nytimes.com
Opinion | Mark Carney Did What Canadians Elected Him to Do (Gift Article)
Mark Carney has chosen suffering, but he did what Canadians elected him to do.
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Jenna Norton @jenna-m-norton.bsky.social · 08/08/2026
NIH has lost more than 20% of its staff. NIH has lost 1 in every 5 workers. This undermines the NIH mission. @27unihted.bsky.social open.substack.com/pub/27unihte...
open.substack.com
Lost critical expertise is hindering the NIH mission
Concern 5 of the Bethesda Declaration: One Year Later
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Stand Up for Science! @standupforscience.net · 26/07/2026
Gutting federal research funding from America’s universities would not only dismantle the primary engine of scientific discovery in the United States, it would fundamentally change American science for generations to come. Article: zurl.co/sCa8E
zurl.co
Trump’s Plan for Science: More Money for A.I., Less for Universities
Michael Kratsios, President Trump’s science adviser, proposed overhauling how the government funds research. Democrats said Mr. Trump’s actions had weakened science.
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Scott MacFarlane @macfarlanenews.bsky.social · 13/07/2026
Nothing to see here: Just 292,150+ people warning about Trump Admin’s new federal rule to strip grant funding power away from experts, scientists and unbiased arbiters Instead granting power over federal grants to Trump appointees Enormous issue Comment deadline is today
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Gwen Pearson @bug-gwen.bsky.social · 13/07/2026
I encourage everyone who has submitted comments on the hot mess that is OMB-2026-0034 to also send a copy to your congress critters. www.theverge.com/science/9576...
theverge.com
The war against ‘woke’ could end US science as we know it
‘Everyone will be affected, not just scientists. Every community in the country.’
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Dovewoman 💙 🇺🇦 💙 @dovewoman.bsky.social · 10/07/2026
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Alex Wild @alexwild.bsky.social · 09/07/2026
Conservative ideology is rare at universities because it is an intellectual failure. It provides no useful insights and produces no technological advances. It failed. In the biggest free market for ideas ever created, the market chose the productive route of real scholarship and real research.
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Phil Plait @philplait.bsky.social · 09/07/2026
Short thread up and down
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Jacek Debiec, MD, PhD, DPhil 🌎 🧠 @drjacekdebiec.bsky.social · 08/07/2026
"Nobel-prize-winning chemist Omar Yaghi has left the United States for a full-time position at Tsinghua University in Beijing, China... In a recent interview with Scientific American, he said that the current state of US science is 'not so encouraging.'" #AcademicSky www.nature.com/articles/d41...
nature.com
Nobel-winning chemist leaves US to direct AI materials lab in China
Omar Yaghi’s move comes amid cuts to US science and a campaign in China to recruit top international talent.
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Mikel 🇺🇦 @mikelking.com · 02/07/2026
When stupidity is considered patriotism, it is unsafe to be intelligent. ~ Issac Asimov #ThoughtfulThursday
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Lawrence Kazak @kazaklab.bsky.social · 30/06/2026
We’re now at >100 registrants for the 2nd #AdiposeBiology Conference. #Earlybird deadline approaching fast: July 1, 2026. Join us in Montreal 🇨🇦 on Oct 7–9, 2026. 🔗 Register before the early bird deadline at: adiposebiology.com #ABC2026 @sablesys.bsky.social @adiposebiology.bsky.social
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Michael Kearney @ecophys.bsky.social · 14/12/2024
I'm happy to use my first #Bluesky post to announce that there's now a shiny app for the endotherm model of the #NicheMapR package bioforecasts.science.unimelb.edu.au/app_direct/e...
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Michael Kearney @ecophys.bsky.social · 29/06/2026
I'm looking for a postdoc to work on an Australian Research Council Laureate Project on climate change responses, applying a Julia implementation of the NicheMapR package. The work could go in control theory, DEB theory or population process directions unimelb.wd105.myworkdayjobs.com/UoM_External...
unimelb.wd105.myworkdayjobs.com
Research Fellow in Biophysical Ecology
Role type: Full Time (1.0 FTE); Fixed term for 2 years Faculty: Faculty of Science Department/ School: School of BioSciences Salary: Level A: $87,266 - $118,416 p.a. plus 17% super ARC-funded climate ...
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Christopher Mims @mims.bsky.social · 29/06/2026
so... yay? www.newscientist.com/article/2531...
newscientist.com
Remote-controlled cockroach swarm can now breathe underwater
Tiny 3D-printed diving suits allow cockroaches to walk underwater for up to 3 hours with no ill effects, which could enable a cyborg insect swarm to explore disaster zones and perhaps even Mars
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Kiran Soma @kiransoma.bsky.social · 21/06/2026
The Science That Turned Lizard Venom Into GLP-1s Is Under Attack www.nytimes.com/2026/06/20/o... Free 🎁 article.
nytimes.com
Opinion | The Science That Turned Lizard Venom Into GLP-1s Is Under Attack
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The Brian Lehrer Show @thebrianlehrershow.bsky.social · 16/06/2026
We tackled ultra-processed foods and how they affect our health in a three-part series today. First: @kevinh-phd.bsky.social, former senior investigator at the NIH discusses his groundbreaking study on how human bodies respond to ultra-processed foods. Take a listen: wnyc.org/browse/shows...
wnyc.org
What Are Ultra-Processed Foods and What Are They Doing to Us? | WNYC
Kevin Hall discusses his groundbreaking research tracking how bodies respond to ultra-processed foods.
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Sable Systems @sablesys.bsky.social · 14/06/2026
"As we enjoy great advantages from the inventions of others, we should be glad of an opportunity to serve others by any invention of ours; and this we should do freely and generously." -- Benjamin Franklin
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Sable Systems @sablesys.bsky.social · 13/06/2026
My comment on the USA Office of Management & Budget's proposal that unqualified political appointees be given life & death powers over scientific research grants that they do not & cannot understand:
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Seamus Blackley @seamus.bsky.social · 09/06/2026
Are you a build engineer? Want to get in on something fucking astounding? DM me. Last chance. I’m trying not to hire the usual suspects here. Be someone different and amazing. Hit me. Let’s go.
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Lawrence Kazak @kazaklab.bsky.social · 04/06/2026
Approaching 100 registrants for the #AdiposeBiology Conference! Due to popular demand, the early-bird deadline has been extended to July 1, 2026. Join us in Montreal 🇨🇦 | Oct 7–9, 2026 🔗Register before the early bird deadline: www.adiposebiology.com/registration #ABC2026 @sablesys.bsky.social
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Gregg Gonsalves @gregggonsalves.bsky.social · 03/06/2026
Holden Thorp is an institutionalist. He's been a university chancellor, provost, now EiC of Science. When institutionalists pull the fire alarm, we listen, because the call to action he issued this week exposes the dire nature of the threat we are facing. 1/ www.science.org/doi/10.1126/...
science.org
Another red alert for American science
Although research has bipartisan support in the US Congress, and trust in science is above 75% across the country, the Trump administration seems as determined as ever to mortally wound the nation’s s...
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Canadian Curmudgeon 🍁 @cdncurmudgeon.bsky.social · 03/06/2026
donmoynihan.substack.com/p/the-creep-... The Creep of Politicization A new assault on science highlights a broader pattern So how much worse can the new policy be? Scientists are using apocalyptic terms, like “the end of American science as we know it.”
donmoynihan.substack.com
The Creep of Politicization
A new assault on science highlights a broader pattern
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Carl T. Bergstrom @carlbergstrom.com · 03/06/2026
"Would someone from abroad want to come to the United States to start their career in science when the NAS Presidential address repeated the structural risks of America’s apparent ‘over-reliance on foreign researchers’?" What on earth is going on at the NASEM? @joshuasweitz.bsky.social reports.
joshuasweitz.substack.com
A Response to The National Academies' Vision for Science: Averting a Path Towards Mediocrity
On the National Academy of Sciences Presidential address & panel on 'The State of Science' - both what was said and the many things that were left unsaid.
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Physicians for a Healthy Democracy @physiciandemocracy.medsky.social · 02/06/2026
@catgyoung.bsky.social www.npr.org/2026/06/01/n...
A cancer vaccine, using the same core mRNA technology as the COVID vaccine, has shown an almost 50% reduction in the risk of melanoma recurrence or death when combined with immunotherapy.  This is why we fund mRNA technology.
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Annika Barber @annikabarber.bsky.social · 02/06/2026
Is it pronounced ORCID 🌸 like the flower or Orc ID 👹 like an identity card for a Middle Earth monster? Smart people disagree. Personally, I pronounce it Orc ID because I like the idea that I am a science goblin with a fixed numerical identifier. @orcid.org
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Katie Mack @astrokatie.com · 29/05/2026
It’s truly astonishing to see how comprehensively the US government is tearing down every part of the system that has made it up until now a world-leading power in science, research, and technological development. The entire world will suffer from this wanton destruction.
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Stand Up for Science! @standupforscience.net · 01/06/2026
Stand Up for Science Director of Policy @colesci.bsky.social breaks down the steps needed to put American Science back on the world pedestal after the Trump Admin's demolition of the scientific field. Read the article here: zurl.co/1ZCvE #Science #Trump #SaveScience #StandUpForScience
The graphic shows contains a recent photo of the White House. The graphic reads: "Tech Policy.PRESS: Perspective: How to Rebuild US Science and Technology Policy From the Rubble of Trump 2.0, by Cole Donovan, June 1, 2026".
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Michael D. Green, PhD @michaeldgreen.phd · 28/05/2026
President of MIT not mincing words today in @statnews.com www.statnews.com/2026/05/27/s...
So let me say it as clearly as I can: Without basic scientific research, supported by the kind of farsighted public investment that allows large-scale, undirected, curiosity-driven inquiry, the scientific pipeline will run dry.
In daily life, people may not feel the effects right away, or even in 10 years. But we will feel it. And when someone we love needs therapies that could have emerged but didn't or when other countries now
investing in science can launch new science-based industries or run their societies on vast resources of fusion energy or reap the benefits of quantum computing power or advanced medical breakthroughs, America will wish it sustained its leadership in scientific research here and now.
Sally Kornbluth is the president of MIT.
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Lawrence Kazak @kazaklab.bsky.social · 25/05/2026
Don’t miss the @adiposebiology.bsky.social Conference in Montreal 🇨🇦 | Oct 7–9, 2026! 🔗#Earlybird deadline approaching fast: June 1, 2026 adiposebiology.com Join leaders in adipose biology, #metabolism, #obesity, #diabetes, #thermogenesis, & #development #ABC2026 @sablesys.bsky.social
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Jason Rasgon @vectorgen.bsky.social · 22/05/2026
This is fucking insanity www.insidehighered.com/news/quick-t...
insidehighered.com
Report: NIH, NASA Restrict Co-Authoring With Foreign Scientists
The National Institutes of Health and the National Aeronautics and Space Administration are targeting collaborations between U.S. scientists and foreign researchers, Science reports.
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Steve Portugal @sjportugal.bsky.social · 19/05/2026
Our new paper is out in @jexpbiol.bsky.social - about metabolic acclimation to captivity in mole rats (photo by D Kleynhans). You can read it here - journals.biologists.com/jeb/article/.... Males and females respond differently to captivity!
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Andreas Nord @cyanistesnord.bsky.social · 15/05/2026
This study was led by soon-to-graduate PhD student #ElinPersson @biologylu.bsky.social with important contributions by @mariaagc.bsky.social at @uniofjyvaskyla.bsky.social. As always, @sablesys.bsky.social instruments made the work far easier.
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Tyler King @tyleraking.com · 09/05/2026
This website shows you what your browser is leaking about you. sinceyouarrived.world/taken
sinceyouarrived.world
taken.
A web page that tells you what your browser gave away the moment you arrived. No login, no form, no permission. Most pages do this. None of them tell you.
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Sable Systems @sablesys.bsky.social · 09/05/2026
Well, I guess these days the Do Not Call registry means nothing 🤣 several scan loan offers per day - each immediately reported as spam to @TMobile but they keep pouring in 🙄
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Sable Systems @sablesys.bsky.social · 05/05/2026
Just a normal day at Sable Systems International
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Sable Systems @sablesys.bsky.social · 04/05/2026
I really miss Dave...
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Lawrence Kazak @kazaklab.bsky.social · 04/05/2026
Speaker Spotlight: Aaron Cypess Join us for the 2nd annual #AdiposeBiology Conference in Montreal🇨🇦, Oct 7-9, 2026, to hear from this world expert in human BAT! Register before the early bird deadline at: adiposebiology.com #ABC2026 @mcgillgci.bsky.social @sablesys.bsky.social sys.bsky.social
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Adipose Biology Conference @adiposebiology.bsky.social · 04/05/2026
🚨 Don’t miss #ABC2026! ⏳ Early Bird ends June 1! last chance for the best price (group discounts available 👥) Join us in Montréal 🇨🇦 (Oct 7–9) for cutting-edge adipose biology research 🧠🔥 🎟️ adiposebiology.com @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social @sablesys.bsky.social
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Phil @philburns.bsky.social · 03/05/2026
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Phillip White @phillipjwhitephd.bsky.social · 01/05/2026
Listening to Erika and Scott give back-to-back Sable Award lectures was an amazing way to bring METPHYS2026 to a close! So glad to be able to celebrate the people making waves in the metabolism community with our partners @sablesys.bsky.social
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Eric Topol @erictopol.bsky.social · 29/04/2026
How to terminate >100 science US advisory committees. The unremitting path of destruction www.nature.com/articles/d41...
nature.com
Key US science panels are being axed — and others are becoming less open
A Nature analysis shows that the Trump administration has terminated more than 100 advisory committees to science agencies — and reduced the transparency and independence of those that remain.
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Sable Systems @sablesys.bsky.social · 29/04/2026
How about that. A post of mine reached an @medium digest. medium.com/@JohnLighton...
medium.com
A Simple, Elegant Method for Measuring Energy Allocation
Let’s talk about energy allocation, also known as energy partitioning! We’ll concentrate on animals that control their body temperature…
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Saganism @sagan.bsky.social · 25/04/2026
“We've arranged a society based on science and technology, in which nobody understands anything about science and technology. And this combustible mixture of ignorance and power, sooner or later, is going to blow up in our faces.” ― Carl Sagan
Carl Sagan speaking in front of microphones, Balck and White photo
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Sable Systems @sablesys.bsky.social · 21/04/2026
Great news! We still have a couple of seats left for our highly rated advanced metabolic phenotyping course! Move quickly & attend this stimulating introduction to getting the best possible science from your experimental animals. Carpe diem, stat! 🧪 www.sablesys.com/high-resolut...
sablesys.com
High-Resolution Metabolic and Behavioral Phenotyping Course
The high-resolution metabolic and behavioral phenotyping course will teach participants how to use Promethion Core for rodent metabolic and behavioral phenotyping.
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Ignacio Gallup-Diaz @igallupd.bsky.social · 19/04/2026
"Pancreatic cancer mRNA vaccine shows lasting results in an early trial: Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later."
nbcnews.com
Pancreatic cancer mRNA vaccine shows lasting results in an early trial
Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.
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Sylvain Giroud @sgiroud.bsky.social · 18/04/2026
Consider attending the American Society of Mammalogist (ASM) Meeting at Norfolk this summer (June 12-15) and Join the symposium co organized by Jessica LaPrice & myself on flexible and inflexible responses in heterothermic species. This will be a fun symposium! mammalmeetings.org/program/symp...
mammalmeetings.org
Symposia
Flexible vs. Programmed? Responses to Environmental Extremes in Mammalian Heterotherms Date: TBD Time: TBD Location: TBD Speakers: Austin Allison, Mallory Ballinger, Malcolm Reimer, Cory Williams T…
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Sable Systems @sablesys.bsky.social · 16/04/2026
#Irisin, an #exercise-induced #myokine, counters #obesity via effects on #adipose tissue — but how? With help from Promethion #Metabolic Cages, a Nature #Metabolism study has shown that irisin modulates adipose #IL33 levels to increase #thermogenesis. 🧪 www.nature.com/articles/s42...
nature.com
Defining the vascular niche of human adipose tissue across metabolic states - Nature Metabolism
An atlas highlights the heterogeneity of adipose tissue vasculature, identifies distinct endothelial subpopulations and provides insights into their contributions to metabolic disease.
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