Inositol pyrophosphates are conserved signaling molecules synthesized by the bifunctional PPIP5K enzymes, but how their cellular functions diversify across species remains poorly understood. Here, we ...

The kinetochore--the molecular machine that couples chromosomes to spindle microtubules--performs an essential, tightly regulated function, yet varies dramatically across eukaryotes. Microtubules are ...

During gastrulation, embryonic epithelia undergo large-scale remodelling to internalise the mesoderm. Whether the cellular mechanisms underlying these tissue deformations are conserved across species ...

A quantitative description of budding yeast polarization derived from live cell imaging enables systematic comparison of polarization phenotypes, revealing varying degrees of variation in physical cha...

A quantitative description of budding yeast polarization derived from live cell imaging enables systematic comparison of polarization phenotypes, revealing varying degrees of variation in physical cha...

Cells are the fundamental units of life, shaped by evolution into a remarkable diversity of forms and functions. Much is known about the roles of genes and proteins, the regulation of molecular proce…

Process ontology proposes that biological systems are best understood as composed of dynamic processes rather than static components. However, application to concrete research practice has remained c...

Process ontology proposes that biological systems are best understood as composed of dynamic processes rather than static components. However, application to concrete research practice has remained c...

Since the advent of molecular biology, research in cell biology has been strongly focused on identifying specific genes and proteins responsible for cellular phenomena. However, it is increasingly rec...

Functional defects resulting from deleterious mutations can often be restored during evolution by compensatory mutations. Importantly, this process can generate the genetic diversity seen in networks ...

Cell polarity is a crucial biological process essential for cell division, directed growth, and motility. In Saccharomyces cerevisiae, polarity establishment centers around the small Rho-type GTPase C...

Cells are the fundamental units of life, shaped by evolution into a remarkable diversity of forms and functions. Much is known about the roles of genes and proteins, the regulation of molecular proce…

Cells are the fundamental units of life, shaped by evolution into a remarkable diversity of forms and functions. Much is known about the roles of genes and proteins, the regulation of molecular proce…

Cdc42 is a Rho-family GTPase conserved across eukaryotes, where it plays essential roles in cell polarization. In single-celled yeast systems, Cdc42 is a key driver of symmetry breaking and polarized ...

In a world of zero-sum thinking, the EU's win-win logic can be a powerful tool.

The very short version: it is madness to continue transferring the running of European societies and governments to American clouds. Not only is it a terrible idea given the kind of things the “King o...

In Europa: Caroline de Gruyter

Thea Beckman: Op de barricaden stond ze niet, maar de ‘saai’ levende kinderboekenschrijfster belichaamde het feminisme, aldus haar biografie. Die toont hoe boeken jonge levens kunnen beïnvloeden.

WOinActie is een beweging van studenten en medewerkers en maakt zich sterk voor de universiteit en haar toekomst.