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Sajjita Saha

@sajjitasaha.bsky.social
107 followers 204 following 2 posts

Graduate Student @SophieMartin Lab 🧬🔬🧫@UniversityofGeneva | Hobby Pianist🎹 | Art enthusiast 🎨|

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Reposted by Sajjita Saha
Sophie G Martin @sophiemartinlab.bsky.social · 14h
Happy to share our latest work showing that fungal cell fusion not only requires local cell wall digestion but also inhibition of cell wall repair! PAK-family kinases promote cell fusion irreversibility by preventing cell-wall repair doi.org/10.1016/j.cu... Led by @juliacoronasserna.bsky.social
Post-fusion pak2 mutant cells with narrow fusion pore blocked by a vacuole
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Sajjita Saha @sajjitasaha.bsky.social · 21/03/2026
Happy to see our work out in PLOS Biology. Thanks to @sophiemartinlab.bsky.social @aiswaryasajeevan.bsky.social Laura Merlini & Vincent Vincenzetti. 😊
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Reposted by Sajjita Saha
Sophie G Martin @sophiemartinlab.bsky.social · 17/03/2026
Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast The work from Alejandro Melero @ameleroc.bsky.social and Miguel Basante-Bedoya just out in Current Biology. www.sciencedirect.com/science/arti... @biology-unige.bsky.social
sciencedirect.com
Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast
Endosomes serve as crucial sorting centers that streamline the distribution of cell surface proteins. The early endosome receives traffic from both th…
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Reposted by Sajjita Saha
Sophie G Martin @sophiemartinlab.bsky.social · 03/03/2026
You are finishing your PhD and looking to continue in science? The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro.... Thanks for reposting!
mocel.unige.ch
Contact/Job - Department of Molecular and Cellular Biology - UNIGE
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Reposted by Sajjita Saha
Sophie G Martin @sophiemartinlab.bsky.social · 25/09/2025
Super excited that this story by @borissieber.bsky.social is now on BioRxiv! For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it ! See the thread 👇 and enjoy the paper! doi.org/10.1101/2025...
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Reposted by Sajjita Saha
Sophie G Martin @sophiemartinlab.bsky.social · 06/05/2025
The lab is on a roll. 2nd preprint in as many weeks! High levels of Cdc42 GTPase underlie an all-or-none decision to fuse. Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social www.biorxiv.org/content/10.1... @biology-unige.bsky.social
biorxiv.org
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse
Cdc42 is a Rho-family GTPase conserved across eukaryotes, where it plays essential roles in cell polarization. In single-celled yeast systems, Cdc42 is a key driver of symmetry breaking and polarized ...
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Reposted by Sajjita Saha
Sophie G Martin @sophiemartinlab.bsky.social · 02/05/2025
New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction. A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social! www.biorxiv.org/content/10.1...
Schematics of the actin fusion focus
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