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Liam Browne

@liamebrowne.bsky.social
87 followers 91 following 6 posts

Associate Professor at UCL interested in pain and threat. Investigating cortical mechanisms and neural interfaces for chronic pain. browne-lab.github.io

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Reposted by Liam Browne
Sainsbury Wellcome Centre @sainsburywellcome.bsky.social · 21/09/2026
Applications are now open for the SWC Systems Neuroscience PhD Programme. Join us in London! 🎓 World-class neuroscience training 💰 Fully funded 4-year programme 🖥️Close links to @gatsbyucl.bsky.social Apply by 9 Nov: www.sainsburywellcome.org/web/content/...
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Liam Browne @liamebrowne.bsky.social · 07/09/2026
📣 Updated application link for the postdoc in my lab at UCL. A great opportunity to develop neurotechnology for chronic pain using neural implants, in vivo recordings, and adaptive control in mice. Applications are open now - please repost/share widely. #neuroskyence #painresearch #NeuroJobs
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Enny van Beest @ennyvb.bsky.social · 04/09/2026
Textbook: tracking position during navigation is primarily the job of the hippocampus. Recent findings suggest a more complicated story. Recording >20k neurons brainwide, we indeed find spatial representations in every region! With @kenneth-harris.bsky.social and @carandinilab.net
Brainwide representations of a virtual corridor
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araschorscherpetcu.bsky.social @araschorscherpetcu.bsky.social · 21/08/2026
Pleased to share our new preprint showing: 1/ how somatosensory cortex combines mechanical information, arousal, and movement at the population level. 2/ that the geometry of this population reconfigures during inflammatory pain and protective behavior. www.biorxiv.org/content/10.6...
biorxiv.org
A stimulus–state geometry in somatosensory cortex reorganizes during inflammatory pain
Adaptive behavior requires external input to be interpreted together with internal state and ongoing behavior. During pain, noxious somatosensory input evokes movement and arousal, and injury reshapes...
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Liam Browne @liamebrowne.bsky.social · 19/08/2026
Our new preprint identifies an injury mode in somatosensory cortex: inflammation reorganises population geometry, binding the dominant state axis more tightly to protective movement.
biorxiv.org
A stimulus-state geometry in somatosensory cortex reorganizes during inflammatory pain
Adaptive behavior requires external input to be interpreted together with internal state and ongoing behavior. During pain, noxious somatosensory input evokes movement and arousal, and injury reshapes...
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 17/08/2026
A stimulus-state geometry in somatosensory cortex reorganizes during inflammatory pain www.biorxiv.org/content/10.64898/20…
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Matteo Carandini @carandinilab.net · 13/07/2026
My home institute, @ucleye.bsky.social, is looking for a new Director! www.veredus.co.uk/job/job-1183a/
veredus.co.uk
Director of the UCL Institute of Ophthalmology - REF 1183 | Veredus
University College London Director of the UCL Institute of Ophthalmology  Location: London Salary: An attractive remuneration package UCL is a world leading, global university with a community of more...
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Liam Browne @liamebrowne.bsky.social · 06/07/2026
📣 We're hiring a postdoc in my lab at UCL! Help develop closed-loop neurotechnology for chronic pain by combining long-term neural implants and recordings with real-time adaptive control in mice. Closes 24 July — please repost or share widely.
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Reposted by Liam Browne
Stéphanie C Koch @skochlab.bsky.social · 30/04/2026
Our paper is out! Work by Christopher Black in collaboration with Liam Browne, Rob Brownstone, and Marco Beato. Here, we describe the unique kinematic signatures of multi-limb coordination in freely climbing mice and show how these flexibly adapt to changing environments. tinyurl.com/4bnw88wk
tinyurl.com
Naturalistic climbing reveals adaptive strategies for interlimb coordination in freely moving mice
Multi-limb coordination is vital for mammalian locomotion. While coordination requires reliable organization of limb movements, it also requires flexibility to adapt to environmental demands. In natur...
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Andrew MacAskill @macaskillaf.bsky.social · 26/04/2026
Huge congrats to @snierwetberg.bsky.social , David (not on BSky), and @maxwellxchen.bsky.social for their paper! They developed a mouse task in which relational structure can be isolated from cue identity and reward statistics. www.biorxiv.org/content/10.6... 🧠📈🧪 #neuroskyence @uclnpp.bsky.social
biorxiv.org
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Datta Lab @dattalab.bsky.social · 25/03/2026
Have you ever wondered why mice do what they do when they are free to do whatever they want? Check out our latest (and this slightly delayed thread about our recent paper, led by Caleb Weinreb and friends...) www.cell.com/neuron/fullt...
cell.com
Spontaneous behavior is a succession of self-directed tasks
Weinreb et al. reveal a hierarchy of timescales in mouse behavior, including low-level syllables and high-level behavioral states. States and syllables are encoded in different brain areas. Prefrontal...
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John Tuthill @tuthill.bsky.social · 24/03/2026
🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social We gave a worm brain control of a fly body and it walked What did we learn? Nothing, other than deep reinforcement learning is effective We call it the digital sphinx www.biorxiv.org/content/10.6...
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Sophie Acton @actonlab.bsky.social · 02/03/2026
*Recruiting new group leaders* The @lmcb-ucl.bsky.social at University College London are looking for outstanding candidates to sponsor for career development fellowships. Fellows would then be assessed for tenured positions at the end of the fellowship term.
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Matteo Carandini @carandinilab.net · 12/11/2025
Our lab is looking for a postdoc! We have interesting projects and cutting-edge techniques such as Neuropixels Opto, Light Beads Microscopy and more. We would be delighted to receive your application. Deadline is 25 November 2025. More info here: www.ucl.ac.uk/cortexlab/po...
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Niko Massaly @massalyniko.bsky.social · 22/10/2025
🚨 Please RT! We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain. Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged. Apply 👉 recruit.apo.ucla.edu/JPF10647 #Neuroscience #Postdoc
recruit.apo.ucla.edu
Postdoctoral Research Position
University of California, Los Angeles is hiring. Apply now!
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Ardem Patapoutian @ardemp.bskyverified.social · 14/10/2025
During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost! apply.interfolio.com/174756
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Ewan St. John Smith @psalmotoxin.bsky.social · 14/10/2025
If evolution, comparative #neuroskyence & #PainResearch are your thing, here's a great review from Terry Walters: journals.biologists.com/jeb/article/...
journals.biologists.com
From nociception in aneural animals to human suffering: toward a comparative biology of pain
Summary: The biology of widely shared and unusual features of human pain is informed by functional and mechanistic comparisons of nociception and pain-like aversive states across vertebrate and invert...
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Siri Leknes @sirileknes.bsky.social · 07/10/2025
One week left to apply!
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 01/10/2025
Lots of exciting clinical PhD projects at Crick - including the opportunity for neurosurgeons to work with us and record electrical activity in patients with neuropixels probes. Please share widely!
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Ben Seymour @benosaka.bsky.social · 01/10/2025
We are proud to launch what we think is going to be fantastic opportunity for pain neuroscientists and clinicians to learn the foundations of pain neuroscience
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Stéphanie C Koch @skochlab.bsky.social · 19/09/2025
New preprint out from the lab. We identified three critical windows over which sensorimotor behaviours can be shaped. Altered early experience over these windows changes somatosensory and motor outcomes for life. Tour de force experiments by Laura Andreoli. @medresfdn.bsky.social @uclnpp.bsky.social
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Ben Seymour @benosaka.bsky.social · 01/09/2025
We're looking for a senior project coordinator in Oxford - apply by friday eng.ox.ac.uk/jobs/job-det...
eng.ox.ac.uk
Job Detail
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Steve Middleton @middletonsj.bsky.social · 21/08/2025
We've found a new gene linked to chronic pain in humans! The gene SLC45A4 encodes (the long-awaited) neuronal polyamine transporter, which is important for pain signalling in nerves. We hope this discovery might lead to new chronic pain treatments in the future! www.nature.com/articles/s41...
nature.com
SLC45A4 is a pain gene encoding a neuronal polyamine transporter - Nature
The SLC45A4 gene encodes a neuronal polyamine transporter and is linked to pain response in humans and mice.
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Miriam Klein-Flügge 🧠 @mkflugge.bsky.social · 20/08/2025
We are super excited about the first human transcranial ultrasound study from our lab which is now on BiorXiv, showing the amygdala‘s role in processing ambiguous emotions and showing TUS changed resting-state connectivity and metabolite concentrations (GABA) in the amygdala - a huge team effort! 🥳🙏🏼
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Blake Richards @tyrellturing.bsky.social · 11/07/2025
1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex: www.biorxiv.org/content/10.1... I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction. But... 🧠📈 🧪
biorxiv.org
Sensory responses of visual cortical neurons are not prediction errors
Predictive coding is theorized to be a ubiquitous cortical process to explain sensory responses. It asserts that the brain continuously predicts sensory information and imposes those predictions on lo...
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Sainsbury Wellcome Centre @sainsburywellcome.bsky.social · 05/06/2025
Calling all neuroscience postdocs! Come and share your work with the London neuroscience community. No CVs, publication records or recommendation letters needed. Learn more about SWC’s Emerging Neuroscientists Seminar Series and apply by 10 July: www.sainsburywellcome.org/web/content/...
Quote: "The community of neuroscientists is so incredible at SWC, and I wanted to come and share my work and ideas with them." Christopher Zimmerman, 2024 ENSS Speaker
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Ole Kiehn @olekiehn.bsky.social · 28/05/2025
Excited to present our study in ‪@natneuro.nature.com‬: a deep brain pathway that triggers safety-driven movement—overriding needs like finding food or social contacts. A look into how the brain weighs deep instincts. Congrats to all and first author @nkrauth.bsky.social. shorturl.at/toYFN
shorturl.at
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs - Nature Neuroscience
Animals need to adapt behavior to balance survival with fulfillment of essential needs. Krauth et al. identify neurons in the lateral hypothalamus that, when activated, prioritize survival over other ...
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⚡️GREG_CORDER⚡️ @flybottleescape.bsky.social · 26/05/2025
🧠 🍄 ⚡️🐭 Now published in @natneuro.nature.com Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility nature.com/articles/s4159…
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Datta Lab @dattalab.bsky.social · 09/05/2025
Maps are everywhere in the brain...and finally we've discovered one in the nose! Led by @davidhbrann.bsky.social, we uncovered the logic that specifies the positions of each of the 1,000 sensory neuron subtypes in the nose and aligns their projections to the brain.👇👃see more details below👃👇
biorxiv.org
A spatial code governs olfactory receptor choice and aligns sensory maps in the nose and brain
Although topographical maps organize many peripheral sensory systems, it remains unclear whether olfactory sensory neurons (OSNs) choose which of the ~1100 odor receptors (ORs) to express based upon t...
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Andreas Schaefer @andreas-t-schaefer.bsky.social · 01/05/2025
Linking function and structure at scale with X-rays - and several times over. Massive congratulations to the team ‪@yuxinzhang.bsky.social‬, @carlesbosch.bsky.social, @apacureanu.bsky.social @esrf.fr, @crick.ac.uk and all our collaborators.
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Liam Browne @liamebrowne.bsky.social · 15/04/2025
We've developed a way to remotely and precisely activate skin sensory neurons in mice as they naturally explore and navigate their environment - opening doors for studying sensation, behaviour, and pain in naturalistic settings. Now out: shorturl.at/ry4s9 #neuroskyence #neuroscience #PainResearch
elifesciences.org
Precision cutaneous stimulation in freely moving mice
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Aman Saleem @amansaleem.bsky.social · 14/04/2025
2. Systems Neuroscience PhD position, supervised jointly with Sarah Ruediger @ruedigersarah.bsky.social This is to investigate the differential circuits involved in habitual and goal-directed behaviours. www.findaphd.com/phds/project...
findaphd.com
Systems Neuroscience PhD at UCL at University College London on FindAPhD.com
PhD Project - Systems Neuroscience PhD at UCL at University College London, listed on FindAPhD.com
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Aman Saleem @amansaleem.bsky.social · 14/04/2025
1. Project on Computational Neuroscience / NeuroAI PhD, supervised jointly with Caswell Barry @caswell.bsky.social Here we want to build NeuroAI models that transform visual information to spatial navigation information. www.findaphd.com/phds/project...
findaphd.com
Computational Neuroscience, NeuroAI PhD at UCL at University College London on FindAPhD.com
PhD Project - Computational Neuroscience, NeuroAI PhD at UCL at University College London, listed on FindAPhD.com
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Ann Clemens @annmclemens.bsky.social · 09/04/2025
New preprint ✍️🚨 ✨Ontogeny of tactile, vocal and kinship dynamics in rat pup huddling -Huddle dynamics develop w/o kinship selectivity -Vocal/internal-state quiets w/ huddling & kin/ touch in yng pups tinyurl.com/y7vhkwjc 👏 @flor-bela.bsky.social @hughtakemoto.bsky.social @kinshiplab.bsky.social
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Stéphanie C Koch @skochlab.bsky.social · 08/04/2025
Last few days to apply to come work with our team- deadline 11th April. See details below.
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Stéphanie C Koch @skochlab.bsky.social · 06/04/2025
New preprint out! We developed a behavioural platform for the kinematic analysis of skilled whole body behaviour. Very fun collaboration with Christopher Black, @liamebrowne.bsky.social and Rob Brownstone.
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Patrik Ernfors @patrikernfors.bsky.social · 24/03/2025
How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study. www.nature.com/articles/s41...
nature.com
Neural ensembles that encode nocifensive mechanical and heat pain in mouse spinal cord - Nature Neuroscience
Zhang et al. identify unimodal neural representations in the spinal cord of cutaneous mechanical and heat stimuli gated by a shared feed-forward local inhibitory neuron type and a neural transition du...
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Bence Ölveczky @olveczky.bsky.social · 04/03/2025
Excited to present the latest from the lab out today in Cell www.cell.com/cell/fulltex.... See Thread! 1/8
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⚡️GREG_CORDER⚡️ @flybottleescape.bsky.social · 26/02/2025
On behalf of my BSky-less student, Lisa Wooldridge: 🐭🧠💊⚡️ "Thrilled that my PhD work is on bioRxiv! I study how central amygdala (CeA) neurons contribute to opioid effects, but how specific CeA cell types drive this process remains unclear" 🧵 www.biorxiv.org/content/10.1...
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Niccolò Zampieri @niccolozampieri.bsky.social · 14/02/2025
🥁 Elisa Toscano idenitified a new subtype of propriospinal neurons and found a role in the execution of skilled movements🤸‍♂️. Great job from Elisa and everybody involved 💪. @alesantuz.bsky.social, @lowensteined.bsky.social. Check it out and let us know what you think: www.biorxiv.org/content/10.1...
biorxiv.org
Identification of V0g propriospinal neurons and their role in locomotor control
Propriospinal neurons relay sensory and motor information across the spinal cord and are critical components of the circuits coordinating body movements. Their diversity and roles in motor control are...
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Matteo Carandini @carandinilab.net · 07/02/2025
Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)
A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.
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Earl K. Miller @earlkmiller.bsky.social · 03/02/2025
Sensory inputs trigger a fast-traveling wave, followed by a slower wave carrying top-down info (value/choice). The late wave reactivates ensembles in superficial cortical layers. Touch-evoked traveling waves establish a translaminar spacetime code www.science.org/doi/full/10.... #neuroscience
science.org
Touch-evoked traveling waves establish a translaminar spacetime code
Translaminar spacetime patterns organized by feedback-dependent cortical circuits support sparse traveling waves.
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Stéphanie C Koch @skochlab.bsky.social · 30/01/2025
Wondering about the sorts of pain research questions we ask in the lab? See this short video by the Medical Research Foundation on work they generously funded. A reminder that we have a postdoctoral position opening up in the next month! @ucllifesciences.bsky.social @ucl-neurodomain.bsky.social
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Tim Behrens @behrenstimb.bsky.social · 30/01/2025
Hope you'll forgive a quick thread as I take over as the new EiC of @elife.bsky.social
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Steve Fleming @smfleming.bsky.social · 28/01/2025
Thanks to all who came to support and watched online! A recording is available here: www.youtube.com/live/6LSfkQk...
youtube.com
How the human brain thinks about itself | The Royal Society
YouTube video by The Royal Society
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Oliver Robinson @olijrobinson.bsky.social · 27/01/2025
Come join us at the ICN. Were looking for an Associate or Full Professor: www.ucl.ac.uk/work-at-ucl/... (these jobs aren't advertised very often!)
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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