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Animals need to adapt behavior to balance survival with fulfillment of essential needs. Krauth et al. identify neurons in the lateral hypothalamus that, when activated, prioritize survival over other ...

Animals need to adapt behavior to balance survival with fulfillment of essential needs. Krauth et al. identify neurons in the lateral hypothalamus that, when activated, prioritize survival over other ...

Objective The obesity epidemic, driven by a complex interplay of environmental and biological factors, remains a significant global health challenge. Herein, we investigate the impact of food insecu...

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To curb the obesity epidemic, it is imperative that we improve our understanding of the mechanisms controlling fat mass and body weight regulation. While g

Douglass et al. employ long-term, continuous fiber photometry to uncover new modes of agouti-related peptide (AgRP) neuron regulation in ad libitum, fasted, and circadian conditions. AgRP neuron activity exhibits a circadian rhythm, which controls daily feeding patterns through a neural circuit from the suprachiasmatic nucleus via the dorsomedial hypothalamus.

Animals continously adapt their behavior to balance survival and fulfilling essential needs. This balancing act involves prioritization of safety over the pursuit of other needs. However, the specific...