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Models and interventions of cognition.

Editorial Information | Minds, Machines, and Brains | MIT Press Editorial Information All inquiries should be directed to mindsmachinesandbrains@gmail.com Co-Editors in Chief Leyla Isik ...

The ability to seek reward and avoid punishment is a fundamental survival instinct. In natural environments, however, the statistics of rewards and punishments can change independently of one another....

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Career Development Research Fellowship in Psychology for full-time research offered by St John’s College to early career researchers who have recently completed or are close to completion of a doctora...

Career Development Research Fellowship in Psychology for full-time research offered by St John’s College to early career researchers who have recently completed or are close to completion of a doctora...

Value-based decision-making can be conceptualized as navigation within a cognitive map of choice values. During choice, the ventromedial prefrontal cortex (vmPFC) compositionally builds cognitive maps...

Spatial attention supports navigation by prioritizing information from selected locations. A candidate neural mechanism is provided by theta-paced sweeps in grid- and place-cell population activity, which sample nearby space in a left-right-alternating pattern coordinated by parasubicular direction signals. During exploration, this alternation promotes uniform spatial coverage, but whether sweeps can be flexibly tuned to locations of particular interest remains unclear. Using large-scale Neuropixels recordings in freely-behaving rats, we show that sweeps and direction signals are rapidly and dynamically modulated: they track moving targets during pursuit, precede orienting responses during immobility, and reverse during backward locomotion — without prior spatial learning. Similar modulation occurs during REM sleep. Canonical head-direction signals remain head-aligned. These findings identify sweeps as a flexible, attention-like mechanism for selectively sampling allocentric cognitive maps. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, Synergy Grant 951319 (EIM) The Research Council of Norway, Centre of Neural Computation 223262 (EIM, MBM), Centre for Algorithms in the Cortex 332640 (EIM, MBM), National Infrastructure grant (NORBRAIN, 295721 and 350201) The Kavli Foundation, https://ror.org/00kztt736 Ministry of Science and Education, Norway (EIM, MBM) Faculty of Medicine and Health Sciences; NTNU, Norway (AZV)

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When choosing between options with multiple attributes, the orbitofrontal cortex (OFC) is thought to integrate across those attributes, aiding in value comparisons. This study shows in monkeys that OF...

The Faraday Discovery Fellowships Accelerated International Route provides a fast-track option for attracting mid-career researchers looking to relocate to the UK from overseas, providing up to £4m ov...

A new Medical Research Council Centre of Research Excellence (MRC CoRE) aims to develop brain stimulation devices to treat conditions such as Parkinson’s, dementia, stroke and childhood epilepsy.

Available in Paperback from 9th November 2022

The Python interface to SPM. Contribute to spm/spm-python development by creating an account on GitHub.

Individual dopaminergic neurons encode future rewards over distinct temporal horizons.

Reinforcement Learning Mechanisms of Pharmacological Treatments for Depression (RELMED)

Complex behavior calls for hierarchical representation of current state, goal, and component moves. In the human brain, a network of “multiple-demand” (MD) regions underpins cognitive control. We reco...