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Quentin Huys

@docqhuys.bsky.social
2.7K followers 474 following 87 posts

Professor of Computational Psychiatry @UCL. www.acplab.org. CI of RELMED study relmed.bsky.social / relmed.ac.uk.

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Reposted by Quentin Huys
Sarah Yip @yiplab.bsky.social · 05/03/2026
Excited to share our latest paper in which we discuss merging theory-and data- driven computational psychiatry in a large transdiagnostic cohort study (N=2400) www.biologicalpsychiatrycnni.org/article/S245... Christopher Pittenger, Godfrey Pearlson @annierhcheng.bsky.social @sobp-org.bsky.social
biologicalpsychiatrycnni.org
Threading the needle: Practical considerations for merging theory-driven computational psychiatry with data-driven analytics to enhance precision health at scale
The rapidly evolving field of computational psychiatry enables quantification of specific cognitive processes, and their underlying mechanisms, in a translational and potentially scalable manner, usin...
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Quentin Huys @docqhuys.bsky.social · 06/03/2026
If you live in the UK, please consider filling this in to keep the BBC reporting truth in our world of lies: www.gov.uk/government/c.... And here are some suggestions regarding answers: britishbroadcastingchallenge.com/wp-content/u...
gov.uk
Britain’s Story: The Next Chapter - BBC Royal Charter Review, Green Paper and public consultation
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Yaniv Abir @yanivabir.bsky.social · 07/01/2026
Come work with us! really great team and super exciting project.
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Quentin Huys @docqhuys.bsky.social · 08/01/2026
The really exciting moments. Many congratulations Dr Chen! @jiazchen.bsky.social
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Quentin Huys @docqhuys.bsky.social · 21/12/2025
Postdoctoral research position in #ComputationalPsychiatry and #EEG as part of relmed.ac.uk trial testing reinforcement learning as biomarker for antidepressant treatment response. www.ucl.ac.uk/work-at-ucl/... @uclbrainscience.bsky.social @mikebrowning.bsky.social @relmed.bsky.social
relmed.ac.uk
Antidepressant treatment shouldn't be a guessing game. RELMED is working towards using advanced research to predict which medication is most likely to help each person along their individual path to recovery.
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Xiaosi Gu @xiaosigu.bsky.social · 21/11/2025
📣🔥Thrilled to announce that 2026 Computational Psychiatry Conference will take place in New Haven, CT, btw July 14-16 - www.cpconf.org @robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop More info to come soon!
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relmed.bsky.social @relmed.bsky.social · 27/10/2025
vimeo.com/1125505169?f... Are you: ✅ Aged 18 or over ✅ Experiencing depression or low mood ✅ Registered with a GP in England You may be eligible to take part in the RELMED Study, exploring ways to improve treatment for depression. 🎥 Watch our short introductory video to learn more!
vimeo.com
RELMED Introduction
RELMED is a research study focused on improving how we treat depression. To participate, visit RELMED.AC.UK for more information. CREDITS Actor: Ben Willbond Script:…
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Quentin Huys @docqhuys.bsky.social · 03/11/2025
New #neurojob #psychiatryjob #jobalert. www.northlondonmentalhealth.nhs.uk/current-vaca.... Focus is on clinical trials for mood disorders, with close links to @uclpsychiatry.bsky.social @uclqsion.bsky.social and @mpc-comppsych.bsky.social
northlondonmentalhealth.nhs.uk
Current vacancies
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Nature Computational Science @natcomputsci.nature.com · 10/10/2025
In a Comment, @docqhuys.bsky.social and Michael Browning argue that the field of computational psychiatry will improve patient outcomes through its increasing focus on interventions and trials. #mentalhealthresearch #Psychiatry ➡️ nature.com/articles/s43... 🔓 rdcu.be/eKp1v 🧵(3/8)
nature.com
Trials for computational psychiatry - Nature Computational Science
Computational psychiatry is increasingly delivering causal evidence by focusing on interventions research and clinical trials. Causal evidence could improve patient outcomes through improved precision, repurposing, novel interventions, scaling of psychotherapy and better translation to the clinic.
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relmed.bsky.social @relmed.bsky.social · 15/08/2025
Depression can affect the mind, body and daily life in ways you might not expect. 🧠Swipe to learn the key signs and symptoms – and why recognising them matters. #Depression #Mentalhealth #Research
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relmed.bsky.social @relmed.bsky.social · 24/09/2025
Curious about how scientists measure brain activity through EEG? Swipe to read more! ⚡️
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relmed.bsky.social @relmed.bsky.social · 10/10/2025
🧠🌍 On World Mental Health Day, we’re reminded that mental health is a global priority. RELMED is committed to developing evidence-based practices to improve how we treat depression. Thank you to all our participants and everyone who has contributed to research. Each voice truly makes a difference.
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Quentin Huys @docqhuys.bsky.social · 01/10/2025
New #job alert! Clinical research fellow / postdoc in #computationalpsychiatry at the @mpc-comppsych.bsky.social / @uclqsion.bsky.social and UCL psychiatry. We will aim to understand the computations engaged by serotonin in the treatment of depression. Please re-sky. www.ucl.ac.uk/work-at-ucl/...
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Quentin Huys @docqhuys.bsky.social · 14/09/2025
Proud husband! Ivana Gavric's new single is out m.youtube.com/watch?v=OegD...
m.youtube.com
Dora Pejačević Erinnerung (Remembrance) Op 24
YouTube video by Ivana Gavrić
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Joe Barnby @joebarnby.com · 03/09/2025
🧠 We're hiring a computational postdoc! 3+ years with me & @mitulamehta.bsky.social on @wellcometrust.bsky.social funded social cognition/paranoia research at the IoPPN. Lead & develop computational work, collaborate with experimentalists on psychosis/THC data. DM for details! lnkd.in/eCMy9Jf5
Computational postdoc ad for KCL funded by the Wellcome Trust on the NEPTUNE project
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Quentin Huys @docqhuys.bsky.social · 04/09/2025
The brain's priors have been found! They were hiding everywhere: www.nature.com/articles/s41.... So if this is true for "simple" decisions, it should also be true for more complex ones, like, say, emotions, right?
nature.com
Brain-wide representations of prior information in mouse decision-making - Nature
Brain-wide recordings in mice reveal that prior expectations are distributed through recurrent loops across all levels of cortical and subcortical processing.
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Elliott Wimmer @elliottwimmer.bsky.social · 20/08/2025
🧵 New paper! We studied depression symptoms and goal-directed decisions under uncertainty @shiyiliang.bsky.social, with @evanrussek.bsky.social & @robbrutledge.bsky.social Surprisingly, we found that apathy–anhedonia was linked to enhanced goal-directed behavior. www.biorxiv.org/content/10.1...
biorxiv.org
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Johannes Algermissen @johalgermissen.bsky.social · 20/08/2025
… Link here: www.biorxiv.org/cgi/content/... ... (2/15)
biorxiv.org
Low-intensity focused ultrasound to human amygdala reveals a causal role in ambiguous emotion processing and alters local and network-level activity
The amygdala is a core region changed in depression, a disorder characterized by compromised emotion, motivation and learning processes. However, lesion studies in humans examining amygdala function h...
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Tobias Hauser @tobiasuhauser.bsky.social · 19/08/2025
📢 We are hiring! 📢 For our @wellcometrust.bsky.social grant on information gathering biases in #OCD and #Schizophrenia, we are looking for a Postdoc in Computational Modelling, supervised by Peter Dayan and myself. Interested? See all the details in the job advert here: devcompsy.org/wp-content/u...
media.tenor.com
a penguin is sticking his head out of a hole next to a job application
ALT: a penguin is sticking his head out of a hole next to a job application
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Quentin Huys @docqhuys.bsky.social · 18/08/2025
Another exciting new job opening at @uclpals.bsky.social with Niko Steinbeis and Essi Viding - www.ucl.ac.uk/work-at-ucl/... #neurojob #computationalpsychiatry
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Quentin Huys @docqhuys.bsky.social · 18/08/2025
Still open!
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Department of Imaging Neuroscience @imagingneuroucl.bsky.social · 11/08/2025
🚨 We’re hiring: Associate Professor/Professor of Cognitive Neuroscience 🧠 Lead pioneering imaging-informed cognitive neuroscience research 🌍 Open to international applicants | Visa sponsorship available 📍 Permanent, full-time, on-site 🔗 Apply now: www.ucl.ac.uk/work-at-ucl/...
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Quentin Huys @docqhuys.bsky.social · 12/08/2025
#neurojob #psychiatry @rcpsych.bsky.social @uclqsion.bsky.social @relmed.bsky.social
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Quentin Huys @docqhuys.bsky.social · 12/08/2025
New position alert! This is an exciting position for a Specialty Doctor to take a leading role in developing the North London Mood Disorders Research Clinic in a national network of Mental Health Mission research clinics apps.trac.jobs/job-advert/7.... @noclor.bsky.social @uclpsychiatry.bsky.social
apps.trac.jobs
Specialty Doctor- Mood Disorders Research Clinic | Job advert | Trac
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Damien Fair @drdamienfair.bsky.social · 10/08/2025
I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...
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Quentin Huys @docqhuys.bsky.social · 10/08/2025
Associate Professor/Professor of Cognitive Neuroscience job opening in our own @imagingneuroucl.bsky.social department. Details here: www.ucl.ac.uk/work-at-ucl/...
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Quentin Huys @docqhuys.bsky.social · 16/07/2025
Here we go. #cpconf2025 is over. Thank you all for a superb conference and in particular @tobiasuhauser.bsky.social and Susan Fischer!
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relmed.bsky.social @relmed.bsky.social · 16/07/2025
Introducing our fantastic RELMED Team! 🧠 [Part 1] @docqhuys.bsky.social @nikkisingh.bsky.social
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Quentin Huys @docqhuys.bsky.social · 16/07/2025
The bar is high!
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Quentin Huys @docqhuys.bsky.social · 16/07/2025
@roelandheerema.bsky.social at #cpconf2025 talking about a new task linking specific emotional appraisals to computational states.
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Quentin Huys @docqhuys.bsky.social · 16/07/2025
Jiazhou Chen at #cpconf2025 on generalisation of MEG signatures of emotional states.
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relmed.bsky.social @relmed.bsky.social · 15/07/2025
The RELMED team @docqhuys.bsky.social @hylu.bsky.social @muzhiwang.bsky.social is presenting our study at #CPC2025 in Tübingen, Germany this week! Come find us at Poster Session 3 on Wednesday 16th July at poster number 3.24 and 3.26!
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Quentin Huys @docqhuys.bsky.social · 15/07/2025
Can we quantify mental states using LLMs? What are the limits? When does it and when does it not work and why? Jakub Onysk talking #cpconf2025
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Prof Joseph F Hayes @jfhayes.bsky.social · 09/07/2025
Since Davies & Read review of 2019 Sameer Jauhar and I have been trying to get closer to the truth about AD discontinuation. It’s entered guidelines as FACT: 50% will experience difficulty stopping. So we completed the DEFINITITIVE meta-analysis of trial data. jamanetwork.com/journals/jam...
jamanetwork.com
Incidence and Nature of Antidepressant Discontinuation Symptoms
This systematic review and meta-analysis examines the presence and incidence of discontinuation symptoms in individuals who stop taking antidepressants.
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Quentin Huys @docqhuys.bsky.social · 09/07/2025
V important meta-analysis doi.org/10.1001/jama...: Discontinuation symptoms 1 week post stopping antidepressants was below the threshold for clinically significant discontinuation syndrome. Later worse mood is likely depression relapse @jfhayes.bsky.social @sameerjauhar.bsky.social.
doi.org
Incidence and Nature of Antidepressant Discontinuation Symptoms
This systematic review and meta-analysis examines the presence and incidence of discontinuation symptoms in individuals who stop taking antidepressants.
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relmed.bsky.social @relmed.bsky.social · 03/07/2025
Come visit us at stall 48 to learn more about RELMED and get a personally drawn postcard from our friendly lab robotic arm 🤖🦾
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Quentin Huys @docqhuys.bsky.social · 02/07/2025
Deadline today - looking forward to the applications!
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Quentin Huys @docqhuys.bsky.social · 30/06/2025
@yanivabir.bsky.social and Zeguo Qiu are presenting exciting new behav & eeg battery of reinforcement learning tasks developed to see if different rl processes are selectively engaged by DA and 5HT. #BAP2025 @bapsych.bsky.social
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Quentin Huys @docqhuys.bsky.social · 30/06/2025
"substantially" is notable given this is in people with treatment-resistant depression, i.e. when there is a depression that has not responded to at least two other antidepressants.
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Quentin Huys @docqhuys.bsky.social · 30/06/2025
@mikebrowning.bsky.social‬'s paper on pramipexole in treatment-resistant depression is now out - very encouraging results authors.elsevier.com/sd/article/S....
eur01.safelinks.protection.outlook.com
ScienceDirect.com | Science, health and medical journals, full text articles and books.
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Federation of European Neuroscience Societies - FENS @fens.org · 17/06/2025
Early registration is OPEN for the next #BrainConference! 🧠 🇬🇷 For the first time ever, the Brain Conference is heading to Fodele Beach in Crete, Greece, and you’re invited! 🌟 Register by 10 July 2025 👉 loom.ly/ei_yabg @lundbeckfonden.bsky.social @brainprize.org
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Quentin Huys @docqhuys.bsky.social · 24/06/2025
Thank you @santhouse.bsky.social for this exploration of the blurry line between healthy and ill, of how cultural norms affect our views of who is ill. It highlights challenges when we get this wrong - like raising awareness without having sufficient answers. A very curageous and necessary book!
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Quentin Huys @docqhuys.bsky.social · 24/06/2025
Delighted to announce this position www.northlondonmentalhealth.nhs.uk/current-vaca.... It's part of the Mental Health Mission Mood Disorders Research Clinic Network, aiming to support clinical trials in mood disorders in the UK. Should be very interesting! oxfordhealthbrc.nihr.ac.uk/mhm/mood-dis...
northlondonmentalhealth.nhs.uk
Current vacancies
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Quentin Huys @docqhuys.bsky.social · 24/06/2025
Super to see this out! Pavlovian biases have shown predictive power a surprising range of settings, e.g. long-term course of alcohol use. Here, we find that Pavlovian biases are engaged by therapy; and that this engagement medicates outcomes in NHS setting. Congratulations @liobanause.bsky.social!
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MEGUKI 2025 @meguki2025.bsky.social · 17/06/2025
NEW DEADLINE: Friday 20th June 🚨 MEG‑UKI 2025 lands in London (16–18 July)! A 3-day deep dive into the brain—naturalistic neuroscience, OP-MEG, cutting-edge methods, and real-world impact. Keynotes by Dominik Bach & Jamie Ward. Art, abstracts, and more! Register here: meguk.ac.uk/registration/
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Quentin Huys @docqhuys.bsky.social · 17/06/2025
This was hard work, but ultimately there is support in the literature that engagement of different RL processes by serotonergic and dopaminergic/noradrenergic pharmacological interventions may be a promising route to follow. The @relmed.bsky.social study will do just that.
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Quentin Huys @docqhuys.bsky.social · 13/06/2025
Same for peer review methinks - let's not throw the baby out with the bathwater. www.science.org/content/arti...
science.org
Science’s reform movement should have seen Trump’s call for ‘gold standard science’ coming, critics say
Efforts to improve the rigor of research may have unwittingly handed the administration a way to attack science
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UCL Neuroscience Domain @ucl-neurodomain.bsky.social · 13/06/2025
We are delighted to announce that the 2025 UCL Neuroscience Symposium is now sold out! The symposium is UCL's flagship cross-faculty neuroscience event with hundreds of neuroscientists expected to attend. We look forward to seeing all those who registered next Wednesday!
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Quentin Huys @docqhuys.bsky.social · 02/06/2025
RELMED.ac.uk is now open to recruitment. This @wellcometrust.bsky.social-funded study wellcome.org/research-fun... will ask whether reinforcement learning tasks are differentially sensitive to dopaminergic and serotonergic antidepressants.
wellcome.org
Reinforcement Learning Mechanisms of Pharmacological Treatments for Depression (RELMED) - Grants Awarded | Wellcome
Reinforcement Learning Mechanisms of Pharmacological Treatments for Depression (RELMED)
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Quentin Huys @docqhuys.bsky.social · 26/05/2025
Thank you @clairelavalley.bsky.social and @rssmith.bsky.social. Striking to see aversive pruning altered in people with methamphetamine use, particularly given the results in depression (dx.doi.org/10.1017/S003...).
dx.doi.org
A comparison of ‘pruning’ during multi-step planning in depressed and healthy individuals | Psychological Medicine | Cambridge Core
A comparison of ‘pruning’ during multi-step planning in depressed and healthy individuals - Volume 52 Issue 16
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