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Duncan Smith

@laggingstrand.bsky.social
411 followers 578 following 33 posts

NYU biologist studying DNA replication. Passionate about undergraduate education. 🇺🇸🇬🇧. Views my own, and all that

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Reposted by Duncan Smith
Axel Delamarre @axeldelamarre.bsky.social · 18/12/2025
Hello everybody, I am looking for an Engineer (IE) to help me start the lab at LBMC / ENS-Lyon in April. We will investigate chromatin organization during replication in yeast. RT appreciated! To apply: inserm.softy.pro/offre/187863 @lbmcinlyon.bsky.social #NewPI #3DGenome #chromatin #replication
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Tom Ewing @tomewing.bsky.social · 13/09/2025
If I were the UK Government I would simply not route all my communications through the platform whose owner just called for regime change in Britain and said "fight back or die"
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Jason Kirk @jasonkirk.fyi · 12/09/2025
Discovering computer as an adult makes you go crazy. Discovering computer as a baby makes you go crazy. In all of human history, there will only ever be one generation to discover computer at the correct age: 13
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Nick Bednar @nicholasbednar.bsky.social · 06/09/2025
One of the greatest errors in K-12 education, in my opinion, is prioritizing trigonometry and calculus over statistics. Yes, trig and calc are important for many professions. Statistics are important for literacy.
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Samuel Church @shchurch.bsky.social · 28/08/2025
The Church Evolution Laboratory (CEL@NYU) will be official as of Sep 1st: shchurch.github.io. We are recruiting at all levels, including a postdoc to work on evolutionary patterns and processes via comparative genomics in Hawaiian Drosophila. Please share widely!
shchurch.github.io
Church Evolution Laboratory
Department of Biology, New York City
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JStark lab @jstarklab.bsky.social · 27/07/2025
4% payline demoralizing for reviewers - review 9 grants each taking 3-4hrs (total reviewed by all is 90) flying to DC, a hotel conference room to discuss the top half of grants (45) 15 min each, 3x a year for 4 yrs. Paid $300. 4% = maybe 3/90, 0-1 that you reviewed funded. I couldn’t.
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Duncan Smith @laggingstrand.bsky.social · 23/05/2025
When I taught intro biology I spent a lot of time training bad AP habits out of the students. We let them bring in AP and skip that sequence but they are far less prepared for downstream courses if they do
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Chloë R McKenzie @chloermckenzie.bsky.social · 21/05/2025
Success in academia often has more to do with luck, patronage and the job market than “hard work”. Good academics acknowledge this. I worked hard, but I was in the right place at the right time on occasion. Historians far more talented than I have fallen between the cracks.
Illustration showing a graduation ceremony, with speaker addressing graduates: “Let the example of my fluke success guide nearly all of you to crushing disappointment”.
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Cathy Gao-Howard MD MS @catgaohow.bsky.social · 18/05/2025
Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025
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Michael Baym @baym.lol · 14/05/2025
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
A screenshot of the termination notice showing "Outstanding Investigator Grants"A screenshot of the termination notice with "This award is terminated effective the date of this award, due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." highlighted
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Duncan Smith @laggingstrand.bsky.social · 01/05/2025
Great opportunity to join a new lab doing exciting science. Neurons! Mitochondria! RNA transport!
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Chris Hayes @chrislhayes.bsky.social · 25/03/2025
I'm not saying anything novel here but it really is just truly despicable to watch them use THEIR OWN COLOSSAL SCREW UP to slander the reporter THEY INCLUDED ON THEIR CLASSIFIED GROUP CHAT
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Rebecca Fielding-Miller @rebeccafieldingmiller.com · 22/03/2025
Today I lost an NIH grant training clinicians to do research about intimate partner violence with perinatal women. More women are murdered in the perinatal period than die of obstetric complications. I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
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Duncan Smith @laggingstrand.bsky.social · 23/03/2025
www.theguardian.com/commentisfre...
theguardian.com
Columbia should have said, ‘see you in court,’ not ‘yes, Mr President.’ | Margaret Sullivan
Institutions must resist thuggish bullying. There is no satisfying Trump. He will move the goalposts again and again
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Isi Baehr-Breen @isibb.bsky.social · 22/03/2025
So we’ve got two competing schools of what the Democratic Party should do next. One of them is hosting the largest political rallies in history in places like New Hampshire and Arizona, and the other one just got $120 million from Silicon Valley and is on a book tour.
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Aaron Rupar @atrupar.com · 20/03/2025
This is like Gina Raimondo going on MSNBC and telling people to buy Hunter Biden’s paintings, only if Hunter was the unelected co-president and not a private citizen
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Amy Spitalnick @amyspitalnick.bsky.social · 19/03/2025
The Trump admin cut $400 million from Columbia under the guise of “protecting Jews.” Now they’re freezing $175 million in Penn funds under the guise of “protecting women.” It’s not about protecting any of us. It’s about gutting our institutions and our democracy. www.thedp.com/article/2025...
thedp.com
Trump administration freezes $175 million in federal funding to Penn
According to a White House tweet, Wednesday's decision is a result of Penn's
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George Conway ⚖️🇺🇸 @gtconway.bsky.social · 19/03/2025
Schumer needs to quit. He’s useless. Completely clueless.
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Duncan Smith @laggingstrand.bsky.social · 19/03/2025
"Knowing fully that this moment transcends my individual circumstances, I hope nonetheless to be free to witness the birth of my first-born child"
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Popehat @kenwhite.bsky.social · 19/03/2025
Fentanyl is very much like a weapon of mass destruction in the sense that Republicans like to lie about finding it and then use that lie as a justification to do ruinous, destructive things
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Kelton Minor @keltonminor.bsky.social · 18/03/2025
There are days in life that shake you. I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University & academic career... 1/🧵
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Clare Abreu @clabreu.bsky.social · 18/03/2025
My lab at NYU is hiring a postdoc in microbial ecology and evolution! We are looking for someone interested in both wet and dry lab techniques, including experimental evolution, genome editing, bioinformatics, and some modeling. Apply here: apply.interfolio.com/164683
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Duncan Smith @laggingstrand.bsky.social · 18/03/2025
Zero new awards from NIGMS from 2/4 to today reporter.nih.gov/search/tsnSE...
reporter.nih.gov
RePORT ⟩ RePORTER
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Hakeem Jefferson @hakeemjefferson.bsky.social · 15/03/2025
One reason this government can so easily frame protesters as terrorists is that others—including some at universities—have already laid the groundwork. When we treat students engaged in constitutionally protected speech like criminals, we make it easier for authoritarian governments to do the same.
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Jameel Jaffer @jameeljaffer.bsky.social · 14/03/2025
I’m told this is a real letter. It basically says, “We’ll destroy Columbia unless you destroy it first.”
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Alexandria Ocasio-Cortez @aoc.bsky.social · 14/03/2025
New Yorkers: Call Sen. Gillibrand’s office to vote NO on cloture and NO on the Republican Spending Bill. They vote in the morning. ☎️: (202) 224-4451
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Aaron Rupar @atrupar.com · 13/03/2025
if Trump and his cronies are able to veto appropriations made by Congress, then we've already moved into a dictatorial system of government. Why would Democrats waste time negotiating spending deals if Trump can just rip them up after he signs them?
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Aaron Rupar @atrupar.com · 12/03/2025
Tommy Tuberville: "When it comes to protesters, we gotta make sure we treat all of them the same: send them to jail."
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alexandra @aliemalie.bsky.social · 12/03/2025
Great job, Sen. Dr. Bill Cassidy. This is what you, a physician, voted to confirm to lead Health and Human Services. Pa-fucking-thetic.
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Chris Hayes @chrislhayes.bsky.social · 11/03/2025
I know this is going to sound naive or earnest, but I genuinely find myself shocked by how little people seem to be upset by the levels of corruption we're seeing. Is that the median voter assumes everyone is corrupt already? Or isn't actually getting stories about the corruption?
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National Security Counselors 🕵 @nationalsecuritylaw.org · 11/03/2025
@propublica.org reporter Brett Murphy with an explosive scoop. This is insanity.
ProPublica just obtained a remarkable directive to those remaining at USAID: Empty the safes with the classified and personnel records and then ...

"Shred as many documents first, and reserve the burn bags for when the shredder becomes unavailable or needs a break."

The email came from from the agency's acting executive secretary. I asked Kel McClanahan, a national security attorney, if this was legal. He said: "No it is not," citing the Federal Records Act. "Classified records are still federal records."
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Coleen Murphy @ctmurphy1.bsky.social · 11/03/2025
A dear friend of mine just had all her funding pulled. All she has ever done is work exceptionally hard to do excellent science and help others do great science. This is heartbreaking
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Matt Rockman @wormsrock.bsky.social · 10/03/2025
Not just students— hundreds of faculty are on visas or green cards
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TW @twesq.bsky.social · 09/03/2025
I’m not sure I’ve ever seen a more apt metaphor
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Jacqueline Sweet @jsweetli.bsky.social · 07/03/2025
SCOOP: The new DOGE official seeking private taxpayer information at the IRS has ties to a sanctioned Russian oligarch considered part of Putin's inner circle. Sam Corcos is married to a woman who partnered w/ a VC firm handling Suleyman Kerimov's money. www.rollingstone.com/politics/pol...
rollingstone.com
New DOGE Staffer Has Ties to a Sanctioned Russian Oligarch
Corcos, a new member of Elon Musk’s DOGE team, reportedly showed up at the IRS demanding detailed info about American taxpayers to hunt for fraud.
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Dirk Remus @dirkremus.bsky.social · 06/03/2025
How do replisomes walk on DNA? And what happens when they run into a G-quadruplex? @sahilbatra.bsky.social and @benallwein.bsky.social provide unexpected insight in our latest paper with Richard Hite @mskcancercenter.bsky.social @science.org www.science.org/doi/10.1126/.... Congrats to all authors!
science.org
G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation
DNA G-quadruplexes (G4s) are non–B-form DNA secondary structures that threaten genome stability by impeding DNA replication. To elucidate how G4s induce replication fork arrest, we characterized fork ...
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Nature @nature.com · 06/03/2025
In an unprecedented move, the US National Institutes of Health has begun mass terminations of research grants that fund active scientific projects because they no longer meet “agency priorities”. go.nature.com/4bpG2It
go.nature.com
Exclusive: NIH to terminate hundreds of active research grants
Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.
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John Br👻OoOOOoOoo👻ks @johnbrooks.bsky.social · 04/03/2025
Rebuilding after Trump is gonna be like rebuilding after someone destroys the Lego town you've been building for 250 years and everyone who knows how to help you build it is gone and you're missing half the bricks and they don't make the instruction manuals anymore and also you're dead
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S.J. Pearce @homophonous.bsky.social · 04/03/2025
#LRP I recognize we’re talking about hundreds of millions of dollars in federal research funding for med schools but at some point universities need to draw a hard line & refuse to comply. First because it’s right & second because it’s not like the research funding isn’t going to get cut anyway.
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Hari Kunzru @harikunzru.bsky.social · 04/03/2025
I need the institution where I teach (NYU) to respond clearly and unequivocally saying this is unconstitutional and they will not be adhering to it. This is a red line.
Trump tweets: All Federal Funding will STOP for any College, School, or University that allows illegal protests. Agitators will be imprisoned/or permanently sent back to the country from which they came. American students will be permanently expelled or, depending on on the crime, arrested. NO MASKS! Thank you for your attention to this matter.
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Duncan Smith @laggingstrand.bsky.social · 04/03/2025
PIs, dammit autocorrect
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Duncan Smith @laggingstrand.bsky.social · 04/03/2025
Oof, sorry. 10-20% of all GM paid in similar boats, presumably. I guess we try to stay optimistic for as long as possible? Those who interact with me regularly may recognize this as a case of ‘do as I say, not as I do’ but since I have young kids I’m totally allowed to play that card
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Wyoming Wormboy @wyomingwormboy.bsky.social · 03/03/2025
Any word on when NIGMS council might meet? Like many others I have a grant that’s been stalled and I have good people depending on these funds. I’ve heard nothing.
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Duncan Smith @laggingstrand.bsky.social · 04/03/2025
This, but wistfully staring at a dumpster fire instead of the ocean
media.tenor.com
a man looking out over the ocean from a pier
Alt: a man looking out over the ocean from a pier,
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Duncan Smith @laggingstrand.bsky.social · 04/03/2025
MIRA is (hopefully we can still use the present tense) a fantastic model under normal circumstances. I'm a big fan of the long-term lab evolution model. Selfishly, it really allowed us to change directions after a full lab turnover immediately post-covid. They're also a joy to review Vs R01s
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Duncan Smith @laggingstrand.bsky.social · 04/03/2025
Yep - I'm one of these. Flurry of emails on 1/22 and 1/23 from the Grants Management Specialist about effort/JIT tweaks, then radio silence. Original grant ended 2/28 so running on residual startup now
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Jeremy Berg @jeremymberg.bsky.social · 02/03/2025
I am not going to call this a Bluetorial, because I do not want to sully that term (which, at least I, find joyful). Let’s call it a Orwellial.
media.tenor.com
a cartoon of homer simpson holding a card
ALT: a cartoon of homer simpson holding a card
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Duncan Smith @laggingstrand.bsky.social · 01/03/2025
Will DM you the response in case they don’t want it to be public: suffice to say it’s uncertain and not optimistic
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Duncan Smith @laggingstrand.bsky.social · 01/03/2025
I have of late - and wherefore is blindingly fucking obvious - lost all my mirth
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