Daniel welcomes his niece, who is affected by a rare neurological disorder, and Dr. Roy Sillitoe, a researcher who studies her condition. Support Dr. Roy’s research http://giv.now/csc Support individuals and families affected by Hadley’s condition https://www.pou4f1foundation.org/donate Join our Patreon for exclusive content: http://patreon.com/toshshow Get started today at http://StitchFix.com/tosh to get $20 off your first order—and they’ll waive your styling fee. Text DAN to 64000 to get a FREE pocket pivot and their 10-pattern sprayer with the purchase of ANY size Copper Head hose. Message and data rates may apply Get 25% off your subscription or try the app FREE for seven days at http://Fitbod.me/TOSH http://quince.com/tosh for free shipping on your order and 365-day returns SUBSCRIBE to watch more tosh show https://www.youtube.com/@toshshow TOUR DATES https://www.danieltosh.com/#tour FOLLOW DANIEL TikTok https://www.tiktok.com/@danieltosh Instagram https://www.instagram.com/danieltosh Twitter https://twitter.com/danieltosh ABOUT TOSH SHOW Tosh Show is a window into the mind of comedian Daniel Tosh. Each week, Daniel interviews people from all walks of life that he finds interesting, shares his take on current events, and gives you a little insight into his world. Nothing is off limits, and with endless topics to explore, Tosh and his guests will satisfy everyone's curiosity. Co-Creator/Executive Producer: John Elerick Co-Creator/Executive Producer: Eddie Gossling Co-Creator/Executive Producer: Peter Relyea Audio Engineer: Dylan Stern tosh show https://www.youtube.com/@toshshow Get in touch: toshshow@danieltosh.com

Decreased brain coenzyme Q10 levels cause encephalopathy and are associated with neurodegeneration; supplementation with 4-HMA or 4-HB restores coenzyme Q10 synthesis in mice and humans with HPDL vari...

Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...

New research identifies age-related damage on a cellular level

YouTube video by Allen Institute

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The FDA’s nod for suzetrigine bolsters confidence in the pharmaceutical industry’s strategy to target sodium channels.

Tiny specks called biomolecular condensates are leading to a new understanding of the cell

The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.

Age-related neurodegenerative diseases involve reduced cell numbers and impaired behavioral capacity. Neurodegeneration and behavioral deficits also occur during aging, and notably in the absence of d...

Oby, Degenhart, Grigsby and colleagues used a brain–computer interface to challenge monkeys to override their natural time courses of neural activity. They found the time courses to be highly robust, ...

In a discovery that challenges our understanding of social behavior, researchers have found that tiny single-celled organisms can coordinate their actions

When Jeff Yau started having strange symptoms after his COVID-19 infection – numbness, tingling, and shaking – he experienced what thousands of others with long COVID have found: answers were hard to ...

Zheng and Meister write about the paradoxical slowness of human behavior. Although our senses gather data at 109 bits/s, our overall information throughput is only 10 bits/s. This stark contrast touches on many fundamental aspects of brain function.

Neurocognitive congruence is key to designing artificial touch that best integrates with human perception and action.

Brains balance individual neuron activity and scalable teamwork using a fractal hierarchy, optimizing efficiency and adaptability. This universal principle, found across species, enables resilience and rapid adaptation.

How the brain routinely processes information from different sensory modalities during everyday tasks is not well understood. In this Perspective, Engel and Senkowski propose how oscillatory neural me...

The Allen Institute for Brain Science's MapMySpikes challenge aimed to address a key challenge in neuroscience by making connections between cells' electrical and molecular properties.

Age, the chief risk factor for numerous neurodegenerative disorders, impairs AAV CNS transduction. Sandoval and colleagues tested AAV2 capsid mutants in their ability to overcome this impairment in aged rats. Mutants exhibited improved transduction, albeit still reduced with age. Interestingly, one variant exhibited improved intracellular transport to projection areas.

Early-life stress can have lifelong consequences, enhancing stress susceptibility and resulting in behavioural and cognitive deficits. While the effects of early-life stress on neuronal function have ...

A computational model shows that preparation arises as an optimal control strategy in input-driven recurrent neural networks performing a delayed-reaching task.

The 2025 Gordon Research Seminar on Cerebellum (GRS) will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.

The 2025 Gordon Research Seminar on Cerebellum (GRS) will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.

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The role of the motor cortex in executing motor sequences is widely debated, with studies supporting disparate views. Here we probe the degree to which the motor cortex’s engagement depends on task...