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Katherine McVay, PhD

@katherinemcvay.bsky.social
1.7K followers 1.3K following 12 posts

Postdoctoral Associate at Duke with @amygoldberg.bsky.social | ev gen, conservation, and pathogens 🧬🐒🦠 katherinemcvay.weebly.com

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Reposted by Katherine McVay, PhD
Science Magazine @science.org · 05/10/2026
Exclusive: A new analysis refutes James Watson’s claim that he was the first to recognize the significance of the famed photograph 51. scim.ag/4rTKck8
scim.ag
How did Rosalind Franklin miss the helix in her iconic DNA image? She didn’t
New analysis refutes James Watson’s claim he was first to recognize significance of famed photograph 51
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Katherine McVay, PhD @katherinemcvay.bsky.social · 16/10/2025
Pat and Pedro are wonderful collaborators and colleagues! Definitely give this book a read if you’re interested in conservation genetics in the context of the rich diversity of the Neotropics.
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Reposted by Katherine McVay, PhD
Maria Akopyan, PhD @akopyan.bsky.social · 22/09/2025
Now published in Cell! We found that ~15% of SNPs from divergent refs did not liftover as SNPs in the gray fox ref—half mapped to monomorphic sites, half failed to map. Co-authored with Matthew Genchev, @elliecat.bsky.social, and @jazlynmooney.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Reference genome choice compromises population genetic analyses
Characterizing genetic variation in natural populations is vital to evolutionary biology; however, many non-model species lack genomic resources. Here…
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Reposted by Katherine McVay, PhD
Colin Carlson @colincarlson.bsky.social · 22/09/2025
🦇🦠 New preprint - in a long-term effort led by the amazing @mayajuman.bsky.social, we've shown that the ML tools developed by @viralemergence.org let us efficiently screen museum collections for pathogens with pandemic potential 🎉🔓 www.biorxiv.org/content/10.1...
biorxiv.org
Museum collections and machine learning guide discovery of novel coronaviruses and paramyxoviruses
Natural history museum collections are valuable but underutilized resources for viral discovery, offering opportunities to test hypotheses about viral occurrence across space, time, and taxonomic grou...
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Reposted by Katherine McVay, PhD
marilou boddé @mariloumercedes.bsky.social · 18/09/2025
Our paper Genomic diversity of the African malaria vector Anopheles funestus was published in Science today! It features inversions, selection in action, museum specimens and putative new ecotypes. doi.org/10.1126/scie...
doi.org
Genomic diversity of the African malaria vector Anopheles funestus
Anopheles funestus s.s. is a major human malaria vector across Africa. To study its evolution, especially under vector control pressure, we sequenced 656 modern specimens (collected 2014 to 2018) and ...
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Katherine McVay, PhD @katherinemcvay.bsky.social · 19/09/2025
My first Perspective piece was just published in Science! I discuss the new findings by @amandalea.bsky.social and colleagues showing adaptations to water stress in the Turkana, and the implications of past adaptations for future disease risk.
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Katherine McVay, PhD @katherinemcvay.bsky.social · 18/08/2025
I’m excited to be attending #ESEB2025 this week in Barcelona! If you’re interested in chatting about primate population genetics, come chat with me at my poster this evening - P01.275 Genomics of Brazilian howler monkeys reveals recent inbreeding and species-specific positive selection
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Reposted by Katherine McVay, PhD
Graham Coop @gcbias.bsky.social · 08/04/2025
Inside me there are two wolves. One of them has a 15 genome edits the other 20 genome edits. Neither of them is a dire wolf.
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Reposted by Katherine McVay, PhD
Colin Carlson @colincarlson.bsky.social · 15/01/2025
🚨😷🧪 NEW: A growing body of evidence shows that pandemics, biodiversity loss, and climate change are part of a broader polycrisis - but there are no simple solutions. A sweeping overview of "Pathogens and planetary change" for the first issue of @natrevbiodiv.bsky.social, out now 🔓 rdcu.be/d6lHl
Top panels: graphs showing increases in spillover events, extinction rates, and temperature anomalies over the last few centuries. Bottom panel: a map of 10 pandemics since the year 1900. Four were linked to agriculture, two to wildlife use, and one to climate change.
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Reposted by Katherine McVay, PhD
The Prehistoric Society @prehistoricsociety.bsky.social · 15/01/2025
*BREAKING* "The results revealed that this community was centred around bonds of female-line descent.” #Archaeology #Prehistory #IronAge www.nature.com/articles/s41...
nature.com
Continental influx and pervasive matrilocality in Iron Age Britain - Nature
An analysis of ancient mitochondrial and nuclear DNA shows evidence of matrilocal communities in Iron Age Britain.
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Katherine McVay, PhD @katherinemcvay.bsky.social · 12/01/2025
Absolutely loved hearing about this work at SMBE24 this past summer and subsequently leading a lab meeting discussion on the preprint. Fantastic to see it published!
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Reposted by Katherine McVay, PhD
marilou boddé @mariloumercedes.bsky.social · 18/12/2024
Preprint is out! We investigated the genomic diversity and evolutionary history of Anopheles funestus mosquitoes, one of the main species transmitting human malaria across Africa. Here’s a visual summary. Art by @petrathepostdoc.bsky.social . 1/8 www.biorxiv.org/content/10.1...
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Katherine McVay, PhD @katherinemcvay.bsky.social · 19/12/2024
Congrats to my fellow Duke EvAnth grad student Alisha Anaya 🎉 She put in so much effort scanning and recording this material, it’s great to see it come together!!
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Katherine McVay, PhD @katherinemcvay.bsky.social · 18/12/2024
Being able to accurately identify physical interactions between host and receptor proteins is critical for research on host shifts/zoonoses as these interactions often mediate susceptibility. This type of research is important for future pandemics and research on treatment and vaccine development.
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Reposted by Katherine McVay, PhD
Hernán E. Morales @hernmoral.bsky.social · 18/12/2024
With the Crane Foundation & amazing co-authors, we analyzed 150+ years of genomic data, revealing whooping cranes have lost 70% of their genetic diversity and accumulated harmful mutations. Despite conservation successes, they remain vulnerable. We argue keeping their endangered status
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Katherine McVay, PhD @katherinemcvay.bsky.social · 18/12/2024
Fantastic to see this research come together! These questions can be addressed with significantly higher certainty using pathogen paleogenomics as shown here.
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Reposted by Katherine McVay, PhD
Health Nerd @gidmk.bsky.social · 17/12/2024
Nearly five years after publication, and after 4,000 retractions, the paper that sparked the use of hydroxychloroquine for COVID-19 has been retracted. The publisher cites a range of scientific and ethical concerns. I have some thoughts 1/n
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Reposted by Katherine McVay, PhD
Alida de Flamingh @adeflamingh.bsky.social · 18/12/2024
Using hair found in the teeth of the infamous lions named the "Tsavo Man-Eater's," scientists uncover their diet consisted of humans, giraffes, and more. @currentbiology.bsky.social www.cell.com/current-biol...
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Reposted by Katherine McVay, PhD
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 10/12/2024
Beautiful paper from the Elizabeth Winzeler laboratory at UC San Diego out today in Science building a predictive model of malaria drug resistance by analyzing the genomes of 724 parasite genomes evolved in the lab to resist one of 118 different antimalarial compounds today.ucsd.edu/story/a-new-...
today.ucsd.edu
A New Approach to Predicting Malaria Drug Resistance
Researchers at UC San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance.
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Katherine McVay, PhD @katherinemcvay.bsky.social · 06/12/2024
Host specificity can be a super complex phenotype so to see such a clear example of a single mutation driving the shift is both fascinating and worrying!
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Reposted by Katherine McVay, PhD
SK Winnicki, PhD 🏳️‍⚧️ @skwinnicki.bsky.social · 04/12/2024
My sister’s got an epic new paper out! She’s a PhD candidate working on infectious diseases, including this work on malaria therapeutics: www.nature.com/articles/s41...
nature.com
Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages - Nature Communications
Here the authors isolate monoclonal antibodies specific for Plasmodium vivax apical membrane antigen 1, and characterize the epitope of one antibody that inhibits invasion of reticulocytes and hepatoc...
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Reposted by Katherine McVay, PhD
Maggie Steiner @maggiesteiner.bsky.social · 04/12/2024
Excited to share a new preprint with @jnovembre.bsky.social ! We use a combination of population genetic theory, simulation, and data analysis to ask: how does study design in genetic studies (including biobanks) impact the discovery of rare, deleterious variants?
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Reposted by Katherine McVay, PhD
Meghie Rodrigues @meghier.bsky.social · 26/11/2024
Thank you so much to whoever put this very comprehensive list of #science Bsky starter packs together. This is just amazing: docs.google.com/document/d/1...
docs.google.com
Starter packs
BIOLOGY General Science community https://go.bsky.app/HVYAMEA Research Institutions in Life Sciences https://go.bsky.app/LxXpcvJ LGBTQIA+ in STEM https://go.bsky.app/BFc4wgf LGBTQIA+ in STEM 2 h...
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Katherine McVay, PhD @katherinemcvay.bsky.social · 03/12/2024
Love to see genomics and linguistics analyzed together! Cool paper importantly demonstrating how ancient DNA can answer questions in other disciplines. #aDNA
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Reposted by Katherine McVay, PhD
Gen Wojcik @genandgenes.bsky.social · 02/12/2024
Work by PhD student @jayatirsharma.bsky.social on how grouping Hispanic/Latino participants into a single group can obfuscate substantial substructure, leading to false conclusions. We show how heterogeneity by background group wrt genetic ancestry and environment can affect genetic risk models.
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Reposted by Katherine McVay, PhD
bioRxiv Genomics @biorxiv-genomic.bsky.social · 02/12/2024
A forest is more than its trees: haplotypes and inferred ARGs www.biorxiv.org/content/10.1101/202…
biorxiv.org
A forest is more than its trees: haplotypes and inferred ARGs https://www.biorxiv.org/content/10.1101/2024.11.30.626138v1
Foreshadowing haplotype-based methods of the genomics era, it is an old observation that the ``junct
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Reposted by Katherine McVay, PhD
Laurits Skov @lauritsskov.bsky.social · 02/12/2024
Very excited (and a bit nervous) to announce that I will be hiring two Postdocs for my new group(!) in Copenhagen to study the Neanderthal and Denisovan DNA which survives in present-day humans. Retweet will be much appreciated :) Link for application: candidate.hr-manager.net/ApplicationI...
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Reposted by Katherine McVay, PhD
David Fisman. @dfisman.bsky.social · 29/11/2024
Sure! Probably the first thing to know is that there is a whole range of particle sizes that we produce when we use our lungs, voice boxes, mouths and noses (our respiratory tract). Some of those are “big” and heavy: maybe you get splattered by a person talking to you.
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Katherine McVay, PhD @katherinemcvay.bsky.social · 02/12/2024
Great opportunity and sounds like a fascinating project, can’t wait to read the results!
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Reposted by Katherine McVay, PhD
Jazlyn Mooney @jazlynmooney.bsky.social · 01/12/2024
First major paper from the lab! The work was led by super talented postdoc Maria Akopyan. She explored how reference bias skews estimates of diversity, demography, divergence & recombination rate with help from @elliecat.bsky.social & awesome ungrad Matthew. Full thread coming soon 🤓
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Reposted by Katherine McVay, PhD
Paulina Arancibia @pauliarancibia.bsky.social · 30/11/2024
I created this stater pack with women in ecology and evolution. If you want to be added you can comment or DM me, but also please suggest the names of those I am missing 🧪🌎🌐 go.bsky.app/8jFH7cS
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