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Karine G Le Roch

@karineleroch.bsky.social
128 followers 141 following 7 posts

Professor and Parasitologist captivated by the biology of apicomplexan parasites in general and malaria parasites in particular! Yoga addict and New in 🦋

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Reposted by Karine G Le Roch
Ira Blader @bladerlab.bsky.social · 01/07/2025
Today, I assume my new role as Editor-in-Chief of #mSphere published by @asm.org. In this editorial , I discuss where the journal is today and where it is going. mSphere’s journey and future: a message from the new editor in chief | mSphere journals.asm.org/doi/10.1128/...
journals.asm.org
mSphere’s journey and future: a message from the new editor in chief | mSphere
Readers know that mSphere was launched in 2015 as a pan-microbial, multidisciplinary open-access journal that publishes high-quality, high-impact work across the microbial sciences. However, some may ...
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Reposted by Karine G Le Roch
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 01/07/2025
This is a catastrophe in the making gizmodo.com/rfk-jr-says-...
gizmodo.com
RFK Jr. Says AI Will Approve New Drugs at FDA 'Very, Very Quickly'
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Karine G Le Roch @karineleroch.bsky.social · 01/07/2025
news.ucr.edu/articles/202...
news.ucr.edu
Pair of malaria parasite proteins could lead to therapies
A University of California, Riverside-led team has made an advance in the basic understanding of Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, that could mak...
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Reposted by Karine G Le Roch
Shannon Scott-Vernaglia, MD @scottvernaglia.bsky.social · 16/04/2025
"Thirty-eight of 43 experts cut last month from the boards that review the science and research that happens in laboratories at the National Institutes of Health are female, Black or Hispanic, according to an analysis by the chairs of a dozen of the boards."
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Karine G Le Roch @karineleroch.bsky.social · 15/04/2025
This is so sad! www.who.int/news/item/11...
who.int
Malaria progress in jeopardy amid foreign aid cuts
The 2025 funding cuts to malaria programmes put millions of additional lives at risk and could reverse decades of progress earned
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Reposted by Karine G Le Roch
WIRED @wired.com · 01/04/2025
NEW: Thousands of CDC employees who worked on things like preventing HIV and lead poisoning have been told they were subject to a reduction in force. Experts say people will die.
wired.com
The CDC Has Been Gutted
Thousands of CDC employees who worked on things like preventing HIV and lead poisoning have been told they were subject to a reduction in force. Experts say people will die.
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Science Magazine @science.org · 17/03/2025
For the first time, researchers have used the #CRISPR gene editor to repair a flawed gene in the human body. scim.ag/3RdMzMT
scim.ag
Gene editing fixes DNA—and treats incurable lung and liver disease
A promising clinical trial marks another milestone for the CRISPR gene editor
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Reposted by Karine G Le Roch
Richard Branson @richardbranson.bsky.social · 25/02/2025
For the US to side with Russia and North Korea to oppose a UN resolution condemning the illegal invasion of Ukraine defies all common sense and adds insult to the countless injuries suffered by the brave Ukrainian people. edition.cnn.com/2025/02/24/p...
edition.cnn.com
US joins Russia to vote against UN resolution condemning Russia’s war against Ukraine | CNN Politics
The United States joined Russia to vote against a UN General Assembly resolution condemning Russia’s war against Ukraine Monday in a stunning shift from years of US policy.
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Eric Topol @erictopol.bsky.social · 25/02/2025
Good summary on microplastics and our health risks nymag.com/intelligence...
nymag.com
Everything You Ever Wanted to Know About Microplastics
They’re in our blood and our brains. They’re in newborns and the elderly, urban and rural, rich and poor. What are they doing to our bodies?
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Reposted by Karine G Le Roch
Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 26/02/2025
Just got this passed on to us, about the damage at NIH's home campus -- the largest biomedical research institute in the world. "The articles on cuts and damage assessments are largely grants focused. The grants program is a bit easier to characterize because it’s visible outside the NIH..." 🧪 1/
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Anand Ray @anandray.bsky.social · 25/02/2025
PASS IT ON “The 24 hour Economic Blackout" - Posted by Jon Stewart WHEN: Friday February 28th from 12:00 A.M. to 11:59 P.M. Do not make any purchases Do not shop online, or in-store: No Amazon, No Walmart, No Best Buy…Nowhere! Do not spend money on Food & Gas; Do not use cards
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bioRxiv Genomics @biorxiv-genomic.bsky.social · 26/02/2025
Mosquito Cell Atlas: A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito www.biorxiv.org/content/10.1101/202…
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Reposted by Karine G Le Roch
Ardem Patapoutian @ardemp.bskyverified.social · 25/02/2025
OpEd by @scripps.edu Pres. Pete Shultz: "the consequences would extend beyond Scripps Research, threatening the broader San Diego life sciences ecosystem, which contributes over $27 billion to the regional economy and supports tens of thousands of jobs." www.sandiegouniontribune.com/2025/02/25/o...
sandiegouniontribune.com
Opinion: Science funding cuts are based on flawed logic. Here’s the truth.
Earlier this month, the National Institutes of Health issued supplemental guidance indicating it would immediately impose a 15% cap on indirect costs for research grants, an unprecedented and abrup…
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Karine G Le Roch @karineleroch.bsky.social · 19/02/2025
Our research community has been under attack. We know how important the research we do is – without it, jobs will be lost, clinical trials will be canceled, and life-saving discoveries will never be made.  Please spread the word and sign the letter docs.google.com/forms/d/1Agz...
docs.google.com
Protect NIH Research: Advocate for Full Funding
As researchers representing universities across the country, the last few weeks have been filled with uncertainty. As you are aware, the Trump administration’s National Institutes of Health (NIH) prop...
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Reposted by Karine G Le Roch
Jeremy Berg @jeremymberg.bsky.social · 16/02/2025
Thanks to all of the NIHers and their friends who reached out to me. I am still here (DM me or Signal jeremymberg.78) I still have a very incomplete picture but based on what I have been told, the damage to NIH and to many wonderful people who work(ed) there is/was impossible for me to imagine 1/n
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Richard Branson @richardbranson.bsky.social · 15/02/2025
Europe can’t rely on the strength of the transatlantic relationship to help contain Russia’s threat – it must lead from the front and be the true force of support that Ukraine needs. Not just for Ukraine’s sake, but for a free and sovereign Europe.
virgin.com
On Ukraine, Europe must step into the void | Virgin
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Jonathan Eisen @phylogenomics.bsky.social · 15/02/2025
Congrats to all elected as Fellows of the American Academy of Microbiology asm.org/Press-Releas...
asm.org
65 Fellows Elected Into the American Academy of Microbiology
The Academy elected 65 new fellows to the Class of 2025.
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Katie Sandlin @kmsandlin.bsky.social · 14/02/2025
Today, along with 2,000 other NIH employees, I had to clear out my office 😭 It was truly the honor of my life to work with such incredibly passionate people focused on improving human health. I’ve never experienced a more positive culture where *everyone* cared about their job and serving others.
Office desk without any personal items or decor
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Helen Branswell 🇨🇦 @helenbranswell.bsky.social · 14/02/2025
Doing the unthinkable: The deep cuts to the #CDC's workforce today are expected to decimate the Epidemic Intelligence Service, a program that has trained public health rapid responders for decades. Envy of the world. Poof! www.statnews.com/2025/02/14/t...
statnews.com
CDC cuts expected to devastate Epidemic Intelligence Service, a ‘crown jewel’ of public health
Members of the CDC's Epidemic Intelligence Service were warned Friday that many of them were about to be fired
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Reposted by Karine G Le Roch
Jeremy Berg @jeremymberg.bsky.social · 28/01/2025
Academic Skyers: I am compiling a list of policies and statements from various universities about how they are handling the "pause" in terms of stopping expenditures (or not). Please respond to this post with your institution and materials. THANK YOU!
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Reposted by Karine G Le Roch
Senator Patty Murray @murray.senate.gov · 08/02/2025
This is what amounts to an ILLEGAL & indiscriminate funding cut for research centers everywhere. It will mean shuttering labs across the country, layoffs in red & blue states, and derailing lifesaving research on everything from cancer to opioid addiction. We all need to speak out to save lives.
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Reposted by Karine G Le Roch
Atul Gawande @agawande.bsky.social · 02/02/2025
“Two-thirds of the staff of the President’s Malaria Initiative…the largest donor to anti-malaria programs…worldwide, have been fired…incl some of the most senior and respected scientists working on malaria control in the world.”
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Eric Topol @erictopol.bsky.social · 08/02/2025
15%. In 2018, 10% was tried, but it was blocked by Congress. www.nytimes.com/2017/09/11/u... www.science.org/content/arti...
science.org
NIH plan to reduce overhead payments draws fire
White House wants to reduce indirect payments from 28% to 10%
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Science Magazine @science.org · 08/02/2025
The National Institutes of Health plans to severely cut the percentage of its grant money that can be used for overhead costs rather than research.
scim.ag
NIH slashes overhead payments for research, sparking outrage
Move to cut indirect cost rate to 15% could cost universities billions of dollars
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Reposted by Karine G Le Roch
Science Magazine @science.org · 06/02/2025
The dismantling of USAID could disrupt many clinical trials and wipe away U.S. “soft power” in developing countries, scientists warn.
scim.ag
'It’s tectonic:’ U.S. foreign aid freeze deals a blow to research around the globe
Dismantling of USAID could disrupt many clinical trials and wipe away U.S. “soft power” in developing countries, scientists warn
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Reposted by Karine G Le Roch
Keystone Symposia @keystonesymposia.bsky.social · 01/02/2025
A round of applause 👏 for the Keystone Symposia award recipients at our joint conference on RNA Mediated Regulation of Immunity / Non-Coding RNA Biology! Thanks to National Human Genome Research Institute,@bwfund.bsky.social, & the @niaidnews.bsky.social. #KeystoneSymposia #keystoneconferences
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Reposted by Karine G Le Roch
Science Magazine @science.org · 31/01/2025
The chaos triggered by President Donald Trump’s executive orders banning federal funding for diversity and other topics continues to shake the National Institutes of Health and other health agencies. scim.ag/3EjJGag
scim.ag
NIH is purging Trump-targeted programs—but is sparing existing grants, so far
Chaos extends to CDC, which is shuttering websites in “data apocalypse”
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Reposted by Karine G Le Roch
WHO @who.int · 30/01/2025
🧵 🎉 Congratulations #Niger for eliminating Onchocerciasis, commonly known as river blindness, the first country in the African Region to do so bit.ly/40Ur7lV 1/4
A young African girl in a red dress holding a fish by a river. Her feet is in the water.
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Anna Bower @annabower.bsky.social · 31/01/2025
I’m sad to learn that my law school classmate, Kiah Duggins, died in the DC plane crash last night. Kiah was an exceptionally talented civil rights lawyer and aspiring legal scholar. I hope you’ll read about her work and the causes she cared about, some of which I’ll 🧵 below. What an immense loss
A professional headshot of a woman in a navy suit with long black hair.
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Reposted by Karine G Le Roch
IRD @ird-fr.bsky.social · 30/01/2025
#Communiqué 🗞️ La Guinée célèbre aujourd’hui l’élimination de la maladie du sommeil (aussi appelée trypanosomiase humaine africaine – #THA) comme problème de #santé publique. #WorldNTDDay ℹ️ www.ird.fr/loms-valide-... @dndi.org @who.int @pasteur.fr
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Reposted by Karine G Le Roch
Karine G Le Roch @karineleroch.bsky.social · 29/01/2025
Register! womeninmalaria.es/wim-conferen...
womeninmalaria.es
WiM Conference - Women in Malaria
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Karine G Le Roch @karineleroch.bsky.social · 29/01/2025
Register! womeninmalaria.es/wim-conferen...
womeninmalaria.es
WiM Conference - Women in Malaria
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Karine G Le Roch @karineleroch.bsky.social · 26/01/2025
Ready for it! www.keystonesymposia.org/conferences/...
keystonesymposia.org
Non-Coding RNA Biology: New Roles and Diversity | Keystone Symposia
Join us at the Keystone Symposia on Non-Coding RNA Biology: New Roles and Diversity, January 2025, in Keystone, with field leaders!
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Reposted by Karine G Le Roch
ParasitesRule @parasitesrule.org · 21/01/2025
The MPM XXXVI page is now live. Sept 14th to Sept 18th. More updates will be coming soon. Check it out on the parasitesrule.com website. Organized this year by Richarch McCulloch @rmc9z.bsky.social, Photini Sinnis, Marc-Jan Gubbels, Deepali Ravel & Omar Harb @omarharb.bsky.social
parasitesrule.com
Molecular Parasitology Community
The MPM XXXVI website is now online
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Reposted by Karine G Le Roch
Vaughn Cooper @vscooper.micropopbio.org · 23/01/2025
I am confident that scientific societies will play an unusually important role in the coming years. If you are a microbiologist of any kind, please consider joining @asm.org if you haven't already. There are many ways to get involved, including advocacy. To learn more: asm.org/About-ASM/Vo...
asm.org
Volunteer With ASM | Overview
ASM volunteer opportunities range from speaking with legislators about funding research during ASM's annual Hill Day, to writing articles for asm.org, to serving on committees and the Board of Directo...
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Anand Ray @anandray.bsky.social · 24/01/2025
Preprint of our honey bee paper out in ELIfe elifesciences.org/reviewed-pre...
elifesciences.org
Machine learning of honey bee olfactory behavior identifies repellent odorants in free flying bees in the field
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Reposted by Karine G Le Roch
Jon Cooper @joncooper-us.bsky.social · 23/01/2025
Wow — there are now more than 29 MILLION users on Bluesky! Spread the word!! 💙🦋 bsky-users.theo.io
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Karine G Le Roch @karineleroch.bsky.social · 24/01/2025
My first post on this platform! As a scientist who love science, this EO is hard to comprehend! www.science.org/content/arti...
science.org
Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring
Researchers facing “a lot of uncertainty, fear, and panic”
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Reposted by Karine G Le Roch
RitaTewari @ritatewari.bsky.social · 06/12/2024
Delighted to share our first manuscript on @bsky.app on a novel SUN1-ALLAN complex in Plasmodium MTOC and NE organization. Many thanks @zeeshanm.bsky.social; @eelcotromer.bsky.social; @ryanase.bsky.social ; Tony; Sarah; David F; Karine; Igor; Cyrille; Declan. Link: www.biorxiv.org/content/10.1...
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Mathieu Gissot @gissotlab.bsky.social · 02/01/2025
The best way to start 2025: our latest work is out in #PLOSPathogens. It discusses ApiAP2 transcription factors and daughter cell assembly in T. gondii. A work spearheaded by @be-maanasa.bsky.social with the contribution of @mudiyamv.bsky.social dx.plos.org/10.1371/jour...
dx.plos.org
Cascading expression of ApiAP2 transcription factors controls daughter cell assembly in Toxoplasma gondii
Author summary Toxoplasma gondii is a is a unicellular eukaryotic pathogen that infects a wide range of animals. Pathogenesis of this parasite relies on its ability to rapidly proliferate and dissemin...
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Maryse Lebrun @lebrunlab.bsky.social · 16/01/2025
Delighted to share our study on a major Toxoplasma virulence factor that prevents lytic host cell death. Many thanks to @parafrap.bsky.social for support, constructive reviews and all labs involved: Melissa Lodoen, Hiba El Hajj, @gissotlab.bsky.social, Karine Le Roch Link : rdcu.be/d6m3G
rdcu.be
The Toxoplasma rhoptry protein ROP55 is a major virulence factor that prevents lytic host cell death
Nature Communications - Ruivo et al uncover a Toxoplasma survival mechanism conserved across different cell types and species. By repressing NF-kB activation and lytic host cell death pathways, the...
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SheinerLab @sheinerlab.bsky.social · 20/01/2025
Remember learning that ribosomes are made of 1 large subunit RNA + 1 small subunit RNA? Well, some cells defy this rule, and the most extreme case is Toxoplasma which makes its mitoribosome from >50 RNA pieces! Wanna know how? Read below
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