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Jonathan VanRyzin

@jwvanryzin.bsky.social
556 followers 119 following 15 posts

Postdoc at UNC Chapel Hill | Astrocytes and microglia in development and disease | Stress, Social Behavior, Addiction | On the job market

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Reposted by Jonathan VanRyzin
Caroline Menard @caromenard666.bsky.social · 03/02/2026
Out in its final form! Congratulations @sejpaton.bsky.social @jolusolo.bsky.social Alice Cadoret @adelinec.bsky.social @luisa-binder.bsky.social Béatrice Daigle @laura-mb.bsky.social Laurence Dion-Albert @katarzynaadudek.bsky.social @manonlebel5.bsky.social 🥂🧠🤓 www.nature.com/articles/s41...
nature.com
Environmental enrichment and physical exercise prevent stress-induced social avoidance and blood-brain barrier alterations via Fgf2 - Nature Communications
Chronic stress disrupts the brain vasculature and contributes to mood disorders, but mechanisms of resilience remain unclear. Here, the authors show that enriched environments increase astrocytic Fgf2...
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Catherine Dulac @dulaclab.bsky.social · 13/12/2025
New paper alert!!...🤩 Led by @blogeman.bsky.social, we identify how cell type-specific hormonal responses in the hypothalamus tunes parenting behavior in males and females 🐭🧠🍼. Highlights in thread 👇 1/6 www.biorxiv.org/content/10.6...
biorxiv.org
Cell Type-Specific Hormonal Signaling Configures Hypothalamic Circuits for Parenting
Parenting behavior emerges from hormonally sensitive circuits, but how distinct circuit components are affected by, and contribute to, sex and state dependent changes in infant caregiving remains uncl...
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PNIRS @pnirs.bsky.social · 11/12/2025
📣#TellUsAboutYourResearch: Meet Dr. Jonathan VanRyzin @jwvanryzin.bsky.social, a postdoctoral fellow at the University of North Carolina! His research investigates how microglia and astrocytes sculpt neural circuits underlying motivated behavior. #MeetThePNIResearcher
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Jonathan VanRyzin @jwvanryzin.bsky.social · 12/12/2025
😍😍😍
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Reposted by Jonathan VanRyzin
Kristen Montgomery @kristenmontgomery.bsky.social · 12/12/2025
A favorite recent image of some busy microglia, lovingly named the Rat King (yellow CD68, pink Iba1, blue DAPI) for my first #FluorescenceFriday
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Tom Kash @superkash.bsky.social · 05/12/2025
In @elife.bsky.social: Sex differences in BNST signaling and BNST CRF in fear processing doi.org/10.7554/eLif... Official version finally out. Thank you to reviewers, made it better!
doi.org
Sex differences in BNST signaling and BNST CRF in fear processing
Critical differences in how the BNST responds to different types of fear across male and female mice.
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Reposted by Jonathan VanRyzin
PNIRS @pnirs.bsky.social · 03/12/2025
Join us for the next live webinar in the #PNIRS Presents Speaker Series: 🗣️ Dr. Laura Fonken from UT Austin 🪧 "Microglial rhythms contribute to sex-specific changes in behavior across the lifespan" 📆 Tues. Dec. 9th, 11:00am ET RSVP is FREE and you don't need to be a member! pnirs.org/pnirs-presents
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eLife @elife.bsky.social · 03/12/2025
Jumping spiders can recognise one another. This ability to learn, remember and represent images is quite surprising for such a tiny-brained animal! buff.ly/dCkwPr0
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Amanda Kentner @mindfulrat.bsky.social · 17/11/2025
Very glad to share our newest paper published in Molecular Psychiatry: Investigating milk-derived extracellular vesicles as mediators of maternal stress and environmental intervention www.nature.com/articles/s41... fun collab w/ @jordanmarrocco.bsky.social. Please enjoy! #OpenAccess #MaternalHealth
nature.com
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Omer Ali Bayraktar @bayraktarlab.bsky.social · 11/11/2025
Which human brain circuits are implicated in neurodevelopmental conditions? We bridged human genetics, spatial transcriptomics and neurodevelopment to discover the convergence of autism-associated genes in the developing human thalamus! www.biorxiv.org/content/10.1...
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Vered Kellner @vkellner.bsky.social · 11/11/2025
Check out our new review article from my lab: doi.org/10.1111/jnc....
doi.org
Crosstalk Between Astrocytes and Inhibitory Neurons During Maturation: Emerging Mechanisms and Functional Implications
In this review, we discuss the development and maturation of inhibitory neurons and astrocytes and how early developmental activity in the brain might promote the interactions between these cell type...
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Reposted by Jonathan VanRyzin
Will Giardino @willgiardino.bsky.social · 11/11/2025
New preprint from the lab! We identified Vipr2-expressing BNST neurons as a distinct subpopulation of the oval nucleus that promotes feeding, is activated by food restriction, is non-overlapping with appetite-suppressing PKC delta neurons, and projects to PSTN & PVN hypothalamic feeding centers.
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41... #blueprint 1/7
nature.com
Estrogen modulates reward prediction errors and reinforcement learning - Nature Neuroscience
Dopamine encoding of reward prediction errors naturally fluctuates over females’ reproductive cycles with estrogenic signaling due to reduced expression of dopamine reuptake proteins.
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Nature @nature.com · 11/11/2025
Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology go.nature.com/4p2hyua
go.nature.com
How genetically encoded sensors have lit up neuroscience
Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology — although important caveats remain.
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Jonathan VanRyzin @jwvanryzin.bsky.social · 11/11/2025
Can say that I've done this previously with my rats and it's 100% worth it to "hear" them giggle with a USV microphone 🤣
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Reposted by Jonathan VanRyzin
Ben Saunders @bensaunders.bsky.social · 15/10/2025
Check out our latest, online now at @sfnjournals.bsky.social www.jneurosci.org/content/earl...
jneurosci.org
Superior colliculus projections drive dopamine neuron activity and movement but not value
To navigate dynamic environments, animals must rapidly integrate sensory information and respond appropriately to gather rewards and avoid threats. It is well established that dopamine (DA) neurons in...
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Reposted by Jonathan VanRyzin
Blanca Díaz Castro @bdiazcastro.bsky.social · 06/11/2025
Finally it’s here! 🌟⬇️ www.nature.com/articles/s41... I’m sooo excited to share our latest article led by Steve Hill and Isabel Bravo-Ferrer 1- How does the vasculature communicate with astrocytes? 2- Is this communication dependent to what happens in the body. 3- Is it relevant to human diseases?
nature.com
Fig. 1: Establishment of methods to identify astrocyte endfoot proteins. | Nature Communications
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Ryan McLaughlin @ryanmcpickle.bsky.social · 11/09/2025
Science friends! I need your help. We have a Neurophotometrics FP system that we are having trouble integrating with behavioral tracking software for annotation purposes. For example, we want to align fluorescence with open/closed arm exploration in the EPM. Can you help us out??
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Travis Faust @travisfaust.bsky.social · 12/09/2025
Thrilled to share our new paper @cp-cell.bsky.social: “Microglia–astrocyte crosstalk regulates synapse remodeling via Wnt signaling.” This work demonstrates the necessity of glia–glia communication and coordination during synapse remodeling. 🔗 www.cell.com/cell/fulltex... Faust et al., Cell 2025
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Bertoglio lab (FMC/UFSC) @bertogliolab.bsky.social · 26/08/2025
Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities www.sciencedirect.com/science/arti...
sciencedirect.com
Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities
Prenatal stress (PNS) is a well-established risk factor for psychiatric disorders, yet the underlying neurobiological mechanisms remain unclear. Here,…
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Reposted by Jonathan VanRyzin
Maxwell Madden @maxwellmadden.bsky.social · 21/08/2025
Excited my PhD work in @brianmathur.bsky.social’s lab is now published and available!
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Elena Blanco-Suárez @eblancosuarez.bsky.social · 14/08/2025
If you have a "recently" (in the last 2 years) published paper with a preprint available, I’d love to hear from you! All neuroscience topics are welcome. 🙏🏼 Thank you!
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Jonathan VanRyzin @jwvanryzin.bsky.social · 13/08/2025
I am SO EXCITED to share this one! The latest paper from the lab is online in @cp-cellreports.bsky.social. We show microglia prune NAc astrocyte processes during abstinence from cocaine-self ad which drives later drug seeking behavior. www.sciencedirect.com/science/arti...
sciencedirect.com
Abstinence from cocaine self-administration promotes microglial pruning of astrocytes, which drives cocaine-seeking behavior
Rodent drug self-administration leads to a compromised ability of nucleus accumbens astrocytes to maintain glutamate homeostasis as well as to reducti…
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Jonathan VanRyzin @jwvanryzin.bsky.social · 06/08/2025
Incredibly grateful to be one of the 2025 BBRF Young Investigator Grant awardees! Thank you to @bbrfoundation.bsky.social and to my mentors for their support along the way!
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Dr. Cate Peña @cate-cholamine.bsky.social · 06/08/2025
Review now out in @npp-journal.bsky.social! Epigenetic regulation of brain development, plasticity, and response to early life stress rdcu.be/ezzYq
rdcu.be
Epigenetic regulation of brain development, plasticity, and response to early-life stress
Neuropsychopharmacology - Epigenetic regulation of brain development, plasticity, and response to early-life stress
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Neuropsychopharmacology @npp-journal.bsky.social · 05/08/2025
#ThisWeekInNPP This study explored how prenatal & postnatal THC exposure affects 🧠 development & social behavior in 🐭, highlighting an impact on microglial phagocytosis in the developing amygdala in a sex-specific & timing-dependent manner ⏲️ / @jwvanryzin.bsky.social
nature.com
Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala - Neuropsychopharmacology
Neuropsychopharmacology - Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala
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Jonathan VanRyzin @jwvanryzin.bsky.social · 29/07/2025
Excited to see our most recent project published in @npp-journal.bsky.social ! We show that the timing of THC exposure during development—prenatal vs. postnatal—leads to opposite effects on social behavior and microglial function in the amygdala. Timing matters! www.nature.com/articles/s41...
nature.com
Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala - Neuropsychopharmacology
Neuropsychopharmacology - Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala
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pegmccarthy.bsky.social @pegmccarthy.bsky.social · 23/07/2025
Excited to announce our latest production! @jwvanryzin.bsky.social @aemarquardt.bsky.social @um-mind.bsky.social www.nature.com/articles/s41...
nature.com
Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala - Neuropsychopharmacology
Neuropsychopharmacology - Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala
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Jonathan VanRyzin @jwvanryzin.bsky.social · 22/11/2024
Happy #FluorescenceFriday ! Sharing one of my favorite images I've taken of microglia phagocytosis featuring a neuron whose DAPI is all too happy to be eaten.
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Reposted by Jonathan VanRyzin
Shane Liddelow @liddelowsa.bsky.social · 14/11/2024
go.bsky.app/Lyzro3M !WELCOME! thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list. apologies for missing many of you - please do reply to get added and remember to repost so the newbies can find us!
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Jonathan VanRyzin @jwvanryzin.bsky.social · 14/11/2024
I've been trying something a bit different on the microscope lately. Looking at ways we can model physical interactions of astrocytes with specific neural circuits across development.
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Jonathan VanRyzin @jwvanryzin.bsky.social · 12/11/2024
Finally made the migration! To any new faces, I'm Jon and I'm a postdoc at UNC studying microglia, astrocytes, brain development, stress, and addiction. I'm also on the job market!
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