Subiculum, the primary output structure of the hippocampus, remains an enigmatic structure in spatial processing. Here the authors reimagine subicular spatial responses as emerging from behaviour and ...

L’une des plus coûteuses et fraudogènes niches fiscales à destination des entreprises pourrait être revue par le gouvernement, suscitant des cris d’orfraie du patronat. ...

Bicanski proposes an algorithm and neural mechanisms for the iterative construction of abstract cognitive maps via non-local inference. Map positions are triangulated and memorized by a set of extant ...

Cohen and Gong provide a practical guide to voltage imaging, covering voltage indicators, gene expression strategies, instrumentation, instrument control software, data analysis algorithms, and experimental protocols. Signal-to-noise ratios and sources of artifacts are discussed in detail.

Ce texte est ma courte contribution aux assises pour l’Université et pour la Recherche (3-4/9/2026), concernant le financement de la recherche. La recherche repose sur deux principes indissoc…

The authors use recurrent neural networks to predict how structured prior experience shapes neural dynamics as mice learn flexible timing strategies during complex context-dependent behavior.

Using in vivo whole-cell recordings during goal-directed navigation, Bhatia, Adel, and Grienberger identify plateaus as a prominent feature of subiculum activity. These events preferentially occur nea...

Associational memory is critically dependent on the CA3 recurrent circuit, at the centre of the hippocampal system. While diversity amongst CA3 pyramidal neurons (PNs) has been long reported, the prin...

To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...

médecine/sciences (M/S), revue internationale dans le domaine de la recherche biologique, médicale et en santé

The neuromodulator octopamine, the insect counterpart to norepinephrine, helps flies get their bearings in an unfamiliar environment.

Biological sciences; Behavioral neuroscience; Laboratory animal science

Entomology; Biophysics; Complex systems

Tau pathology spreads cell to cell in Alzheimer’s disease, but the molecular mechanisms are unclear. This study found that the capsid-forming protein Arc binds and packages tau into extracellular vesi...

De novo mutations in the Stxbp1 gene lead to Munc18.1 haploinsufficiency and are a major cause of neurodevelopmental disorders. Because Munc18.1 is essential...

A brain–machine interface is used in monkeys to investigate the biophysical underpinnings of cortical high gamma-band activity, a signal that is often studied in the context of many brain functions.