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Mélanie BROSSET-HECKEL

@melaniebh.bsky.social
14 followers 26 following 1 posts

PostDoc at INMED☀️ PhD: consequences of maternal high fat diet on early hippocampal development and NDD in offspring PostDoc: STXBP1 haploinsufficiency related to epileptic encephalopathy leads to channelopathies ? Electrophysiology on slices, behavior

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Reposted by Mélanie BROSSET-HECKEL
Federation of European Neuroscience Societies - FENS @fens.org · 25/05/2026
🔸 Her team investigates the neural mechanisms linking emotional contagion to behavioural adaptation, with a particular focus on the serotonin system as a key integrator of social and emotional information.
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Reposted by Mélanie BROSSET-HECKEL
Federation of European Neuroscience Societies - FENS @fens.org · 25/05/2026
🧠 Sarah Mondoloni | FENS-EJN Awards Lecture 🌟 At #FENS2026, join Sarah Mondoloni on 6 July! 🔬 Sarah Mondoloni is a neuroscientist at the Institut de Neurobiologie de la Méditerranée (INMED) in Marseille, France. Meet all the speakers 👉 buff.ly/wQ8V4Ha @ejneuroscience.bsky.social
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Mélanie BROSSET-HECKEL @melaniebh.bsky.social · 24/06/2026
A little late to announce it, but I'm very happy to have contributed to this article ! If you LOVE electrophysiology, this is for you ! www.frontiersin.org/journals/cel...
frontiersin.org
Frontiers | Early and transient increase in cortical pyramidal cell excitability and delayed alteration of evoked synaptic transmission and t-SNARE proteins content in the hippocampus and neocortex of...
De novo mutations in the Stxbp1 gene lead to Munc18.1 haploinsufficiency and are a major cause of neurodevelopmental disorders. Because Munc18.1 is essential...
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Reposted by Mélanie BROSSET-HECKEL
Jerome Epsztein @jeromeepsztein.bsky.social · 11/09/2025
Happy to share our new paper with Mathilde Nordlund and Julie Koenig out @currentbiology.bsky.social. We used virtual reality in mice to study hippocampal distance coding. Our results suggest a primary contribution of grid cells to distance over cue-dependent place cell coding. shorturl.at/63yFo
Color-coded mean firing rate maps of place fields detected in the forth trials (left, sorted by the location of place fields peak) and back trials (right, sorted according to firing order in the forth trials) of all bidirectional cells recorded in the track with objects (top) or without objects (bottom). The color represents the intensity of the mean firing rate in a given bin normalized to the maximum mean firing rate (peak rate) in each direction. Note that in the CP condition, the mean firing map in one direction is the mirror image of the mean firing map in the other direction, indicating strong distance coding.
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Reposted by Mélanie BROSSET-HECKEL
NeuroMarseille-NeuroSchool @neuromarseille.bsky.social · 24/06/2025
🏆 Grand Prix NRJ – Institut de France** Félicitations à Olivier Manzoni (NeuroMarseille / Inserm), co-lauréat pour ses travaux sur les effets des addictions maternelles sur la progéniture 🧠 Avec Peter Vanhoutte, distingué pour ses recherches sur l’addiction.
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Reposted by Mélanie BROSSET-HECKEL
Stina Börchers, PhD @stinaborchers.bsky.social · 18/06/2025
🧠🍽️ A "hunger switch" in the nose? Smelling food activates a pathway from the olfactory bulb to medial septum glutamatergic neurons in mice, triggering anticipatory satiety: making them feel full before eating. This circuit works in lean mice but is disrupted in obesity. #neuroskyence 🧪
nature.com
A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism
The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.
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Reposted by Mélanie BROSSET-HECKEL
Lex Kravitz @kravitzlab.com · 19/06/2025
This was a really fun project: We blocked obesity in mice by making them do a tiny bit of work for their food. www.sciencedirect.com/science/arti...
sciencedirect.com
A simple action reduces high-fat diet intake and obesity in mice
Diets that are high in fat cause overeating and weight gain in multiple species of animals, suggesting that high dietary fat is sufficient to cause ob…
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Reposted by Mélanie BROSSET-HECKEL
INMED @inmed.bsky.social · 28/05/2025
New work from Elodie Fino's team Striatal SOM interneurons set the pace of early motor learning by shaping initial learning through network-level remodeling with S. Rotariu, G. Zalcman and @elofino.bsky.social @inmed.bsky.social @univamu.fr @insermpacacorse.bsky.social shorturl.at/zxpwW
sciencedirect.com
Somatostatin interneurons select dorsomedial striatal representations of the initial motor learning phase
The dorsomedial striatum (DMS) is an associative node involved in the initial formation of motor sequences and the adaptation of ongoing actions. Duri…
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Reposted by Mélanie BROSSET-HECKEL
Audrey Dussutour @docteur-drey.bsky.social · 04/03/2025
Chloé et Angelo, stagiaires de 4e et 3e se sont demandés si le blob pouvait "grimper" pour obtenir des flocons d'avoine collés au plafond. Réponse : no problémo!
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Reposted by Mélanie BROSSET-HECKEL
Eleonora Ambrad @norambr.bsky.social · 13/03/2025
www.univ-amu.fr/en/public/ac...
univ-amu.fr
Safe Place For Science: Aix Marseille University ready to welcome American scientists | Aix Marseille Université
In a context where some scientists in the United States may feel threatened or hindered in their research, our university is announcing the launch of the Safe Place For Science program, dedicated to w...
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Reposted by Mélanie BROSSET-HECKEL
Science News @scinews.bsky.social · 04/03/2025
A comprehensive review of genetic causes of obesity. @world-j-pediatr.bsky.social "Genetic causes, including leptin-melanocortin pathway disruptions, contribute to childhood obesity, requiring early genetic testing and personalized treatment approaches." link.springer.com/article/10.1...
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Reposted by Mélanie BROSSET-HECKEL
JB Manent @jbmanent.bsky.social · 11/03/2025
Want to do a PhD? Are you interested in cortical development and how altered cortical development leads to epilepsy? 🧠⚡ Come and work with us in Marseille at @inmed.bsky.social Apply to Neuroschool PhD program for international students @neuromarseille.bsky.social www.fens.org/careers/job-...
fens.org
PhD position - Multimodal profiling of epilepsy onset and progression in preclinical models of cortical malformations - Federation of European Neuroscience Societies
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Reposted by Mélanie BROSSET-HECKEL
Université de Bordeaux @univbordeaux.bsky.social · 10/03/2025
Début @semaineducerveau.bsky.social 🧠 ce soir (18h30) avec une conférence « Malbouffe et horaires décalés chez l’adolescent : quels effets sur la mémoire ? » : www.u-bordeaux.fr/ev...
u-bordeaux.fr
Semaine du cerveau «Malbouffe et horaires décalés chez l’adolescent : quels effets sur la mémoire ?»
L'adolescence est une période charnière où l'on commence à faire ses propres choix alimentaires et à adopter un rythme de vie autonome, pouvant amener à de mauvaises habitudes de vie comme des horaires décalés de repas et de sommeil. Cette liberté peut avoir un impact significatif sur le poids des adolescents et, dans certains cas, conduire à l'obésité et provoquer des troubles mnésiques. Le projet de recherche MAORI se penche sur cette problématique en explorant comment une mauvaise alimentation et une dérégulation de la prise alimentaire peuvent affecter leur cerveau encore en pleine maturité, et avoir des effets leur mémoire.
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Reposted by Mélanie BROSSET-HECKEL
Semaine du Cerveau @semaineducerveau.bsky.social · 21/02/2025
Lors de cette conférence, le Dr Sébastien Bouret expliquera les mécanismes en jeu dans le développement du cerveau qui pourraient prédisposer à l'obésité. 📍 Pour en savoir plus, rendez-vous à Cannes, le 11 mars à 14h30 ➕ tinyurl.com/399btfvj #SDC2025
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Reposted by Mélanie BROSSET-HECKEL
Semaine du Cerveau @semaineducerveau.bsky.social · 05/03/2025
Quels sont les liens entre la malbouffe, les horaires décalés et la mémoire des adolescent·e·s ? 🍔 🕐 Découvrez comment une mauvaise alimentation et une dérégulation de la prise alimentaire peuvent affecter un cerveau en plein développement 📍Le lundi 10 mars à 18h30 à Bordeaux ➕ tinyurl.com/2ft8aenx
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