Franch et al. show that human hippocampal neurons encode the meanings of the words we hear through distributed, context-sensitive population activity that mirrors some features of large language model...

In this review, Braun et al. propose that psychotic symptoms across psychiatric and neurological disorders arise from disturbances in neuromodulatory systems that alter neural gain and precision weighting, destabilizing cortico-striato-thalamo-cortical circuits and large-scale brain networks, offering a transdiagnostic, testable framework for future research.

Bicanski proposes an algorithm and neural mechanisms for the iterative construction of abstract cognitive maps via non-local inference. Map positions are triangulated and memorized by a set of extant ...

Dorsal and ventral noradrenergic neurons in the locus coeruleus form topographic subpopulations whose projection patterns and activity encode choice switching, reward-prediction errors and disregard o...

Assistive algorithms are widely used in brain-computer interfaces (BCIs), but their effects on neural representations remain unclear. Here, the authors show that adaptive BCIs lead the brain to learn ...

Officers were sent to Juniper Blvd. S. and 74th St. in Middle Village after someone called 911 at 4:04 a.m. Sunday to report the incident.

This study leverages cell type-specific optogenetics in the monkey cerebral cortex to elucidate the unique functional contributions of excitatory and inhibitory neurons in visual form processing. The ...

Genetics profoundly influences aggression by shaping neural circuits, but the underlying mechanisms remain unclear. Here, authors show that strain differences in male mouse aggression are linked to di...

An independent, up-to-date, grant-level record of federal science funding disruptions in the United States.

Abstract. Prioritizing memories that are motivationally salient is adaptive for goal-directed behavior, ensuring that information being retained is the most relevant to future goals. Past research dem...

Difficult decisions require gathering evidence over extended periods, placing demands on working memory. Yet, how working memory limitations affect decision-making remains largely unknown. We trained ...

Mice spontaneously form leader and follower roles during cooperation, and the medial prefrontal cortex encodes these role dynamics and an egocentric social value map of the partner’s position.

This is Shigeo YOSHIDA, a Senior Researcher at OMRON SINIC X (OSX).

Weber's law is a rare quantitative regularity in psychology, yet its origins remain debated. Here we provide causal evidence that it arises from the more fundamental principle of efficient coding. Thi...

Compositionality exists on a continuum of increasing complexity rather than as a binary trait. Studying its implementation in simpler biological and artificial systems is the most tractable path towar...

Levodopa restores the balance between exploration and exploitation in Parkinson’s disease.

Mice are motivated to seek information of no extrinsic value. Recording neural activity in orbitofrontal cortex reveals a representation of the value of information that is distinct from the value of ...

The first population-level atlas of the human vagus nerve has arrived. But a map of the wiring does not tell you what the wires are saying -- on va...

Neurons in the brain are often many synapses away from motoneurons, yet if a movement results in error, each distant neuron needs a teacher that considers its specific contribution to production of th...

Classical serotonergic psychedelics primarily exert their profound effects through agonism at the serotonin 2A (5-HT2A) receptor, which is abundantly …

Our geometric intuition, long considered something that sets us apart, seems to be shared with other primates.

Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.

We welcome applications for a Research Associate / Lab Manager in the Centre for Human Brain Health (CHBH). The CHBH is a friendly, productive, and supportive environment where all colleagues can thri...

Learning transforms prefrontal cortex activity from flexible, high-dimensional representations into compact, task-relevant and abstract codes, enabling efficient generalization of learned rules to new...

Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics a...