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Jaeseung Hahn

@jaeseunghahn.bsky.social
296 followers 69 following 448 posts

molecular hacker, (accidental) synthetic biologist, SciComm fledgling, and postdoc on the faculty job market | Dear AI crawlers, please don't waste energy scraping my ramblings here | Dear Marvel, please don't sue me

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Jaeseung Hahn @jaeseunghahn.bsky.social · 29/09/2026
The emergence of complex structures from simple components is so elegant that it seems like magic. The folks from the @weilgroup.bsky.social and Landfester group show that these 9-aa-long peptides self-assemble into multichannel nanofibrils with hexagonal pores! 🔯🤯 www.nature.com/articles/s41...
nature.com
Sequence-encoded hexagonal lattices in multichannel peptide nanofibrils - Nature
Nine-residue peptides can encode discrete interaction motifs that direct the formation of hexagonal pores, which hierarchically tile into laterally expandable multichannel nanofibrils with defined top...
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Erik Poppleton @poppleton.phd · 09/09/2026
New size record in DNA origami nanopores! 🧬
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Jaeseung Hahn @jaeseunghahn.bsky.social · 11/08/2026
The Trump administration is dismantling one of America's greatest strategic assets: its scientific workforce scienceandfreedomalliance.substack.com/p/the-trump-...
scienceandfreedomalliance.substack.com
The Trump administration is dismantling one of America's greatest strategic assets: its scientific workforce
By Jenna Norton and Max Stier
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veikkolinko.bsky.social @veikkolinko.bsky.social · 07/08/2026
In our new insight article, we summarize the current status of the hybrid RNA/DNA origami structures 🧬, their design principles/parameters, properties, and their potential use in gene delivery. doi.org/10.18609/nuc...
doi.org
Hybrid RNA/DNA origami nanostructures
Within the past 20 years, structural DNA nanotechnology has evolved from simple DNA tiles composed of a few strands to more advanced DNA origami nanostructures composed of dozens of unique strands. Me...
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Erik Poppleton @poppleton.phd · 25/07/2026
This is an excellent development in the blind testing field! Good luck to the competitors 🧬
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veikkolinko.bsky.social @veikkolinko.bsky.social · 11/06/2026
New results! 🧬
doi.org
DNA origami uptake in Y-79 retinoblastoma cells driven by oligolysine coating
DNA origami nanoparticles (DONs) are attractive nanocarriers of controllable size, shape and addressability that have potential for treating eye diseases by overcoming ocular barriers. However, subopt...
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Ákos T Kovács @evolvedbiofilm.bsky.social · 05/06/2026
@natmicrobiol.nature.com Editorial: Communicating microbiology effectively www.nature.com/articles/s41...
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Björn Högberg @bjornhogberg.bsky.social · 02/06/2026
My department is recruiting! Come and start your new lab at the Karolinska Institutet in Stockholm! ki.varbi.com/en/what:job/...
ki.varbi.com
Assistant Professor in Biomedical Science
Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universities,
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Itai Yanai @itaiyanai.bsky.social · 22/05/2026
NYC Postdocs: join us for this month's Postdoc Night Science event! Having a science buddy is crucial for the creative process. So this time we're meeting at a bar near Union Square for some science buddy "speed dating". RSVP: tinyurl.com/3t5us6hp!
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Erik Poppleton @poppleton.phd · 01/04/2026
In addition to carrying genetic data, DNA and RNA can also be designed to fold into 'molecular breadboards' with nanometer addressability. To enable tightly-packed RNA origami, we developed a new motif, the αKL, which we're excited to share in our preprint!🧬🧪 1/🧵 www.biorxiv.org/content/10.6...
Scientific diagram showing the alphaKL. Left panels shows various atomic force microscope images of structures built using the motif, while the right panel shows a computer rendering of the motif.
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DISCO: DNA Infrastructure for Storage and COmputation. @disco-eu.bsky.social · 27/02/2026
🧬💻We are hiring! universityvacancies.com/maynooth-uni...
universityvacancies.com
Senior Research Fellow (in DNA computing, DNA data storage and DNA nanostructures) (Specified Purpose Contract) Hamilton Institute / Maynooth University | University Vacancies Ireland
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Jaeseung Hahn @jaeseunghahn.bsky.social · 11/02/2026
This is happening today! If you are postdoc AND in NYC (even if you are from non-NYC institutions), you should join. It's always a good time at NYC postdoc night science.
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Johanna Joyce @johannajoyce.bsky.social · 11/02/2026
Today is the #InternationalDayofWomenandGirlsinScience - celebrating women across our @helloeacr.bsky.social community 🙌 From Board members across Europe to the #EACR HQ team and the scientists we serve worldwide, women play a central role in advancing cancer research every day #WomeninScience 👩🏻‍🔬🧪
linkedin.com
#internationaldayofwomenandgirlsinscience #eacr #womeninscience | Johanna Joyce
Today is the #InternationalDayofWomenandGirlsinScience - a moment to recognise and celebrate women across all of the #EACR community 🙌 From Board members working together across Europe, to the dedic...
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Jaeseung Hahn @jaeseunghahn.bsky.social · 11/02/2026
Just let creative people create 🤷‍♂️
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Jasmine Crockett @jasmineforus.bsky.social · 09/02/2026
Bad Bunny understood the assignment…
A picture of bad bunny with the word love
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Jeremy Berg @jeremymberg.bsky.social · 09/02/2026
My quote of the day Benito Antonio Martínez Ocasio
I've always been surrounded by many great people and professors, but my family, especially my mom who was a teacher, was the person who encouraged me to study and pushed me to continue. When we're young, we don't understand why our parents bug us so much with school and doing homework, but it's a blessing to have that support at home.
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Petr Šulc @petrsulc.bsky.social · 08/02/2026
🧪🧬 You can now play Minecraft with DNA nanotechnology! In our latest preprint we introduce DNA polycubes platform: A modeling driven system, where we use SAT-solvers+multiscale simulations to design 3D finite-size structures that assemble in high yield chemrxiv.org/doi/full/10....
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JungmannLab @jungmannlab.bsky.social · 07/02/2026
Up to 15-fold improvement in protein labeling for DNA-PAINT 🧬🔬. We are excited to present our latest work published in @angewandtechemie.bsky.social! onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Dynamic Binder Exchange Improves Protein Labeling Efficiency in DNA‐PAINT up to 15‐Fold
Dynamic Binder Exchange (DyBE) leverages transient binder–target interactions to enhance labeling efficiency by up to 15-fold in super-resolution microscopy. DyBE maps nanoscale receptor tyrosine kin...
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Jaeseung Hahn @jaeseunghahn.bsky.social · 06/02/2026
Another big step for the DNA nanotech field from the Irvine and Bathe labs! DNA origami-based vaccine platform elicits broadly neutralizing antibodies against HIV with less non-specific, scaffold-targeting antibodies compared to protein-based vaccine platform 🧬🦠👀 www.science.org/eprint/MJ7WF...
science.org
DNA origami vaccines program antigen-focused germinal centers
Priming rare subdominant precursor B cells in germinal centers (GCs) is a central goal of vaccination to generate broadly neutralizing antibodies (bnAbs) against HIV. Multivalent immunogen display on ...
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Kelsey Monson, PhD @kelseymonson.bsky.social · 03/02/2026
What a treat to be interviewed by Dr. @oliverbogler.bsky.social of the @night-science-inst.bsky.social to discuss our NYC Postdoc Chapter! I chat a bit about my career and research, and give some tips and tricks for starting your own Night Science chapter! www.youtube.com/watch?v=4yeO...
youtube.com
A Night Science Chapter for Postdocs: Building Creative Thinking Skills with Kelsey Monson, PhD
YouTube video by Night Science Institute
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Jaeseung Hahn @jaeseunghahn.bsky.social · 05/02/2026
Of course, bacteria have to do something crazy as well because of crazy phages ⚔️🧬🦠👀
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Jaeseung Hahn @jaeseunghahn.bsky.social · 05/02/2026
Rare-earth elements mining phages? Phages keep giving 💎🧬🦠😭
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Itai Yanai @itaiyanai.bsky.social · 03/02/2026
It’s a lonely job, leading a research group (professor, principal investigator, group leader – whatever you call it). You talk all day with everyone, but you’re mostly alone with the doubts and risks of the biggest decisions. Does it have to be though?? podcasts.apple.com/us/podcast/n...
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Itai Yanai @itaiyanai.bsky.social · 02/02/2026
What is a discovery? Why are discoveries so difficult to make? How does Night Science & Day Science capture the process of discovery? What are a few Night Science tools? Can we change the culture of science? Check out my talk at the DAI Science Festival! www.youtube.com/watch?v=e9p0...
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Wiep Klaas Smits (ExpBac/CMAT) @smitslab.bsky.social · 30/01/2026
Sustained in situ protein production and release in the mammalian gut by an engineered bacteriophage www.nature.com/articles/s41...
nature.com
Sustained in situ protein production and release in the mammalian gut by an engineered bacteriophage - Nature Biotechnology
Biologics are delivered to the gut using phage that infects resident commensal bacteria.
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Jaeseung Hahn @jaeseunghahn.bsky.social · 01/02/2026
It's that time of the decade folks. Buckle up for the new installment of the "Hallmarks of cancer" series by Douglas Hanahan 🧐
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Jaeseung Hahn @jaeseunghahn.bsky.social · 01/02/2026
Bacteroides thetaiotaomicron walks into a gut and... senses and reports on the increased osmolality of the gut associated with inflammatory bowel disease and celiac disease through glowing, fluorescent 💩🦠🧬
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Tae Seok Moon @taeseokmoon.bsky.social · 31/01/2026
#SynBYSS conference is scheduled on Jun 8-11, 2026 in Barcelona. Given the 100-year celebration of Architect Gaudi in Barcelona, we suggest early booking of hotels. Details can be found: www.jcvi.org/events/synbyss (speakers, abstract submission & registration) @jcvi.org @marcguellc.bsky.social
jcvi.org
SynBYSS
The International SynBYSS Conference is focused on bringing together the synthetic biology community with the explicit goal of developing young...
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Jaeseung Hahn @jaeseunghahn.bsky.social · 30/01/2026
If I disappear one day...
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Jaeseung Hahn @jaeseunghahn.bsky.social · 30/01/2026
"vibe" coding 😂
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Tae Seok Moon @taeseokmoon.bsky.social · 29/01/2026
#SynBYSS webinar with Prof. Dina Petranovic, PhD, EMBA at DTU - Technical University of Denmark & Dr. Michael Grome at Yale University The talk video is below: www.youtube.com/watch?v=VluK...
youtube.com
SynBYSS webinar with Prof. Dina Petranovic at Technical U. of Denmark & Dr. Michael Grome at Yale U.
YouTube video by TAESEOK Moon
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Andreas Walther @waltherlab.bsky.social · 27/01/2026
🧪🧠 New preprint out! Soft Hardware, Flowing Software We introduce reconfigurable microfluidics as an active control layer for chemical computation. Geometry, and flow, and not molecular redesign, programs function. Great work by Piet! chemrxiv.org/doi/full/10....
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Tae Seok Moon @taeseokmoon.bsky.social · 29/01/2026
Our work on waste plastic polyethylene upcycling is out @cp-trendsbiotech.bsky.social thanks to huge efforts by Yuxin Tian, Seong-Min Cho, Sunkyu Park & Jinjin Diao @ncstate.bsky.social & @jcvi.org supported by NSF Global Center, DOE BER & AIChE Langer Prize! www.sciencedirect.com/science/arti...
sciencedirect.com
Elucidation of odd-chain dicarboxylate metabolism in Acinetobacter baylyi and application to polyethylene upcycling
Polyethylene (PE) is a versatile polymer, but its end-of-life management is challenging due to its recalcitrant structure. We present a promising appr…
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Olivier Borkowski @oborkowski.bsky.social · 26/01/2026
Plasmid mutation rates scale with copy number doi.org/10.1073/pnas...
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Jaeseung Hahn @jaeseunghahn.bsky.social · 27/01/2026
This is some crazy stuff! 🧬🤯
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Jaeseung Hahn @jaeseunghahn.bsky.social · 27/01/2026
This article is now freely available to everyone in PubMed! www.ncbi.nlm.nih.gov/pmc/articles...
ncbi.nlm.nih.gov
Design and Modeling of Biosensor-Driven Encapsulation Systems for Systemic Delivery of Bacterial Cancer Therapy
Advances in synthetic biology continue to potentiate bacterial cancer therapy. Here, we constructed biosensor-driven encapsulation systems for autonomous control of capsular polysaccharides of Escherichia coli Nissle 1917 to improve pharmacokinetic ...
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Erik Poppleton @poppleton.phd · 26/01/2026
Structures of mRNA come to life thanks to some innovative use of DNA-PAINT 🧬
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Jaeseung Hahn @jaeseunghahn.bsky.social · 26/01/2026
I finished @itaiyanai.bsky.social's recommended reading for aspiring scientists. The message feels similar to my recent approach to life: "let good things happen." Life is a random walk, and there is no denying that. We can only seize the moment. Now what? pni.princeton.edu/sites/g/file...
pni.princeton.edu
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SK Winnicki, PhD 🏳️‍⚧️ @skwinnicki.bsky.social · 22/01/2026
Me: "It would take an extremely fascinating new bird fact to distract me from the horrors" New paper: hold my beer Birds are very eye-dependent and eyes usually require a bunch of energy (and oxygen to metabolize it). Bird retinas run oxygen-free though, perhaps to fly extremely high (low O2)!
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Jaeseung Hahn @jaeseunghahn.bsky.social · 25/01/2026
Scientists from University of North Texas and UT Southwestern Medical Center developed a probiotic strain that may help prevent arsenic poisoning! These bacteria can detect arsenite and produce chelators that sequester arsenite. 🦠 www.biorxiv.org/content/10.6...
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Jaeseung Hahn @jaeseunghahn.bsky.social · 23/01/2026
Why does comedy have anything to do with science? My PhD advisor told me that a scientific talk should be prepared like stand-up comedy: every minute detail calculated, practiced, tried, and tweaked. Come to this event and learn how comedy can help creative scientific process! 👇
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Itai Yanai @itaiyanai.bsky.social · 21/01/2026
NYC Postdocs! Interesting in using comedy in the creative scientific process? NYC Postdoc Night Science will have its first 2026 meeting on Feb. 11 at @nyumedpostdocs.bsky.social. I'll lead this with the amazing stand-up comedian Sarah Adelman! Free registration: docs.google.com/forms/d/11Sz...
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Erik Poppleton @poppleton.phd · 22/01/2026
Neat paper! Boosting to the MP feed 🧬
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Jaeseung Hahn @jaeseunghahn.bsky.social · 23/01/2026
I want to thank Prof. @taeseokmoon.bsky.social again for giving me this platform to share my work. As a junior researcher, it is a rare opportunity to have such a large audience. I am truly thankful and delighted for this experience!
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Jaeseung Hahn @jaeseunghahn.bsky.social · 22/01/2026
I will be presenting my work at the interface of nanomedicine and synthetic biology during the SynBYSS webinar today at 11am EST! It will be tough to follow Prof. Hyun Uk Kim, but I will try my best. 🧬💊
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Itai Yanai @itaiyanai.bsky.social · 21/01/2026
As always, our team includes Kelsey Monson, Ramon Massoni-Badosa Jaeseung Hahn and Tim Stearns! @kelseymonson.bsky.social @rmassonix.bsky.social @stearnslab.bsky.social @jaeseunghahn.bsky.social
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Jaeseung Hahn @jaeseunghahn.bsky.social · 21/01/2026
Check out this beautiful work on mammalian wound healing! 🤯
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Jaeseung Hahn @jaeseunghahn.bsky.social · 20/01/2026
Martin Luther King Jr on equality and the status quo open.substack.com/pub/sciencea...
open.substack.com
Martin Luther King Jr on equality and the status quo
From status quo bias, to ‘popularism’ and picking big fights, MLK Jr in Letter From a Birmingham Jail has lessons about politics and society in the Trump era.
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Molpigs @molpigs.bsky.social · 19/01/2026
We just released the latest episode of the Molpigs podcast! This time with Megan Engel, a professor at the University of Calgary who is who uses machine learning to build better molecular models. 🧬 Links to the episode on all major feeds can be found on our website: podcast.molpi.gs/media/engel-...
podcast.molpi.gs
molpigs Podcast | Megan Engel: Harnessing Machine Learning to Build Better Molecular Models
Join us for a conversation with Professor Megan Engel from the University of Calgary about what it takes to build better physical models of molecules. Her work is inspired by the challenges faced by t...
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Stand Up for Science! @standupforscience.net · 19/01/2026
ICE’s actions tear families apart, intimidate communities, & undermine the conditions that make education, research, healthcare, & public trust possible. We’re calling on scientists to join the general anti-ICE strike in Minnesota on January 23rd.
Red protest-style graphic with bold white text reading “Scientists Against ICE.” Below, rows of black human silhouettes stand holding hands. Centered is the Stand Up for Science logo, followed by text: “Calls for a General Strike Jan 23, 2026, Minnesota.” Black starburst shapes frame the sides. Bottom text reads: “Mobilize the fight for science and democracy.”
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