iiinova — where your digital self keeps evolving

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Shawn Douglas @douglaslab.org · 12/10/2026

Gelbox, a gel electrophoresis simulator built by me and @chaimg.bsky.social, now runs in the browser. We've also ported the native app to PC/Win and Apple silicon. Check it out at douglaslab.org/gelbox/

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Jaeseung Hahn @jaeseunghahn.bsky.social · 13/10/2026

This preprint from the @sleimanh.bsky.social group and the Khvorova group reports interesting results on delivery of chemically stabilized RNA junctions carrying siRNA. I have much respect for the researchers pushing in vivo delivery of nucleic acid nanostructures! 🧬 www.biorxiv.org/content/10.6...

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Itai Yanai @itaiyanai.bsky.social · 12/10/2026

Postdoc opening: My lab at NYU Langone Health is looking for a new postdoctoral fellow with wet-lab experience for an exciting project.

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Jaeseung Hahn @jaeseunghahn.bsky.social · 12/10/2026

역시 영화는 조조할인이죠 👍

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Itai Yanai @itaiyanai.bsky.social · 10/10/2026

1. CRISPR came from basic research on bacteria. 2. Optogenetics started with a discovery in algae. 3. The GFP protein comes from jellyfish. The biggest breakthroughs all trace to scientists following their curiosity, and this is one huge reason why we must keep funding basic research!

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Jaeseung Hahn @jaeseunghahn.bsky.social · 06/10/2026

Hahaha I wholeheartedly agree! The third photo with "즐겁다" captures that idea precisely 😂

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Tae Seok Moon @taeseokmoon.bsky.social · 04/10/2026

With Dr. Macalincag, I discuss workforce development & outreach activities, including #SynBYSS webinar & conference series as the director of CIRCLE Global Center supported by NSF. Thank Marisa Rinkus & NSF for the invitation and support. @jcvi.org youtu.be/-3wu6eWE-QE?...

youtu.be

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Jaeseung Hahn @jaeseunghahn.bsky.social · 29/09/2026

Oops, I forgot to tag molecular programming 🧬

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Jaeseung Hahn @jaeseunghahn.bsky.social · 29/09/2026

The press release has a nice graphic that shows how these peptides form honeycomb lattices and nanofibrils! www.mpip-mainz.mpg.de/1192846/PM20...

mpip-mainz.mpg.de

Molecules Build a Honeycomb

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Jaeseung Hahn @jaeseunghahn.bsky.social · 29/09/2026

The emergence of complex structures from simple components is so elegant that it seems like magic. The folks from the @weilgroup.bsky.social and Landfester group show that these 9-aa-long peptides self-assemble into multichannel nanofibrils with hexagonal pores! 🔯🤯 www.nature.com/articles/s41...

nature.com

Sequence-encoded hexagonal lattices in multichannel peptide nanofibrils - Nature

Nine-residue peptides can encode discrete interaction motifs that direct the formation of hexagonal pores, which hierarchically tile into laterally expandable multichannel nanofibrils with defined top...

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Erik Poppleton @poppleton.phd · 09/09/2026

New size record in DNA origami nanopores! 🧬

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Jaeseung Hahn @jaeseunghahn.bsky.social · 01/09/2026

I am sure 짬뽕라면 and 햇반 taste like a dish from a michelin-starred restaurant with that view!

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Jaeseung Hahn @jaeseunghahn.bsky.social · 11/08/2026

The Trump administration is dismantling one of America's greatest strategic assets: its scientific workforce scienceandfreedomalliance.substack.com/p/the-trump-...

scienceandfreedomalliance.substack.com

The Trump administration is dismantling one of America's greatest strategic assets: its scientific workforce

By Jenna Norton and Max Stier

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veikkolinko.bsky.social @veikkolinko.bsky.social · 07/08/2026

In our new insight article, we summarize the current status of the hybrid RNA/DNA origami structures 🧬, their design principles/parameters, properties, and their potential use in gene delivery. doi.org/10.18609/nuc...

doi.org

Hybrid RNA/DNA origami nanostructures

Within the past 20 years, structural DNA nanotechnology has evolved from simple DNA tiles composed of a few strands to more advanced DNA origami nanostructures composed of dozens of unique strands. Me...

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Jaeseung Hahn @jaeseunghahn.bsky.social · 04/08/2026

We gotta appreciate good things in life when we have the opportunity!

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Erik Poppleton @poppleton.phd · 25/07/2026

This is an excellent development in the blind testing field! Good luck to the competitors 🧬

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Jaeseung Hahn @jaeseunghahn.bsky.social · 24/07/2026

Amen to that, and I hope you enjoy the beautiful island and people of Puerto Rico!

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Ákos T Kovács @evolvedbiofilm.bsky.social · 05/06/2026

@natmicrobiol.nature.com Editorial: Communicating microbiology effectively www.nature.com/articles/s41...

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Itai Yanai @itaiyanai.bsky.social · 22/05/2026

NYC Postdocs: join us for this month's Postdoc Night Science event! Having a science buddy is crucial for the creative process. So this time we're meeting at a bar near Union Square for some science buddy "speed dating". RSVP: tinyurl.com/3t5us6hp!

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Erik Poppleton @poppleton.phd · 01/04/2026

In addition to carrying genetic data, DNA and RNA can also be designed to fold into 'molecular breadboards' with nanometer addressability. To enable tightly-packed RNA origami, we developed a new motif, the αKL, which we're excited to share in our preprint!🧬🧪 1/🧵 www.biorxiv.org/content/10.6...

Scientific diagram showing the alphaKL. Left panels shows various atomic force microscope images of structures built using the motif, while the right panel shows a computer rendering of the motif.

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Jaeseung Hahn @jaeseunghahn.bsky.social · 11/02/2026

This is happening today! If you are postdoc AND in NYC (even if you are from non-NYC institutions), you should join. It's always a good time at NYC postdoc night science.

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Jaeseung Hahn @jaeseunghahn.bsky.social · 11/02/2026

Just let creative people create 🤷‍♂️

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Jaeseung Hahn @jaeseunghahn.bsky.social · 09/02/2026

"Discussion: This positive response in the treatment group may be attributed to the increased Coca Cola consumption in mice that took Wegovy pills based on the hypothesis generated by ChatGPT."

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Jasmine Crockett @jasmineforus.bsky.social · 09/02/2026

Bad Bunny understood the assignment…

A picture of bad bunny with the word love

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Jeremy Berg @jeremymberg.bsky.social · 09/02/2026

My quote of the day Benito Antonio Martínez Ocasio

I've always been surrounded by many great people and professors, but my family, especially my mom who was a teacher, was the person who encouraged me to study and pushed me to continue. When we're young, we don't understand why our parents bug us so much with school and doing homework, but it's a blessing to have that support at home.

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Petr Šulc @petrsulc.bsky.social · 08/02/2026

🧪🧬 You can now play Minecraft with DNA nanotechnology! In our latest preprint we introduce DNA polycubes platform: A modeling driven system, where we use SAT-solvers+multiscale simulations to design 3D finite-size structures that assemble in high yield chemrxiv.org/doi/full/10....

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Jaeseung Hahn @jaeseunghahn.bsky.social · 07/02/2026

Congrats to all the authors! It's really cool to see that DNA-PAINT keeps improving 👀

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Jaeseung Hahn @jaeseunghahn.bsky.social · 06/02/2026

Another big step for the DNA nanotech field from the Irvine and Bathe labs! DNA origami-based vaccine platform elicits broadly neutralizing antibodies against HIV with less non-specific, scaffold-targeting antibodies compared to protein-based vaccine platform 🧬🦠👀 www.science.org/eprint/MJ7WF...

science.org

DNA origami vaccines program antigen-focused germinal centers

Priming rare subdominant precursor B cells in germinal centers (GCs) is a central goal of vaccination to generate broadly neutralizing antibodies (bnAbs) against HIV. Multivalent immunogen display on ...

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Kelsey Monson, PhD @kelseymonson.bsky.social · 03/02/2026

What a treat to be interviewed by Dr. @oliverbogler.bsky.social of the @night-science-inst.bsky.social to discuss our NYC Postdoc Chapter! I chat a bit about my career and research, and give some tips and tricks for starting your own Night Science chapter! www.youtube.com/watch?v=4yeO...

youtube.com

A Night Science Chapter for Postdocs: Building Creative Thinking Skills with Kelsey Monson, PhD

YouTube video by Night Science Institute

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Jaeseung Hahn @jaeseunghahn.bsky.social · 05/02/2026

Of course, bacteria have to do something crazy as well because of crazy phages ⚔️🧬🦠👀

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Jaeseung Hahn @jaeseunghahn.bsky.social · 05/02/2026

Rare-earth elements mining phages? Phages keep giving 💎🧬🦠😭

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Itai Yanai @itaiyanai.bsky.social · 03/02/2026

It’s a lonely job, leading a research group (professor, principal investigator, group leader – whatever you call it). You talk all day with everyone, but you’re mostly alone with the doubts and risks of the biggest decisions. Does it have to be though?? podcasts.apple.com/us/podcast/n...

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Jaeseung Hahn @jaeseunghahn.bsky.social · 02/02/2026

Don't judge me Itai: I watched this Youtube video while exercising this morning, and I learned what you do in your Day Science for the first time (very cool!) 😂

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Itai Yanai @itaiyanai.bsky.social · 02/02/2026

What is a discovery? Why are discoveries so difficult to make? How does Night Science & Day Science capture the process of discovery? What are a few Night Science tools? Can we change the culture of science? Check out my talk at the DAI Science Festival! www.youtube.com/watch?v=e9p0...

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Jaeseung Hahn @jaeseunghahn.bsky.social · 01/02/2026

It's not exactly the same, but I try to draw parallels between computer and human languages. There are decent AI translators out there, but it's hard to connect with people when I can't actually speak the language. I think there is something equivalent in coding. I acknowledge the sense of loss 😞

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