Innovative Genomics Institute @innovativegenomics.bsky.social · 20hWe're hiring two research associates to work on our new Advanced Research Projects Agency for Health (ARPA-H) BIOGAMI program studying disordered proteins associated with neurodegenerative diseases. Learn more and see other open positions here: innovativegenomics.org/careers/ 010
Innovative Genomics Institute @innovativegenomics.bsky.social · 12/10/2026New from IGI's Patrick Shih — a novel framework for exploring genome regulation across the evolutionary tree, starring (over 1000) fungi. Learn more: innovativegenomics.org/news/machine… 0111
Innovative Genomics Institute @innovativegenomics.bsky.social · 09/10/2026Most neurodegenerative diseases begin with misfolded proteins. A new project funded by the ARPA-H BIOGAMI program seeks to prevent neurodegenerative diseases by learning the language of disordered proteins in human cells at scale. Learn more: ow.ly/fLju50ZW7EC 140
Innovative Genomics Institute @innovativegenomics.bsky.social · 07/10/2026🧠 ICYMI: IGI's Martin Kampmann's team uncovered a novel pathway to clear toxic #tau buildup in the brain, which could lead to a new strategy to treat dementias like Alzheimer's disease. Read more in his Cell - a Cell Press journal paper from earlier this year: ow.ly/2HFA50ZU3hu 041
Innovative Genomics Institute @innovativegenomics.bsky.social · 05/10/2026📣New paper alert! From Pam Ronald's lab, "Signaling by a tyrosine-sulfated peptide balances growth and osmotic stress response in rice." 🌾Read here: ow.ly/RHLK50ZU32z 031
Reposted by Innovative Genomics InstituteUC Berkeley @ucberkeleyofficial.bsky.social · 01/10/2026UC Berkeley has once again been named the top public university in North America in the 2027 Times Higher Education World University Rankings. This adds to the growing list of #1 rankings Berkeley has earned this year. bit.ly/4delZyInews.berkeley.eduUC Berkeley is the No. 1 public university in North America in Times Higher Education rankings - Berkeley NewsBerkeley tied for ninth worldwide in the publication’s 2027 assessment of a record 2,297 universities. 12810
Innovative Genomics Institute @innovativegenomics.bsky.social · 30/09/2026🧬 Out recently in Nature, IGI Investigator Yun S. Song has shared a new language model that can detect overlooked gene variants that impact human health. Learn more about how the Song lab is using #AI to investigate the human genome: ow.ly/44os50ZLxsk 021
Innovative Genomics Institute @innovativegenomics.bsky.social · 28/09/2026IGI Affiliate Ksenia Krasileva on evolutionary design and innate #immunology. Join us today at 2 PM Pacific, in Berkeley or on Zoom! More info here: endpoints.news/in-a-changed-world-f… 020
Innovative Genomics Institute @innovativegenomics.bsky.social · 28/09/2026The 2026 UC Regents Innovation Awards honor two of IGI's Investigators! Fyodor Urnov for his contributions to #CRISPR medicine & Sue Lynch for her work on how the infant gut #microbiome. Read more: www.universityofcalifornia.edu/news… 120
Innovative Genomics Institute @innovativegenomics.bsky.social · 24/09/2026Predicting how #RNA folds would be a valuable tool for scientists, but #AI has not been able to crack the problem. A team at the IGI made significant progress on two key hurdles: limited structural data, and the fact that RNA can take on multiple shapes. Read more: ow.ly/Yjgo50ZJcU3 0117
Reposted by Innovative Genomics InstituteMoi Expósito-Alonso (MOILAB) @mexpositoalonso.bsky.social · 21/09/2026 📣 We are looking for a PhD student in 2027! Interested in studying rapid evolutionary dynamics of species in changing climates? Apply to the MOI LAB by Nov 19! Flyer below & tinyurl.com/flyerphdmoilab @ucberkeleyofficial.bsky.social @innovativegenomics.bsky.social @hhmi-science.bsky.socialtinyurl.com2027_PhD_RapidEvolutionGenomicsEcology-MoiLab_Berkeley-HHMIPhD positions: Rapid evolutionary genomics in plants Moi Exposito-Alonso Lab — www.moilab.science Assistant Professor, Freeman Hrabowski Scholar HHMI · Department of Integrative Biology · Innovative G... 03547
Innovative Genomics Institute @innovativegenomics.bsky.social · 21/09/2026As a postdoc, Phillip Cleves became the first person to genetically modify #coral. Now, he's trying to figure out how to save reefs and the magnificent ecosystems they host. Learn more about IGI's newest investigator: innovativegenomics.org/news/saving-… 082
Reposted by Innovative Genomics InstituteCarl Zimmer @carlzimmer.com · 17/09/2026I wrote about what came before CRISPR 4 billion years ago: a war among viruses. Gift link: nyti.ms/3TBq4q0nyti.msThe Next Gene-Editing Technology May Also Be the Oldest (Gift Article)Scientists have discovered a powerful gene-targeting system in viruses. Billions of years old, VIPR seems to predate CRISPR and may be even more powerful. 114351
Innovative Genomics Institute @innovativegenomics.bsky.social · 17/09/2026Before #CRISPR, there was VIPR — a tool viruses used to battle each other with a never-before-seen genetic coding system, uncovered by researchers in the Doudna Lab. Read more here: ow.ly/KblS50ZOxwQ #AI #LanguageModel #RNA 0179
Innovative Genomics Institute @innovativegenomics.bsky.social · 16/09/2026The latest in our Inside Genomics short video series — IGI researchers Sue Lynch at UCSF The Benioff Center for Microbiome Medicine & Ben Rubin Rubin Lab UC Berkeley are creating a new way to prevent & treat childhood #asthma by editing the #microbiome. Watch here: ow.ly/abyU50ZGLAR 010
Innovative Genomics Institute @innovativegenomics.bsky.social · 09/09/2026🧬 Out today in Nature, IGI Investigator Yun S. Song has shared a new language model that can detect overlooked gene variants that impact human health. Learn more about how the Song lab is using #AI to investigate the human genome: ow.ly/44os50ZLxsk 022
Reposted by Innovative Genomics InstituteCongresswoman Lateefah Simon @replsimon.bsky.social · 08/09/2026It was an honor to meet the eight brilliant HBCU undergraduate students who spent the summer at @innovativegenomics.bsky.social labs across the UC system at part of the UC-HBCU Rising Stars program! They are working on the cutting edge of technology. 1225
Innovative Genomics Institute @innovativegenomics.bsky.social · 08/09/2026Out today in Nature Nanotechnology, a Q&A with IGI's Niren Murthy on his new way to engineer lipid nanparticles (LNPs) for safer genome editing. Read it here: innovativegenomics.org/news/safer-l… 011
Innovative Genomics Institute @innovativegenomics.bsky.social · 04/09/2026Predicting how #RNA folds would be a valuable tool for scientists, but #AI has not been able to crack the problem. A team at the IGI made significant progress on two key hurdles: limited structural data, and the fact that RNA can take on multiple shapes. Read more: ow.ly/Yjgo50ZJcU3 052
Reposted by Innovative Genomics InstitutePlant Biotechnology Journal @plantbiotechj.bsky.social · 03/09/2026📝 BRIEF COMMUNICATION 📝 Targeted Knockout of CYP79A1 Reduces Cyanogenic Potential in Grain Sorghum - Groover et al. 🔗 doi.org/10.1111/pbi.... #plantscience 🧪 @evangroover.bsky.social @savagecatsonly.bsky.social @innovativegenomics.bsky.social @natureatcal.bsky.social @berkeleymcb.bsky.social 033
Innovative Genomics Institute @innovativegenomics.bsky.social · 03/09/2026Thanks to Proceedings of the National Academy of Sciences for highlighting our work on reducing methane emissions frow cows! This work is led by IGI Investigators Ermias Kebreab and Matthias Hess The Hess Lab @ UC Davis. Read the article: www.pnas.org/doi/10.1073/pnas.26265… 010
Innovative Genomics Institute @innovativegenomics.bsky.social · 01/09/2026#Asthma is one of the most common childhood diseases. IGI researchers Sue Lynch at UCSF The Benioff Center for Microbiome Medicine & Ben Rubin Rubin Lab UC Berkeley are creating a new way to prevent & treat asthma by editing microbes. More in our new Inside Genomics video! ow.ly/abyU50ZGLAR 030
Reposted by Innovative Genomics InstituteRubin Lab @therubinlab.bsky.social · 31/08/2026Happy Monday! ☀️ On the last day of August, the Rubin Lab presents a researcher interview. We sat down with @leosong.bsky.social, co-first author of this paper, at @innovativegenomics.bsky.social! 🎥🧬 Hear more about the science directly from one of the researchers behind the study! 123
Innovative Genomics Institute @innovativegenomics.bsky.social · 28/08/2026Stay up-to-date with the Cleves lab at @pcleves.bsky.social! 🪸 010
Innovative Genomics Institute @innovativegenomics.bsky.social · 28/08/2026🫁 New from IGI's Sue Lynch: "Upper airway microbiome interacts with GSDMB and ORMDL3 asthma risk SNPs to influence early-life wheeze risk." Read here: www.sciencedirect.com/science/artic… 010
Innovative Genomics Institute @innovativegenomics.bsky.social · 27/08/2026A decade ago, Phil Cleves became the first person to genetically modify #coral. Now, he's trying to figure out how to save reefs and the magnificent ecosystems they host from #ClimateChange. Learn more about IGI's newest investigator: ow.ly/fK9F50ZG9s5 Video by @shumpeim.bsky.social 1174
Innovative Genomics Institute @innovativegenomics.bsky.social · 24/08/2026This summer, the UC-HBCU Rising Stars program hosted 8 talented undergrads from HBCUs at IGI labs across the University of California where they did cutting-edge genomic research. In August, students presented their work at a showcase with Jennifer Doudna and CA Congresswoman Lateefah Simon! 022
Innovative Genomics Institute @innovativegenomics.bsky.social · 19/08/2026Premiering tonight on @pbs.org, Resolve to Solve shares the story of how red seaweed is being used to reduce #methane emissions from cows, featuring IGI's Ermias Kebreab of @ucdavis.bsky.social! Preview here: www.pbs.org/video/cow-bu...pbs.orgResolve to Solve with Miles O'Brien | Seaweed Reduces Cow Methane | Episode 1Cow burps are heating the planet. One dairy farmer’s seaweed fix might cool it down. 031
Innovative Genomics Institute @innovativegenomics.bsky.social · 17/08/2026Out now in Nature, IGI researchers based at UCSF and the Gladstone Institutes use a new kind of #CRISPR screening and uncover two gene edits that could make #cancer #immunotherapies more effective for solid tumors. Learn more: ow.ly/MZwa50ZAFMq 030
Innovative Genomics Institute @innovativegenomics.bsky.social · 13/08/2026Out recently in Science Magazine, Doudna lab researchers Petr Skopintsev, Isabel Esain Garcia, PhD, (pictured) and Evan DeTurk describe a new #AI-assisted method for designing genome editors beyond those found in nature. Read more in this article from Fierce Biotech: ow.ly/LZVx50ZtB9y 040
Innovative Genomics Institute @innovativegenomics.bsky.social · 11/08/2026Job opening at the IGI's Plant Genomics & Transformation Facility at UC Berkeley: Assistant / Associate Specialist – Plant Transformation & Genome Editing ow.ly/7htY50ZyBqg #CRISPR 🌱🧬 0615
Innovative Genomics Institute @innovativegenomics.bsky.social · 11/08/2026We're excited to officially welcome UC San Diego as an IGI partner campus! We're working to jointly develop cutting-edge genomic tools for addressing large-scale challenges in health and the environment. Read more about our plans: ow.ly/My0h50Zp8Lj 032
Reposted by Innovative Genomics InstituteUC Berkeley School of Public Health @publichealth.berkeley.edu · 06/08/2026Could #CRISPR safely curb #InvasiveSpecies? 🐀 Professor John Marshall & @innovativegenomics.bsky.social researchers modeled Y-linked genome editors—a breakthrough technique to safely suppress invasive rodents—without the spread of gene drives or the hazards of rodenticide. ow.ly/pniz50ZvZksow.lyA new approach to controlling invasive rodent populations with CRISPRA new paper models a new approach to controlling rodent populations: Y-linked genome editors, or YLEs. 021
Reposted by Innovative Genomics InstituteZehan Zhou @zehanzhou.bsky.social · 05/08/2026We are PUBLISHED!!! Our mechanistic work on how CRISPR-Cas ancestors unwind DNA and how this can be used to engineer hypercompact plant editors can now be found on Mol Cell- if you are interested in what defines a good genome editor, this read is for you 😎 🔗 www.sciencedirect.com/science/arti...sciencedirect.com 12012
Innovative Genomics Institute @innovativegenomics.bsky.social · 06/08/2026Out recently in Nature, a perspective piece on medical genome standards from IGI's Jennifer Doudna, Fyodor Urnov, Alex Marson, Brad Ringeisen, and collaborators. 🧬 Read here: ow.ly/HSXz50Zn0z7 020
Innovative Genomics Institute @innovativegenomics.bsky.social · 03/08/2026Managing invasive species... with genome editing? 🐀 In a recent paper, IGI researchers design a new approach to controlling invasive rodent populations: Y-linked genome editors. Read more: ow.ly/gB9L50Zs8oh 000
Reposted by Innovative Genomics Institutemarialukarska.bsky.social @marialukarska.bsky.social · 30/07/2026Our ProteinGuide paper is finally out! Thanks to all the co-authors @junhaobearxiong.bsky.social, @ishangaur.bsky.social, @hnisonoff.bsky.social, @loltrogge.bsky.social, @jlistgarten.bsky.social, @savagecatsonly.bsky.social! @innovativegenomics.bsky.social www.nature.com/articles/s41...nature.comProperty guidance for protein sequence generative models with ProteinGuide - Nature BiotechnologyOn-the-fly conditioning of pretrained protein generative models guides protein generation toward specific properties. 075
Innovative Genomics Institute @innovativegenomics.bsky.social · 29/07/2026🌱🌍 Published in Nature Reviews Bioengineering, "Genome engineering of plant photosynthesis for carbon sequestration" from IGI researchers from co-first authors Evan Groover and Flora Zhiqi Wang, and the Savage Lab, Niyogi & Lemaux labs! Read here: www.nature.com/articles/s44222-026-… 011
Innovative Genomics Institute @innovativegenomics.bsky.social · 27/07/2026A new multi-institutional initiative funded by ARPA-H through its THRIVE program is developing affordable gene-editing therapies for inborn errors of immunity in children. The award of up to $27.7M supports a platform approach to rapidly treat inborn errors of immunity: ow.ly/1MfE50ZsZEh 043
Reposted by Innovative Genomics InstitutePrateek Verma @prateekverma.bsky.social · 25/07/2026Our new paper on Y-linked CRISPR editors for invasive rodent control is featured by @innovativegenomics.bsky.social. innovativegenomics.org/news/a-new-a... #CRISPR #RodentControlinnovativegenomics.orgA New Approach to Controlling Invasive Rodent Populations with CRISPRA New Approach to Controlling Invasive Rodent Populations with CRISPR - Innovative Genomics Institute (IGI) 062
Reposted by Innovative Genomics InstituteNature @nature.com · 17/07/2026Scientists have harnessed AI models to create synthetic CRISPR proteins that edit the genome more efficiently than those seen in nature go.nature.com/4f8AN3ngo.nature.comCRISPR gets a power boost from AI-designed ‘molecular scissors’Researchers used artificial intelligence to design functional CRISPR enzymes not seen in nature. 13715
Innovative Genomics Institute @innovativegenomics.bsky.social · 24/07/2026In a new paper, IGI researchers at UC Berkeley & UC San Diego develop a novel approach to controlling invasive rodent populations: Y-linked genome editors, combining scalability with a level of control that has previously been difficult to achieve: ow.ly/8mMx50Zs8of 🧪 062
Reposted by Innovative Genomics Institutemarialukarska.bsky.social @marialukarska.bsky.social · 24/07/2026I’m happy to share our pre-print exploring the activity and specificity trade-offs in adenine base editors. Thanks to my amazing co-authors Luke Oltrogge, @hnisonoff.bsky.social, and all the other contributors @jlistgarten.bsky.social @savagecatsonly.bsky.social @innovativegenomics.bsky.social 🧵1/7biorxiv.orgActivity and specificity trade-offs in adenine base editorsAdenine base editors (ABEs) are CRISPR effectors that introduce A-T to G-C transitions in the genome using a nucleotide deaminase fused to a Cas protein. ABEs have been evolved to have very high editi... 1158
Innovative Genomics Institute @innovativegenomics.bsky.social · 23/07/2026At the IGI, we're using #robotics to accelerate research in critical areas like #Parkinson's disease. Learn more about one of our favorite robots and how IGI's Hanqin Li, Tomy Tran, and Dirk Hockemeyer are changing neurodegenerative disease research: ow.ly/RpMM50Zm85m 022
Innovative Genomics Institute @innovativegenomics.bsky.social · 20/07/2026We're thrilled to officially welcome UC San Diego as an IGI partner campus! We're working to jointly develop cutting-edge genomic tools for addressing large-scale challenges in health and the environment. Read more about our plans: ow.ly/My0h50Zp8Lj 030
Reposted by Innovative Genomics InstituteBel Esain @isabelesain.bsky.social · 17/07/2026So excited to see our paper out in Science! Beyond grateful to my co-leads @petrskopintsev.bsky.social @evandeturk.bsky.social, all co-authors & collaborators, everyone in Doudna lab, and @innovativegenomics.bsky.social Being EsAIn in the DouDNA lab, it couldn't have been any other way ✨ 0103
Innovative Genomics Institute @innovativegenomics.bsky.social · 16/07/2026Out today in @science.org, Doudna lab researchers describe an #AI-assisted method for designing enhanced genome editors, testing close to 2000 in lab. Read more: innovativegenomics.org/news/ai-desi...innovativegenomics.orgAI-Assisted Technique Allows Scientists to Design New, Functional Genome Editors Beyond What Can Be Found in NatureAI-Assisted Technique Allows Scientists to Design New, Functional Genome Editors Beyond What Can Be Found in Nature - Innovative Genomics Institute (IGI) 1135
Reposted by Innovative Genomics InstituteKWS Group @kwsgroup.bsky.social · 16/07/2026🎧 Listening tip! Jennifer Doudna, Nobel laureate and #CRISPR co‑developer, discusses how #GenomeEditing supports the development of more resilient and nutritious crops, while also promoting broad access & public dialogue 🌱 ow.ly/Yb3v50ZjZ24ow.lyWhat’s the Future of Gene Editing? | Quanta MagazineIn the first episode of the new season of ‘The Joy of Why,’ Nobel Laureate Jennifer Doudna discusses how she discovered CRISPR’s genome-editing power, the breakthroughs and hurdles during its explosive growth, and what lies ahead for this groundbreaking technology. 056
Innovative Genomics Institute @innovativegenomics.bsky.social · 14/07/2026Out recently in Nature, new research from Jennifer Doudna, postdoc @jingkunzeng.bsky.social, and collaborators shows a #CRISPR-based method for selectively killing "undruggable" #cancers by recognizing cells with cancer-causing mutations and shredding their DNA. Learn more: ow.ly/NRss50Z8tQK 172
Innovative Genomics Institute @innovativegenomics.bsky.social · 13/07/2026Just out from IGI's Jennifer Doudna, Fyodor Urnov, Alex Marson, Brad Ringeisen, and collaborators, a new Nature perspective piece on medical genome standards. 🧬 Read here: ow.ly/HSXz50Zn0z7 061