iiinova — where your digital self keeps evolving

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

1/23 I have fantastic news! I am truly honored to have been awarded an Emmy Noether-Grant by @dfg.de @uni-muenster.de Since most of you are not from Germany, I will use the following posts to explain what this Program is, who Emmy Noether was and what my group in Münster will be doing. #cellbio

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Maik Bischoff @maikbischoff.bsky.social · 17/07/2026

I feel honored that my Perspective article with @mayorlab.bsky.social on collective cell migration has been featured in this special collection. Many thanks to the curators, @wumin-lab.bsky.social and Gabriele Stephan, as well as @jcb.org rupress.org/jcb/article/... #CellBio #CellMigration

A collage of figures in the perspective article.

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Mathieu Preußner @mathpreu.bsky.social · 13/03/2026

Just combed through my old data… et voilà: a tooth of the gill comb. 🐟✨ #FluorescenceFriday #zebrafish #DevBio #SciArt

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Maik Bischoff @maikbischoff.bsky.social · 05/03/2026

1/10 I am truly honored to receive the Hilde Mangold Award from @gfeev.bsky.social! Mangold’s classic transplantation experiments transformed developmental biology and our understanding of self-organization. I am grateful to be associated with this legacy!

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Rare Disease Day Official @rarediseaseday.bsky.social · 28/02/2026

🌍 It’s #RareDiseaseDay 2026! 💜 Today we stand with the 300 million people living with a rare disease. Together, we’re showing our colours, raising awareness, and inspiring change by talking about what equity means to us. 👉 Read more: go.rarediseaseday.org/NEWS

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Masai Thibault @thibaultmasai.bsky.social · 26/01/2026

🎉New paper (co-author) in Reproduction 🎉 We characterize human QRICH2, a sperm-specific, conserved protein essential for normal sperm structure and function, with potential as a non-hormonal male contraceptive target. Check the full article 👉 doi.org/10.1093/repr... #MaleContraception #ReproBio

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Reproduction Alliance @repro-alliance.bsky.social · 09/02/2026

🔬Join our #ReproductionMS seminar with Dr. @maikbischoff.bsky.social on "Coiling a Duct: How Mesenchymal Cells Sculpt Male Reproductive Organ Architecture" this Wednesday, 11 February 12pm CET. DM for Zoom details.

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Reposted by Dr. Ina Klockner🧬👩‍🔬🔬

Max Planck Institute for Heart and Lung Research @mpi-hlr.bsky.social · 27/01/2026

🧬 𝗡𝗲𝘄 𝘆𝗲𝗮𝗿, 𝗻𝗲𝘄 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗵𝗼𝗿𝗶𝘇𝗼𝗻𝘀! 🧠❤️ Two new research groups have joined our institute – and we’re excited to welcome them! 𝗣𝗦: 𝗞𝗮𝗿𝗶𝗻 𝗶𝘀 𝗵𝗶𝗿𝗶𝗻𝗴! Take a look at her job openings here: lnkd.in/gGQimf8

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Dr. Ina Klockner🧬👩‍🔬🔬 @inaklockner.bsky.social · 15/01/2026

PhD position available 🔬📝 🔥last day to submit your application! stellen.uni-muenster.de/jobposting/d...

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Dr. Ina Klockner🧬👩‍🔬🔬 @inaklockner.bsky.social · 12/01/2026

New biosensor💥 🎯precisely measures endogenous UBE3A activity with super high sensitivity 📌providing a powerful tool for studying Angelman syndrome & advancing therapeutic development for UBE3A-related disorders link to study: www.sciencedirect.com/science/arti...

sciencedirect.com

A luminescence-based biosensor to measure endogenous UBE3A activity

Loss- and gain-of-function (LOF and GOF) mutations in the E3 ubiquitin ligase UBE3A cause distinct neurodevelopmental disorders. The AZUL domain of UB…

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Reposted by Dr. Ina Klockner🧬👩‍🔬🔬

Ariel Levine @ariellevine.bsky.social · 08/01/2026

Excited to share @rbrianroome.bsky.social ‘s beautiful paper on development of the dorsal horn of the mouse spinal cord @science.org This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down. www.science.org/doi/10.1126/...

science.org

Ontogeny of the spinal cord dorsal horn

The dorsal horn of the mammalian spinal cord is organized into laminae where each layer is populated by different neuron types, has distinctive circuit connections, and plays specialized roles in beha...

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Tzviya Zeev-Ben-Mordehai @tzviyazbm.bsky.social · 31/07/2025

I am happy our recent study on the human sperm head-tail junction is now online. We find that SUN5 form an hexagonal lattice at the nuclear membrane, rationalising how mutations in SUN5 lead to infertility. Great work of @cryonas.bsky.social ! www.biorxiv.org/content/10.1...

biorxiv.org

SUN5 forms a regular protein lattice reinforcing the sperm head-tail junction

Linker of nucleo- and cytoskeleton (LINC) complexes reside in the nuclear envelope, the double-membrane surrounding the nucleus, where they establish a physical bridge between nucleus and cytoplasm. L...

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Maik Bischoff @maikbischoff.bsky.social · 06/01/2026

There is still over a week left to apply. Please send your documents to maik.bischoff@uni-muenster.de

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SfN Journals @sfnjournals.bsky.social · 11/11/2025

#eNeuro: Ringelberg et al. identify a key role for excitatory neuron loss of UBE3A in motor, innate, and sleep behavioral phenotypes of Angelman syndrome model mice. doi.org/10.1523/ENEURO.0453-24.2025

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The EMBO Journal @embojournal.org · 22/12/2025

Hong Cheng and collaborators show how alternative polyadenylation can facilitate muscle differentiation and regeneration: 3’UTR shortening of differentiation-gene mRNAs alleviates their repression by myomiR muscle-specific miRNAs link.springer.com/article/10.1...

link.springer.com

3′UTR shortening alleviates miRNA repression of mRNAs critical for muscle stem cell differentiation - The EMBO Journal

Alternative polyadenylation (APA) modulates gene expression by altering 3′ untranslated region (3′UTR) length. Although 3′UTR lengthening typically accompanies cell differentiation, we unexpectedly ob...

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Dr. Ina Klockner🧬👩‍🔬🔬 @inaklockner.bsky.social · 05/01/2026

New paper out 🔥! Small promoter, big potential🧬 We show that the ultra-compact Calm1 promoter efficiently targets human neurons in brain organoids and is a promising alternative to hSyn for AAV gene delivery. Huge thanks to everyone who contributed to this work! 🧠 📄: www.nature.com/articles/s41...

nature.com

Compact Calm1 promoter enables AAV mediated neuron-targeted expression in human iPSC-derived brain organoids - Scientific Reports

Scientific Reports - Compact Calm1 promoter enables AAV mediated neuron-targeted expression in human iPSC-derived brain organoids

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Maik Bischoff @maikbischoff.bsky.social · 28/11/2025

1/2 A special #FluorescenceFriday for me! 🌈 Live muscle precursors on a pupal fly testis (Lifeact-eGFP, 🔥-depth-coded). It's special because this is on the poster for the @sfb1348.bsky.social Meeting in May — my first time being featured as a speaker on a poster! 😀 Feeling very grateful & excited!

Crawly cells with a vibe somewhere between morphogenesis and wildfire

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Maik Bischoff @maikbischoff.bsky.social · 27/11/2025

So excited to share this as a new junior PI: My brand-new lab website! 🎉🪰🌀 www.bischofflab.com Please pass it on to young, motivated researchers looking for PhD positions 😊 And for the #FluorescenceFriday community: don’t miss the SciArt Gallery! #CellBio #DevBio #PhDjob #PhDposition #Science

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Mathieu Preußner @mathpreu.bsky.social · 31/10/2025

Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉 Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life 🔗 journals.biologists.com/dev/issue/15... #FluorescenceFriday #LifelongDevSI

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Development @dev-journal.bsky.social · 21/10/2025

A developmental atlas of zebrafish gills links early vascular patterning to adult architecture Read this #LifelongDevSI #OA Research Article by Mathieu Preußner @mathpreu.bsky.social, Virginie Lecaudey @vlecaudey.bsky.social and colleagues: journals.biologists.com/dev/article/...

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Maik Bischoff @maikbischoff.bsky.social · 03/10/2025

My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing 🔵 lifeact & 🔴 RFP-nls Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨ 🔗 www.nikonsmallworld.com/galleries/20... #NikonSmallWorld #Microscopy #ScienceArt

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Reposted by Dr. Ina Klockner🧬👩‍🔬🔬

Maik Bischoff @maikbischoff.bsky.social · 24/09/2025

1/12 A very special moment for me! 🎉 My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes. rupress.org/jcb/article/... #cellbio #devbio #science 🧵for details

Cartoon of a speculative heterogenous cell population performing mesenchymal collective cell migration.

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Reposted by Dr. Ina Klockner🧬👩‍🔬🔬

Journal of Cell Biology @jcb.org · 23/09/2025

New perspective by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/... #CellBio #CellMigration #Morphogenesis #Development #Science

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Angelman Syndrome Foundation @angelmanfoundation.bsky.social · 26/06/2025

We’re excited to announce the launch of our new website at angelman.org! 🎉 Our updated site features easy navigation and filters that help you find the resources, clinics, research, and support you need on any device. Check it out!➡️ angelman.org

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Viroscope @viroscope.bsky.social · 27/06/2025

A Boa Constrictor brain-derived cell expressing a viral glycoprotein (magenta) and stained for actin (yellow) and DNA (white). #FluorescenceFriday

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Maik Bischoff @maikbischoff.bsky.social · 18/06/2025

FINALLY out in #Science Advances! 🎉 3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author! It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀 www.science.org/doi/10.1126/... #DevBio #CellBio #Microscopy

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Marco A. Maximo Prado @maximoprado.bsky.social · 13/06/2025

For #fluorescencefriday the Mesoscopic Integrated NeuroImaging Data (MIND) platform @westernu.bsky.social presents abeta plaques and blood vessels in the 🧠 of our ApoE4 mouse model of AD. 🧪 #clearing #lightsheet 🔬 Courtesy of Arash Salahinejad, Luke Smolders and @shahrzadbahrampour.bsky.social

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Mathieu Preußner @mathpreu.bsky.social · 06/06/2025

1) Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood. #zebrafish #gills #microscopy

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Mathieu Preußner @mathpreu.bsky.social · 11/04/2025

Gills just wanna have #FluorescenceFriday 🎵 Phalloidin reveals the beauty of the filament's distal tip in cleared gills of adult 🦓🐟 #microscopy #devbio #sciart

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Maik Bischoff @maikbischoff.bsky.social · 28/03/2025

I know, it's a bit late for #FluorescenceFriday but I want to share my new banner :D #cellmigration #cellbio #devbio #sciart #microcosm #science

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Tamas Nagy @tamasnagy.com · 22/03/2025

I begrudgingly admit that actin is pretty cool 🤩 🎥 Primary mouse myotubes labeled with Lifeact-mScarlet-I3 (cyan) and H2B-mStayGreen (red). #FluorescenceFriday

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Maik Bischoff @maikbischoff.bsky.social · 11/03/2025

2/4 I chose this picture because I am interested in an old question: How do fly testes obtain their specific shape? In my previous research I learned that muscle precursors shape it, using collective cell migration and alignement to achieve the pattern visible in this picture.

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Rami Major, Ph.D. 🧬✨ @doe-rami.bsky.social · 08/03/2025

Stand up for science Raleigh!! Let’s keep this energy going!!

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Mathieu Preußner @mathpreu.bsky.social · 28/02/2025

Mesonephric glomeruli of #zebrafish for #FluorescenceFriday 🔬 kdrl-mCherry nicely reveals the capillary tuft of the glomerulus. The zebrafish kidney stops developing at the mesonephros stage! It serves as their main kidney structure, and they don't develop a metanephros like humans do.

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Maik Bischoff @maikbischoff.bsky.social · 28/02/2025

For today's #fluorescencefriday I have a riddle 😊. Can anyone who is knowledgeable in #Drosophila #neuroscience tell my what these are? I honestly don't know! Overview picture in the comments-they are from the brain🧠🪰. The marker is lifeact::GFP, depth-coded... #sciart #microscopy #cellbio #cellfy🔬

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Maik Bischoff @maikbischoff.bsky.social · 07/02/2025

An ancient unpublished picture from my PhD #FluorescenceFriday! Drosophila sperm pump depth-coded with muscles (phalloidin=cyan/green) + Dapi (yellow/red). Not confocal but an old Zeiss Apotome - which is still an awesome scope! #sciart #microscopy #bioart #sciart #microscopyart #cellbio #devbio

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Maik Bischoff @maikbischoff.bsky.social · 30/01/2025

Wow! We got the cover! #MBOC #ASCB #CellBio So proud of #TeamTestis. Screening <270 lines for shape defects was a huge team effort! I created this collage from the team’s images from the past 2 years! Depth-color-coded with Fiji. Inspired by late 19th century lithographic animal illustrations.

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Mathieu Preußner @mathpreu.bsky.social · 20/12/2024

🔬My first try on #FluorescenceFriday Nice detail of a tissue-cleared kidney from neonatal mice. -GFP is expressed in podocytes and pericytes. -CD31 antibody highlights the branched blood vessels and glomeruli in red

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Zhixing Chen @zhixingchen2.bsky.social · 19/12/2024

How proximal is proximity labeling❓ Using DNA nanorulers we found that TurboID/BioID are largely contact labeling, while APEX2 also bears a major contact labeling pathway in parallel with diffusive labeling. www.biorxiv.org/content/10.1... Special thanks to @aliceyting.bsky.social for discussions

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Frank Schnorrer @frankschnorrer.bsky.social · 19/12/2024

Muscles growth by sarcomere divisions - how your muscles add new sarcomeres during developmental growth: they divide! Cool collaboration @friedrich-group.bsky.social @raunser-lab.bsky.social @Dirk Görlich @univ-amu.fr @cnrs.bsky.social sciencecast.org/casts/aspy9l... www.biorxiv.org/content/10.1...

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CRISPRGuru @crisprguru.bsky.social · 03/12/2024

For those interested in "Genome editing and CRISPR technologies": (if you are new here at Bluesky), here are the two starter packs... bsky.app/starter-pack... bsky.app/starter-pack...

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Maik Bischoff @maikbischoff.bsky.social · 12/12/2024

Excited to give my 1st talk on an #ASCB meeting about collective #cellmigration in #Drosophila! #cellbio2024 12/16 4pm Room 33B, more info below👇! Next, I'll post about our 2 posters!🪰 Thank you @allysonsgro.bsky.social & Daniel Cohen for this opportunity! #cellbio #devbio @ascbiology.bsky.social

The title of my talk is Plexin/Semaphorn Signaling Orchestrates Collective Cell Migration. It will be on 12/16 at 4PM in Room 33B!

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Maik Bischoff @maikbischoff.bsky.social · 12/12/2024

1/2 #TeamTestis postbac Sarah Clark presents a really cool poster: A large reverse-genetic screen identifies numerous regulators of testis nascent myotube collective #cellmigration and collective organ sculpting Tuesday, Dec 17 1:30 PM P2783, B400 #cellbio #devbio #cellbio2024 #Drosophila

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Maik Bischoff @maikbischoff.bsky.social · 12/12/2024

Next to my talk (12/16 4 pm room 33B), I will present a poster: "Semaphorin/Plexin Antagonism Orchestrates Collective Cell Migration in vivo". Tuesday, Dec 17 11:15 AM. P2780/Board No. B397 I am so excited. I just love ASCB meetings! #cellbio2024 #cellbio #devcell @ascbiology.bsky.social #ASCB

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Dr. Ina Klockner🧬👩‍🔬🔬 @inaklockner.bsky.social · 25/11/2024

Super recent publication: AAV vector-derived elements integrate into Cas9-generated double-strand breaks and disrupt gene transcription #AngelmanSyndrome doi.org/10.1016/j.ym...

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Maik Bischoff @maikbischoff.bsky.social · 03/12/2024

Super proud and honored to give my first #GRC talk at the Directed Cell Migration #GordonConference in Italy January 12-17 www.grc.org/directed-cel... Thank you so much Sally Horne Badovinac and @robinsall.bsky.social for giving me this fantastic opportunity! #cellbio #devbio #cellmigration

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