iiinova — where your digital self keeps evolving

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Andrew Coogan @cooganlab.bsky.social · 30/09/2026

This is a pretty cool paper looking at how/when people attribute poor sleep to the moon/lunar phase. Lunar effects on sleep have been hanging around in the literature for a while without a putative mechanism, but maybe it is psychological rather than physiological. www.mdpi.com/2624-5175/8/...

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Shrew @shrewshrew.bsky.social · 23/09/2026

If there's one thing I know about the brain it's that solving it should be quick and easy

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Heinrich Gompf @hgompf.bsky.social · 04/09/2026

LOL: Does daylight saving time increase traffic crashes? Seasonal confounding and a morning fatality effect Though the comparison might have been better if it'd been LA vs Phoenix vs Dallas: three large cities at roughly the same latitude and car-dependency. www.sciencedirect.com/science/arti...

sciencedirect.com

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Heinrich Gompf @hgompf.bsky.social · 07/08/2026

We have a pool nestled amongst our backyard orchard, and a fridge with an ice maker on the door and a large-ish center island in the kitchen. But we’re still grateful we don’t live in an apartment the size of our current master bathroom + walk-in closet anymore. =UMC UC: what?!?

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BWJones @bwjones.bsky.social · 05/08/2026

One of my favorite things at museums is finding the pineal eye in the skulls of fossils. Once you start looking for them, they are everywhere.

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Ian Hutchins @bihutchins.bsky.social · 29/07/2026

How cost-effective are NIH Extramural vs Intramural mechanisms? We did internal analysis at NIH but never published results. Happy to share some answers: Extramural is better for measures like publications and citations; Intramural is better at basic -> clinical translation doi.org/10.7554/eLif...

doi.org

Comparing the outputs of intramural and extramural grants funded by National Institutes of Health

Funding mechanisms impact the cost effectiveness of the science conducted, as extramural NIH grants to universities excel at producing papers and citations, while intramural NIH hiring more effectivel...

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Heinrich Gompf @hgompf.bsky.social · 26/07/2026

Looks like the missile are flying towards the fighter jets, though it’s unclear in which direction one of those planes is flying. I think Trump is trying to tell us something here.

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Eliot Higgins @eliothiggins.bsky.social · 17/07/2026

Is this translated from the original German? www.whitehouse.gov/releases/202...

Homeland Security Advisor Stephen Miller made clear there must be no retreat: “One of the hallmarks of left-wing violence and terrorism is its completely pre-textual and disingenuous appeal to civil liberties in an effort to shield its own violence… When the leftist — who does not believe in freedom, who does not believe in civil rights, who does not believe in any ordinary notion of justice — protests that we are violating his rights, understand the he is lying to try to persuade people who are not closely following the political scene that some injustice has perpetrated against him. We must stay the course and be completely unflinching in the pursuit of justice against these enemies of civilization.”

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Science Magazine @science.org · 16/07/2026

🎉 Congratulations to Sergey Stavisky, winner of the 2026 Chen Institute and Science Prize for AI Accelerated Research for developing an AI-powered brain-computer interface that can restore communication for people who have lost the ability to speak. Learn more: scim.ag/4pjlckI

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 09/07/2026

Slow Oscillatory Transcranial Direct Current Stimulation during a Restricted Sleep Opportunity Enhances Cognitive Performance during Subsequent Wakefulness www.biorxiv.org/content/10.64898/20…

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Lindsay Schwarz @lindsayschwarz.bsky.social · 15/12/2025

Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at @rhodescollege.bsky.social!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! www.cell.com/cell-reports...

cell.com

Locus coeruleus norepinephrine neurons facilitate orbitofrontal cortex remapping and behavioral flexibility

Ogg et al. use in vivo imaging techniques to record activity in the locus coeruleus (LC) and the orbitofrontal cortex (OFC) during a reversal learning task in freely moving rodents. They show that man...

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PLOS Biology @plosbiology.org · 09/07/2026

The sublaterodorsal tegmental nucleus in the brainstem is a center for #sleep control. This study shows that GABAergic neurons in this region suppress wakefulness, and that perturbing their activity level can regulate sleep attacks in a mouse #narcolepsy model. 🧪 #AcademicSky plos.io/4pchrxE

An illustration of a proposed mechanism by which GABAergic neurons in the sublaterodorsal tegmental nucleus (SLDGABA neurons) suppress wakefulness in healthy and narcoleptic animals. This schematic illustrates how the balance of wake-promoting signals from the lateral hypothalamus (LH) orexin (LHOX) neurons and wake-suppressive signals from the SLDGABA neurons may determine the changes in arousal states. In healthy mice (orexin+/+), the wake-promoting signal mediated by the LHOX neurons predominates over the wake-suppressive signal mediated by the SLDGABA neurons, generating a stable wakefulness. Conversely, in narcoleptic mice (orexin−/−), orexin-mediated wake-promoting signals are absent, allowing the SLDGABA neurons to produce a disproportionately strong suppression of wakefulness, resulting in wake instability seen as sleep attacks.

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Heinrich Gompf @hgompf.bsky.social · 03/07/2026

Ugh. The nylon replacements from Weber didn't work so I bought one of these. Not giving it back, this one works and I pay attention after cleaning to make sure there are no bristles on the grilling surfaces. Ridiculous: millions of these sold and like 3 people had someone incompetent use the grill.

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Christophe 🔬 Leterrier @christlet.bsky.social · 20/06/2026

Nature is healing at the reflection pool I see

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Luke Ontario @coolhand.bsky.social · 12/06/2026

When I’m fully dissociated and I forget to put on my active listening face

A photo of a sea lion holding its head up in a way that makes it look like a bug eyed person with wild air and a frowny facd

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c0nc0rdance @c0nc0rdance.bsky.social · 10/06/2026

The US capital was probably named for PIGEONS. 😲🐦 I'll explain & dive into some etymology. "Pigeon" is from Old French 'pijon', which is from Late Latin: 'pīpiō', an onomatopoeic term for a young chirping bird. The Latin version of "a peep-peep." But Romans had a /different/ name for pigeons.

static.klipy.com

Baby Bird Screaming for Food - Funny Meme

Alt: Baby Bird Screaming for Food, mouth wide open, in a nest made of straw or twigs.

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Heinrich Gompf @hgompf.bsky.social · 03/06/2026

Most mornings, he reads the note that he wrote himself reminding him to go to the doctor and decides that today is the day...

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Heinrich Gompf @hgompf.bsky.social · 28/05/2026

It's all really simple. Just divert all LAX, SFO, SAN, LAS (and to a lesser extent SMF, RNO, PSP, etc.) international arrivals to Sky Harbor and SLC and then make them rent cars to get to their final destinations!

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Heinrich Gompf @hgompf.bsky.social · 13/04/2026

To follow up on this, I've gotten to an age / point in my career where I often look back and am in awe at how far we've progressed. I used to do single-unit recordings of the LC 20+ years ago. Back then, we used to imagine these figures from the little we knew. Brilliant and impressive.

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Jeremiah Cohen @jeremiahycohen.bsky.social · 13/04/2026

Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1

biorxiv.org

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Heinrich Gompf @hgompf.bsky.social · 12/03/2026

How hot is it in Maryland right now? The guy seems to be sweating like crazy. About the same temp here. I’m planting things and spreading compost in the sun and I’m not sweating the way he is.

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Heinrich Gompf @hgompf.bsky.social · 11/03/2026

A direct hit on our two National Clonal Germplasm Repositories would be devastating. Big, if true.

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Heinrich Gompf @hgompf.bsky.social · 09/03/2026

Not sure if we can rename it "The American Gulf" after "Gulf of America" is already taken.

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Jonathan Eisen @phylogenomics.bsky.social · 09/03/2026

I cannot stop thinking of all the amazing and wonderful people I have known from Israel, Iran, Lebanon and other countries caught up in this war. It is people just like them who are being killed and harmed here.

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Heinrich Gompf @hgompf.bsky.social · 08/03/2026

Californians are incorrigible. What stage between "parking" or "the character of the neighborhood" and "we don't need more housing, we need affordable housing!" is "TRAFFIC!!!" at in the kill-development at any cost scale?

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Dr. Becca @docbecca.bsky.social · 08/03/2026

An utterly bleak picture of the future of academic science in America

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Edward Nirenberg @enirenberg.bsky.social · 07/03/2026

I am just now catching up on the fact that the FDA was demanding Uniqure do sham brain surgeries (from what I can tell, comprising simulated burr holes and 10-12 hours of anesthesia) in their placebo arm for their Huntington's therapeutic, and I'm absolutely floored that this was a serious demand.

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Michael Herf @mherf.bsky.social · 05/03/2026

"Lunar gravity predicts sleep timing" - bookmarking this lunar rhythms & sleep paper as interesting. It uses a 30-day rhythm but not the 28-day declination rhythm - a claim of "gravity" should probably use the 28-day one, but I think "phase" should follow 30? europepmc.org/article/med/...

europepmc.org

Europe PMCEurope PMC

Europe PMC is an archive of life sciences journal literature.

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Drug Monkey @drugmonkey.bsky.social · 03/03/2026

Yes! We literally cannot shut up about our work.

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Drug Monkey @drugmonkey.bsky.social · 02/03/2026

$300 Million in jet planes lost to a fuckup. That’s 83 five year NIH R01 grants burned in minutes due to error, aka poor execution of this unnecessary war which serves only to make the world more dangerous.

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Dr. Becca @docbecca.bsky.social · 27/02/2026

Cool cool cool 🫠

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Adrien Peyrache @apeyrache.bsky.social · 27/02/2026

The ratstronaut dataset is available on DANDI! (and analyzed with @pynapple.bsky.social 😍)

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Nature @nature.com · 19/02/2026

A simple blood test might one day serve as a molecular ‘clock’ that predicts not only whether someone will develop Alzheimer’s disease — but when go.nature.com/4kHqfsV

go.nature.com

Blood test holds promise for predicting when Alzheimer's symptoms will start

The Alzheimer’s ‘clock’ could make it easier to treat the disease early, before memory problems appear.

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Heinrich Gompf @hgompf.bsky.social · 17/02/2026

When planting our garden, I sowed year-round wildflower varieties (here = Central Valley) so that bees in hive boxes in the orchards would know to visit anytime for food. Hoping that they'd also pollinate my fruit trees in the spring. Worked fine so far. This is a very cool visualization of that.

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Ian L Morgan @ianlmorgan.bsky.social · 14/02/2026

Definitely a huge win for higher ed. I think it's important to point out that the suit that led to this outcome was brought by *UC faculty and unions* and not the UC system. The academic workers are fighting back, and we should support them.

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Joey Fishkin @fishkin.bsky.social · 14/02/2026

This is a genuinely huge, sweeping victory today for the University of California—or rather, for us, its faculty, acting through our faculty associations, while the UC itself maintained a strict policy of deer-in-headlights silence. The Trump admin has given up its appeal of a powerful injunction:

latimes.com

Trump administration drops appeal of court order blocking $1.2-billion UCLA settlement

The Trump administration dropped its appeal of a major higher education case in which a federal judge blocked its $1.2-billion settlement proposal to UCLA over alleged civil rights violations. It will...

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Richard Huskey @richardhuskey.bsky.social · 11/02/2026

Depressed? Anxious? Lonely? What if mental health doesn’t just result from media use, but shapes how we choose media? In a new preprint, Valerie Klein, @gongxuanjun.bsky.social @aeden.bsky.social and I and I test this using a computational decision-making model: doi.org/10.21203/rs.... 🧵Thread

doi.org

Using the Drift Diffusion Model to Examine Relationships Between Mental Health and Media Selection Dynamics

A substantial body of research has investigated how people’s transient affective state influences their media selection, as well as how selected media influences subsequent affective states. However, ...

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Mohammad Hosseini @mhmdhsini.bsky.social · 03/02/2026

Regardless of your political views or perspectives on the region, this is a moment when simple acts of compassion, such as brief messages of support or offers of collaboration with colleagues based in Iran, can make a meaningful difference. hashtag#science_diplomacy.

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Heinrich Gompf @hgompf.bsky.social · 03/02/2026

If you have a chance to collaborate with an Iranian scientist, do it: I've always been struck by the quality and ingenuity of the work of my colleague/collaborator in Tehran. With devastatingly few resources, he makes big things happen! I wish we have a chance to meet in person one of these days.

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SLEEP and SLEEP Advances @sleepjournals.bsky.social · 02/02/2026

Join us as we post the answers to the #AMA #AskMeAnything with Editors in Chief Drs. Allan Pack (SLEEP) and Sean Drummond (SLEEPAdvances) over the next two weeks! Question 1: What types of paper submissions would you like to see more of in 2026? 📝 🎤See the EICs' responses below!

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