iiinova — where your digital self keeps evolving

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Andrew Coogan @cooganlab.bsky.social · 30/09/2026

This is a pretty cool paper looking at how/when people attribute poor sleep to the moon/lunar phase. Lunar effects on sleep have been hanging around in the literature for a while without a putative mechanism, but maybe it is psychological rather than physiological. www.mdpi.com/2624-5175/8/...

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Shrew @shrewshrew.bsky.social · 23/09/2026

If there's one thing I know about the brain it's that solving it should be quick and easy

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Heinrich Gompf @hgompf.bsky.social · 22/09/2026

He was Telex-ing them? No wonder he couldn't find them!

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Heinrich Gompf @hgompf.bsky.social · 04/09/2026

LOL: Does daylight saving time increase traffic crashes? Seasonal confounding and a morning fatality effect Though the comparison might have been better if it'd been LA vs Phoenix vs Dallas: three large cities at roughly the same latitude and car-dependency. www.sciencedirect.com/science/arti...

sciencedirect.com

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Heinrich Gompf @hgompf.bsky.social · 21/08/2026

That was also my first totality. Was at a ranch near the John Day Clarno unit with a group from Reed College. Mesmerizing!

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Heinrich Gompf @hgompf.bsky.social · 07/08/2026

We have a pool nestled amongst our backyard orchard, and a fridge with an ice maker on the door and a large-ish center island in the kitchen. But we’re still grateful we don’t live in an apartment the size of our current master bathroom + walk-in closet anymore. =UMC UC: what?!?

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Heinrich Gompf @hgompf.bsky.social · 06/08/2026

They’re mainly interested in making sure we can’t re-arm our bases using the straight. In the end, they might go with 1% or less to give Trump a “win.” Might not even have it kick in until after the 60 days. The money would be nice but in the face of us using their waters to attack them…

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BWJones @bwjones.bsky.social · 05/08/2026

One of my favorite things at museums is finding the pineal eye in the skulls of fossils. Once you start looking for them, they are everywhere.

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Ian Hutchins @bihutchins.bsky.social · 29/07/2026

How cost-effective are NIH Extramural vs Intramural mechanisms? We did internal analysis at NIH but never published results. Happy to share some answers: Extramural is better for measures like publications and citations; Intramural is better at basic -> clinical translation doi.org/10.7554/eLif...

doi.org

Comparing the outputs of intramural and extramural grants funded by National Institutes of Health

Funding mechanisms impact the cost effectiveness of the science conducted, as extramural NIH grants to universities excel at producing papers and citations, while intramural NIH hiring more effectivel...

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Heinrich Gompf @hgompf.bsky.social · 01/08/2026

we have one near where we live (NorCal), and it is awesome!

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Heinrich Gompf @hgompf.bsky.social · 26/07/2026

Looks like the missile are flying towards the fighter jets, though it’s unclear in which direction one of those planes is flying. I think Trump is trying to tell us something here.

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Eliot Higgins @eliothiggins.bsky.social · 17/07/2026

Is this translated from the original German? www.whitehouse.gov/releases/202...

Homeland Security Advisor Stephen Miller made clear there must be no retreat: “One of the hallmarks of left-wing violence and terrorism is its completely pre-textual and disingenuous appeal to civil liberties in an effort to shield its own violence… When the leftist — who does not believe in freedom, who does not believe in civil rights, who does not believe in any ordinary notion of justice — protests that we are violating his rights, understand the he is lying to try to persuade people who are not closely following the political scene that some injustice has perpetrated against him. We must stay the course and be completely unflinching in the pursuit of justice against these enemies of civilization.”

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Science Magazine @science.org · 16/07/2026

🎉 Congratulations to Sergey Stavisky, winner of the 2026 Chen Institute and Science Prize for AI Accelerated Research for developing an AI-powered brain-computer interface that can restore communication for people who have lost the ability to speak. Learn more: scim.ag/4pjlckI

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Heinrich Gompf @hgompf.bsky.social · 14/07/2026

America the beautiful...only smaller.

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Heinrich Gompf @hgompf.bsky.social · 09/07/2026

needs a cupholder so the coffee won't spill during an earthquake

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 09/07/2026

Slow Oscillatory Transcranial Direct Current Stimulation during a Restricted Sleep Opportunity Enhances Cognitive Performance during Subsequent Wakefulness www.biorxiv.org/content/10.64898/20…

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Lindsay Schwarz @lindsayschwarz.bsky.social · 15/12/2025

Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at @rhodescollege.bsky.social!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! www.cell.com/cell-reports...

cell.com

Locus coeruleus norepinephrine neurons facilitate orbitofrontal cortex remapping and behavioral flexibility

Ogg et al. use in vivo imaging techniques to record activity in the locus coeruleus (LC) and the orbitofrontal cortex (OFC) during a reversal learning task in freely moving rodents. They show that man...

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PLOS Biology @plosbiology.org · 09/07/2026

The sublaterodorsal tegmental nucleus in the brainstem is a center for #sleep control. This study shows that GABAergic neurons in this region suppress wakefulness, and that perturbing their activity level can regulate sleep attacks in a mouse #narcolepsy model. 🧪 #AcademicSky plos.io/4pchrxE

An illustration of a proposed mechanism by which GABAergic neurons in the sublaterodorsal tegmental nucleus (SLDGABA neurons) suppress wakefulness in healthy and narcoleptic animals. This schematic illustrates how the balance of wake-promoting signals from the lateral hypothalamus (LH) orexin (LHOX) neurons and wake-suppressive signals from the SLDGABA neurons may determine the changes in arousal states. In healthy mice (orexin+/+), the wake-promoting signal mediated by the LHOX neurons predominates over the wake-suppressive signal mediated by the SLDGABA neurons, generating a stable wakefulness. Conversely, in narcoleptic mice (orexin−/−), orexin-mediated wake-promoting signals are absent, allowing the SLDGABA neurons to produce a disproportionately strong suppression of wakefulness, resulting in wake instability seen as sleep attacks.

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Heinrich Gompf @hgompf.bsky.social · 03/07/2026

Ugh. The nylon replacements from Weber didn't work so I bought one of these. Not giving it back, this one works and I pay attention after cleaning to make sure there are no bristles on the grilling surfaces. Ridiculous: millions of these sold and like 3 people had someone incompetent use the grill.

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Heinrich Gompf @hgompf.bsky.social · 20/06/2026

Also, right around now we can't increase releases, only decrease from here on out. Buh bye futures price charade.

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Heinrich Gompf @hgompf.bsky.social · 20/06/2026

The war as defined by us (US & Israel): after the initial strikes, the US does the heavy bombing of Iran and, as the US proxy in the region, Israel fights Iran's proxy. By definition, therefore, a ceasefire includes a ceasefire between proxies. That don't make them saints, just realists.

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Christophe 🔬 Leterrier @christlet.bsky.social · 20/06/2026

Nature is healing at the reflection pool I see

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Luke Ontario @coolhand.bsky.social · 12/06/2026

When I’m fully dissociated and I forget to put on my active listening face

A photo of a sea lion holding its head up in a way that makes it look like a bug eyed person with wild air and a frowny facd

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c0nc0rdance @c0nc0rdance.bsky.social · 10/06/2026

The US capital was probably named for PIGEONS. 😲🐦 I'll explain & dive into some etymology. "Pigeon" is from Old French 'pijon', which is from Late Latin: 'pīpiō', an onomatopoeic term for a young chirping bird. The Latin version of "a peep-peep." But Romans had a /different/ name for pigeons.

static.klipy.com

Baby Bird Screaming for Food - Funny Meme

Alt: Baby Bird Screaming for Food, mouth wide open, in a nest made of straw or twigs.

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Heinrich Gompf @hgompf.bsky.social · 03/06/2026

Most mornings, he reads the note that he wrote himself reminding him to go to the doctor and decides that today is the day...

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Heinrich Gompf @hgompf.bsky.social · 01/06/2026

And that's not even including the pivot to blockchain.

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Heinrich Gompf @hgompf.bsky.social · 28/05/2026

It's all really simple. Just divert all LAX, SFO, SAN, LAS (and to a lesser extent SMF, RNO, PSP, etc.) international arrivals to Sky Harbor and SLC and then make them rent cars to get to their final destinations!

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Heinrich Gompf @hgompf.bsky.social · 30/04/2026

Was curious about the same thing. At the end of the video on the site DR posted, they talk about how the next phase is installing retractable panels. That should help the main concrete canals, but maybe still not be enough for branch canals. Maybe those smaller ones wouldn't generate enough anyway.

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Heinrich Gompf @hgompf.bsky.social · 24/04/2026

We (Anaclet + Fuller) already have two this summer so we're completely booked, if Davis is on anyone's radar...it's a bit more work, but so far the process has been OK.

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Heinrich Gompf @hgompf.bsky.social · 13/04/2026

To follow up on this, I've gotten to an age / point in my career where I often look back and am in awe at how far we've progressed. I used to do single-unit recordings of the LC 20+ years ago. Back then, we used to imagine these figures from the little we knew. Brilliant and impressive.

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Jeremiah Cohen @jeremiahycohen.bsky.social · 13/04/2026

Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1

biorxiv.org

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Heinrich Gompf @hgompf.bsky.social · 03/04/2026

Press TV also shows some good ones every so often, but they're more for a general audience (themes of solidarity, sacrifice, etc.) and not quite as hard-hitting as this.

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Heinrich Gompf @hgompf.bsky.social · 12/03/2026

It’s 75 here. Probably more humidity there?

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Heinrich Gompf @hgompf.bsky.social · 12/03/2026

How hot is it in Maryland right now? The guy seems to be sweating like crazy. About the same temp here. I’m planting things and spreading compost in the sun and I’m not sweating the way he is.

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Heinrich Gompf @hgompf.bsky.social · 11/03/2026

A direct hit on our two National Clonal Germplasm Repositories would be devastating. Big, if true.

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Heinrich Gompf @hgompf.bsky.social · 09/03/2026

Not sure if we can rename it "The American Gulf" after "Gulf of America" is already taken.

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Jonathan Eisen @phylogenomics.bsky.social · 09/03/2026

I cannot stop thinking of all the amazing and wonderful people I have known from Israel, Iran, Lebanon and other countries caught up in this war. It is people just like them who are being killed and harmed here.

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Heinrich Gompf @hgompf.bsky.social · 08/03/2026

Californians are incorrigible. What stage between "parking" or "the character of the neighborhood" and "we don't need more housing, we need affordable housing!" is "TRAFFIC!!!" at in the kill-development at any cost scale?

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Dr. Becca @docbecca.bsky.social · 08/03/2026

An utterly bleak picture of the future of academic science in America

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Heinrich Gompf @hgompf.bsky.social · 07/03/2026

I’m sure there’s a sizable population of folks with late stage Huntington’s who ride motorcycles and present at the ER with TBI needing surgery who could be used as controls… /s Sounds like the treatment didn’t work.

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Edward Nirenberg @enirenberg.bsky.social · 07/03/2026

I am just now catching up on the fact that the FDA was demanding Uniqure do sham brain surgeries (from what I can tell, comprising simulated burr holes and 10-12 hours of anesthesia) in their placebo arm for their Huntington's therapeutic, and I'm absolutely floored that this was a serious demand.

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Michael Herf @mherf.bsky.social · 05/03/2026

"Lunar gravity predicts sleep timing" - bookmarking this lunar rhythms & sleep paper as interesting. It uses a 30-day rhythm but not the 28-day declination rhythm - a claim of "gravity" should probably use the 28-day one, but I think "phase" should follow 30? europepmc.org/article/med/...

europepmc.org

Europe PMCEurope PMC

Europe PMC is an archive of life sciences journal literature.

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