iiinova — where your digital self keeps evolving

Reposted by Amro Hamdoun

Alexandre Paix @alexandrepaix83.bsky.social · 09/07/2026

What is one of the differences between an interesting non-mainstream model and a model with huge potential? Genetic tools and microscopy. Great work from the Amro Hamdoun lab, and first author Yoon Lee. Glad to have modestly contributed.

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Amro Hamdoun @hamdounlab.bsky.social · 08/07/2026

Thanks Remi and great to hear from you! Hope all is well in Villefranche. Let us know when you're ready for pictus! nsurc.ucsd.edu

nsurc.ucsd.edu

National Sea Urchin Resource Center (NSURC) at UC San Diego – Accelerating sea urchin genetics for biomedical discovery

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Amro Hamdoun @hamdounlab.bsky.social · 08/07/2026

Thanks, Nat! All credit goes to Yoon and the co-authors - they did an amazing job getting these lines through and figuring out what does (and doesn't) work.

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Amro Hamdoun @hamdounlab.bsky.social · 07/07/2026

More than a decade since CRISPR-Cas9 knock in came on the scene, it's remained underutilized in emerging models. Using transposase, and a split-FP system, we built an optimized knock in system for use in the genetically-enabled urchin, Lytechinus pictus. bit.ly/4wswLsd

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Amro Hamdoun @hamdounlab.bsky.social · 02/08/2025

I just learned a lab appropriate alternative to rock, paper, scissors- Kelp, Urchin, Rock. Kelp covers the rock, urchin eats the kelp, rock squashes the urchin!

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Reposted by Amro Hamdoun

allen institute @alleninstitute.org · 25/04/2025

Happy #FluorescenceFriday! Today we're celebrating a crowd-favorite - Lamin B1! This cell line and plasmid illuminates the nuclear envelope. Our entire Allen Cell Collection is available for just the cost of shipping from @coriellinstitute.bsky.social and @addgene.bsky.social. #CellLineOfTheWeek

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Amro Hamdoun @hamdounlab.bsky.social · 26/04/2025

Is it just me or does everyone’s lab look at them like they sprouted a third eye every time they invoke Maniatis in the lab? I swear that we isolated good nucleic acids in the 90s and we didn’t have Reddit.

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Reposted by Amro Hamdoun

allen institute @alleninstitute.org · 14/04/2025

“If you have a broken radio and you have the circuit diagram, you’ll be in a better position to fix it.” - Nuno da Costa Thank you @b0yle.bsky.social for sharing our publication of the most complete map yet of the brain's wiring and activity in @geekwire.com! 🧠📈 www.geekwire.com/2025/brain-m...

geekwire.com

Scientists unveil new wiring diagram tracing millions of connections in a bit of brain tissue

Researchers say they have mapped more than 200,000 cells in a cubic millimeter of brain tissue and have traced how they're all connected.

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Amro Hamdoun @hamdounlab.bsky.social · 10/04/2025

Wow, so that still exists?! Awesome! I remember our lab having a good run because one of the members was a former member of the Yugoslavian national basketball team.

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Reposted by Amro Hamdoun

allen institute @alleninstitute.org · 04/04/2025

Have you used our datasets, atlases, protocols, cell lines, and other #OpenScience resources in your research or classroom? Tell us about it! Share your story with us at bit.ly/opensciences... Select stories will be shared on our social media channels during #OpenScienceWeek.

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Reposted by Amro Hamdoun

Development @dev-journal.bsky.social · 31/03/2025

Distinct requirements for PI3K isoforms p110α and p110δ for PIP3 synthesis in mouse oocytes and early embryos Read this Research Article by Anne Bourdais, Guillaume Halet and colleagues: doi.org/10.1242/dev.... 🎥KitL activates oocyte PI3K

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Amro Hamdoun @hamdounlab.bsky.social · 28/03/2025

Nice work! Can’t wait to hear about this next week at DBSUMI.

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Reposted by Amro Hamdoun

Crystal Rogers, PhD @rogerslabucd.bsky.social · 28/03/2025

This paper is now published at @diffjournal.bsky.social! Congratulations to all the hardworking students who made it happen! Shout out to authors 1 & 2! MJ is our “axolotl whisperer” and Raneesh is our computational wizard- both DVM/PhD students @ucdavisvetmed.bsky.social! 💫 doi.org/10.1016/j.di...

sciencedirect.com

NSAID-mediated cyclooxygenase inhibition disrupts ectodermal derivative formation in axolotl embryos

Embryonic exposures to non-steroidal anti-inflammatory drugs (NSAIDs) have been linked to preterm birth, neural tube closure defects, abnormal enteric…

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Reposted by Amro Hamdoun

allen institute @alleninstitute.org · 26/03/2025

NOW HIRING - @adc-neuroenv.bsky.social is seeking a postdoc researcher to develop and optimize genetically encoded fluorescent and bioluminescent sensors tailored for marine model organisms. Please repost and share to your networks! 🔗 www.adc-nice.org/postdoctoral... @nathanshaner.bsky.social

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Amro Hamdoun @hamdounlab.bsky.social · 26/03/2025

Oops! Thank you for catching that…

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Amro Hamdoun @hamdounlab.bsky.social · 25/03/2025

Using wild animals for lab research has never seemed like a good idea to me.

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Amro Hamdoun @hamdounlab.bsky.social · 25/03/2025

101 L. pictus genes! 32hours. drive.google.com/drive/folder...

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Amro Hamdoun @hamdounlab.bsky.social · 25/03/2025

And... it's live! In situ hybridization has been foundational for sea urchin developmental biology. Here we report a fully automated method to probe more than a hundred genes using a general purpose liquid handler.https://www.biorxiv.org/content/10.1101/2025.03.23.644641v1

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Amro Hamdoun @hamdounlab.bsky.social · 25/03/2025

The "superpower" of sea urchins is the fact that a single female can produce millions of embryos. In the next day or so we will share a new method to analyze gene expression methods in these embryos using a fully automated, open platform.

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Reposted by Amro Hamdoun

Michael Eisen @mbeisen.bsky.social · 17/03/2025

A paywalled article from @nature.com bemoaning the exploitation of scientists' unpaid labour. Chef's kiss. Perfection. No notes.

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