Desmin is the major intermediate filament protein of muscle, yet its potential nuclear functions remain poorly understood. Here, we investigated the nuclear localization and organization of endogenous...

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The biannual Nuclear Envelope and Chromatin Organisation meeting returns for its 11th edition, following the success of the 2024 meeting.

The Francis Crick Institute’s expert scientists on how AI can help the healthcare industry

The Talk of the Town series continues at the Coffee House with author Nicholas Fox Weber discussing his new book on artist, Anni Albers.

Overlooked opportunities can help turn academic research into socioeconomic impact across Europe

The actin-related protein 2/3 (Arp2/3) complex is a central nucleator of branched actin filaments, essential for numerous cellular processes. Using superresolution imaging, we demonstrate that Arp2/3 ...

A network of plasma membrane invaginations called t-tubules plays an essential role in controlling calcium release from the endoplasmic reticulum at the triads during muscle contraction. Although the ...

Through analysis of developing chick embryos and in vitro differentiation of embryonic stem cells, a study develops a method to generate a model of the human trunk with a notochord.