11th Edition Theme: Targeting Immune Aging | Time: 9:00am-1.15pm NYC; 14:00-18.15h Paris; 10:00am-2.15pm Sao Paulo

The request comes amid continuing uncertainty over federal funding, with research and thousands of jobs on the line.

Nature - Independent mechanisms of inflammation and myeloid bias in VEXAS syndrome

Nature - Independent mechanisms of inflammation and myeloid bias in VEXAS syndrome

Nature - Independent mechanisms of inflammation and myeloid bias in VEXAS syndrome

DNA G-quadruplexes (G4s) are non–B-form DNA secondary structures that threaten genome stability by impeding DNA replication. To elucidate how G4s induce replication fork arrest, we characterized fork ...

NK cells possess innate and adaptive features, but unlike T and B cells, NK cells are not thought to require priming in lymphoid organs. Mujal et al. demonstrate that the spleen supports enhanced expa...

Transposable element exonization can yield functional protein isoforms as seen for primate-specific IFNAR2.

The CCR4-NOT complex is a major regulator of eukaryotic messenger RNA (mRNA) stability. Slow decoding during translation promotes association of CCR4-NOT with ribosomes, accelerating mRNA degradation....