iiinova — where your digital self keeps evolving

Jérôme Lecoq

@jeromelecoq.bsky.social

274 followers 19 following 190 posts

Associate Investigator at @alleninstitute.org | Building OpenScope | Systems neuroscience, large-scale neurophysiology & open science. jeromelecoq.com

Posts Replies Media

Jérôme Lecoq @jeromelecoq.bsky.social · 18/09/2026

Just like that: doi.org/10.48324/dan... : 1.2 TB of data on inhibitory neurons responses to random-dot motions in mice, shared with the world. OpenScope continues to deliver, step by step.

Jérôme Lecoq @jeromelecoq.bsky.social · 14/09/2026

Next Tuesday 9AM PST, as part of our community project on predictive processing, we plan to meet to discuss receptive fields and other analysis. All are welcome to join : allenneuraldynamics.github.io/openscope-co...

allenneuraldynamics.github.io

2026-09-15 - OpenScope Community Predictive Processing

Jérôme Lecoq @jeromelecoq.bsky.social · 10/09/2026

We will build brain observatories for the community. Step by step. How else can we hope to understand the most complex structure in the known universe? There is so much at stake.

Reposted by Jérôme Lecoq

Alex Kwan @alexkwan.bsky.social · 31/08/2026

Two large-scale electrophysiologyical studies of psilocybin's effects in mice, from @alleninstitute.org @torbenott.bsky.social and others. Should be a treasure trove of data for those interested in perceptual effects of #psychedelics www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...

Reposted by Jérôme Lecoq

Torben Ott @torbenottlab.org · 02/09/2026

#Psilocybin🍄 shifts visual cortex dynamics towards a state of surprise! Thrilled to share our work w/ OpenScope at @alleninstitute.org lead by postdoc @roberto-defilippo.bsky.social. We combined visual change detection w/ Neuropixels recordings in mice to uncover how psilocybin changes circuits 1/

Reposted by Jérôme Lecoq

Torben Ott @torbenottlab.org · 02/09/2026

5/ Our findings point to a previously unrecognized role for SST interneurons in the acute psychedelic state, potentially linking altered surprise signals to visual distortions. A huge thank-you to the entire OpenScope team, especially @jeromelecoq.bsky.social, for making this work possible!

Jérôme Lecoq @jeromelecoq.bsky.social · 31/08/2026

Tomorrow, at 9AM PST, we will continue our round-table discussion around analysis for the OpenScope Community project. Here is our meeting agenda page: allenneuraldynamics.github.io/openscope-co... Please post any material you want us to discuss on the linked forum page. Open to all!

allenneuraldynamics.github.io

2026-09-01 - OpenScope Community Predictive Processing

000

Jérôme Lecoq @jeromelecoq.bsky.social · 24/08/2026

Next Tuesday, we will meet again to discuss analysis for the predictive processing data release manuscript. To allow all in the growing group to contribute, we ask that you share 2 slides of analysis prior to the meeting. Details here : allenneuraldynamics.github.io/openscope-co... Open to all!

allenneuraldynamics.github.io

2026-08-25 - OpenScope Community Predictive Processing

000

Jérôme Lecoq @jeromelecoq.bsky.social · 18/08/2026

Tomorrow, at 9am PST, we will have another round of discussion around analysis for the data release. Agenda: allenneuraldynamics.github.io/openscope-co... Open to all!

allenneuraldynamics.github.io

2026-08-18 - OpenScope Community Predictive Processing

000

Jérôme Lecoq @jeromelecoq.bsky.social · 12/08/2026

Israel, England, Germany, US and many other countries responded to the call this morning. Neuroscience, world-wide, without borders. Recording: www.youtube.com/watch?v=66gg...

Predictive Processing Community Project weekly meeting - 08/11/2026

YouTube video by OpenScope - Allen Institute for Neural Dynamics

Jérôme Lecoq @jeromelecoq.bsky.social · 11/08/2026

As planned, tomorrow at 9AM PST, we will have a round table discussion on our data release manuscript figures. See here for meeting link and agenda. allenneuraldynamics.github.io/openscope-co... Open to all.

allenneuraldynamics.github.io

2026-08-11 - OpenScope Community Predictive Processing

000

Jérôme Lecoq @jeromelecoq.bsky.social · 08/08/2026

I just pushed a new release of allenneuraldynamics.github.io/AuthorshipEx... . This should improve the look of the collaboration view when transitioning to larger list of authors.

allenneuraldynamics.github.io

Making contributions visible: An interactive authorship viewer for team science - Interactive Authorship Viewer

A multi-dimensional authorship framework that allows readers to explore contributions along multiple axes simultaneously.

000

Jérôme Lecoq @jeromelecoq.bsky.social · 31/07/2026

Next week at our weekly 9AM PST Tuesday meeting, we will introduce a migration of our data release paper to Myst. Try out the draft demo: allenneuraldynamics.github.io/openscope_p3... Meeting open to all : allenneuraldynamics.github.io/openscope-co...

allenneuraldynamics.github.io

OpenScope Predictive Processing Community Project - Data Release - OpenScope Predictive Processing Community Project - Data Release

Jérôme Lecoq @jeromelecoq.bsky.social · 27/07/2026

OpenScope is an open platform for community-designed, high-throughput neurophysiology. Researchers propose questions; our team runs standardized experiments and releases the resulting data openly. Learn more: www.allenneuraldynamics.org/projects/ope...

allenneuraldynamics.org

OpenScope | Allen Institute for Neural Dynamics

OpenScope provides access to cutting-edge neurophysiological methods to scientists across the world. Similar to astronomical observatories, scientists propose experiments that are then executed at the...

Jérôme Lecoq @jeromelecoq.bsky.social · 06/07/2026

What I learned using Claude Science and more complex AI agentic workflows in Science. www.linkedin.com/pulse/comput...

Computational Reviews: building AI agentic workflows that doubt

The need for long-form scientific reviews Long-form reviews are some of the most useful documents in science. Every review I have contributed to has considerably helped me connect disparate pieces of ...

Jérôme Lecoq @jeromelecoq.bsky.social · 16/06/2026

Our weekly meeting recording with some "off the press" analysis of Zebra movies by Marcel Raabe. www.youtube.com/watch?v=nA3y... Lots of receptive fields in our Neuropixels data!

Predictive Processing Community Project Weekly Meeting - 6/16/2026

YouTube video by OpenScope - Allen Institute for Neural Dynamics

000

Jérôme Lecoq @jeromelecoq.bsky.social · 02/06/2026

Tomorrow, our 9AM PST session for the OpenScope predictive processing community project will be dedicated to the analysis of mesoscope two photon data. Nicholas Rodriguez will present some of his latest analysis. allenneuraldynamics.github.io/openscope-co... Open to all!

allenneuraldynamics.github.io

2026-06-02 - OpenScope Community Predictive Processing

000

Jérôme Lecoq @jeromelecoq.bsky.social · 01/06/2026

Have you ever been in an authorship conflict on an academic paper? You're not alone. This thread is for you.

Jérôme Lecoq @jeromelecoq.bsky.social · 18/05/2026

Tomorrow (9AM PST) at the weekly OpenScope predictive processing meeting, we will have a presentation on synaptic imaging pilot data analysis. As usual details are available here : allenneuraldynamics.github.io/openscope-co... Open to all!

allenneuraldynamics.github.io

2026-05-19 - OpenScope Community Predictive Processing

Jérôme Lecoq @jeromelecoq.bsky.social · 11/05/2026

Tomorrow, usual 9AM PST meeting for the OpenScope predictive processing project: allenneuraldynamics.github.io/openscope-co... Discussion on the quantification of the mesoscope region of interests (ROI) for the data release paper. Open to all!

allenneuraldynamics.github.io

2026-05-12 - OpenScope Community Predictive Processing

100

Jérôme Lecoq @jeromelecoq.bsky.social · 24/04/2026

As promised, the OpenScope predictive processing community data keeps pouring in. 2 weeks ago, it was the raw data (all files). This week: 40 complete NWBs for our Neuropixels ecephys. 45 complete NWBs Mesoscope sessions. github.com/AllenNeuralD... More is coming.

AllenNeuralDynamics openscope-community-predictive-processing · Discussions

Explore the GitHub Discussions forum for AllenNeuralDynamics openscope-community-predictive-processing. Discuss code, ask questions & collaborate with the developer community.

Jérôme Lecoq @jeromelecoq.bsky.social · 21/04/2026

Tomorrow, April 21 9AM PST, for our weekly predictive processing meeting, we will discuss coordination of data analysis for the data release paper. Meeting page: allenneuraldynamics.github.io/openscope-co... Open to all.

allenneuraldynamics.github.io

2026-04-21 - OpenScope Community Predictive Processing

Jérôme Lecoq @jeromelecoq.bsky.social · 15/04/2026

Exactly one year after sharing this gigantic review arxiv.org/abs/2504.09614, we just shared 56TB of data with the world: Entirely new experiments described in the review. And more is coming...

Neural mechanisms of predictive processing: a collaborative community experiment through the OpenScope program

This review synthesizes advances in predictive processing within the sensory cortex. Predictive processing theorizes that the brain continuously predicts sensory inputs, refining neuronal responses by...

Jérôme Lecoq @jeromelecoq.bsky.social · 13/04/2026

Tomorrow, 9AM PST, at our OpenScope community project meeting on predictive processing, Carter Peene will provide an in-depth introduction to our currently available datasets on S3 Meeting invite and agenda : allenneuraldynamics.github.io/openscope-co... Open to all!

allenneuraldynamics.github.io

2026-04-14 - OpenScope Community Predictive Processing

Jérôme Lecoq @jeromelecoq.bsky.social · 03/04/2026

Next Tuesday April 7th 9AM PST, at our community meeting on predictive processing, Pavithra Rajeswaran, Bodhisattwa Majumder, from AI2, will introduce asta.allen.ai and its potential for AI-assisted discoveries. Open to all! allenneuraldynamics.github.io/openscope-co...

allenneuraldynamics.github.io

2026-04-07 - OpenScope Community Predictive Processing

000

Jérôme Lecoq @jeromelecoq.bsky.social · 03/04/2026

We just posted a big update of our community review on predictive processing. All figures were redone for consistency and clarity. arxiv.org/abs/2504.09614 Experiments designed and described in the review are ongoing and will be done and shared with the community by late spring.

Neural mechanisms of predictive processing: a collaborative community experiment through the OpenScope program

This review synthesizes advances in predictive processing within the sensory cortex. Predictive processing theorizes that the brain continuously predicts sensory inputs, refining neuronal responses by...

Jérôme Lecoq @jeromelecoq.bsky.social · 30/03/2026

Next Tuesday, for our predictive processing meeting at 9AM PST, we will continue shaping the data release paper. Please feel free to join to contribute. allenneuraldynamics.github.io/openscope-co... Open to all!

allenneuraldynamics.github.io

2026-03-31 - OpenScope Community Predictive Processing

000

Jérôme Lecoq @jeromelecoq.bsky.social · 23/03/2026

Tomorrow, 9AM PST, as agreed last week, we will discuss the content of the data release paper for the OpenScope predictive processing community project. As usual, our meeting agenda is here : allenneuraldynamics.github.io/openscope-co... Open to all.

allenneuraldynamics.github.io

2026-03-24 - OpenScope Community Predictive Processing

100

Jérôme Lecoq @jeromelecoq.bsky.social · 16/03/2026

Tomorrow at 9AM PST, as part of our weekly community meeting on predictive processing, we will discuss the analysis plan that will follow the data collection phase. As usual here is our meeting agenda along with meeting links : allenneuraldynamics.github.io/openscope-co...

OpenScope Predictive Coding Analysis Map: draft stage1 for an (interactive?) navigator for multi-session neural data analysis · AllenNeuralDynamics openscope-community-predictive-processing · Discussi...

I drafted an analysis map as a visual companion to the analysis outlines described in the preprint. The map organises the planned analyses across the experimental paradigms focusing on mismatch res...

Jérôme Lecoq @jeromelecoq.bsky.social · 03/03/2026

Tomorrow, at 8AM PST, we will introduce the data release of 4 OpenScope projects that were simultaneously acquired in 2024: Psilocybin, texture discrimination, long-term memory, and motion perception. OpenScope continues to grow, step by step. Join us: docs.google.com/document/d/e...

docs.google.com

2026_openscope_data_release_webinar

000

Jérôme Lecoq @jeromelecoq.bsky.social · 01/03/2026

Next week, on March 4th starting at 8AM PST, we will host our annual OpenScope data release webinar. 4 OpenScope projects on psilocybin, texture discrimination, long-term visual memory, and motion perception in mice! You can find the program here : docs.google.com/document/d/e...

docs.google.com

2026_openscope_data_release_webinar

100

Jérôme Lecoq @jeromelecoq.bsky.social · 24/02/2026

Tomorrow, 9AM PST, as part of weekly meeting for the OpenScope community project on predictive processing, we will discuss : - Quick review of updated figure 2 - Ongoing experimental sheet - Planning around shared analysis Open to all on Microsoft teams! To join: lnkd.in/gvwn-VY6

This link will take you to a page that’s not on LinkedIn

000

Jérôme Lecoq @jeromelecoq.bsky.social · 16/02/2026

Tomorrow, 9AM PST, for our regular meeting for the OpenScope community project on predictive processing, we will discuss an update to our Figure 2 on the publication on arXiv. Meeting link and agenda : allenneuraldynamics.github.io/openscope-co... Open to all!

allenneuraldynamics.github.io

2026-02-17 - OpenScope Community Predictive Processing

Jérôme Lecoq @jeromelecoq.bsky.social · 09/02/2026

Dear all, Tomorrow, Feb 10 9AM PST, we will discuss figures update for our community review. As usual, you can find our meeting agenda and links here : allenneuraldynamics.github.io/openscope-co... As well as the meeting material and discussion here : github.com/AllenNeuralD... Open to all!

allenneuraldynamics.github.io

2026-02-10 - OpenScope Community Predictive Processing

100

Jérôme Lecoq @jeromelecoq.bsky.social · 20/01/2026

My weekly appointment with the Sun.

000

Jérôme Lecoq @jeromelecoq.bsky.social · 19/01/2026

Tomorrow, at 9AM PST, as part of our regular meeting for the community project on predictive processing, John Meng will present his work on "Duet model". Open to all ! allenneuraldynamics.github.io/openscope-co...

allenneuraldynamics.github.io

2026-01-20 - OpenScope Community Predictive Processing

Jérôme Lecoq @jeromelecoq.bsky.social · 12/01/2026

Tomorrow, we will meet as usual at 9AM PST time. Our meeting agenda is here : allenneuraldynamics.github.io/openscope-co... Note that the schedule has been updated to dedicate the session to the analysis of receptive fields in pilots. The presentation from John Meng has been moved to January 20.

allenneuraldynamics.github.io

2026-01-13 - OpenScope Community Predictive Processing

000

Jérôme Lecoq @jeromelecoq.bsky.social · 08/01/2026

Here is our recording from this week OpenScope community meeting on predictive processing. www.youtube.com/watch?v=qDb-... Unfortunately, we lost the very beginning due to some technical issues. We apologize for that.

Predictive Processing Community Project - Weekly meeting 01/06/26

YouTube video by OpenScope - Allen Institute for Neural Dynamics

000

Jérôme Lecoq @jeromelecoq.bsky.social · 14/12/2025

Our week long atmospheric river ended on a Saturday in Seattle, making this view even more enjoyable.

000

Jérôme Lecoq @jeromelecoq.bsky.social · 10/12/2025

As usual, here is our meeting recording : www.youtube.com/watch?v=K7W-... Exciting session with tons of data-driven discussion led by Ali Shamsnia on weeks old Neuropixels data.

Predictive Processing Community Project - Weekly meeting 12/09/25

YouTube video by OpenScope - Allen Institute for Neural Dynamics

Jérôme Lecoq @jeromelecoq.bsky.social · 08/12/2025

Tomorrow, at 9AM PST, for our regular meeting for the OpenScope Predictive Processing community project, we will have a presentation on Neuropixels pilot data analysis led by Ali Shamsnia from Farzaneh Najafi's laboratory. Open to all: allenneuraldynamics.github.io/openscope-co...

allenneuraldynamics.github.io

2025-12-09 - OpenScope Community Predictive Processing

000

Jérôme Lecoq @jeromelecoq.bsky.social · 30/11/2025

Weekly sunset run in San Francisco !

Jérôme Lecoq @jeromelecoq.bsky.social · 26/11/2025

Here is our recording from yesterday's meeting. New Neuropixels data for all. youtu.be/Wa1XiVEbJKI. If interested, please weight in on our meeting forum page : github.com/AllenNeuralD...

Predictive Processing Community Project - Weekly meeting 11/25/2025

This is a recording of the OpenScope Community Predictive Processing weekly meeting. For more details : https://allenneuraldynamics.github.io/openscope-community-predictive-processing/

000

Jérôme Lecoq @jeromelecoq.bsky.social · 25/11/2025

Tomorrow, at our usual 9AM PST time, we will introduce some of the first entirely public Neuropixels datasets generated for the OpenScope predictive processing community project. Visual and prefrontal cortex. Open to all. To join : allenneuraldynamics.github.io/openscope-co...

allenneuraldynamics.github.io

2025-11-25 - OpenScope Community Predictive Processing

Jérôme Lecoq @jeromelecoq.bsky.social · 12/11/2025

Many thanks to Colleen Gillon and Michael Berry who helped start this important effort, among many many others. The new experimental data is now going out session by session for everyone to analyze.

Jérôme Lecoq @jeromelecoq.bsky.social · 11/11/2025

Our weekly meeting for the OpenScope Predictive Processing community project is cancelled for tomorrow. We are currently collectling datasets both on the Neuropixels and SLAP2 platform. At our next meeting, we aim to introduce those datasets to allow analysis by the community.

100

Jérôme Lecoq @jeromelecoq.bsky.social · 29/10/2025

As usual, here is the recording from our meeting this morning with presentations from Carsen Stringer and Qingqing Zhang : www.youtube.com/watch?v=vmfa...

Predictive Processing Community Project - Weekly meeting 10/28/2025

Journal Club session where Carsen Stringer and Qingqing Zhang presented their recent research published on bioRxiv: “Spatial predictive coding in visual cortical neurons”…

Jérôme Lecoq @jeromelecoq.bsky.social · 23/10/2025

For our OpenScope community project meeting next week at 9AM PST on Oct 28, Carsen Stringer and Qingqing Zhang from Janelia Research Campus will present their recent bioRxiv paper on temporal vs spatial predictions. Team link and agenda: allenneuraldynamics.github.io/openscope-co... Open to all

allenneuraldynamics.github.io

2025-10-28 - OpenScope Community Predictive Processing

Jérôme Lecoq @jeromelecoq.bsky.social · 20/10/2025

Meeting will start in 30 min. Feel free to join at : teams.microsoft.com/dl/launcher/...

teams.microsoft.com

Join conversation

000

Reposted by Jérôme Lecoq

allen institute @alleninstitute.org · 20/10/2025

Congratulations to Karel Svoboda and @jshendure.bsky.social on their election to the National Academy of Medicine (@nam.edu)! Election to the Academy is one of the highest honors in health and medicine. #NAMmtg More on their journeys to this achievement: alleninstitute.org/news/karel-s...

alleninstitute.org

Karel Svoboda and Jay Shendure elected to National Academy of Medicine

The honor recognizes leaders who have demonstrated outstanding achievement and made lasting contributions to the advancement of the medical sciences, health care, and public health