The mechanism of herpes simplex virus type 1 (HSV-1) genome replication remains not fully understood. Here, the authors find that the HSV-1 origin binding protein UL9 does not mediate DNA looping but ...

Cas9 structures explain topology sensing and off-target activation.

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Proteins SegA and SegB are important for chromosome segregation and organization in archaea of the order Sulfolobales, but mechanisms are unclear. Here, Kabli et al. uncover patterns and mechanisms th...

The Emerging Innovators Fellowship is a new 3-year fully-funded postdoctoral fellowship for scientists from Black Heritage Backgrounds.