iiinova — where your digital self keeps evolving

Eugene Kim Lab

@eugenekimlab.bsky.social

200 followers 78 following 3 posts

The Eugene Kim Lab, Max Planck Institute of Biophysics, Germany www.biophys.mpg.de/structure-dynami…

Posts Replies Media

Reposted by Eugene Kim Lab

Erin E. Cutts @eecutts.bsky.social · 04/02/2026

Thanks to all involved in the super exciting work! Happy reading! And happy to answer any questions!

011

Reposted by Eugene Kim Lab

Erin E. Cutts @eecutts.bsky.social · 04/02/2026

Furthermore, we show a new role for M18BP1 as a condensin II loop stabiliser! Condensin II alone has a short loop lifetime, but when bound by M18BP1, loops are super stable. This is due to a basic region of M18BP1 contributing to DNA binding and loop anchoring!

121

Reposted by Eugene Kim Lab

Erin E. Cutts @eecutts.bsky.social · 04/02/2026

I’m very pleased to share our work looking at what controls condensin II cell-cycle dependant activity; a great collaboration with @eugenekimlab.bsky.social, @damlatetiker.bsky.social, Kyle Muir and Kumiko Samejima www.biorxiv.org/content/10.6...

biorxiv.org

22812

Eugene Kim Lab @eugenekimlab.bsky.social · 04/02/2026

How is Condensin II activated during mitosis? 🧬 @damlatetiker.bsky.social Samejima et al. uncover how Condensin II autoinhibition is relieved by the mitotic activator M18BP1, and reveal that M18BP1 also forms a composite DNA anchor with the NCAPG2–NCAPH2 subcomplex to stabilize DNA loops in vitro.

biorxiv.org

1177

Eugene Kim Lab @eugenekimlab.bsky.social · 03/12/2024

Our work on SMC Wadjet is finally out! Congrats to all co-authors!

14511