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Freddy Boutrot

@freddyboutrot.bsky.social
345 followers 53 following 34 posts

Translational researcher in plant disease resistance @Limagrain, opinions are my own 🌽🌾🧬🔬

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Reposted by Freddy Boutrot
Isabel saur @izzysaurlab.bsky.social · 5h
Great to present a major update to our manuscript: www.biorxiv.org/content/10.6... In collaboration with @grandpahiro.bsky.social, @sara-stolze.bsky.social, Matthieu Platre & the teams of Götz Hensel & Gunther Döhlemann we demonstrate that….. (1/x)
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Pam Ronald @pcronald.bsky.social · 8h
Wow! The rice RALF7 peptide provides positional information for infection initiation for M. oryzae.
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Adam Bentham @adamrbentham.bsky.social · 30/09/2026
🚨 Please share! 🚨 I'm recruiting a fully funded 4-year Gatsby Sainsbury PhD studentship at Durham! 🌱🤖 Designing plant immune receptors from scratch, combining AI protein design with structural biology and plant immunity. If you're interested please get in touch! benthamlab.org shorturl.at/U2PdV
benthamlab.org
Bentham Lab — Durham University
Bentham Lab, Centre for Programmable Biological Matter, Durham University. Structural biology and de novo protein design applied to host-pathogen interactions, plant immunity, and neglected tropical d...
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Elwira Smakowska-Luzan @elwirasmakowska.bsky.social · 28/09/2026
Our Special Issue on receptor-ligand interactions is now online! Thanks to all the authors for sharing their knowledge and views! Huge thanks to @adsteinbrenner.bsky.social @veroglez.bsky.social and @isabelmonte.bsky.social for great collaboration: ) @theplantjournal.bsky.social for the venue!
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Prof. Keiko Torii @keikoutorii.bsky.social · 24/09/2026
I am proud to share my No-AI-assisted perspective review "Plant Peptide Hormones: Three Decades of Discovery and Emerging Paradigms" for the Centennial issue of @plantphys.bsky.social 🌱🍅. It's OA, so everyone can access! 1/ academic.oup.com/plphys/advan...
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Josie Maidment @jmaidment.bsky.social · 25/09/2026
Happy to share that our study of the interaction between the MAX effector AVR-Pia and rice HMA domain-containing proteins has been published (as the cover article!) in PLOS Pathogens. journals.plos.org/plospathogen...
journals.plos.org
Two folds, many faces: The Magnaporthe oryzae MAX effector AVR-Pia targets novel rice HMA domain-containing proteins
Author summary Blast, caused by the fungal pathogen Magnaporthe oryzae, is one of the world’s most devastating rice diseases. During infection, M. oryzae secretes a diverse set of molecules, known as ...
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Graeme Kettles @graemekettles.bsky.social · 23/09/2026
Our group's latest preprint shows TurboID can be adapted for studying extracellular elicitor-receptor interactions in plants. Hopefully useful for the apoplastic MPMI community www.biorxiv.org/content/10.6... Led by former PhD @abdelrahmanqutb.bsky.social
biorxiv.org
A TurboID-based proximity labelling method for detecting extracellular protein interactions in plants
The apoplast is a primary location for interactions between plants and invasive pathogens and is the site where many pathogen-secreted effectors are perceived by cell surface immune receptors to activ...
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Martin Pacesa @martinpacesa.bsky.social · 21/09/2026
ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/Bi...
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Maurice König @maukoe.bsky.social · 21/09/2026
Very happy to see our Zip1 work highlighted in Plant Physiology 🌽 Sequential proteolysis across compartments can shape where, when and in which form peptide signals act. Thanks to @mamoonakhan.bsky.social for the insightful highlight! academic.oup.com/plphys/artic...
academic.oup.com
A tale of 2 realms: spatial processing of the maize phytocytokine Zip1
Plants rely on sophisticated cell-to-cell communication to perceive environmental changes and coordinate appropriate responses. Among the signalling molecu
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Pam Ronald @pcronald.bsky.social · 19/09/2026
Join us: Plant and Microbe Engineering for Sustainability Receptor Kinase Signaling: Fueling Plant Resilience and Development. Check out the speaker highlights. B there or B 🔲. www.youtube.com/watch?v=hs-6...
youtube.com
Receptor Kinase Signaling Meeting Promo
YouTube video by KeystoneSymposia
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Michael Hothorn @structplantbio.bsky.social · 17/09/2026
A PPNT-motif containing effector inactivates BIN2, with interesting phenotypic consequences. Nice study by @effectomics.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
A fungal effector hijacks conserved plant GSK3-like kinases to reprogram host cell identity
Stable developmental programs normally resist reprogramming, yet pathogens can override these constraints to induce profound tissue and cellular remodeling. How microbial pathogens access conserved de...
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PlantEvolution 🌱🌾 @plantevolution.bsky.social · 14/09/2026
Please consider submitting comments on the implementation for genome edited plants in the EU. Reminder: this is not the place for general statements regarding your personal vie of #NGT. Instead, the Commission is asking for input for the development of workable rules.
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Ralph Hückelhoven @huckelhovenr.bsky.social · 12/09/2026
Wingen LU, Crosbie DB, Hu Y, et al. Towards a quantitative view of the NLR gene family evolution in the genome space. Quantitative Plant Biology. 2026;7:e17. doi.org/10.1017/qpb....
doi.org
Towards a quantitative view of the NLR gene family evolution in the genome space | Quantitative Plant Biology | Cambridge Core
Towards a quantitative view of the NLR gene family evolution in the genome space - Volume 7
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Remco Stam @rstam.bsky.social · 11/09/2026
New preprint! There have been quite a few papers about RLP and RLK receptors, but none of them have a truly reproducible annotation pipeline (including my own...)... We finally made such a pipeline and look more systematically at RLPs within tomato. www.biorxiv.org/content/10.6...
biorxiv.org
PlantLRR-PRR:A Reproducible Annotation Pipeline Reveals Contrasting Evolution of Developmental and Defense Receptor-Like Proteins in Tomato
Plants perceive external and internal signals via receptors to modulate their growth, development, and defenses. Leucine-rich-repeat receptor-like-kinase (RLKs) and receptor-like-proteins (RLPs) are t...
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Michael Hothorn @structplantbio.bsky.social · 11/09/2026
Nice work by @cellsensing.bsky.social Glycan recognition by a plant damage-sensing immune receptor www.science.org/doi/10.1126/...
science.org
Glycan recognition by a plant damage-sensing immune receptor
Pathogens target and degrade the extracellular matrix surrounding plant cells. A central question is how cell wall-derived damage-associated molecular patterns (DAMPs) are recognized and integrated to...
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Nature Plants @natplants.nature.com · 08/09/2026
New Brief Communication: "Cell-based CRISPRa screen identifies a papillae-specific receptor kinase mediating broad-spectrum fungal resistance in rice" rdcu.be/ZZFv8dTuRi8a A RK that positively regulates fungal resistance via silicon-mediated physical & biochemical defences. #PlantScience
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Mariana Schuster @marischuster.bsky.social · 07/09/2026
I'm excited to share that my newly funded #ERCStG FRONTERA is recruiting two postdoctoral researchers at @ipbhalle.bsky.social 🌱🔬 If you are passionate about plant immunity, proteolysis, membrane proteins, or proteomics, I'd love to hear from you. 🧵 Please RT/share!
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PlantEvolution 🌱🌾 @plantevolution.bsky.social · 07/09/2026
Please submit comments to the EU Commission’s Call for Evidence on how to implement the new rules for "Plants obtained by new genomic techniques (#NGT)". Submission deadline 28 Sept. Below what I submitted. #plantscience ec.europa.eu/info/law/bet... ec.europa.eu/info/law/bet...
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Sophien Kamoun @kamounlab.bsky.social · 04/09/2026
Another recent addition to the team is postdoctoral researcher Erica Hawkins @scientisterica.bsky.social who joins us from the Earlham Institute to advance our venture projects in NLR bioengineering. Stay tuned for more news from NELARIX in 2027! 🌱🧬 kamounlab.tumblr.com/post/8268367...
kamounlab.tumblr.com
Kamoun Lab @ TSL
Another recent addition to the team is postdoctoral researcher Erica Hawkins, who joins us from the Earlham Institute to advance our venture projects in NLR bioengineering. Stay tuned for more news...
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Tatsuya Nobori @tatsuyanobori.bsky.social · 03/09/2026
Great work by Ingram & Zipfel labs. Congratulations, everyone! An embryo-derived peptide signal directs endosperm polarity in Arabidopsis www.science.org/doi/10.1126/...
science.org
An embryo-derived peptide signal directs endosperm polarity in Arabidopsis
Angiosperm seed formation requires the coordinated development of the products of double fertilization—the embryo and the endosperm. The endosperm mediates efficient nutrient transfer from surrounding...
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Daniel Croll @danielcroll.bsky.social · 04/09/2026
Our lab is looking for PhD students to join us in 2027 🎓🎉 The projects can be structured around our research directions: - Transposable element dynamics - Fungal pangenomics - ML/language model genomics applications - Pathogen adaptation More here pathogen-genomics.org ("Jobs") and please share! 🙏
pathogen-genomics.org
Evolutionary genomics of pathogens
Croll lab at University of Neuchatel. The lab of Daniel Croll wants to understand how pathogens evolve to cause disease. For this, we mainly focus on major crop pathogens to unravel mechanisms of rapi...
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Nature Plants @natplants.nature.com · 02/09/2026
New News & Views: "Plant immune receptors built in silico and evolved in vivo" rdcu.be/Kh9wTHbDrKva Protein design & directed evolution in planta to build synthetic immune receptors that detect diverse pathogen proteins: on-demand design and refinement of resistance genes.
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Tatsuya Nobori @tatsuyanobori.bsky.social · 03/09/2026
Excited to launch our ERC project ImmuneCellState 🚀 We’ll investigate how individual plant cells respond to pathogens and explore new dimensions of plant immunity research by integrating single-cell/spatial omics, deep learning and genome editing. @thesainsburylab.bsky.social @erc.europa.eu
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Juan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 03/09/2026
Super excited of obtaining a ERCstg to support our project MORPHEUS 🎉🎉 Receiving this grant is a pivotal moment for my lab at @zmbp-tuebingen.bsky.social as will allow to extend the scope of our research in cellular reprogramming using ribosome dormancy as entry point 😴🌱❄️🔬 @erc.europa.eu
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IPB Halle @ipbhalle.bsky.social · 03/09/2026
Our junior research group leader, Mariana Schuster, has been awarded the ERC Starting Grant, which comes with a grant of 1.5 million euros. Congratulations @marischuster.bsky.social! #ERCStg @erc.europa.eu More Information: www.ipb-halle.de/en/article/e...
ipb-halle.de
ERC Starting Grant: 1.5 Million Euros for Excellent Research on Plant Immunity
IPB Press Release, September 3, 2026 A great success for plant research at the Leibniz Institute of Plant Biochemistry (IPB) in Halle: The independent junior research group leader Mariana Schuster has been awarded a highly funded ERC Starting Grant from the European Research Council for her FRONTERA project. Over a period of five years and with funding of 1.5 million euros, she and her team will investigate how the targeted cleavage of membrane proteins regulates the immune defense of plants.
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Laura Medina-Puche @lauramepul.bsky.social · 31/08/2026
🌱 Job alert! A PhD position starting in 2027 is available with me and Andrea Gust @zmbp-tuebingen.bsky.social as part of the Cluster of Excellence @greenrobust.de 👉 Interested? Apply now &/or share! uni-tuebingen.de/universitaet... #PlantSciJob #PhDPosition
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Remco Stam @rstam.bsky.social · 30/08/2026
New preprint online! We sequenced several hundred Zymoseptoria isolates from different fields through a field epidemic to ask what really drives short-term evolution. Fungicide selection or seasonal epidemic progression? www.biorxiv.org/content/10.6...
biorxiv.org
Standing genetic variation buffers field populations of Zymoseptoria tritici against seasonal and fungicide selection
### Competing Interest Statement AT was funded by BASF under a formal scientific collaboration agreement. BASF did not exert control over the data collection, analysis, or interpretation of results. ...
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Peter Moffett @moffettpeter.bsky.social · 26/08/2026
New preprint. Effector-driven extracellular niche establishment (EDEN) involves water-soaking. We asked if apoplastic water accumulation has an effect on the plant immune response. @charlesrleveillee.bsky.social @s-gauthier.bsky.social @ilafores.bsky.social y.social www.biorxiv.org/content/10.6...
biorxiv.org
Atypical immunity induced by extracellular water in plants
Microbial pathogens require nutrients and water to support their growth and proliferation. Pathogen-mediated resource acquisition is orchestrated by the secretion of virulence factors that have evolve...
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Edel Pérez-López 🇨🇦 @edelplopez.bsky.social · 26/08/2026
So happy to see this officially published in its final form! 🎉📄 Beautiful work, Melaine González García! 👏🤩 @mpmijournal.bsky.social 🔗 : apsjournals.apsnet.org/doi/10.1094/...
apsjournals.apsnet.org
A Clubroot Pathogen PBS3-Like Effector Manipulates Hormonal Crosstalk to Alter Root Morphology in Arabidopsis and Canola | Molecular Plant-Microbe Interactions
Plasmodiophora brassicae, the causal agent of clubroot disease, actively manipulates host hormone pathways to promote infection. Previous studies identified PbGH3 as a putative GH3-like effector with ...
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Dan Garisto @dangaristo.bsky.social · 25/08/2026
In May it was big news when 100+ suspicious images were found in Thermo Fisher's catalog. Now, that number has expanded dramatically to 18,000+, thanks to some arduous searching by @reeserichardson.bsky.social. My reporting on the massive trove and its implications for antibody reliability:
nature.com
More than 18,000 questionable images found in antibody catalogues of 15 companies
Science sleuth’s findings raise questions for researchers working to improve the reliability of commercial antibodies.
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International Society for Molecular Plant-Microbe Interactions @ismpmi.bsky.social · 24/08/2026
Plant-Microbe enthusiasts! The next Road to Jeju Legends of ISMPMI series speaker is Jonathan Jones. The webinar is free to attend, but you must register: uchicago.zoom.us/webinar/regi... Attend live on September 30, 2026 3pm UTC or watch it later on the ismpmi.org.
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Sam Mugford @samtmugford.bsky.social · 12/08/2026
New pre-print from the @saskiahogenhout.bsky.social lab We (@qunliu07.bsky.social et al.) show that the aphid effector protein CathB6, in addition to suppressing plant immunity via EDS1, also alters the regulation of chloroplast-nuclear signalling to maintain photosynthetic gene expression. 1/n
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Gitta Coaker @gittacoaker.bsky.social · 12/08/2026
nlp receptor identified in lettuce, different from the receptor in brassicas; convergent evolution in different plant families. www.pnas.org/doi/10.1073/...
pnas.org
A lettuce receptor-like kinase recognizes the highly conserved heptapeptide motif within microbial Nep1-like proteins | PNAS
Plants rely on cell surface immune receptors to detect microbial patterns and initiate effective defense responses. Although the Asteraceae family ...
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Edel Pérez-López 🇨🇦 @edelplopez.bsky.social · 16/08/2026
We are many but we are looking for 3 more PhD students! 🪲🥦🧬 The projects will explore: 🧬 Evolution of ankyrin-repeat effectors in gall-forming plasmodiophorids 🦠 Microbiome-mediated insect adaptation to extreme environments 🍃 Leafhopper effectors at the plant–insect interface Full description ⬇️
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GeminiTeamLab @geminiteamlab.bsky.social · 18/08/2026
So excited and incredibly grateful for this opportunity! 🦠🌱🧬
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bioRxiv Plant Bio @biorxiv-plants.bsky.social · 07/08/2026
A wheat immune receptor pair executes cell death through a helper MLKL www.biorxiv.org/content/10.64898/20…
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Thorsten Langner @thorstenlangner.bsky.social · 06/08/2026
🚨safe the date🚨 our SNP2Prot SFB @snp2prot.bsky.social @unihalle.bsky.social will host an international conference next summer (June 21st-23rd 2027) with a fantastic line-up of international experts. Registration opens October 17th.
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Michael Hothorn @structplantbio.bsky.social · 05/08/2026
Out in @natplants.nature.com, mapping of brassinosteroid chemical features required for (1) receptor binding, (2) ligand positioning and (3) co-receptor recruitment. Fantastic work by Alberto Caregnato & @hmchen93.bsky.social and our friends in Olomouc. Funding:@snf-fns.ch -> doi.org/10.1038/s414...
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Juan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 05/08/2026
PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens. 🌱🍄🔬 See details below 👇 #PlantSciJobs
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Molecular Plant & Plant Communications @mplantpcom.bsky.social · 26/06/2026
High-Throughput Glycan Array Screening Reveals Rhamnogalacturonan-I as a ligand for Arabidopsis Leucine-Rich Repeat Receptor Kinases Involved in Plant Immunity #research #MolecularPlant cell.com/molecular-pl...
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Freddy Boutrot @freddyboutrot.bsky.social · 03/08/2026
The C-terminal tail of Cf resistance proteins determines the intensity of the effector-triggered hypersensitive response-related cell death doi.org/10.1093/plph...
doi.org
The C-terminal tail of Cf resistance proteins determines the intensity of the effector-triggered hypersensitive response-related cell death
Abstract. Cf resistance proteins of tomato that provide resistance against the extracellular fungal pathogen Fulvia fulva are receptor-like proteins (RLPs)
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bioRxivpreprint @biorxivpreprint.bsky.social · 30/07/2026
Structural and functional insights into the role of Cysteine-Rich Receptor-Like Kinase 18 (CRK18) in Arabidopsis www.biorxiv.org/content/10.64898/20…
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Peter Solomon @plantpathpete.bsky.social · 03/08/2026
We're recruiting a Postdoctoral Fellow at ANU to help strengthen Australia's preparedness for wheat blast. The project spans plant pathology, genetics, breeding and biosecurity, with collaborators in Australia and Brazil. Apply here: tinyurl.com/25zcj9yy #PlantScience #Postdoc #Biosecurity
tinyurl.com
Postdoctoral Fellow - Canberra / ACT, ACT, Australia
Classification: Academic Level ASalary package: $91,546 - $114,906 per annum plus 17% superannuationTerm: Full-Time, Continuing (Contingent Funded) Note: This position will be primarily based at the N...
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Yasuhiro Kadota @yasukadota.bsky.social · 30/07/2026
The receptor kinase NILR1 confers nematode resistance through developmental rather than canonical immune signaling www.biorxiv.org/content/10.6...
biorxiv.org
The receptor kinase NILR1 confers nematode resistance through developmental rather than canonical immune signaling
### Competing Interest Statement The authors have declared no competing interest.
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The EMBO Journal @embojournal.org · 30/07/2026
Role of membrane-organizing SPFH proteins in plants: @hannah-web.bsky.social, Alexandra Ehinger, @birgitkemmerling.bsky.social et al define how Arabidopsis HIR2 forms higher-order assemblies and organizes receptor signaling domains link.springer.com/article/10.1...
link.springer.com
The Arabidopsis SPFH protein HIR2 modulates receptor signaling and plasma membrane organization - The EMBO Journal
Plant plasma membrane proteins are organized into distinct domains; however, the principles that govern this spatial organization are not fully understood. HYPERSENSITIVE-INDUCED REACTION (HIR) protei...
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Nature Plants @natplants.nature.com · 24/07/2026
"Programmable design of synthetic plant immune receptors for pathogen protein recognition" www.science.org/doi/10.1126/...
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John Innes Centre @johninnescentre.bsky.social · 21/07/2026
📢 Registration now open for the UK Precision Breeding Farming Futures Conference Join us on Thursday, 24 September at the Norwich Research Park, uniting farming, science, policy, and industry to explore the fast‑moving landscape of precision breeding in the UK: www.jic.ac.uk/event/uk-pre...
UK Precision Breeding – Farming Futures Conference.  Registration now open.
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The Sainsbury Laboratory @thesainsburylab.bsky.social · 21/07/2026
Less than two weeks left to apply to this Scientist/Senior Scientist - Innovation Pilot Lead position! More info below ⬇️
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Adam Bentham @adamrbentham.bsky.social · 13/07/2026
Excited to see our new preprint on bioRxiv! 🌱🤖 We used AI protein design (RFdiffusion + ProteinMPNN) to build brand-new sensor domains from scratch and installed them in a rice NLR immune receptor engineering recognition of a Fusarium effector FoSSP17
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Volker Lipka @volkerlipka.bsky.social · 14/07/2026
We are currently recruiting an Independent Junior Research Group Leader in the field of biotic and/or abiotic stress biology in plants at the University of Göttingen (starting in January 2027). www.uni-goettingen.de/de/644546.ht... Best, Salma Balazadeh & Volker Lipka
uni-goettingen.de
Stellenanzeigen - Georg-August-Universität Göttingen
Webseiten der Georg-August-Universität Göttingen
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