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Saskia Hogenhout

@saskiahogenhout.bsky.social
1.9K followers 1.4K following 7 posts

Scientist at the John Innes Centre. Molecular Plant-Microbe-Insect Interactions. Loves travelling, reading and hiking. Location : Norwich, UK. Website: www.jic.ac.uk/people/saskia-hogenho…

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Reposted by Saskia Hogenhout
Tatsuya Nobori @tatsuyanobori.bsky.social · 15/01/2026
ECRs in plant–microbe interactions: Join us in Norwich for an intensive, interactive 1.5-week Summer Conference at TSL (20–31 July). Lots of opportunities for networking and deep discussions. (We also plan to offer hands-on practical sessions using our technologies 🔬🧬)
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Reposted by Saskia Hogenhout
John Innes Centre @johninnescentre.bsky.social · 09/01/2026
Congratulations to @saskiahogenhout.bsky.social on this fantastic appointment! 👏
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Saskia Hogenhout @saskiahogenhout.bsky.social · 16/12/2025
New preprint on pop #genomics of #spittlebug—the main insect vector of Xylella, the bacterium that has ravaged olive groves in southern Italy 🇮🇹 🫒 Take-home: problematic insect vector may be less widespread than initially thought—important implications for disease control 💥 👇
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Hassan Salem @hassansalem.bsky.social · 24/11/2025
There’ll be several opportunities to join the group, starting w/ a PhD studentship via the BBSRC-NRP Doctoral Training Partnership. Team up w/ us, @saskiahogenhout.bsky.social & @berasymbionts.bsky.social to answer how microbes shape insect behavior: biodtp.norwichresearchpark.ac.uk/projects/mic...
biodtp.norwichresearchpark.ac.uk
Microbial determinants of behaviour in herbivorous beetles (SALEM_J26DTP) | Doctoral Training Partnership
Many animals rely on beneficial microbes for nutrition, defence, or reproduction. In this project, the student will explore an exciting new dimension of these relationships:
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Saskia Hogenhout @saskiahogenhout.bsky.social · 01/11/2025
Guillaume de Nourriche! #Norwich 🇬🇧
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Reposted by Saskia Hogenhout
Matteo Gravino @matteogravino.bsky.social · 01/08/2025
🎉Thrilled to share our latest work, now published in @newphyt.bsky.social! 🧑‍🔬 @matteogravino.bsky.social, @samtmugford.bsky.social, @saskiahogenhout.bsky.social et al., @johninnescentre.bsky.social #️⃣ #PlantScience #PlantImmunity 📄 Read the full paper👇 nph.onlinelibrary.wiley.com/share/8QSRJ9...
Model: Activation and suppression of defences in plant–aphid interactions. Upper left panel: aphid stylet penetration of the cell wall releases oligogalacturonides (OGs), which induce PAMP/DAMP-triggered immunity (PTI/DTI) in a process dependent on BRASSINOSTEROID INSENSITIVE 1-ASSOCIATED RECEPTOR KINASE 1 (BAK1), ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1), and CPK5/6/11 (data herein). The stabilisation of pattern recognition receptors (PRRs) and coreceptors at the plasma membrane may rely on the deubiquitination (DUB) activity of ASSOCIATED MOLECULE WITH THE SH3 DOMAIN OF STAM (AMSHs; Gravino et al., 2024). Upper right panel: the Mp10 effector, introduced by aphids into the cell cytoplasm (Mugford et al., 2016), suppresses OG-induced reactive oxygen species (ROS) (data herein) and flg22-induced PTI (Bos et al., 2010). Mp10 targeting of plant AMSHs is implicated in these processes (Gravino et al., 2024). EDS1 is essential for Mp10-mediated ROS suppression and PRR destabilisation (data herein), acting through an unidentified mechanism (denoted by the double-sided arrow with an asterisk). Lower left panel: effector-triggered immunity (ETI) is activated through EDS1, either directly or indirectly, upon recognition of Mp10 and/or its activities by a TNL (Gravino et al., 2024; Rao et al., 2024). Salicylic acid glucosyltransferase 1 (SGT1) is also required for TNL/ETI activation (Bos et al., 2010). Lower right panel: aphids secrete additional effectors, such as cathepsin B proteins (e.g. CathB6), which target EDS1 to suppress ETI (Liu et al., 2025). Solid arrows, increased activation; solid blunt-ended arrows, increased suppression; Dashed arrows, reduced activation; Dashed -blunt-ended arrows, reduced suppression.
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Qun Liu @qunliu07.bsky.social · 17/07/2025
Our paper is now online in Science Advances! Congrats @saskiahogenhout.bsky.social @johninnescentre.bsky.social and all coauthors! www.science.org/doi/10.1126/...
science.org
Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies
Aphids hijack plant immunity via p-bodies, but plants fight back with a heat shock protein in an unexpected twist on defense.
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Reposted by Saskia Hogenhout
Sam Mugford @samtmugford.bsky.social · 16/07/2025
Aphid Saliva fans, happy news, this amazing story is now out in Science Advances www.science.org/doi/10.1126/... congrats @qunliu07.bsky.social @saskiahogenhout.bsky.social et al @johninnescentre.bsky.social 24h after a triumphant presentation at #ismpmi2025
science.org
Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies
Aphids hijack plant immunity via p-bodies, but plants fight back with a heat shock protein in an unexpected twist on defense.
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Saskia Hogenhout @saskiahogenhout.bsky.social · 16/07/2025
www.science.org/doi/10.1126/...
science.org
Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies
Aphids hijack plant immunity via p-bodies, but plants fight back with a heat shock protein in an unexpected twist on defense.
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Saskia Hogenhout @saskiahogenhout.bsky.social · 16/07/2025
www.biorxiv.org/content/10.1...
biorxiv.org
Effector Innovation in Genome-Reduced Phytoplasmas and Other Host-Dependent Mollicutes
Obligate host-associated bacteria with reduced genomes, such as phytoplasmas, face strong evolutionary constraints, including metabolic dependence on hosts, limited horizontal gene transfer (HGT), and...
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Reposted by Saskia Hogenhout
Sophien Kamoun @kamounlab.bsky.social · 30/06/2025
I just published: Postcard from Sardinia: a fragile migrant In an age of growing tension between north and south, one ordinary orange butterfly flutters freely across continents, unbothered by border checkpoints. This is the story of the painted lady. kamounlab.medium.com/postcard-fro...
kamounlab.medium.com
Postcard from Sardinia: a fragile migrant
In an age of growing tension between north and south, one ordinary orange butterfly flutters freely across continents, unbothered by border…
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Reposted by Saskia Hogenhout
Genome Biology and Evolution @genomebiolevol.bsky.social · 30/06/2025
Follow authors on Bluesky: @caterpillar-coevo.bsky.social @tom-mathers.bsky.social @samtmugford.bsky.social @saskiahogenhout.bsky.social @fionabugsnbees.bsky.social @tcheaven.bsky.social
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Sam Mugford @samtmugford.bsky.social · 18/03/2025
Me on the radio this morning talking about UK preparedness for #xylella, froghoppers and the BRIGIT project in the @saskiahogenhout.bsky.social lab @johninnescentre.bsky.social www.bbc.co.uk/sounds/play/...
bbc.co.uk
Farming Today - 18/03/25 - Hare coursing, xylella and soil microplastics - BBC Sounds
Farmers fear the rise in violent encounters with illegal hare coursers.
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Sam Mugford @samtmugford.bsky.social · 07/03/2025
Congrats Dr @reubenpjames.bsky.social! latest PhD from @saskiahogenhout.bsky.social lab @johninnescentre.bsky.social
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Rebecca J Hall @drrebeccajhall.bsky.social · 16/12/2024
I'm super excited to spend some time in Tracey Chapman's lab (UEA) learning all aspects of insect handling and infection. I'll then be working with @saskiahogenhout.bsky.social (JIC) on a bioinf project characterising bacterial symbionts in one of her really cool insect collections.
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Tom Heaven @tcheaven.bsky.social · 06/12/2024
@tom-mathers.bsky.social @samtmugford.bsky.social @fionabugsnbees.bsky.social @caterpillar-coevo.bsky.social
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Reposted by Saskia Hogenhout
Tom Heaven @tcheaven.bsky.social · 06/12/2024
Our preprint is now live! We have sequenced the genomes of three psyllid species. These insects pests transmit devastating plant diseases like 'zebra chip' in potatoes and 'carrot yellows' in carrots. 🥕 #MolecularEntomology #MPMI #PlantPathology #psyllids #liberibacter
hubs.ly
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Elisabeth Bik @elisabethbik.bsky.social · 02/12/2024
Anyway, it's quite an accomplishment for this Dutch microbiologist to live rent-free in the head of "the greatest microbiologist of all times" (or however he thinks of himself). He now even writes papers about me!
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Reposted by Saskia Hogenhout
Johanna Joyce @johannajoyce.bsky.social · 25/11/2024
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/
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The Tattooed Professor @schwessinger.bsky.social · 01/12/2024
Our latest contribution to understanding plant pathogenic fungi better led by UQ. Intragenomic variants of a putative effector drive early-stage infection in a broad host-range rust fungus www.biorxiv.org/content/10.1...
biorxiv.org
Intragenomic variants of a putative effector drive early-stage infection in a broad host-range rust fungus
Rust fungi are pathogens that impact plants of environmental, agricultural, cultural, and economic importance. Their mechanisms of pathogenicity are not well-understood but are likely governed by effe...
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GetGenome @getgenome.bsky.social · 27/11/2024
GetGenome Newsletter November 2024 getgenome.net/network
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Reposted by Saskia Hogenhout
Tatsuya Nobori @tatsuyanobori.bsky.social · 27/11/2024
Excited to co-organize the session 'Resolving heterogeneity in plants with imaging and omics' with @ignaciorubiosomoza.bsky.social at ICAR2025! Looking forward to having a wide range of speakers from abstracts. Stay tuned for more details! 📅 June 16-20 Ghent 🇧🇪 web.cvent.com/event/448810...
web.cvent.com
Concurrent Sessions. - International Conference on Arabidopsis Research: ICAR2025
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Beverley Glover @beverleycubg.bsky.social · 26/11/2024
My first post here! We’re looking for an enthusiastic plant developmentalist to join our team as a postdoc working on how this wonderful plant builds sexually deceptive flowers. Link here: www.jobs.cam.ac.uk/job/49334/
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Nick Desnoyer @nickdesnoyer.bsky.social · 22/11/2024
Mutations in da1, eod1, and erecta
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Sam Mugford @samtmugford.bsky.social · 21/11/2024
The @saskiahogenhout.bsky.social lab are knocking it out of the park this week, another preprint about the mechanisms of an aphid effector protein
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Reposted by Saskia Hogenhout
Qun Liu @qunliu07.bsky.social · 21/11/2024
Thanks to everyone involved in this work @qunliu07.bsky.social, Anna Neefjes, Roksolana Kobylinska, @samtmugford.bsky.social, @mmarzo.bsky.social, James Canham (@thesainsburylab.bsky.social), @marischuster.bsky.social, Renier van der Hoorn, Yazhou Chen, @saskiahogenhout.bsky.social
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Qun Liu @qunliu07.bsky.social · 21/11/2024
We're happy to present a pre-print from the Hogenhout lab (@saskiahogenhout.bsky.social), describing how a family of proteases in aphid oral secretions suppress plant immunity.
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Jay Keche G. @caterpillar-coevo.bsky.social · 19/11/2024
I'm currently a postdoc with @saskiahogenhout.bsky.social but will be starting as a Presidential Postdoctoral Fellow at Arizona State University next year with @kstsosie.bsky.social
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Sam Mugford @samtmugford.bsky.social · 18/11/2024
We’re delighted to share our latest preprint from the Hogenhout lab (@saskiahogenhout.bsky.social) on the molecular mechanisms on plant-aphid interactions. Here we show how the aphid Mp10 effector protein acts as a local anaesthetic to suppress the plant perception of aphid attack
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David Ho @davidho.bsky.social · 05/10/2024
Almost 40 years ago in 1985, Carl Sagan told Congress that continuing to burn fossil fuels will increase global temperature, cause climate change, melt glaciers and ice sheets, and cause sea level rise.
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British Society of Plant Pathology @bspp.bsky.social · 13/09/2024
Today’s parallel sessions are kicking off now, and the ‘plant colonisers manipulating plant development’ session with an inspiring talk by @saskiahogenhout.bsky.social telling us all about how stealthy microbes shape their hosts.
A female professor delivering a lecture
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Jay Keche G. @caterpillar-coevo.bsky.social · 12/07/2024
Congrats to @saskiahogenhout.bsky.social a big day and well deserved recognition for years of incredible research
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Saskia Hogenhout @saskiahogenhout.bsky.social · 11/04/2024
Super proud of my niece Marit van Wijk for winning the Jan Kommandeur Prize (biology, chemistry, physics and other #STEM subjects) for her project “Radio astronomy with a self-built radio telescope.” 🎉🥳 rug.nl/society-busine…
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Reposted by Saskia Hogenhout
GetGenome @getgenome.bsky.social · 13/12/2023
Big day for @GetGenome ! Our first in-person workshop! #GGTunisia2022 @EspaceZmorda Tunis 🇹🇳
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GetGenome @getgenome.bsky.social · 23/12/2023
What better way to end 2023 than meeting #GGTunisia2022 Alumni at the inaugural GetGenome Symposium in Tunisia! GetGenome launched in Tunisia and has been hugely inspired by its research community. More to come.
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Sophien Kamoun @kamounlab.bsky.social · 04/01/2024
The Vaccine Alliance @GAVI www.gavi.org
gavi.org
Gavi, the Vaccine Alliance
Gavi is an international organisation created in 2000 to improve access to new and underused vaccines for children living in the world's poorest countries.
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