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Houming Chen

@hmchen93.bsky.social
69 followers 135 following 8 posts

plant cell biologist / postdoc @ unige

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Reposted by Houming Chen
Michael Hothorn @structplantbio.bsky.social · 11/09/2026
Nice work by @cellsensing.bsky.social Glycan recognition by a plant damage-sensing immune receptor www.science.org/doi/10.1126/...
science.org
Glycan recognition by a plant damage-sensing immune receptor
Pathogens target and degrade the extracellular matrix surrounding plant cells. A central question is how cell wall-derived damage-associated molecular patterns (DAMPs) are recognized and integrated to...
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Reposted by Houming Chen
Margot Smit @likeyoda1.bsky.social · 24/08/2026
📣 Job alert! 2 Positions starting 2027. PhD position with me and @bayerlab.bsky.social on Robustness of embryonic and stomatal development, part of @greenrobust.de Postdoc position on the regulation of cell state, following up on some exciting snRNAseq dat! Apply now or share! #PlantSciJob
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Dolf Weijers @dolfweijers.bsky.social · 18/08/2026
It took some time, but we are thrilled to present the first major outcome of our @erc.europa.eu ERC DIRNDL AdG project: Evgeniya Pukhovaya @epukh.bsky.social and others in our team describe the discovery of a mechanism for polar protein targeting in plants (1/13) www.biorxiv.org/content/10.6...
biorxiv.org
Systematic proteomics identifies a conserved mechanism for polar targeting of plant cortical proteins
Multicellular development is tightly coupled to the polarization of individual cells, which partitions polar proteins along the cell cortex and can control asymmetric cell division, anisotropic growth...
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Plant Science Spotlight @plant-sci.bsky.social · 13/08/2026
🌱🧬ARFs are ancient DNA-binding proteins that predate auxin. Signaling evolved by linking them to a degradation-based system, adding responsiveness while keeping core function. A model for how plant networks evolve. #plantscience @newphyt.bsky.social nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com
AUXIN RESPONSE FACTORs: from transcription factors to auxin effectors
Molecular evolution of AUXIN RESPONSE FACTOR (ARF) effector function.
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Reposted by Houming Chen
Bayer lab @bayerlab.bsky.social · 11/08/2026
Our latest preprint is online. www.biorxiv.org/content/10.6... Our exciting data show that embryonic patterning in Arabidopsis is kick-started by differential sensitivity towards auxin and not by differential distribution of auxin.
biorxiv.org
Before auxin distribution matters: Prepatterning of the Arabidopsis embryo axis by MPK6-dependent AUX/IAA8 phosphorylation
In growth and development of plants, the signaling molecule auxin plays an instrumental role. Many patterning processes are controlled by auxin signaling in a self-organizing matter. After fertilizati...
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Reposted by Houming Chen
Margot Smit @likeyoda1.bsky.social · 11/08/2026
Fresh preprint online from our group! We find that stomatal maturation IS possible in the embryo, when they lack ERECTA signaling, but then still, only at the cotyledon tip. A thread. www.biorxiv.org/content/10.6...
biorxiv.org
ERECTA signaling controls the timing of Arabidopsis Guard Cell maturation at the embryonic leaf tip
While cell identities are established early during embryogenesis, these cells remain immature until germination, and the mechanisms enforcing this developmental pause are poorly understood. Embryonic ...
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Reposted by Houming Chen
Mauricio Contreras @mpcontreras.bsky.social · 31/07/2026
New in @embojournal.org from @birgitkemmerling.bsky.social's lab: HIR2 assembles into giant ring-like complexes at the plasma membrane, shaping receptor dynamics and immune signalling. Genetics + biochem + super-res imaging + AF3 modelling, all in one! Check it out👇 link.springer.com/article/10.1...
link.springer.com
The Arabidopsis SPFH protein HIR2 modulates receptor signaling and plasma membrane organization - The EMBO Journal
Plant plasma membrane proteins are organized into distinct domains; however, the principles that govern this spatial organization are not fully understood. HYPERSENSITIVE-INDUCED REACTION (HIR) protei...
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mariebarberon.bsky.social @mariebarberon.bsky.social · 21/05/2026
The RTS (Swiss TV) visited our lab and talked about our recent work on natural variation for suberin in the News yesterday evening! (In French)
rts.ch
Les racines, un espoir pour l'adaptation des plantes face aux stress climatiques - 19h30 - Play RTS
Play RTS vous permet de visionner ou d'écouter de nombreuses émissions tv ou radio, quand et aussi souvent que vous le souhaitez.
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Reposted by Houming Chen
Michael Hothorn @structplantbio.bsky.social · 21/05/2026
Team effort from @fxrico.bsky.social, Oded, Pierre, Andrea, @hmchen93.bsky.social, Larissa now out in @pnas.org The Kelch phosphatase BSU1 is a PP1-like serine/threonine phosphatase involved in cell cycle regulation, not a tyrosine phosphatase in brassinosteroid signaling 👍 doi.org/10.1073/pnas...
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Jian-Pu 韩 @jian-pu.bsky.social · 05/05/2026
It’s FINALLY out! We investigated the natural variations for endodermal suberin and identified SUBER GENE1 (SBG1)- Type One Protein Phosphatases (TOPPs) as a novel module that regulates endodermal suberization. @mariebarberon.bsky.social rdcu.be/fgU6g #PlantScience
rdcu.be
GWAS reveal SUBER GENE1-mediated suberization via type one phosphatases
Nature Plants - A genetic screen across Arabidopsis accessions identifies SBG1 as a regulator of root abscisic acid response and endodermal suberin deposition via type 1 protein phosphatases,...
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Reposted by Houming Chen
Roman Ulm @romanulm.bsky.social · 03/02/2026
New preprint out! Zhoubo Hu et al "A redox-regulated RCC1-like protein controls catalase activity in Arabidopsis". We identify CAIR1, a UVR8-interacting protein, as a redox-responsive regulator of catalase localization and activity, maintaining cellular ROS balance. 🌱 www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Houming Chen
Michael Hothorn @structplantbio.bsky.social · 07/01/2026
Our new year starts of course with new preprint on brassinosteroid signaling tinyurl.com/nhzcfkxd. We re-analyzed the function of Kelch phosphatases, which were previously characterized as protein tyrosine phosphatases that dephosphorylate the critical pTyr200 in the GSK3 kinase BIN2. (1/6)
tinyurl.com
Plant Kelch phosphatases are Ser/Thr phosphatases involved in cell cycle regulation
Brassinosteroids (BRs) are plant steroid hormones sensed at the cell surface by the membrane receptor kinase BRI1. Activation of BRI1 leads to the dephosphorylation of BZR1/BES1 transcription factors ...
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Reposted by Houming Chen
Michael Hothorn @structplantbio.bsky.social · 29/11/2025
Our latest collaboration with Fiedler lab @fmp-berlin.de and Panse labs UZH out on @biorxiv-plants.bsky.social. Using bead-adsorbed, non-hydrolyzable inositol pyrophosphate (PP-InsP) analogs, we isolated many putative PP-InsP-binding proteins from Arabidopsis. www.biorxiv.org/content/10.1... (1/6)
biorxiv.org
An inositol pyrophosphate interaction screen provides insight into the regulation of plant casein kinase II
Inositol pyrophosphates (PP-InsPs) are key nutrient messengers in plants, but their protein receptors remain poorly defined. Using a systems-level affinity screen with biotinylated InsP₆, InsP₇, and I...
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Reposted by Houming Chen
Laura Ragni @lauraragni.bsky.social · 20/11/2025
It’s finally out! 🎉 Work led by former PhD student @wei-xiao-botany.bsky.social , in collaboration with @bayerlab.bsky.social and @bertderybel.bsky.social AINTEGUMENTA phospho-switch regulates bilateral stem cell activity during secondary growth. 🔗 www.pnas.org/doi/10.1073/... #PlantSciences
pnas.org
An AINTEGUMENTA phosphoswitch controls bilateral stem cell activity during secondary growth | PNAS
Plant stem cells have the remarkable ability to give rise to distinct tissues and organs throughout development. Two concentric cylinders of active...
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Houming Chen @hmchen93.bsky.social · 09/08/2025
Happy to share our latest manuscript about Brassinosteroid recognition 😎 hope it offers a broad and intensive understanding of BR ligands--BRI1-LIKE receptors mechanism.
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Reposted by Houming Chen
Michael Hothorn @structplantbio.bsky.social · 09/08/2025
Our latest on brassinosteroid signaling: Ligand binding spectrum, specificity & selectivity of all BR receptors in Arabidopsis. By @albertocaregnato.bsky.social , @hmchen93.bsky.social and our great chemistry collaborators Mirek Kvasnica, Jana Oklestkova and Mirek Strnad.
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Reposted by Houming Chen
Michael Hothorn @structplantbio.bsky.social · 11/07/2025
Nice analysis of ITPK and VIH inositol pyrophophate kinase over-expression lines in Arabidopsis. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Enhancing inositol pyrophosphate accumulation in plants alters growth, phosphate homeostasis, and insect herbivory
This research investigates the physiological and biochemical impacts of increasing inositol pyrophosphates, molecules involved in plant phosphate sensing and jasmonic acid signaling, in Arabidopsis. ...
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Reposted by Houming Chen
Simon Snoeck @simonsnoeck.bsky.social · 09/07/2025
Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges #AlphaFold3, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism. www.biorxiv.org/content/10.1...
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Nature Reviews Molecular Cell Biology @natrevmcb.nature.com · 19/05/2025
New Online! Mechanisms of auxin action in plant growth and development
bit.ly
Mechanisms of auxin action in plant growth and development
Nature Reviews Molecular Cell Biology, Published online: 19 May 2025; doi:10.1038/s41580-025-00851-2The phytohormone auxin coordinates plant growth by forming local maxima and gradients through cell-to-cell transport and metabolic control. Recent research has identified novel signalling mechanisms involving extracellular auxin perception and auxin-mediated cyclic AMP production.
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Houming Chen @hmchen93.bsky.social · 13/05/2025
novel and in-depth work 👍🏻
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Reposted by Houming Chen
Nature Plants @natplants.nature.com · 21/01/2025
New Article: "Structural mechanism underlying PHO1;H1-mediated phosphate transport in Arabidopsis" rdcu.be/d62pA Phosphate transporter PHO1: cryo-EM, biochemical & physiological analysis. Molecular and regulatory mechanism of transport mediated by the SPX–EXS family. #PlantScience
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bioRxiv Plant Bio @biorxiv-plants.bsky.social · 28/11/2024
BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10 www.biorxiv.org/content/10.1101/202…
biorxiv.org
BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10 https://www.biorxiv.org/content/10.1101/2024.11.26.625463v1
After germination, seedlings undergo etiolated development (skotomorphogenesis), enabling them to gr
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Reposted by Houming Chen
Prof. Keiko Torii @keikoutorii.bsky.social · 11/12/2024
Perspectives on a co-option of a familiar signaling pathway for embryo patterning, where phosphorylation of SCREAM by MPK3/6 triggers different outcomes. But..Symmetric Cell Division is EXCITING and essential for generating a mirror-symmetric Guard Cell pair😘🌱. www.nature.com/articles/s41...
nature.com
Yoda screams again - Nature Plants
Nature Plants - Yoda screams again
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Reposted by Houming Chen
Houming Chen @hmchen93.bsky.social · 17/11/2024
Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉 Want to discover the exciting new functions of ICE1/SCRM? Want to dive into the latest model of plant embryo initiation? Don’t miss out—check it out here: nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com
Phosphorylation‐dependent activation of the bHLH transcription factor ICE1/SCRM promotes polarization of the Arabidopsis zygote
In Arabidopsis thaliana, the asymmetric cell division (ACD) of the zygote gives rise to the embryo proper and an extraembryonic suspensor, respectively. This process is controlled by the ERECTA-YODA...
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Houming Chen @hmchen93.bsky.social · 17/11/2024
Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉 Want to discover the exciting new functions of ICE1/SCRM? Want to dive into the latest model of plant embryo initiation? Don’t miss out—check it out here: nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com
Phosphorylation‐dependent activation of the bHLH transcription factor ICE1/SCRM promotes polarization of the Arabidopsis zygote
In Arabidopsis thaliana, the asymmetric cell division (ACD) of the zygote gives rise to the embryo proper and an extraembryonic suspensor, respectively. This process is controlled by the ERECTA-YODA...
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